The cheapest and fastest buses from Milan Centrale to Rome
Cheapest price
€10
Average price
€29
Fastest journey
5 h 30 m
Average duration
6 h 15 m
Buses per day
56
Distance
478 km
The best way to find a cheap bus ticket from Milan Centrale to Rome is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Milan Centrale to Rome will cost around €29 if you buy it on the day, but the cheapest tickets can be found for only €10.
Of the 56 buses that leave Milan Centrale for Rome on Mon, Feb 23, 43 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Mon, Feb 23 the direct buses cover the 478 km distance in an average of 6 h 15 m but if you time it right, some buses will get you there in just 5 h 30 m .
On Mon, Feb 23 the slowest buses will take 7 h 35 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
3803
3491
3811
3825
FlixBus



FlixBusTravel Information
Compare train, bus, and flight for Milan Centrale to Rome
Omio recommends booking the train as it is the most popular option from Milan Centrale to Rome among Omio's users. If you are prioritising price take the bus with prices starting from €7. For those with little time consider booking a flight which can get you there in 2h 29m. The ticket price range depends on the travel mode: a bus costs an average of €7, and a flight costs an average of €56.
Distance: 478 km
Compare bus with
| Bus | Most popular Train | Flight |
|---|---|---|
€17 Average price Cheapest | €51 Average price | €120 Average price |
9h 10m Average total duration 8h 40m Onboard + 30m Additional time* | 6h 22m Average total duration 5h 52m Onboard + 30m Additional time* | 5h 29m Average total duration Fastest 2h 29m Onboard + 3h 0m Additional time* |
![]() Most popular bus company | ![]() Most popular train company | ![]() Most popular airline |
Direct Options | Direct Options | Direct Options |
Live departures
Milan Centrale to Rome bus times
The table below shows live departures for Milan Centrale to Rome buses for today, Sunday, February 22. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
FlixBus · FlixBus | 8:50 PM Milano, San Donato - Settore B (Viale Giuseppe Impastato) | 11h30 | 8:20 AM Roma, Autostazione Tiburtina | 1 transfer | |
3897 | 9:30 PM Milano, Autostazione Lampugnano | 8h30 | 6:00 AM Roma, Autostazione Tiburtina | 0 transfersDirect | |
2495 | 9:40 PM Milano, Autostazione Lampugnano | 9h25 | 7:05 AM Roma, Autostazione Tiburtina | 0 transfersDirect | |
FlixBus · FlixBus | 9:45 PM Milano, Autostazione Lampugnano | 11h40 | 9:25 AM Roma, Autostazione Tiburtina | 1 transfer | |
FlixBus | 10:05 PM Sesto San Giovanni, Piazza Primo Maggio (Stazione ferroviaria) | 11h45 | 9:50 AM Roma, Autostazione Tiburtina | 0 transfersDirect | |
FlixBus · FlixBus | 10:20 PM Milano, San Donato - Settore B (Viale Giuseppe Impastato) | 11h05 | 9:25 AM Roma, Autostazione Tiburtina | 1 transfer | |
3825 | 10:45 PM Milano, Autostazione Lampugnano | 9h05 | 7:50 AM Roma, Autostazione Tiburtina | 0 transfersDirect | |
FlixBus | 11:50 PM Assago, Viale Milanofiori (Assago M2) | 10h00 | 9:50 AM Roma, Autostazione Tiburtina | 0 transfersDirect | |
| Monday, February 23 | |||||
FlixBus · FlixBus | 1:25 AM Milano, Autostazione Lampugnano | 9h50 | 11:15 AM Roma, Autostazione (Metro Anagnina) | 1 transfer | |
FlixBus | 1:25 AM Milano, Autostazione Lampugnano | 7h35 | 9:00 AM Roma, Autostazione Tiburtina | 0 transfersDirect | |
FlixBus | 4:15 AM Milano, Autostazione Lampugnano | 8h35 | 12:50 PM Roma, Autostazione Tiburtina | 0 transfersDirect | |
FlixBus · FlixBus | 4:35 AM Milano, Autostazione Lampugnano | 9h30 | 2:05 PM Roma, Autostazione (Metro Anagnina) | 1 transfer | |
FlixBus | 5:15 AM Milano, Autostazione Lampugnano | 9h05 | 2:20 PM Roma, Autostazione Tiburtina | 0 transfersDirect | |
FlixBus | 5:50 AM Milano, San Donato - Settore B (Viale Giuseppe Impastato) | 8h30 | 2:20 PM Roma, Autostazione Tiburtina | 0 transfersDirect | |
FlixBus · FlixBus | 6:25 AM Milano, Autostazione Lampugnano | 10h35 | 5:00 PM Roma, Autostazione (Metro Anagnina) | 1 transfer | |
FlixBus · FlixBus | 6:55 AM Milano, Autostazione Lampugnano | 10h10 | 5:05 PM Roma, Autostazione (Metro Anagnina) | 1 transfer | |
FlixBus | 6:55 AM Milano, Autostazione Lampugnano | 8h35 | 3:30 PM Roma, Autostazione Tiburtina | 0 transfersDirect | |
FlixBus | 7:15 AM Milano, Autostazione Lampugnano | 10h20 | 5:35 PM Roma, Autostazione Tiburtina | 0 transfersDirect | |
FlixBus · FlixBus | 7:15 AM Milano, San Donato - Settore B (Viale Giuseppe Impastato) | 9h45 | 5:00 PM Roma, Autostazione (Metro Anagnina) | 1 transfer | |
FlixBus | 7:20 AM Milano, Autostazione Lampugnano | 9h25 | 4:45 PM Roma, Autostazione Tiburtina | 0 transfersDirect | |
FlixBus · FlixBus | 7:50 AM Milano, San Donato - Settore B (Viale Giuseppe Impastato) | 9h15 | 5:05 PM Roma, Autostazione (Metro Anagnina) | 1 transfer | |
FlixBus | 7:50 AM Milano, San Donato - Settore B (Viale Giuseppe Impastato) | 7h40 | 3:30 PM Roma, Autostazione Tiburtina | 0 transfersDirect | |
3801 | 7:55 AM Milano, Autostazione Lampugnano | 8h35 | 4:30 PM Roma, Autostazione Tiburtina | 0 transfersDirect | |
FlixBus | 8:05 AM Assago, Viale Milanofiori (Assago M2) | 8h40 | 4:45 PM Roma, Autostazione Tiburtina | 0 transfersDirect | |
FlixBus | 9:30 AM Milano, Autostazione Lampugnano | 8h15 | 5:45 PM Roma, Autostazione Tiburtina | 0 transfersDirect | |
2125 | 9:40 AM Milano, Autostazione Lampugnano | 8h35 | 6:15 PM Roma, Autostazione Tiburtina | 0 transfersDirect | |
3811 | 10:30 AM Milano, Autostazione Lampugnano | 9h15 | 7:45 PM Roma, Autostazione Tiburtina | 0 transfersDirect | |
FlixBus | 10:55 AM Milano, Autostazione Lampugnano | 8h25 | 7:20 PM Roma, Autostazione Tiburtina | 0 transfersDirect | |
FlixBus | 11:00 AM Milano, Autostazione Lampugnano | 10h35 | 9:35 PM Roma, Autostazione Tiburtina | 0 transfersDirect | |
FlixBus | 11:25 AM Milano, Autostazione Lampugnano | 8h45 | 8:10 PM Roma, Autostazione Tiburtina | 0 transfersDirect | |
FlixBus | 11:30 AM Assago, Viale Milanofiori (Assago M2) | 10h05 | 9:35 PM Roma, Autostazione Tiburtina | 0 transfersDirect | |
FlixBus | 11:40 AM Milano, Autostazione Lampugnano | 9h45 | 9:25 PM Roma, Autostazione Tiburtina | 0 transfersDirect | |
FlixBus | 11:45 AM Milano, San Donato - Settore B (Viale Giuseppe Impastato) | 7h35 | 7:20 PM Roma, Autostazione Tiburtina | 0 transfersDirect | |
3803 | 11:50 AM Milano, Autostazione Lampugnano | 8h20 | 8:10 PM Roma, Autostazione Tiburtina | 0 transfersDirect | |
FlixBus · FlixBus | 1:20 PM Sesto San Giovanni, Piazza Primo Maggio (Stazione ferroviaria) | 9h15 | 10:35 PM Roma, Autostazione Tiburtina | 1 transfer | |
FlixBus · FlixBus | 1:45 PM Milano, San Donato - Settore B (Viale Giuseppe Impastato) | 8h50 | 10:35 PM Roma, Autostazione Tiburtina | 1 transfer | |
110 | 2:10 PM Milano, Autostazione Lampugnano | 8h30 | 10:40 PM Roma, Autostazione Tiburtina | 0 transfersDirect | |
FlixBus | 2:15 PM Milano, Autostazione Lampugnano | 8h20 | 10:35 PM Roma, Autostazione Tiburtina | 0 transfersDirect | |
FlixBus | 2:50 PM Assago, Viale Milanofiori (Assago M2) | 7h45 | 10:35 PM Roma, Autostazione Tiburtina | 0 transfersDirect | |
3491 | 3:00 PM Milano, Autostazione Lampugnano | 7h45 | 10:45 PM Roma, Autostazione Tiburtina | 0 transfersDirect | |
FlixBus | 3:20 PM Milano, Autostazione Lampugnano | 8h50 | 12:10 AM Roma, Autostazione Tiburtina | 0 transfersDirect | |
FlixBus | 4:05 PM Milano, San Donato - Settore B (Viale Giuseppe Impastato) | 8h05 | 12:10 AM Roma, Autostazione Tiburtina | 0 transfersDirect | |
FlixBus · FlixBus | 5:25 PM Milano, Autostazione Lampugnano | 9h35 | 3:00 AM Roma, Autostazione Tiburtina | 1 transfer | |
FlixBus · FlixBus | 6:10 PM Milano, San Donato - Settore B (Viale Giuseppe Impastato) | 8h50 | 3:00 AM Roma, Autostazione Tiburtina | 1 transfer | |
2213 · 2413 | 6:20 PM Milano, Autostazione Lampugnano | 9h10 | 3:30 AM Roma, Autostazione Tiburtina | 1 transfer | |
2213 · 2421 | 6:20 PM Milano, Autostazione Lampugnano | 10h05 | 4:25 AM Roma, Autostazione Tiburtina | 1 transfer | |
055 | 7:25 PM Milano, Autostazione Lampugnano | 8h05 | 3:30 AM Roma, Autostazione Tiburtina | 0 transfersDirect | |
FlixBus | 7:30 PM Milano, Autostazione Lampugnano | 9h35 | 5:05 AM Roma, Autostazione (Metro Anagnina) | 0 transfersDirect | |
FlixBus | 7:30 PM Milano, Autostazione Lampugnano | 9h05 | 4:35 AM Roma, Autostazione Tiburtina | 0 transfersDirect | |
FlixBus | 8:00 PM Sesto San Giovanni, Piazza Primo Maggio (Stazione ferroviaria) | 9h05 | 5:05 AM Roma, Autostazione (Metro Anagnina) | 0 transfersDirect | |
FlixBus | 8:00 PM Sesto San Giovanni, Piazza Primo Maggio (Stazione ferroviaria) | 8h35 | 4:35 AM Roma, Autostazione Tiburtina | 0 transfersDirect | |
FlixBus · FlixBus | 8:20 PM Milano, San Donato - Settore B (Viale Giuseppe Impastato) | 8h50 | 5:10 AM Roma, Autostazione Tiburtina | 1 transfer | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Milan Centrale to Rome by train, bus, or flight
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Feb 22
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Feb 28
Mar 01
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Mar 09
Mar 10
Mar 11
Mar 12
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Mar 14
Why should you book Milan Centrale to Rome buses with Omio?
Why book with Omio vs FlixBus?
- Compare with other providers: On Omio, you can not only buy tickets for FlixBus, but also compare tickets for the likes of Itabus, BlaBlaCar Bus, Marino Autolinee or Infobus to find the best option for your trip from Milan Centrale to Rome.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare FlixBus with all available travel options, which are train, bus and flight to ensure you get the best deal for traveling from Milan Centrale to Rome.
Why book with Omio over Wanderu, Trainline or Checkmybus?
- Compare with other providers: On Omio, you can also compare tickets for the likes of Itabus, BlaBlaCar Bus, Marino Autolinee or Infobus to find the best option for your trip from Milan Centrale to Rome.
- Multiple modes of transport: Omio allows you to compare travel options including train, bus and flight to find the ideal travel option from Milan Centrale to Rome.
Journey information
Overview: Bus from Milan Centrale to Rome
Buses from Milan Centrale to Rome run on average 32 times per day, taking around 8h 40m. Cheap bus tickets for this journey start at €7 if you book in advance.
There are 24 buses per day. The earliest bus runs at 04:15, the last at 23:50. The fastest bus covers the 478 km distance in 7h 45m.
Distance 478 km |
Average bus duration 8h 40m |
Cheapest ticket price €7 |
Buses per day 32 |
Direct buses 24 |
Fastest bus 7h 45m |
First bus 04:15 |
Last bus 23:50 |
Bus providers: FlixBus, Itabus, BlaBlaCar, BlaBlaCar Bus, Marino Autolinee, Infobus, Autoservizi Salemi, ATM from Milan Centrale to RomeYou can travel by bus between Milan Centrale to Rome with FlixBus, Itabus, BlaBlaCar, BlaBlaCar Bus, Marino Autolinee, Infobus, Autoservizi Salemi, ATM for as low as €7. When you search for schedules and tickets, Omio will show you the best journey
FlixBus
Itabus
Marino Autolinee
Infobus
BlaBlaCar Bus
Autoservizi Salemi
BlaBlaCar
ATM
FAQs: Bus from Milan Centrale to Rome
Find answers to the most common questions about traveling from Milan Centrale to Rome by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Rome, this guide helps you travel smarter and with confidence.

- BlaBlaCar Bus
- Assistance
- Priority boarding
- Accessible seating options.
- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
- Itabus
- Assistance
- Dedicated seating areas
- Accessible restrooms.
- BlaBlaCar Bus
- You can cancel your ticket up to 30 minutes before departure for a refund in the form of a voucher.
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
- Itabus
- You can cancel your ticket up to 24 hours before departure for a partial refund. Changes allowed for a fee.
- BlaBlaCar Bus
- One carry-on bag up to 7kg and one checked bag up to 20kg.
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
- Itabus
- One carry-on bag up to 10kg and one checked bag up to 20kg.
- BlaBlaCar Bus
- Additional luggage can be purchased for a fee.
- FlixBus
- Additional luggage can be purchased for a fee.
- Itabus
- 5€ per additional bag.
- Marino Autolinee
- Small pets allowed in carriers
- larger pets must be leashed and muzzled.
- FlixBus
- Small pets in carriers allowed
- guide dogs travel for free.
- Itabus
- Small pets allowed in carriers
- larger pets must be leashed and muzzled.
popular bus stations
Popular bus stations from Milan Centrale to Rome
Most popular bus connections from Milan Centrale
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