The cheapest and fastest buses from Milan Centrale to Rome
Cheapest price
€7
Average price
€32
Fastest journey
5 h 50 m
Average duration
7 h 1 m
Buses per day
55
Distance
478 km
The best way to find a cheap bus ticket from Milan Centrale to Rome is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Milan Centrale to Rome will cost around €32 if you buy it on the day, but the cheapest tickets can be found for only €7.
Of the 55 buses that leave Milan Centrale for Rome on Sat, Nov 22, 40 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Sat, Nov 22 the direct buses cover the 478 km distance in an average of 7 h 1 m but if you time it right, some buses will get you there in just 5 h 50 m .
On Sat, Nov 22 the slowest buses will take 7 h 45 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
3803
FlixBus
3491
FlixBus
FlixBus

FlixBus
FlixBus
3491Travel Information
Compare train, bus, and flight for Milan Centrale to Rome
Omio recommends booking the train as it is the most popular option from Milan Centrale to Rome among Omio's users. If you are prioritising price take the bus with prices starting from €7. For those with little time consider booking a flight which can get you there in 1h 41m. The ticket price range depends on the travel mode: a bus costs an average of €7, and a flight costs an average of €56.
Distance: 478 km
Compare bus with
| Bus | Most popular Train | Flight |
|---|---|---|
€23 Average price Cheapest | €55 Average price | €165 Average price |
9h 4m Average total duration 8h 34m Onboard + 30m Additional time* | 6h 44m Average total duration 6h 14m Onboard + 30m Additional time* | 4h 41m Average total duration Fastest 1h 41m Onboard + 3h 0m Additional time* |
![]() Most popular bus company | ![]() Most popular train company | ![]() Most popular airline |
Direct Options | Direct Options | Direct Options |
Live departures
Milan Centrale to Rome bus times
The table below shows live departures for Milan Centrale to Rome buses for today, Friday, November 21. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
2809 · 2797 | 6:30 AM Milano, Autostazione Lampugnano | 12h10 | 6:40 PM Roma, Autostazione Tiburtina | 1 transfer | |
FlixBus · FlixBus | 6:55 AM Milano, Autostazione Lampugnano | 10h10 | 5:05 PM Roma, Autostazione (Metro Anagnina) | 1 transfer | |
FlixBus | 6:55 AM Milano, Autostazione Lampugnano | 8h35 | 3:30 PM Roma, Autostazione Tiburtina | 0 transfersDirect | |
FlixBus | 7:15 AM Milano, Autostazione Lampugnano | 10h20 | 5:35 PM Roma, Autostazione Tiburtina | 0 transfersDirect | |
FlixBus | 7:20 AM Milano, Autostazione Lampugnano | 9h30 | 4:50 PM Roma, Autostazione Tiburtina | 0 transfersDirect | |
FlixBus · FlixBus | 7:50 AM Milano, San Donato - Settore B (Viale Giuseppe Impastato) | 9h15 | 5:05 PM Roma, Autostazione (Metro Anagnina) | 1 transfer | |
FlixBus | 7:50 AM Milano, San Donato - Settore B (Viale Giuseppe Impastato) | 7h40 | 3:30 PM Roma, Autostazione Tiburtina | 0 transfersDirect | |
FlixBus | 8:05 AM Assago, Viale Milanofiori (Assago M2) | 8h45 | 4:50 PM Roma, Autostazione Tiburtina | 0 transfersDirect | |
3801 | 8:25 AM Milano, Autostazione Lampugnano | 8h20 | 4:45 PM Roma, Autostazione Tiburtina | 0 transfersDirect | |
FlixBus | 9:30 AM Milano, Autostazione Lampugnano | 8h15 | 5:45 PM Roma, Autostazione Tiburtina | 0 transfersDirect | |
2125 | 10:15 AM Milano, Autostazione Lampugnano | 8h00 | 6:15 PM Roma, Autostazione Tiburtina | 0 transfersDirect | |
FlixBus | 10:55 AM Milano, Autostazione Lampugnano | 8h25 | 7:20 PM Roma, Autostazione Tiburtina | 0 transfersDirect | |
FlixBus | 11:00 AM Milano, Autostazione Lampugnano | 10h35 | 9:35 PM Roma, Autostazione Tiburtina | 0 transfersDirect | |
FlixBus | 11:25 AM Milano, Autostazione Lampugnano | 8h45 | 8:10 PM Roma, Autostazione Tiburtina | 0 transfersDirect | |
FlixBus | 11:30 AM Assago, Viale Milanofiori (Assago M2) | 10h05 | 9:35 PM Roma, Autostazione Tiburtina | 0 transfersDirect | |
FlixBus | 11:45 AM Milano, San Donato - Settore B (Viale Giuseppe Impastato) | 7h35 | 7:20 PM Roma, Autostazione Tiburtina | 0 transfersDirect | |
FlixBus | 11:50 AM Milano, Autostazione Lampugnano | 9h30 | 9:20 PM Roma, Autostazione Tiburtina | 0 transfersDirect | |
3803 | 12:00 PM Milano, Autostazione Lampugnano | 8h10 | 8:10 PM Roma, Autostazione Tiburtina | 0 transfersDirect | |
FlixBus · FlixBus | 1:20 PM Sesto San Giovanni, Piazza Primo Maggio (Stazione ferroviaria) | 9h20 | 10:40 PM Roma, Autostazione Tiburtina | 1 transfer | |
FlixBus · FlixBus | 1:45 PM Milano, San Donato - Settore B (Viale Giuseppe Impastato) | 8h55 | 10:40 PM Roma, Autostazione Tiburtina | 1 transfer | |
110 | 2:10 PM Milano, Autostazione Lampugnano | 8h30 | 10:40 PM Roma, Autostazione Tiburtina | 0 transfersDirect | |
FlixBus | 2:15 PM Milano, Autostazione Lampugnano | 8h25 | 10:40 PM Roma, Autostazione Tiburtina | 0 transfersDirect | |
FlixBus | 2:50 PM Assago, Viale Milanofiori (Assago M2) | 7h50 | 10:40 PM Roma, Autostazione Tiburtina | 0 transfersDirect | |
3491 | 3:00 PM Milano, Autostazione Lampugnano | 7h45 | 10:45 PM Roma, Autostazione Tiburtina | 0 transfersDirect | |
FlixBus | 3:20 PM Milano, Autostazione Lampugnano | 8h50 | 12:10 AM Roma, Autostazione Tiburtina | 0 transfersDirect | |
FlixBus | 4:05 PM Milano, San Donato - Settore B (Viale Giuseppe Impastato) | 8h05 | 12:10 AM Roma, Autostazione Tiburtina | 0 transfersDirect | |
FlixBus · FlixBus | 5:25 PM Milano, Autostazione Lampugnano | 9h35 | 3:00 AM Roma, Autostazione Tiburtina | 1 transfer | |
FlixBus · FlixBus | 6:10 PM Milano, San Donato - Settore B (Viale Giuseppe Impastato) | 8h50 | 3:00 AM Roma, Autostazione Tiburtina | 1 transfer | |
2203 · 2413 | 6:25 PM Milano, Autostazione Lampugnano | 9h05 | 3:30 AM Roma, Autostazione Tiburtina | 1 transfer | |
2203 · 2421 | 6:25 PM Milano, Autostazione Lampugnano | 10h00 | 4:25 AM Roma, Autostazione Tiburtina | 1 transfer | |
055 | 7:25 PM Milano, Autostazione Lampugnano | 8h05 | 3:30 AM Roma, Autostazione Tiburtina | 0 transfersDirect | |
FlixBus | 7:30 PM Milano, Autostazione Lampugnano | 9h35 | 5:05 AM Roma, Autostazione (Metro Anagnina) | 0 transfersDirect | |
FlixBus | 7:30 PM Milano, Autostazione Lampugnano | 9h05 | 4:35 AM Roma, Autostazione Tiburtina | 0 transfersDirect | |
1801 | 7:50 PM Milano, Autostazione Lampugnano | 10h00 | 5:50 AM Roma, Autostazione Tiburtina | 0 transfersDirect | |
FlixBus | 8:00 PM Sesto San Giovanni, Piazza Primo Maggio (Stazione ferroviaria) | 9h05 | 5:05 AM Roma, Autostazione (Metro Anagnina) | 0 transfersDirect | |
FlixBus | 8:00 PM Sesto San Giovanni, Piazza Primo Maggio (Stazione ferroviaria) | 8h35 | 4:35 AM Roma, Autostazione Tiburtina | 0 transfersDirect | |
FlixBus · FlixBus | 8:20 PM Milano, San Donato - Settore B (Viale Giuseppe Impastato) | 8h50 | 5:10 AM Roma, Autostazione Tiburtina | 1 transfer | |
FlixBus | 9:00 PM Milano, Autostazione Lampugnano | 8h10 | 5:10 AM Roma, Autostazione Tiburtina | 0 transfersDirect | |
3897 | 9:30 PM Milano, Autostazione Lampugnano | 8h30 | 6:00 AM Roma, Autostazione Tiburtina | 0 transfersDirect | |
2495 | 9:40 PM Milano, Autostazione Lampugnano | 9h25 | 7:05 AM Roma, Autostazione Tiburtina | 0 transfersDirect | |
FlixBus | 9:45 PM Milano, Autostazione Lampugnano | 9h10 | 6:55 AM Roma, Autostazione Tiburtina | 0 transfersDirect | |
FlixBus | 9:45 PM Sesto San Giovanni, Piazza Primo Maggio (Stazione ferroviaria) | 11h45 | 9:30 AM Roma, Autostazione Tiburtina | 0 transfersDirect | |
FlixBus | 10:20 PM Milano, San Donato - Settore B (Viale Giuseppe Impastato) | 8h35 | 6:55 AM Roma, Autostazione Tiburtina | 0 transfersDirect | |
3825 | 10:55 PM Milano, Autostazione Lampugnano | 9h00 | 7:55 AM Roma, Autostazione Tiburtina | 0 transfersDirect | |
FlixBus | 11:30 PM Assago, Viale Milanofiori (Assago M2) | 10h00 | 9:30 AM Roma, Autostazione Tiburtina | 0 transfersDirect | |
FlixBus | 11:35 PM Milano, Autostazione Lampugnano | 8h05 | 7:40 AM Roma, Autostazione Tiburtina | 0 transfersDirect | |
| Saturday, November 22 | |||||
FlixBus | 12:10 AM Milano, San Donato - Settore B (Viale Giuseppe Impastato) | 7h30 | 7:40 AM Roma, Autostazione Tiburtina | 0 transfersDirect | |
FlixBus · FlixBus | 2:05 AM Milano, Autostazione Lampugnano | 10h15 | 12:20 PM Roma, Autostazione Tiburtina | 1 transfer | |
FlixBus | 4:15 AM Milano, Autostazione Lampugnano | 8h35 | 12:50 PM Roma, Autostazione Tiburtina | 0 transfersDirect | |
FlixBus · FlixBus | 4:35 AM Milano, Autostazione Lampugnano | 9h30 | 2:05 PM Roma, Autostazione (Metro Anagnina) | 1 transfer | |
2499 | 5:00 AM Milano, Autostazione Lampugnano | 9h00 | 2:00 PM Roma, Autostazione Tiburtina | 0 transfersDirect | |
FlixBus | 5:15 AM Milano, Autostazione Lampugnano | 9h05 | 2:20 PM Roma, Autostazione Tiburtina | 0 transfersDirect | |
FlixBus | 5:50 AM Milano, San Donato - Settore B (Viale Giuseppe Impastato) | 8h30 | 2:20 PM Roma, Autostazione Tiburtina | 0 transfersDirect | |
FlixBus · FlixBus | 6:15 AM Milano, Autostazione Lampugnano | 10h45 | 5:00 PM Roma, Autostazione (Metro Anagnina) | 1 transfer | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Milan Centrale to Rome by train, bus, or flight
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Journey information
Overview: Bus from Milan Centrale to Rome
Buses from Milan Centrale to Rome run on average 23 times per day, taking around 8h 34m. Cheap bus tickets for this journey start at €7 if you book in advance.
There are 18 buses per day. The earliest bus runs at 03:15, the last at 21:55. The fastest bus covers the 478 km distance in 7h 45m.
Distance 478 km |
Average bus duration 8h 34m |
Cheapest ticket price €7 |
Buses per day 23 |
Direct buses 18 |
Fastest bus 7h 45m |
First bus 03:15 |
Last bus 21:55 |
Bus providers: FlixBus, Itabus, BlaBlaCar, BlaBlaCar Bus, Infobus, Autoservizi Salemi, Marino Autolinee from Milan Centrale to RomeYou can travel by bus between Milan Centrale to Rome with FlixBus, Itabus, BlaBlaCar, BlaBlaCar Bus, Infobus, Autoservizi Salemi, Marino Autolinee for as low as €7. When you search for schedules and tickets, Omio will show you the best journey
FlixBus
Itabus
Infobus
Marino Autolinee
BlaBlaCar Bus
Autoservizi Salemi
BlaBlaCar
FAQs: Bus from Milan Centrale to Rome
Find answers to the most common questions about traveling from Milan Centrale to Rome by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Rome, this guide helps you travel smarter and with confidence.

To find the cheapest bus tickets for your trip from Milan Centrale to Rome, follow these tips:
Start your search now and compare ticket prices to find the best deal!
popular bus stations
Popular bus stations from Milan Centrale to Rome
- 06:00-23:00
- Free Wi-Fi
- Ristorante Italiano (in the station)
- Fast Food Express (in the station)
- Caffè del Terminal (in the station).
- Available outside the arrivals terminal.
- Elevators, ramps
- Available in the station.
- Bus: 520, 720 Train: Leonardo Express
Most popular bus connections from Milan Centrale
More options for your journey from Milan Centrale to Rome
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