The cheapest and fastest buses from Milan Centrale to Rome
Cheapest price
€8
Average price
€25
Fastest journey
7 h 25 m
Average duration
7 h 39 m
Buses per day
56
Distance
478 km
The best way to find a cheap bus ticket from Milan Centrale to Rome is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Milan Centrale to Rome will cost around €25 if you buy it on the day, but the cheapest tickets can be found for only €8.
Of the 56 buses that leave Milan Centrale for Rome on Mon, May 25, 41 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Mon, May 25 the direct buses cover the 478 km distance in an average of 7 h 39 m but if you time it right, some buses will get you there in just 7 h 25 m .
On Mon, May 25 the slowest buses will take 7 h 50 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
212510:40 AM8h35Milano, Autostazione Lampugnano7:15 PMRoma, Autostazione Tiburtina€81One-way0 transfers
34914:00 PM7h45Milano, Autostazione Lampugnano11:45 PMRoma, Autostazione Tiburtina€81One-way0 transfers
382511:45 PM9h05Milano, Autostazione Lampugnano8:50 AMRoma, Autostazione Tiburtina€91One-way0 transfers
380312:50 PM8h20Milano, Autostazione Lampugnano9:10 PMRoma, Autostazione Tiburtina€91One-way0 transfers
FlixBus3:15 PM8h25Milano, Autostazione Lampugnano11:40 PMRoma, Autostazione Tiburtina€101One-way0 transfers
0559:05 PM7h25Milano, San Donato - Settore B (Viale Giuseppe Impastato)4:30 AMRoma, Autostazione Tiburtina€591One-way0 transfers
FlixBus12:45 PM7h35Milano, San Donato - Settore B (Viale Giuseppe Impastato)8:20 PMRoma, Autostazione Tiburtina€101One-way0 transfers
FlixBus8:50 AM7h40Milano, San Donato - Settore B (Viale Giuseppe Impastato)4:30 PMRoma, Autostazione Tiburtina€111One-way0 transfers
34914:00 PM7h45Milano, Autostazione Lampugnano11:45 PMRoma, Autostazione Tiburtina€81One-way0 transfers
FlixBus3:50 PM7h50Assago, Viale Milanofiori (Assago M2)11:40 PMRoma, Autostazione Tiburtina€101One-way0 transfers
Travel Information
Compare train, bus, and flight for Milan Centrale to Rome
Omio recommends booking the train as it is the most popular option from Milan Centrale to Rome among Omio's users. If you are prioritising price take the bus with prices starting from €6. For those with little time consider booking a flight which can get you there in 2h 29m. The ticket price range depends on the travel mode: a bus costs an average of €6, and a flight costs an average of €53.
Distance: 478 km
Compare bus with
| Bus | Most popular Train | Flight |
|---|---|---|
€19 Average price Cheapest | €55 Average price | €148 Average price |
8h 41m Average total duration 8h 11m Onboard + 30m Additional time* | 6h 24m Average total duration 5h 54m Onboard + 30m Additional time* | 5h 29m Average total duration Fastest 2h 29m Onboard + 3h 0m Additional time* |
![]() Most popular bus company | ![]() Most popular train company | ![]() Most popular airline |
Direct Options | Direct Options | Direct Options |
Live departures
Milan Centrale to Rome bus times
The table below shows live departures for Milan Centrale to Rome buses for today, Sunday, May 24. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
FlixBus · FlixBus | 2:20 PM Sesto San Giovanni, Piazza Primo Maggio (Stazione ferroviaria) | 8h40 | 11:00 PM Roma, Autostazione Tiburtina | 1 transfer | |
FlixBus · FlixBus | 2:45 PM Milano, San Donato - Settore B (Viale Giuseppe Impastato) | 8h15 | 11:00 PM Roma, Autostazione Tiburtina | 1 transfer | |
110 | 3:10 PM Milano, Autostazione Lampugnano | 8h30 | 11:40 PM Roma, Autostazione Tiburtina | 0 transfersDirect | |
FlixBus | 3:15 PM Milano, Autostazione Lampugnano | 8h25 | 11:40 PM Roma, Autostazione Tiburtina | 0 transfersDirect | |
FlixBus | 3:50 PM Assago, Viale Milanofiori (Assago M2) | 7h50 | 11:40 PM Roma, Autostazione Tiburtina | 0 transfersDirect | |
3491 | 4:00 PM Milano, Autostazione Lampugnano | 7h45 | 11:45 PM Roma, Autostazione Tiburtina | 0 transfersDirect | |
FlixBus · FlixBus | 4:40 PM Milano, Autostazione Lampugnano | 8h30 | 1:10 AM Roma, Autostazione Tiburtina | 1 transfer | |
FlixBus · FlixBus | 5:25 PM Milano, San Donato - Settore B (Viale Giuseppe Impastato) | 7h45 | 1:10 AM Roma, Autostazione Tiburtina | 1 transfer | |
2213 · 2421 | 7:20 PM Milano, Autostazione Lampugnano | 10h05 | 5:25 AM Roma, Autostazione Tiburtina | 1 transfer | |
2213 · 2413 | 7:20 PM Milano, Autostazione Lampugnano | 9h10 | 4:30 AM Roma, Autostazione Tiburtina | 1 transfer | |
2213 · 2771 | 7:20 PM Milano, Autostazione Lampugnano | 9h35 | 4:55 AM Roma, Autostazione Tiburtina | 1 transfer | |
055 | 8:25 PM Milano, Autostazione Lampugnano | 8h05 | 4:30 AM Roma, Autostazione Tiburtina | 0 transfersDirect | |
3505 | 8:25 PM Milano, Autostazione Lampugnano | 9h40 | 6:05 AM Roma, Autostazione Tiburtina | 0 transfersDirect | |
FlixBus · FlixBus | 8:35 PM Milano, Autostazione Lampugnano | 9h35 | 6:10 AM Roma, Autostazione Tiburtina | 1 transfer | |
055 | 9:05 PM Milano, San Donato - Settore B (Viale Giuseppe Impastato) | 7h25 | 4:30 AM Roma, Autostazione Tiburtina | 0 transfersDirect | |
FlixBus · FlixBus | 9:10 PM Milano, San Donato - Settore B (Viale Giuseppe Impastato) | 9h00 | 6:10 AM Roma, Autostazione Tiburtina | 1 transfer | |
FlixBus · FlixBus | 9:15 PM Milano, San Donato - Settore B (Viale Giuseppe Impastato) | 10h25 | 7:40 AM Roma, Autostazione Tiburtina | 1 transfer | |
3897 | 10:30 PM Milano, Autostazione Lampugnano | 8h30 | 7:00 AM Roma, Autostazione Tiburtina | 0 transfersDirect | |
2495 | 10:40 PM Milano, Autostazione Lampugnano | 9h25 | 8:05 AM Roma, Autostazione Tiburtina | 0 transfersDirect | |
FlixBus | 11:05 PM Milano, Autostazione Lampugnano | 9h25 | 8:30 AM Roma, Autostazione Tiburtina | 0 transfersDirect | |
3825 | 11:45 PM Milano, Autostazione Lampugnano | 9h05 | 8:50 AM Roma, Autostazione Tiburtina | 0 transfersDirect | |
FlixBus | 11:50 PM Milano, San Donato - Settore B (Viale Giuseppe Impastato) | 8h40 | 8:30 AM Roma, Autostazione Tiburtina | 0 transfersDirect | |
| Monday, May 25 | |||||
FlixBus | 12:50 AM Assago, Viale Milanofiori (Assago M2) | 10h00 | 10:50 AM Roma, Autostazione Tiburtina | 0 transfersDirect | |
FlixBus · FlixBus | 2:40 AM Milano, Autostazione Lampugnano | 10h40 | 1:20 PM Roma, Autostazione Tiburtina | 1 transfer | |
FlixBus | 5:15 AM Milano, Autostazione Lampugnano | 8h35 | 1:50 PM Roma, Autostazione Tiburtina | 0 transfersDirect | |
FlixBus · FlixBus | 5:35 AM Milano, Autostazione Lampugnano | 9h30 | 3:05 PM Roma, Autostazione (Metro Anagnina) | 1 transfer | |
FlixBus | 6:15 AM Milano, Autostazione Lampugnano | 9h05 | 3:20 PM Roma, Autostazione Tiburtina | 0 transfersDirect | |
FlixBus · FlixBus | 6:35 AM Sesto San Giovanni, Piazza Primo Maggio (Stazione ferroviaria) | 10h50 | 5:25 PM Roma, Autostazione Tiburtina | 1 transfer | |
FlixBus | 6:50 AM Milano, San Donato - Settore B (Viale Giuseppe Impastato) | 8h30 | 3:20 PM Roma, Autostazione Tiburtina | 0 transfersDirect | |
FlixBus | 7:55 AM Milano, Autostazione Lampugnano | 8h35 | 4:30 PM Roma, Autostazione Tiburtina | 0 transfersDirect | |
FlixBus · FlixBus | 8:10 AM Milano, San Donato - Settore B (Viale Giuseppe Impastato) | 9h50 | 6:00 PM Roma, Autostazione (Metro Anagnina) | 1 transfer | |
FlixBus | 8:15 AM Milano, Autostazione Lampugnano | 10h20 | 6:35 PM Roma, Autostazione Tiburtina | 0 transfersDirect | |
FlixBus | 8:20 AM Milano, Autostazione Lampugnano | 9h25 | 5:45 PM Roma, Autostazione Tiburtina | 0 transfersDirect | |
FlixBus · FlixBus | 8:20 AM Milano, Autostazione Lampugnano | 9h45 | 6:05 PM Roma, Autostazione (Metro Anagnina) | 1 transfer | |
FlixBus | 8:50 AM Milano, San Donato - Settore B (Viale Giuseppe Impastato) | 7h40 | 4:30 PM Roma, Autostazione Tiburtina | 0 transfersDirect | |
3801 | 8:55 AM Milano, Autostazione Lampugnano | 8h35 | 5:30 PM Roma, Autostazione Tiburtina | 0 transfersDirect | |
FlixBus | 9:05 AM Assago, Viale Milanofiori (Assago M2) | 8h40 | 5:45 PM Roma, Autostazione Tiburtina | 0 transfersDirect | |
FlixBus · FlixBus | 9:05 AM Assago, Viale Milanofiori (Assago M2) | 9h00 | 6:05 PM Roma, Autostazione (Metro Anagnina) | 1 transfer | |
FlixBus · FlixBus | 9:40 AM Milano, San Donato - Settore B (Viale Giuseppe Impastato) | 8h25 | 6:05 PM Roma, Autostazione (Metro Anagnina) | 1 transfer | |
700 | 10:00 AM Milano, Autostazione Lampugnano | 10h00 | 8:00 PM Roma, Autostazione Tiburtina | 0 transfersDirect | |
FlixBus | 10:30 AM Milano, Autostazione Lampugnano | 8h15 | 6:45 PM Roma, Autostazione Tiburtina | 0 transfersDirect | |
2125 | 10:40 AM Milano, Autostazione Lampugnano | 8h35 | 7:15 PM Roma, Autostazione Tiburtina | 0 transfersDirect | |
700 | 10:45 AM Milano, San Donato M3 | 9h15 | 8:00 PM Roma, Autostazione Tiburtina | 0 transfersDirect | |
FlixBus | 11:55 AM Milano, Autostazione Lampugnano | 8h25 | 8:20 PM Roma, Autostazione Tiburtina | 0 transfersDirect | |
FlixBus | 12:00 PM Milano, Autostazione Lampugnano | 10h35 | 10:35 PM Roma, Autostazione Tiburtina | 0 transfersDirect | |
FlixBus | 12:25 PM Milano, Autostazione Lampugnano | 8h45 | 9:10 PM Roma, Autostazione Tiburtina | 0 transfersDirect | |
FlixBus | 12:30 PM Assago, Viale Milanofiori (Assago M2) | 10h05 | 10:35 PM Roma, Autostazione Tiburtina | 0 transfersDirect | |
FlixBus | 12:40 PM Milano, Autostazione Lampugnano | 9h45 | 10:25 PM Roma, Autostazione Tiburtina | 0 transfersDirect | |
FlixBus | 12:45 PM Milano, San Donato - Settore B (Viale Giuseppe Impastato) | 7h35 | 8:20 PM Roma, Autostazione Tiburtina | 0 transfersDirect | |
3803 | 12:50 PM Milano, Autostazione Lampugnano | 8h20 | 9:10 PM Roma, Autostazione Tiburtina | 0 transfersDirect | |
Find all the dates and times for this journey
Compare prices and tickets Milan Centrale to Rome by train, bus, or flight
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
May 24
May 25
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May 31
Jun 01
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Why should you book Milan Centrale to Rome buses with Omio?
Why book with Omio vs FlixBus?
- Compare with other providers: On Omio, you can not only buy tickets for FlixBus, but also compare tickets for the likes of Itabus, Marino Autolinee, BlaBlaCar Bus or Autoservizi Salemi to find the best option for your trip from Milan Centrale to Rome.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare FlixBus with all available travel options, which are train, bus and flight to ensure you get the best deal for traveling from Milan Centrale to Rome.
Why book with Omio over Wanderu, Trainline or Checkmybus?
- Compare with other providers: On Omio, you can also compare tickets for the likes of Itabus, Marino Autolinee, BlaBlaCar Bus or Autoservizi Salemi to find the best option for your trip from Milan Centrale to Rome.
- Multiple modes of transport: Omio allows you to compare travel options including train, bus and flight to find the ideal travel option from Milan Centrale to Rome.
Journey information
Overview: Bus from Milan Centrale to Rome
Buses from Milan Centrale to Rome run on average 37 times per day, taking around 8h 11m. Cheap bus tickets for this journey start at €6 if you book in advance.
There are 28 buses per day. The earliest bus runs at 03:15, the last at 22:45. The fastest bus covers the 478 km distance in 7h 45m.
Distance 478 km |
Average bus duration 8h 11m |
Cheapest ticket price €6 |
Buses per day 37 |
Direct buses 28 |
Fastest bus 7h 45m |
First bus 3:15 AM |
Last bus 10:45 PM |
Cheapest Month Feb |
Cheapest Day Sat |
High Season Apr - Jun |
Low Season Jan - Mar |
Busiest Day Tue |
Least Busy Day Sat |
Bus providers: FlixBus, Itabus, BlaBlaCar, Marino Autolinee, BlaBlaCar Bus, Autoservizi Salemi, Infobus, ATM from Milan Centrale to RomeYou can travel by bus between Milan Centrale to Rome with FlixBus, Itabus, BlaBlaCar, Marino Autolinee, BlaBlaCar Bus, Autoservizi Salemi, Infobus, ATM for as low as €6. When you search for schedules and tickets, Omio will show you the best journey
FlixBus
Itabus
Marino Autolinee
Infobus
BlaBlaCar Bus
Autoservizi Salemi
BlaBlaCar
ATM
FAQs: Bus from Milan Centrale to Rome
Find answers to the most common questions about traveling from Milan Centrale to Rome by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Rome, this guide helps you travel smarter and with confidence.

- Marino Autolinee
- Assistance
- Priority seating
- Accessible restrooms.
- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
- Itabus
- Assistance
- Dedicated seating areas
- Accessible restrooms.
- Marino Autolinee
- You can cancel your ticket up to 24 hours before departure for a full refund. Cancellations within 24 hours incur a 50% fee.
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
- Itabus
- You can cancel your ticket up to 24 hours before departure for a partial refund. Changes allowed for a fee.
- Marino Autolinee
- One carry-on bag up to 10kg (55x40x20 cm) and one checked bag up to 20kg (80x50x30 cm).
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
- Itabus
- One carry-on bag up to 10kg and one checked bag up to 20kg.
- Marino Autolinee
- 10€ per additional bag up to 20 kg.
- FlixBus
- Additional luggage can be purchased for a fee.
- Itabus
- 5€ per additional bag.
- Marino Autolinee
- Small pets allowed in carriers
- larger pets must be leashed and muzzled.
- FlixBus
- Small pets in carriers allowed
- guide dogs travel for free.
- Itabus
- Small pets allowed in carriers
- larger pets must be leashed and muzzled.
popular bus stations
Popular bus stations from Milan Centrale to Rome
Most popular bus connections from Milan Centrale
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