The cheapest and fastest buses from Milan to Brindisi
Cheapest price
€73
Average price
€125
Fastest journey
9 h 20 m
Average duration
10 h 58 m
Buses per day
40
Distance
890 km
The best way to find a cheap bus ticket from Milan to Brindisi is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Milan to Brindisi will cost around €125 if you buy it on the day, but the cheapest tickets can be found for only €73.
Of the 40 buses that leave Milan for Brindisi on Sun, Dec 21, 12 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Sun, Dec 21 the direct buses cover the 890 km distance in an average of 10 h 58 m but if you time it right, some buses will get you there in just 9 h 20 m .
On Sun, Dec 21 the slowest buses will take 12 h 40 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.


1801 · 1103
2421 · 1103
3897 · 1103



043Travel Information
Compare train, bus, and flight for Milan to Brindisi
Omio recommends booking the flight as it is the most popular option from Milan to Brindisi among Omio's users. If you are prioritising price take the bus with prices starting from €17. For those with little time consider booking a flight which can get you there in 1h 46m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.3 - 0.8kg. The ticket price range depends on the travel mode: a bus costs an average of €17, and a flight costs an average of €26.
Distance: 890 km
Compare bus with
| Bus | Most popular Flight | Train |
|---|---|---|
€50 Average price Cheapest | €107 Average price | €85 Average price |
13h 26m Average total duration 12h 56m Onboard + 30m Additional time* | 4h 46m Average total duration Fastest 1h 46m Onboard + 3h 0m Additional time* | 11h 31m Average total duration 11h 1m Onboard + 30m Additional time* |
0.9 - 2.2kg CO2 emissions | - CO2 emissions | 0.3 - 0.8kg CO2 emissions Lowest |
![]() Most popular bus company | ![]() Most popular airline | ![]() Most popular train company |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Live departures
Milan to Brindisi bus times
The table below shows live departures for Milan to Brindisi buses for today, Saturday, December 20. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
2499 · 1125 | 5:00 AM Milano, Autostazione Lampugnano | 17h25 | 10:25 PM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) | 1 transfer | |
2499 · 1125 | 5:50 AM Milano, San Donato - Settore B (Viale Giuseppe Impastato) | 16h35 | 10:25 PM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) | 1 transfer | |
FlixBus | 6:15 AM Milano, Autostazione Lampugnano | 14h25 | 8:40 PM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) | 0 transfersDirect | |
FlixBus | 7:05 AM Milano, San Donato - Settore B (Viale Giuseppe Impastato) | 13h35 | 8:40 PM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) | 0 transfersDirect | |
201 · 207 | 7:25 AM Milano, Autostazione Lampugnano | 13h45 | 9:10 PM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) | 1 transfer | |
201 · 207 | 8:10 AM Milano, San Donato - Settore B (Viale Giuseppe Impastato) | 13h00 | 9:10 PM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) | 1 transfer | |
FlixBus · FlixBus · FlixBus | 9:10 AM Milano, Milan Linate Airport | 20h00 | 5:10 AM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) | 2 transfers | |
FlixBus · FlixBus | 11:25 AM Milano, Autostazione Lampugnano | 17h45 | 5:10 AM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) | 1 transfer | |
FlixBus · FlixBus | 11:50 AM Milano, Autostazione Lampugnano | 18h25 | 6:15 AM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) | 1 transfer | |
3803 · 1107 | 12:00 PM Milano, Autostazione Lampugnano | 18h30 | 6:30 AM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) | 1 transfer | |
3803 · 1225 | 12:00 PM Milano, Autostazione Lampugnano | 19h30 | 7:30 AM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) | 1 transfer | |
2401 · 1107 | 12:25 PM Milano, San Donato - Settore B (Viale Giuseppe Impastato) | 18h05 | 6:30 AM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) | 1 transfer | |
2401 · 1225 | 12:25 PM Milano, San Donato - Settore B (Viale Giuseppe Impastato) | 19h05 | 7:30 AM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) | 1 transfer | |
FlixBus · FlixBus · FlixBus | 2:25 PM Milano, Milan Linate Airport | 18h40 | 9:05 AM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) | 2 transfers | |
FlixBus · FlixBus | 5:25 PM Milano, Autostazione Lampugnano | 15h40 | 9:05 AM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) | 1 transfer | |
FlixBus · FlixBus | 6:10 PM Milano, San Donato - Settore B (Viale Giuseppe Impastato) | 14h55 | 9:05 AM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) | 1 transfer | |
2203 | 6:25 PM Milano, Autostazione Lampugnano | 14h35 | 9:00 AM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) | 0 transfersDirect | |
FlixBus · FlixBus | 7:10 PM Milano, Autostazione Lampugnano | 13h55 | 9:05 AM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) | 1 transfer | |
FlixBus · FlixBus | 7:10 PM Milano, Autostazione Lampugnano | 14h20 | 9:30 AM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) | 1 transfer | |
2203 | 7:10 PM Milano, San Donato - Settore B (Viale Giuseppe Impastato) | 13h50 | 9:00 AM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) | 0 transfersDirect | |
FlixBus · FlixBus · FlixBus | 8:00 PM Milano, Milan Linate Airport | 19h45 | 3:45 PM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) | 2 transfers | |
FlixBus | 8:05 PM Milano, Autostazione Lampugnano | 14h15 | 10:20 AM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) | 0 transfersDirect | |
701 | 8:05 PM Milano, San Donato - Settore B (Viale Giuseppe Impastato) | 12h40 | 8:45 AM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) | 0 transfersDirect | |
2421 · 1103 | 8:35 PM Milano, San Donato - Settore B (Viale Giuseppe Impastato) | 19h00 | 3:35 PM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) | 1 transfer | |
FlixBus | 8:50 PM Milano, San Donato - Settore B (Viale Giuseppe Impastato) | 13h30 | 10:20 AM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) | 0 transfersDirect | |
3897 · 1103 | 9:30 PM Milano, Autostazione Lampugnano | 18h05 | 3:35 PM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) | 1 transfer | |
FlixBus · FlixBus | 9:45 PM Milano, Autostazione Lampugnano | 18h00 | 3:45 PM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) | 1 transfer | |
FlixBus · FlixBus | 10:20 PM Milano, San Donato - Settore B (Viale Giuseppe Impastato) | 17h25 | 3:45 PM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) | 1 transfer | |
FlixBus · FlixBus | 11:35 PM Milano, Autostazione Lampugnano | 17h50 | 5:25 PM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) | 1 transfer | |
| Sunday, December 21 | |||||
FlixBus · FlixBus | 12:10 AM Milano, San Donato - Settore B (Viale Giuseppe Impastato) | 17h15 | 5:25 PM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) | 1 transfer | |
Find all the dates and times for this journey
Compare prices and tickets Milan to Brindisi by train, bus, or flight
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Dec 20
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Journey information
Overview: Bus from Milan to Brindisi
Buses from Milan to Brindisi run on average 24 times per day, taking around 12h 56m. Cheap bus tickets for this journey start at €17 if you book in advance.
There are 6 buses per day. The earliest bus runs at 00:10, the last at 23:55. The fastest bus covers the 890 km distance in 10h 31m.
Distance 890 km |
Average bus duration 12h 56m |
Cheapest ticket price €17 |
Buses per day 24 |
Direct buses 6 |
Fastest bus 10h 31m |
First bus 00:10 |
Last bus 23:55 |
Bus providers: Marino Autolinee, Itabus, FlixBus, BlaBlaCar from Milan to BrindisiYou can travel by bus between Milan to Brindisi with Marino Autolinee, Itabus, FlixBus, BlaBlaCar for as low as €17. When you search for schedules and tickets, Omio will show you the best journey
Marino Autolinee
Itabus
FlixBus
BlaBlaCar
FAQs: Bus from Milan to Brindisi
Find answers to the most common questions about traveling from Milan to Brindisi by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Brindisi, this guide helps you travel smarter and with confidence.

When departing from Milan, you have various coach station options to start your trip from including Milano, Milan Linate Airport, Milan, Cadorna M1 M2 S R and Milan, Stazione Garibaldi. When arriving in Brindisi, you can end your route in coach stations like Brindisi, Aeroporto, Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) and Brindisi, Ospedale Antonio Perrino.
Passengers board the coach most frequently from Milano, Milan Linate Airport, which is located around 5.5 miles (8.8 km) away from the city centre, and they get off the coach at Brindisi, Aeroporto, located 3.1 miles (5 km) away from the city centre.
popular bus stations
Popular bus stations from Milan to Brindisi
- 06:00-23:00
- Free Wi-Fi
- Cafeteria Lampugnano (in the station)
- Trattoria Milano (0.5 km)
- Pizza Express (0.7 km).
- Available outside the station.
- Elevators, ramps
- Available in the station.
- Metro: M1 Bus: 68, 78, 80
- 06:00-22:00
- Free Wi-Fi
- Cafeteria Italiana (in the station)
- Fast Food Express (in the station)
- Trattoria Milano (0.5 km).
- Available outside the station.
- Elevators, ramps
- Available in the station.
- Bus: 121, 132 Metro: M3
Most popular bus connections from Milan
More options for your journey from Milan to Brindisi
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