The cheapest and fastest buses from Milan to Siena
Cheapest price
€9
Average price
€18
Fastest journey
5 h
Average duration
5 h 15 m
Buses per day
22
Distance
293 km
The best way to find a cheap bus ticket from Milan to Siena is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Milan to Siena will cost around €18 if you buy it on the day, but the cheapest tickets can be found for only €9.
Of the 22 buses that leave Milan for Siena on Mon, May 25, 17 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Mon, May 25 the direct buses cover the 293 km distance in an average of 5 h 15 m but if you time it right, some buses will get you there in just 5 h .
On Mon, May 25 the slowest buses will take 5 h 40 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
212510:40 AM5h40Milano, Autostazione Lampugnano4:20 PMSiena, Stazione FS (Piazzale Carlo Rosselli)€91One-way0 transfers
240112:35 PM5h15Milano, San Donato - Settore B (Viale Giuseppe Impastato)5:50 PMSiena, Stazione FS (Piazzale Carlo Rosselli)€91One-way0 transfers
FlixBus12:00 PM7h40Milano, Autostazione Lampugnano7:40 PMSiena, Stazione FS (Piazzale Carlo Rosselli)€111One-way0 transfers
FlixBus6:15 AM6h15Milano, Autostazione Lampugnano12:30 PMSiena, Stazione FS (Piazzale Carlo Rosselli)€111One-way0 transfers
FlixBus2:45 PM5h05Milano, San Donato - Settore B (Viale Giuseppe Impastato)7:50 PMSiena, Stazione FS (Piazzale Carlo Rosselli)€111One-way0 transfers
FlixBus9:40 AM5h00Milano, San Donato - Settore B (Viale Giuseppe Impastato)2:40 PMSiena, Stazione FS (Piazzale Carlo Rosselli)€191One-way0 transfers
FlixBus2:45 PM5h05Milano, San Donato - Settore B (Viale Giuseppe Impastato)7:50 PMSiena, Stazione FS (Piazzale Carlo Rosselli)€111One-way0 transfers
FlixBus5:05 PM5h15Milano, San Donato - Settore B (Viale Giuseppe Impastato)10:20 PMSiena, Stazione FS (Piazzale Carlo Rosselli)€191One-way0 transfers
240112:35 PM5h15Milano, San Donato - Settore B (Viale Giuseppe Impastato)5:50 PMSiena, Stazione FS (Piazzale Carlo Rosselli)€91One-way0 transfers
212510:40 AM5h40Milano, Autostazione Lampugnano4:20 PMSiena, Stazione FS (Piazzale Carlo Rosselli)€91One-way0 transfers
Travel Information
Compare bus, train, and flight for Milan to Siena
Omio recommends booking the bus as it is the most popular option from Milan to Siena among Omio's users. If you are prioritising price take the bus with prices starting from €7. For those with little time consider booking a train which can get you there in 4h 38m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.1 - 0.3kg. The ticket price range depends on the travel mode: a bus costs an average of €7, and a flight costs an average of €137.
Distance: 293 km
Compare bus with
Most popular Bus | Train | Flight |
|---|---|---|
€14 Average price Cheapest | €43 Average price | €143 Average price |
5h 20m Average total duration 4h 50m Onboard + 30m Additional time* | 5h 8m Average total duration Fastest 4h 38m Onboard + 30m Additional time* | 12h 23m Average total duration 9h 23m Onboard + 3h 0m Additional time* |
0.3 - 0.7kg CO2 emissions | 0.1 - 0.3kg CO2 emissions Lowest | - CO2 emissions |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Live departures
Milan to Siena bus times
The table below shows live departures for Milan to Siena buses for today, Sunday, May 24. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
FlixBus · FlixBus | 9:10 PM Milano, San Donato - Settore B (Viale Giuseppe Impastato) | 8h20 | 5:30 AM Siena, Stazione FS (Piazzale Carlo Rosselli) | 1 transfer | |
FlixBus · FlixBus | 10:00 PM Milano, Autostazione Lampugnano | 7h30 | 5:30 AM Siena, Stazione FS (Piazzale Carlo Rosselli) | 1 transfer | |
2495 | 10:40 PM Milano, Autostazione Lampugnano | 6h30 | 5:10 AM Siena, Stazione FS (Piazzale Carlo Rosselli) | 0 transfersDirect | |
2495 | 11:30 PM Milano, San Donato - Settore B (Viale Giuseppe Impastato) | 5h40 | 5:10 AM Siena, Stazione FS (Piazzale Carlo Rosselli) | 0 transfersDirect | |
| Monday, May 25 | |||||
FlixBus | 5:35 AM Milano, Autostazione Lampugnano | 5h45 | 11:20 AM Siena, Stazione FS (Piazzale Carlo Rosselli) | 0 transfersDirect | |
FlixBus | 6:15 AM Milano, Autostazione Lampugnano | 6h15 | 12:30 PM Siena, Stazione FS (Piazzale Carlo Rosselli) | 0 transfersDirect | |
FlixBus | 6:50 AM Milano, San Donato - Settore B (Viale Giuseppe Impastato) | 5h40 | 12:30 PM Siena, Stazione FS (Piazzale Carlo Rosselli) | 0 transfersDirect | |
FlixBus · FlixBus | 8:00 AM Milano, San Donato - Settore B (Viale Giuseppe Impastato) | 6h20 | 2:20 PM Siena, Stazione FS (Piazzale Carlo Rosselli) | 1 transfer | |
FlixBus | 8:15 AM Milano, Autostazione Lampugnano | 7h25 | 3:40 PM Siena, Stazione FS (Piazzale Carlo Rosselli) | 0 transfersDirect | |
FlixBus | 8:20 AM Milano, Autostazione Lampugnano | 6h35 | 2:55 PM Siena, Stazione FS (Piazzale Carlo Rosselli) | 0 transfersDirect | |
3801 · 2125 | 8:55 AM Milano, Autostazione Lampugnano | 7h25 | 4:20 PM Siena, Stazione FS (Piazzale Carlo Rosselli) | 1 transfer | |
FlixBus | 9:40 AM Milano, San Donato - Settore B (Viale Giuseppe Impastato) | 5h00 | 2:40 PM Siena, Stazione FS (Piazzale Carlo Rosselli) | 0 transfersDirect | |
3801 · 2125 | 9:45 AM Milano, San Donato - Settore B (Viale Giuseppe Impastato) | 6h35 | 4:20 PM Siena, Stazione FS (Piazzale Carlo Rosselli) | 1 transfer | |
FlixBus · FlixBus | 10:20 AM Milano, Milan Linate Airport | 9h20 | 7:40 PM Siena, Stazione FS (Piazzale Carlo Rosselli) | 1 transfer | |
2125 | 10:40 AM Milano, Autostazione Lampugnano | 5h40 | 4:20 PM Siena, Stazione FS (Piazzale Carlo Rosselli) | 0 transfersDirect | |
FlixBus | 12:00 PM Milano, Autostazione Lampugnano | 7h40 | 7:40 PM Siena, Stazione FS (Piazzale Carlo Rosselli) | 0 transfersDirect | |
FlixBus | 12:25 PM Milano, Autostazione Lampugnano | 5h50 | 6:15 PM Siena, Stazione FS (Piazzale Carlo Rosselli) | 0 transfersDirect | |
2401 | 12:35 PM Milano, San Donato - Settore B (Viale Giuseppe Impastato) | 5h15 | 5:50 PM Siena, Stazione FS (Piazzale Carlo Rosselli) | 0 transfersDirect | |
FlixBus · FlixBus | 12:45 PM Milano, San Donato - Settore B (Viale Giuseppe Impastato) | 6h10 | 6:55 PM Siena, Stazione FS (Piazzale Carlo Rosselli) | 1 transfer | |
FlixBus | 2:45 PM Milano, San Donato - Settore B (Viale Giuseppe Impastato) | 5h05 | 7:50 PM Siena, Stazione FS (Piazzale Carlo Rosselli) | 0 transfersDirect | |
FlixBus | 3:30 PM Milano, Autostazione Lampugnano | 6h50 | 10:20 PM Siena, Stazione FS (Piazzale Carlo Rosselli) | 0 transfersDirect | |
FlixBus | 4:20 PM Milano, Autostazione Lampugnano | 6h00 | 10:20 PM Siena, Stazione FS (Piazzale Carlo Rosselli) | 0 transfersDirect | |
FlixBus | 4:30 PM Milano, San Donato - Settore B (Viale Giuseppe Impastato) | 5h50 | 10:20 PM Siena, Stazione FS (Piazzale Carlo Rosselli) | 0 transfersDirect | |
FlixBus | 5:05 PM Milano, San Donato - Settore B (Viale Giuseppe Impastato) | 5h15 | 10:20 PM Siena, Stazione FS (Piazzale Carlo Rosselli) | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Milan to Siena by bus, train, or flight
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Why should you book Milan to Siena buses with Omio?
Why book with Omio vs FlixBus?
- Compare with other providers: On Omio, you can not only buy tickets for FlixBus, but also compare tickets for the likes of Itabus to find the best option for your trip from Milan to Siena.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare FlixBus with all available travel options, which are bus, train and flight to ensure you get the best deal for traveling from Milan to Siena.
Why book with Omio over Wanderu, Trainline or Checkmybus?
- Compare with other providers: On Omio, you can also compare tickets for the likes of Itabus to find the best option for your trip from Milan to Siena.
- Multiple modes of transport: Omio allows you to compare travel options including bus, train and flight to find the ideal travel option from Milan to Siena.
Journey information
Overview: Bus from Milan to Siena
Buses from Milan to Siena run on average 21 times per day, taking around 4h 50m. Cheap bus tickets for this journey start at €7 if you book in advance.
There are 18 buses per day. The earliest bus runs at 00:10, the last at 23:55. The fastest bus covers the 293 km distance in 5h 15m.
Distance 293 km |
Average bus duration 4h 50m |
Cheapest ticket price €7 |
Buses per day 21 |
Direct buses 18 |
Fastest bus 5h 15m |
First bus 12:10 AM |
Last bus 11:55 PM |
Cheapest Month Feb |
Cheapest Day Sat |
High Season Apr - Jun |
Low Season Jan - Mar |
Busiest Day Wed |
Least Busy Day Thu |
Best time to book 21 days |
Bus providers: FlixBus, Itabus, BlaBlaCar from Milan to SienaYou can travel by bus between Milan to Siena with FlixBus, Itabus, BlaBlaCar for as low as €7. When you search for schedules and tickets, Omio will show you the best journey
FlixBus
Itabus
BlaBlaCar
FAQs: Bus from Milan to Siena
Find answers to the most common questions about traveling from Milan to Siena by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Siena, this guide helps you travel smarter and with confidence.

- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
- Itabus
- Assistance
- Dedicated seating areas
- Accessible restrooms.
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
- Itabus
- You can cancel your ticket up to 24 hours before departure for a partial refund. Changes allowed for a fee.
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
- Itabus
- One carry-on bag up to 10kg and one checked bag up to 20kg.
- FlixBus
- Additional luggage can be purchased for a fee.
- Itabus
- 5€ per additional bag.
- FlixBus
- Small pets in carriers allowed
- guide dogs travel for free.
- Itabus
- Small pets allowed in carriers
- larger pets must be leashed and muzzled.
popular bus stations
Popular bus stations from Milan to Siena
- 06:00-23:00
- Free Wi-Fi
- Cafeteria Lampugnano (in the station)
- Trattoria Milano (0.5 km)
- Pizza Express (0.7 km).
- Available outside the station.
- Elevators, ramps
- Available in the station.
- Metro: M1 Bus: 68, 78, 80
- 06:00-22:00
- Free Wi-Fi
- Cafeteria Italiana (in the station)
- Fast Food Express (in the station)
- Trattoria Milano (0.5 km).
- Available outside the station.
- Elevators, ramps
- Available in the station.
- Bus: 121, 132 Metro: M3
Most popular bus connections from Milan
More options for your journey from Milan to Siena
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