The cheapest and fastest buses from Palermo to Syracuse
Cheapest price
€24
Average price
€24
Fastest journey
5 h 15 m
Average duration
5 h 15 m
Buses per day
1
Distance
204 km
The best way to find a cheap bus ticket from Palermo to Syracuse is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Palermo to Syracuse will cost around €24 if you buy it on the day, but the cheapest tickets can be found for only €24.
It's difficult to get from Palermo to Syracuse without transferring at least once.
FlixBus · FlixBus
FlixBus · FlixBusTravel Information
Compare bus and train for Palermo to Syracuse
Omio recommends booking the bus as it is the most popular option from Palermo to Syracuse among Omio's users. If you are prioritising price take the train with prices starting from €20. For those with little time consider booking a bus which can get you there in 4h 10m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.1 - 0.2kg. The ticket price range depends on the travel mode: a train costs an average of €20, and a bus costs an average of €14.
Distance: 204 km
Compare bus with
Most popular Bus | Train |
|---|---|
€27 Average price | €21 Average price Cheapest |
4h 40m Average total duration Fastest 4h 10m Onboard + 30m Additional time* | 5h 30m Average total duration 5h 0m Onboard + 30m Additional time* |
0.2 - 0.5kg CO2 emissions | 0.1 - 0.2kg CO2 emissions Lowest |
![]() Most popular bus company | ![]() Most popular train company |
Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Live departures
Palermo to Syracuse bus times
The table below shows live departures for Palermo to Syracuse buses for tomorrow, Sunday, March 1. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
FlixBus · FlixBus | 2:25 PM Palermo, Via Tommaso Fazello (Terminal Bus) | 5h15 | 7:40 PM Syracuse, Corso Umberto I | 1 transfer | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Palermo to Syracuse by bus or train
Compare bus and train prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Why should you book Palermo to Syracuse buses with Omio?
Why book with Omio vs Interbus S.p.A.?
- Compare with other providers: On Omio, you can not only buy tickets for Interbus S.p.A., but also compare tickets for the likes of European Sleeper, Infobus or FlixBus to find the best option for your trip from Palermo to Syracuse.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Interbus S.p.A. with all available travel options, which are bus and train to ensure you get the best deal for traveling from Palermo to Syracuse.
Why book with Omio over Checkmybus, Busbud or Wanderu?
- Compare with other providers: On Omio, you can also compare tickets for the likes of European Sleeper, Infobus or FlixBus to find the best option for your trip from Palermo to Syracuse.
- Multiple modes of transport: Omio allows you to compare travel options including bus and train to find the ideal travel option from Palermo to Syracuse.
Journey information
Overview: Bus from Palermo to Syracuse
Buses from Palermo to Syracuse run on average 5 times per day, taking around 4h 10m. Cheap bus tickets for this journey start at €14 if you book in advance.
There are 3 buses per day. The earliest bus runs at 04:20, the last at 20:05. The fastest bus covers the 204 km distance in 5h 5m.
Distance 204 km |
Average bus duration 4h 10m |
Cheapest ticket price €14 |
Buses per day 5 |
Direct buses 3 |
Fastest bus 5h 5m |
First bus 04:20 |
Last bus 20:05 |
Bus providers: Interbus S.p.A., European Sleeper, Infobus, FlixBus, BlaBlaCar from Palermo to SyracuseYou can travel by bus between Palermo to Syracuse with Interbus S.p.A., European Sleeper, Infobus, FlixBus, BlaBlaCar for as low as €14. When you search for schedules and tickets, Omio will show you the best journey
Infobus
FlixBus
Interbus S.p.A.
European Sleeper
BlaBlaCar
FAQs: Bus from Palermo to Syracuse
Find answers to the most common questions about traveling from Palermo to Syracuse by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Syracuse, this guide helps you travel smarter and with confidence.

- European Sleeper
- Pram/stroller access and dedicated wheelchair accessibility are available.
- Infobus
- Assistance
- Priority seating
- Transport for wheelchairs and mobility aids.
- Interbus S.p.A.
- Assistance
- Priority boarding
- Accessible seating.
- European Sleeper
- The cancellation policy depends on the type of ticket chosen.
- Infobus
- You can cancel your ticket up to 24 hours before departure for a partial refund. Cancellations within 24 hours may incur a fee.
- Interbus S.p.A.
- You can cancel your ticket up to 24 hours before departure for a 10% fee. No refunds for cancellations within 24 hours.
- European Sleeper
- One piece of baggage and one piece of hand luggage are allowed.
- Infobus
- One carry-on bag up to 5kg (40x20x25) and one checked bag up to 20kg (50x30x80).
- Interbus S.p.A.
- One carry-on bag up to 10kg (55x35x25) and one checked bag up to 20kg (70x50x30).
- European Sleeper
- For medium-sized dogs, an additional ticket is required.
- Infobus
- 10€ per additional bag.
- Interbus S.p.A.
- 10€ per additional bag up to 20 kg.
- European Sleeper
- Small pets are allowed in carriers, and dogs must be muzzled and leashed
- guide dogs are allowed for free.
- Infobus
- Small pets allowed in carriers
- larger pets may require a separate ticket.
- Interbus S.p.A.
- Small pets allowed in carriers
- larger pets may require a ticket and must be leashed and muzzled.
Most popular bus connections from Palermo
More options for your journey from Palermo to Syracuse
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