The cheapest and fastest buses from Lyon to Madrid
Cheapest price
€121
Average price
€166
Fastest journey
16 h 10 m
Average duration
18 h 30 m
Buses per day
7
Distance
912 km
The best way to find a cheap bus ticket from Lyon to Madrid is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Lyon to Madrid will cost around €166 if you buy it on the day, but the cheapest tickets can be found for only €121.
Of the 7 buses that leave Lyon for Madrid on Sun, Nov 09, 2 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Sun, Nov 09 the direct buses cover the 912 km distance in an average of 18 h 30 m but if you time it right, some buses will get you there in just 16 h 10 m .
On Sun, Nov 09 the slowest buses will take 22 h 25 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
34153
Normal · Normal
FlixBus
5807 · 4821
5228 · 3163
Normal · Normal
FlixBus
34153
5807 · 4821
5228 · 3163Travel Information
Compare train, bus, and flight for Lyon to Madrid
Omio recommends booking the flight as it is the most popular option from Lyon to Madrid among Omio's users. If you are prioritising price take the bus with prices starting from €40. For those with little time consider booking a flight which can get you there in 3h 1m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.3 - 0.8kg. The ticket price range depends on the travel mode: a bus costs an average of €40, and a flight costs an average of €49.
Distance: 912 km
Compare bus with
| Bus | Most popular Flight | Train |
|---|---|---|
€100 Average price Cheapest | €217 Average price | €153 Average price |
17h 41m Average total duration 17h 11m Onboard + 30m Additional time* | 6h 1m Average total duration Fastest 3h 1m Onboard + 3h 0m Additional time* | 8h 15m Average total duration 7h 45m Onboard + 30m Additional time* |
0.9 - 2.3kg CO2 emissions | 2.7 - 5.5kg CO2 emissions | 0.3 - 0.8kg CO2 emissions Lowest |
![]() Most popular bus company | ![]() Most popular airline | ![]() Most popular train company |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Live departures
Lyon to Madrid bus times
The table below shows live departures for Lyon to Madrid buses for tomorrow, Sunday, November 9. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
5807 · 4821 | 3:40 AM Lyon, Perrache Bus Station | 20h00 | 11:40 PM Madrid, Estación Sur de Autobuses | 1 transfer | |
Normal · Normal | 4:10 AM Lyon, Perrache Bus Station | 16h10 | 8:20 PM Madrid, Terminal de autobuses T4 (Aeropuerto de Madrid) | 1 transfer | |
FlixBus · FlixBus | 7:40 AM Lyon, Perrache Bus Station | 23h40 | 7:20 AM Madrid, Terminal de autobuses T4 (Aeropuerto de Madrid) | 1 transfer | |
FlixBus | 3:00 PM Lyon, Perrache Bus Station | 16h40 | 7:40 AM Madrid, Estación Sur de Autobuses | 0 transfersDirect | |
5228 · 3163 | 3:45 PM Lyon, Perrache Bus Station | 22h25 | 2:10 PM Madrid, Estación Sur de Autobuses | 1 transfer | |
34153 | 7:50 PM Lyon, Perrache Bus Station | 17h15 | 1:05 PM Madrid, Estación Sur de Autobuses | 0 transfersDirect | |
FlixBus · FlixBus · FlixBus | 10:40 PM Lyon, Perrache Bus Station | 32h40 | 7:20 AM Madrid, Terminal de autobuses T4 (Aeropuerto de Madrid) | 2 transfers | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Lyon to Madrid by train, bus, or flight
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Nov 09
Nov 10
Nov 11
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Nov 29
Journey information
Overview: Bus from Lyon to Madrid
Buses from Lyon to Madrid run on average 9 times per day, taking around 17h 11m. Cheap bus tickets for this journey start at €40 if you book in advance.
There are 3 buses per day. The earliest bus runs at 00:05, the last at 23:55. The fastest bus covers the 912 km distance in 15h 55m.
Distance 912 km |
Average bus duration 17h 11m |
Cheapest ticket price €40 |
Buses per day 9 |
Direct buses 3 |
Fastest bus 15h 55m |
First bus 00:05 |
Last bus 23:55 |
Bus providers: BlaBlaCar Bus, Ourbus, Alsa, FlixBus, Infobus, BlaBlaCar, Union Ivkoni - Unibus from Lyon to MadridYou can travel by bus between Lyon to Madrid with BlaBlaCar Bus, Ourbus, Alsa, FlixBus, Infobus, BlaBlaCar, Union Ivkoni - Unibus for as low as €40. When you search for schedules and tickets, Omio will show you the best journey
Alsa
FlixBus
Infobus
BlaBlaCar Bus
Ourbus
BlaBlaCar
Union Ivkoni - Unibus
FAQs: Bus from Lyon to Madrid
Find answers to the most common questions about traveling from Lyon to Madrid by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Madrid, this guide helps you travel smarter and with confidence.

When departing from Lyon, you have various coach station options to start your trip from including Lyon, Perrache Bus Station, Lyon, Gare Perrache and Lyon, Perrache (Brasserie Georges). When arriving in Madrid, you can end your journey in coach stations like Madrid, Estación Sur de Autobuses, Madrid, Aeropuerto Barajas T4 and Madrid, Estación Sur/Gare routière Méndez Alvaro - 83.
Passengers board the coach most frequently from Lyon, Perrache Bus Station, which is located around 1.2 miles (1.9 km) away from the city centre, and they get off the coach at Madrid, Estación Sur de Autobuses, located 3.1 miles (5 km) away from the city centre.
popular bus stations
Popular bus stations from Lyon to Madrid
- 06:00-23:00
- Free Wi-Fi
- Café de la Gare (in the station)
- Bistro Lyonnais (0.2 km)
- Fast Food Express (0.3 km).
- Available outside the main entrance.
- Elevators, ramps
- Available on the concourse.
- Bus: C21, C22, S1 Metro: A Train: TER
- 06:00-23:00
- Free Wi-Fi
- Café de la Gare (in the station)
- Le Bistrot de Lyon (0.5 km)
- Brasserie Georges (0.6 km).
- Available outside the main entrance.
- Elevators, ramps
- Available in the station.
- Bus: C19, C20, 31, 46, 49, 55, 60, S1 Metro: A Tram: T1, T2
- 06:00-23:00
- Free Wi-Fi
- Cafetería de la estación (in the station)
- Restaurante El Rincón (0.5 km)
- La Vaca Argentina (0.7 km).
- Available outside the main entrance.
- Elevators, ramps
- Available in the station.
- Bus: 200, 114, 115, 122 Metro: 4, 6, 7, 9
- 06:00-23:00
- Free Wi-Fi
- Cafetería de la estación (in the station)
- Restaurante El Brillante (0.5 km)
- La Taberna de Domínguez (0.7 km).
- Available outside the main entrance.
- Elevators, ramps
- Available in the station.
- Bus: 8, 102, 148 Metro: L6 Train: C1, C5
Most popular bus connections from Lyon
More options for your journey from Lyon to Madrid
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