The cheapest and fastest buses from Messina to Rome
Cheapest price
€20
Average price
€38
Fastest journey
9 h
Average duration
9 h 49 m
Buses per day
6
Distance
487 km
The best way to find a cheap bus ticket from Messina to Rome is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Messina to Rome will cost around €38 if you buy it on the day, but the cheapest tickets can be found for only €20.
Of the 6 buses that leave Messina for Rome on Wed, Apr 22, 5 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Wed, Apr 22 the direct buses cover the 487 km distance in an average of 9 h 49 m but if you time it right, some buses will get you there in just 9 h .
On Wed, Apr 22 the slowest buses will take 10 h 35 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
21269:35 PM10h10Messina, Piazza Della Repubblica (Stazione Centrale)7:45 AMRoma, Autostazione Tiburtina€201One-way0 transfers
FlixBus9:30 PM9h20Messina, Piazza Della Repubblica (Stazione Centrale)6:50 AMRoma, Autostazione Tiburtina€241One-way0 transfers
FlixBus1:30 AM10h00Messina, Piazza Della Repubblica (Stazione Centrale)11:30 AMRoma, Autostazione Tiburtina€241One-way0 transfers
FlixBus10:55 AM10h35Messina, Piazza Della Repubblica (Stazione Centrale)9:30 PMRoma, Autostazione Tiburtina€391One-way0 transfers
FlixBus · FlixBus4:10 PM13h25Messina, Piazza Della Repubblica (Stazione Centrale)5:35 AMRoma, Autostazione Tiburtina€601One-way1 transfer
S2029:15 PM9h00Messina, Piazza Della Repubblica (Stazione Centrale)6:15 AMRoma, Autostazione Tiburtina€621One-way0 transfers
FlixBus9:30 PM9h20Messina, Piazza Della Repubblica (Stazione Centrale)6:50 AMRoma, Autostazione Tiburtina€241One-way0 transfers
FlixBus1:30 AM10h00Messina, Piazza Della Repubblica (Stazione Centrale)11:30 AMRoma, Autostazione Tiburtina€241One-way0 transfers
21269:35 PM10h10Messina, Piazza Della Repubblica (Stazione Centrale)7:45 AMRoma, Autostazione Tiburtina€201One-way0 transfers
FlixBus10:55 AM10h35Messina, Piazza Della Repubblica (Stazione Centrale)9:30 PMRoma, Autostazione Tiburtina€391One-way0 transfers
Travel Information
Compare train, bus, and flight for Messina to Rome
Omio recommends booking the bus as it is the most popular option from Messina to Rome among Omio's users. If you are prioritising price take the bus with prices starting from €14. For those with little time consider booking a flight which can get you there in 1h 23m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.1 - 0.4kg. The ticket price range depends on the travel mode: a bus costs an average of €14, and a train costs an average of €32.
Distance: 487 km
Compare bus with
Most popular Bus | Train | Flight |
|---|---|---|
€36 Average price Cheapest | €67 Average price | €42 Average price |
9h 53m Average total duration 9h 23m Onboard + 30m Additional time* | 8h 1m Average total duration 7h 31m Onboard + 30m Additional time* | 4h 23m Average total duration Fastest 1h 23m Onboard + 3h 0m Additional time* |
0.5 - 1.2kg CO2 emissions | 0.1 - 0.4kg CO2 emissions Lowest | 1.5 - 2.9kg CO2 emissions |
![]() Most popular bus company | ![]() Most popular train company | ![]() Most popular airline |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Live departures
Messina to Rome bus times
The table below shows live departures for Messina to Rome buses for today, Tuesday, April 21. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
FlixBus · FlixBus | 4:10 PM Messina, Piazza Della Repubblica (Stazione Centrale) | 13h25 | 5:35 AM Roma, Autostazione Tiburtina | 1 transfer | |
S202 | 9:15 PM Messina, Piazza Della Repubblica (Stazione Centrale) | 9h00 | 6:15 AM Roma, Autostazione Tiburtina | 0 transfersDirect | |
FlixBus | 9:30 PM Messina, Piazza Della Repubblica (Stazione Centrale) | 9h20 | 6:50 AM Roma, Autostazione Tiburtina | 0 transfersDirect | |
2126 | 9:35 PM Messina, Piazza Della Repubblica (Stazione Centrale) | 10h10 | 7:45 AM Roma, Autostazione Tiburtina | 0 transfersDirect | |
4412 | 11:50 PM Messina, Piazza Della Repubblica (Stazione Centrale) | 14h30 | 2:20 PM Roma, Autostazione Tiburtina | 0 transfersDirect | |
FlixBus | 1:30 AM Messina, Piazza Della Repubblica (Stazione Centrale) | 10h00 | 11:30 AM Roma, Autostazione Tiburtina | 0 transfersDirect | |
| Wednesday, April 22 | |||||
FlixBus | 10:55 AM Messina, Piazza Della Repubblica (Stazione Centrale) | 10h35 | 9:30 PM Roma, Autostazione Tiburtina | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Messina to Rome by train, bus, or flight
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Apr 22
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Apr 30
May 01
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Why should you book Messina to Rome buses with Omio?
Why book with Omio vs Itabus?
- Compare with other providers: On Omio, you can not only buy tickets for Itabus, but also compare tickets for the likes of FlixBus, Autoservizi Salemi, Infobus or Salemi to find the best option for your trip from Messina to Rome.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Itabus with all available travel options, which are train, bus and flight to ensure you get the best deal for traveling from Messina to Rome.
Why book with Omio over Checkmybus, Wanderu or Trainline?
- Compare with other providers: On Omio, you can also compare tickets for the likes of FlixBus, Autoservizi Salemi, Infobus or Salemi to find the best option for your trip from Messina to Rome.
- Multiple modes of transport: Omio allows you to compare travel options including train, bus and flight to find the ideal travel option from Messina to Rome.
Journey information
Overview: Bus from Messina to Rome
Buses from Messina to Rome run on average 7 times per day, taking around 9h 23m. Cheap bus tickets for this journey start at €14 if you book in advance.
There are 6 buses per day. The earliest bus runs at 00:15, the last at 23:50. The fastest bus covers the 487 km distance in 9h 0m.
Distance 487 km |
Average bus duration 9h 23m |
Cheapest ticket price €14 |
Buses per day 7 |
Direct buses 6 |
Fastest bus 9h 0m |
First bus 12:15 AM |
Last bus 11:50 PM |
Cheapest Month Aug |
Cheapest Day Sat |
High Season Jul - Sep |
Low Season Jan - Mar |
Busiest Day Thu |
Least Busy Day Wed |
Best time to book 42 days |
Bus providers: Itabus, FlixBus, Autoservizi Salemi, BlaBlaCar, Infobus, Salemi, Autoservizi Salemi Srl, SAIS trasporti S.p.A. - Autolinee Giamporcaro from Messina to RomeYou can travel by bus between Messina to Rome with Itabus, FlixBus, Autoservizi Salemi, BlaBlaCar, Infobus, Salemi, Autoservizi Salemi Srl, SAIS trasporti S.p.A. - Autolinee Giamporcaro for as low as €14. When you search for schedules and tickets, Omio will show you the best journey
Itabus
FlixBus
Infobus
Autoservizi Salemi
BlaBlaCar
Salemi
Autoservizi Salemi Srl
SAIS trasporti S.p.A. - Autolinee Giamporcaro
FAQs: Bus from Messina to Rome
Find answers to the most common questions about traveling from Messina to Rome by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Rome, this guide helps you travel smarter and with confidence.

- Infobus
- Assistance
- Priority seating
- Transport for wheelchairs and mobility aids.
- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
- Itabus
- Assistance
- Dedicated seating areas
- Accessible restrooms.
- Autoservizi Salemi
- The cancellation policy can vary by ticket class, individual trips, or promotions, so it's best to check the terms during booking.
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
- Itabus
- You can cancel your ticket up to 24 hours before departure for a partial refund. Changes allowed for a fee.
- Autoservizi Salemi
- Two pieces of luggage: one large suitcase for the hold and one smaller backpack for on-board.
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
- Itabus
- One carry-on bag up to 10kg and one checked bag up to 20kg.
- Infobus
- 10€ per additional bag.
- FlixBus
- Additional luggage can be purchased for a fee.
- Itabus
- 5€ per additional bag.
- Infobus
- Small pets allowed in carriers
- larger pets may require a separate ticket.
- FlixBus
- Small pets in carriers allowed
- guide dogs travel for free.
- Itabus
- Small pets allowed in carriers
- larger pets must be leashed and muzzled.
popular bus stations
Popular bus stations from Messina to Rome
- 06:00-23:00
- Free Wi-Fi
- Ristorante Italiano (in the station)
- Fast Food Express (in the station)
- Caffè del Terminal (in the station).
- Available outside the arrivals terminal.
- Elevators, ramps
- Available in the station.
- Bus: 520, 720 Train: Leonardo Express
More options for your journey from Messina to Rome
Here are some other resources that might have the information you need


