The cheapest and fastest buses from Milan to Siena
Cheapest price
€9
Average price
€21
Fastest journey
3 h 40 m
Average duration
3 h 54 m
Buses per day
18
Distance
293 km
The best way to find a cheap bus ticket from Milan to Siena is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Milan to Siena will cost around €21 if you buy it on the day, but the cheapest tickets can be found for only €9.
Of the 18 buses that leave Milan for Siena on Wed, Nov 26, 17 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Wed, Nov 26 the direct buses cover the 293 km distance in an average of 3 h 54 m but if you time it right, some buses will get you there in just 3 h 40 m .
On Wed, Nov 26 the slowest buses will take 4 h 20 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
2401
FlixBus
2125 · 2401
2495
2499



FlixBusTravel Information
Compare bus, train, and flight for Milan to Siena
Omio recommends booking the bus as it is the most popular option from Milan to Siena among Omio's users. If you are prioritising price take the bus with prices starting from €8. For those with little time consider booking a train which can get you there in 4h 29m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.1 - 0.3kg. The ticket price range depends on the travel mode: a bus costs an average of €8, and a flight costs an average of €142.
Distance: 293 km
Compare bus with
Most popular Bus | Train | Flight |
|---|---|---|
€19 Average price Cheapest | €43 Average price | €217 Average price |
5h 42m Average total duration 5h 12m Onboard + 30m Additional time* | 4h 59m Average total duration Fastest 4h 29m Onboard + 30m Additional time* | 12h 52m Average total duration 9h 52m Onboard + 3h 0m Additional time* |
0.3 - 0.7kg CO2 emissions | 0.1 - 0.3kg CO2 emissions Lowest | - CO2 emissions |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Live departures
Milan to Siena bus times
The table below shows live departures for Milan to Siena buses for today, Tuesday, November 25. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
2499 | 5:00 AM Milano, Autostazione Lampugnano | 6h05 | 11:05 AM Siena, Stazione FS (Piazzale Carlo Rosselli) | 0 transfersDirect | |
2499 | 5:50 AM Milano, San Donato - Settore B (Viale Giuseppe Impastato) | 5h15 | 11:05 AM Siena, Stazione FS (Piazzale Carlo Rosselli) | 0 transfersDirect | |
FlixBus · FlixBus | 7:05 AM Milano, San Donato - Settore B (Viale Giuseppe Impastato) | 6h50 | 1:55 PM Siena, Stazione FS (Piazzale Carlo Rosselli) | 1 transfer | |
FlixBus | 7:15 AM Milano, Autostazione Lampugnano | 7h25 | 2:40 PM Siena, Stazione FS (Piazzale Carlo Rosselli) | 0 transfersDirect | |
FlixBus | 7:20 AM Milano, Autostazione Lampugnano | 6h35 | 1:55 PM Siena, Stazione FS (Piazzale Carlo Rosselli) | 0 transfersDirect | |
FlixBus · FlixBus | 9:10 AM Milano, Milan Linate Airport | 10h45 | 7:55 PM Siena, Stazione FS (Piazzale Carlo Rosselli) | 1 transfer | |
2125 · 2401 | 10:15 AM Milano, Autostazione Lampugnano | 7h30 | 5:45 PM Siena, Stazione FS (Piazzale Carlo Rosselli) | 1 transfer | |
FlixBus | 11:25 AM Milano, Autostazione Lampugnano | 5h50 | 5:15 PM Siena, Stazione FS (Piazzale Carlo Rosselli) | 0 transfersDirect | |
2401 | 12:25 PM Milano, San Donato - Settore B (Viale Giuseppe Impastato) | 5h20 | 5:45 PM Siena, Stazione FS (Piazzale Carlo Rosselli) | 0 transfersDirect | |
FlixBus | 2:30 PM Milano, Autostazione Lampugnano | 5h45 | 8:15 PM Siena, Stazione FS (Piazzale Carlo Rosselli) | 0 transfersDirect | |
FlixBus | 3:20 PM Milano, Autostazione Lampugnano | 6h00 | 9:20 PM Siena, Stazione FS (Piazzale Carlo Rosselli) | 0 transfersDirect | |
FlixBus | 4:05 PM Milano, San Donato - Settore B (Viale Giuseppe Impastato) | 5h15 | 9:20 PM Siena, Stazione FS (Piazzale Carlo Rosselli) | 0 transfersDirect | |
FlixBus · FlixBus | 9:00 PM Milano, Autostazione Lampugnano | 7h30 | 4:30 AM Siena, Stazione FS (Piazzale Carlo Rosselli) | 1 transfer | |
2495 | 9:40 PM Milano, Autostazione Lampugnano | 6h30 | 4:10 AM Siena, Stazione FS (Piazzale Carlo Rosselli) | 0 transfersDirect | |
2495 | 10:30 PM Milano, San Donato - Settore B (Viale Giuseppe Impastato) | 5h40 | 4:10 AM Siena, Stazione FS (Piazzale Carlo Rosselli) | 0 transfersDirect | |
3825 | 10:55 PM Milano, Autostazione Lampugnano | 6h05 | 5:00 AM Siena, Stazione FS (Piazzale Carlo Rosselli) | 0 transfersDirect | |
FlixBus | 11:35 PM Milano, Autostazione Lampugnano | 4h55 | 4:30 AM Siena, Stazione FS (Piazzale Carlo Rosselli) | 0 transfersDirect | |
3825 | 11:45 PM Milano, San Donato - Settore B (Viale Giuseppe Impastato) | 5h15 | 5:00 AM Siena, Stazione FS (Piazzale Carlo Rosselli) | 0 transfersDirect | |
| Wednesday, November 26 | |||||
FlixBus | 12:10 AM Milano, San Donato - Settore B (Viale Giuseppe Impastato) | 4h20 | 4:30 AM Siena, Stazione FS (Piazzale Carlo Rosselli) | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Milan to Siena by bus, train, or flight
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Journey information
Overview: Bus from Milan to Siena
Buses from Milan to Siena run on average 20 times per day, taking around 5h 12m. Cheap bus tickets for this journey start at €8 if you book in advance.
There are 17 buses per day. The earliest bus runs at 00:10, the last at 23:55. The fastest bus covers the 293 km distance in 5h 0m.
Distance 293 km |
Average bus duration 5h 12m |
Cheapest ticket price €8 |
Buses per day 20 |
Direct buses 17 |
Fastest bus 5h 0m |
First bus 00:10 |
Last bus 23:55 |
Bus providers: FlixBus, Itabus, BlaBlaCar from Milan to SienaYou can travel by bus between Milan to Siena with FlixBus, Itabus, BlaBlaCar for as low as €8. When you search for schedules and tickets, Omio will show you the best journey
FlixBus
Itabus
BlaBlaCar
FAQs: Bus from Milan to Siena
Find answers to the most common questions about traveling from Milan to Siena by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Siena, this guide helps you travel smarter and with confidence.

When departing from Milan, you have various coach station options to start your trip from including Milano, Milan Linate Airport, Milan, Stazione Garibaldi and Milan, Cadorna M1 M2 S R. When arriving in Siena, you can end your route in coach stations like Siena, Stazione FS, Siena, Via Fiorentina 135/Stellino and Siena, Siena/Viale Pietro Toselli.
Passengers board the coach most frequently from Milano, Milan Linate Airport, which is located around 5.5 miles (8.8 km) away from the city centre, and they get off the coach at Siena, Stazione FS, located 1.5 miles (2.4 km) away from the city centre.
popular bus stations
Popular bus stations from Milan to Siena
- 06:00-23:00
- Free Wi-Fi
- Cafeteria Milano (in the station)
- Trattoria San Donato (0.5 km)
- Burger House (0.7 km).
- Available outside the station.
- Elevators, ramps
- Available in the station.
- Metro: M3 Bus: 121, 132, 133
- 06:00-23:00
- Free Wi-Fi
- Cafeteria Lampugnano (in the station)
- Trattoria Milano (0.5 km)
- Pizza Express (0.7 km).
- Available outside the station.
- Elevators, ramps
- Available in the station.
- Metro: M1 Bus: 68, 78, 80
- 06:00-22:00
- Free Wi-Fi
- Cafeteria Italiana (in the station)
- Fast Food Express (in the station)
- Trattoria Milano (0.5 km).
- Available outside the station.
- Elevators, ramps
- Available in the station.
- Bus: 121, 132 Metro: M3
Most popular bus connections from Milan
More options for your journey from Milan to Siena
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