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Compare train, bus, and flight for Prague to Frankfurt am Main
Omio recommends booking the train as it is the most popular option from Prague to Frankfurt am Main among Omio's users. If you are prioritising price take the bus with prices starting from €25. For those with little time consider booking a flight which can get you there in 3h 26m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.1 - 0.4kg. The ticket price range depends on the travel mode: a bus costs an average of €25, and a flight costs an average of €114.
Distance: 409 km
Compare train with
Most popular Train | Bus | Flight |
|---|---|---|
€76 Average price | €37 Average price Cheapest | €191 Average price |
6h 23m Average total duration 5h 53m Onboard + 30m Additional time* | 6h 57m Average total duration 6h 27m Onboard + 30m Additional time* | 6h 26m Average total duration Fastest 3h 26m Onboard + 3h 0m Additional time* |
0.1 - 0.4kg CO2 emissions Lowest | 0.4 - 1.0kg CO2 emissions | 1.2 - 2.5kg CO2 emissions |
![]() Most popular train company | ![]() Most popular bus company | ![]() Most popular airline |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Travel optionsfrom Prague to Frankfurt am Main
How to get from Prague to Frankfurt am Main by train, bus or flight.
Our recommendation
The best way to travel from Prague to Frankfurt am Main is by taking a bus because it’s the best combination of price and speed.
FlixBus9:10 AM7h35Praha, Na Knížecí4:45 PMFrankfurt, Stuttgarter Straße (Fermomnibusbahnhof)€691One-way0 transfers
Cheapest
FlixBus11:05 PM7h25Praha, ÚAN Florenc6:30 AMFrankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36)€531One-way0 transfers
Fastest
DE44085:00 PM1h00Prague Vaclav Havel Airport6:00 PMFrankfurt am Main Airport€1671One-way0 transfers
Other options
EX 358 · 3568 · ICE 6249:35 AM7h27Prague hlavní nádraží5:02 PMFrankfurt (Main) Hbf€851One-way2 transfers
EX 358 · 3568 · ICE 6249:35 AM7h44Prague hlavní nádraží5:19 PMFrankfurt Airport long-distance station€851One-way2 transfers
EC 358 · R 3568 · ICE 6249:35 AM7h27Prague hlavní nádraží5:02 PMFrankfurt (Main) Hbf€1551One-way2 transfers
FlixBus4:10 AM7h10Praha, Na Knížecí11:20 AMFrankfurt, Stuttgarter Straße (Fermomnibusbahnhof)€611One-way0 transfers
FlixBus8:50 AM7h55Praha, ÚAN Florenc4:45 PMFrankfurt, Stuttgarter Straße (Fermomnibusbahnhof)€691One-way0 transfers
FlixBus10:55 AM8h30Praha, Na Knížecí7:25 PMFrankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36)€671One-way0 transfers
DE44068:50 AM1h00Prague Vaclav Havel Airport9:50 AMFrankfurt am Main Airport€2461One-way0 transfers
LO524 · LO3779:55 AM6h35Prague Vaclav Havel Airport4:30 PMFrankfurt am Main Airport€2561One-way1 transfer
LO528 · LO37912:45 PM6h15Prague Vaclav Havel Airport7:00 PMFrankfurt am Main Airport€2561One-way1 transfer
Find all the dates and times for this journey by train, bus, flight, and ferry .
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FAQs: Travel from Prague to Frankfurt am Main
Travel to Frankfurt am Main easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Prague to Frankfurt am Main.

This is compared to other travel options from Prague to Frankfurt am Main:
A bus is €4 less than a train for this route with tickets for a train from Prague to Frankfurt am Main costing on average €29.
A bus is €89 less than a flight for this route with tickets for a flight from Prague to Frankfurt am Main costing on average €114.
Other travel options to Frankfurt am Main take longer:
Train takes on average 7h 3m.
Bus takes on average 6h 25m.
- Around 50 flights per day.
- Around 30 buses per day.
- Around 15 trains per day.
However, we recommend checking specific travel dates for your route between Prague and Frankfurt am Main as scheduled services by train, bus, and flight can vary by season or day of the week.
- Flights mostly depart from Prague Vaclav Havel Airport and arrive in Frankfurt am Main Airport.
- Trains mostly depart from Prague hlavní nádraží and arrive in Frankfurt (Main) Hbf.
- Buses mostly depart from Praha, ÚAN Florenc and arrive in Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof).
- Travel with FlixBus, BlaBlaCar Bus, Infobus, BlaBlaCar to go to Frankfurt am Main by bus.
- Travel with Deutsche Bahn, České dráhy, Leo Express, ÖBB | Euro City (EC) to go to Frankfurt am Main by train.
- Travel with Lufthansa, Air Dolomiti, Condor Flugdienst, Lot Polish Airlines, Austrian Airlines, KLM, Lufthansa Cityline, KLM Cityhopper, Helvetic Airways to go to Frankfurt am Main by flight.
- 14 direct buses per day with FlixBus, BlaBlaCar Bus, Infobus, BlaBlaCar.
- 0 direct trains per day with ÖBB | Euro City (EC).
- 7 direct flights per day with Lufthansa, Air Dolomiti, Condor Flugdienst, Lufthansa Cityline.
Travelling from Prague to Frankfurt am Main: related information
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