The cheapest and fastest buses from Syracuse to Palermo
Cheapest price
€26
Average price
€26
Fastest journey
7 h 10 m
Average duration
7 h 10 m
Buses per day
1
Distance
204 km
The best way to find a cheap bus ticket from Syracuse to Palermo is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Syracuse to Palermo will cost around €26 if you buy it on the day, but the cheapest tickets can be found for only €26.
Of the 1 buses that leave Syracuse for Palermo on Sat, Mar 21, 1 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Sat, Mar 21 the direct buses cover the 204 km distance in an average of 7 h 10 m but if you time it right, some buses will get you there in just 7 h 10 m .
On Sat, Mar 21 the slowest buses will take 7 h 10 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.


Travel Information
Compare bus and train for Syracuse to Palermo
Omio recommends booking the bus as it is the most popular option from Syracuse to Palermo among Omio's users. If you are prioritising price take the train with prices starting from €20. For those with little time consider booking a bus which can get you there in 3h 34m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.1 - 0.2kg. The ticket price range depends on the travel mode: a train costs an average of €20, and a bus costs an average of €16.
Distance: 204 km
Compare bus with
Most popular Bus | Train |
|---|---|
€27 Average price | €21 Average price Cheapest |
4h 4m Average total duration Fastest 3h 34m Onboard + 30m Additional time* | 5h 38m Average total duration 5h 8m Onboard + 30m Additional time* |
0.2 - 0.5kg CO2 emissions | 0.1 - 0.2kg CO2 emissions Lowest |
![]() Most popular bus company | ![]() Most popular train company |
Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Live departures
Syracuse to Palermo bus times
The table below shows live departures for Syracuse to Palermo buses for tomorrow, Friday, March 20. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 6:15 AM Syracuse | 7h10 | 1:25 PM Palermo | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Syracuse to Palermo by bus or train
Compare bus and train prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Mar 21
Mar 22
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Mar 26
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Apr 07
Apr 08
Apr 09
Apr 10
Why should you book Syracuse to Palermo buses with Omio?
Why book with Omio vs Interbus S.p.A.?
- Compare with other providers: On Omio, you can not only buy tickets for Interbus S.p.A., but also compare tickets for the likes of European Sleeper, Infobus or FlixBus to find the best option for your trip from Syracuse to Palermo.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Interbus S.p.A. with all available travel options, which are bus and train to ensure you get the best deal for traveling from Syracuse to Palermo.
Why book with Omio over Checkmybus, Busbud or Wanderu?
- Compare with other providers: On Omio, you can also compare tickets for the likes of European Sleeper, Infobus or FlixBus to find the best option for your trip from Syracuse to Palermo.
- Multiple modes of transport: Omio allows you to compare travel options including bus and train to find the ideal travel option from Syracuse to Palermo.
Journey information
Overview: Bus from Syracuse to Palermo
Buses from Syracuse to Palermo run on average 6 times per day, taking around 3h 34m. Cheap bus tickets for this journey start at €16 if you book in advance.
There are 3 buses per day. The earliest bus runs at 04:20, the last at 20:05. The fastest bus covers the 204 km distance in 6h 40m.
Distance 204 km |
Average bus duration 3h 34m |
Cheapest ticket price €16 |
Buses per day 6 |
Direct buses 3 |
Fastest bus 6h 40m |
First bus 04:20 |
Last bus 20:05 |
Bus providers: Interbus S.p.A., European Sleeper, Infobus, FlixBus, BlaBlaCar from Syracuse to PalermoYou can travel by bus between Syracuse to Palermo with Interbus S.p.A., European Sleeper, Infobus, FlixBus, BlaBlaCar for as low as €16. When you search for schedules and tickets, Omio will show you the best journey
Infobus
FlixBus
Interbus S.p.A.
European Sleeper
BlaBlaCar
FAQs: Bus from Syracuse to Palermo
Find answers to the most common questions about traveling from Syracuse to Palermo by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Palermo, this guide helps you travel smarter and with confidence.

- European Sleeper
- Pram/stroller access and dedicated wheelchair accessibility are available.
- Infobus
- Assistance
- Priority seating
- Transport for wheelchairs and mobility aids.
- Interbus S.p.A.
- Assistance
- Priority boarding
- Accessible seating.
- European Sleeper
- The cancellation policy depends on the type of ticket chosen.
- Infobus
- You can cancel your ticket up to 24 hours before departure for a partial refund. Cancellations within 24 hours may incur a fee.
- Interbus S.p.A.
- You can cancel your ticket up to 24 hours before departure for a 10% fee. No refunds for cancellations within 24 hours.
- European Sleeper
- One piece of baggage and one piece of hand luggage are allowed.
- Infobus
- One carry-on bag up to 5kg (40x20x25) and one checked bag up to 20kg (50x30x80).
- Interbus S.p.A.
- One carry-on bag up to 10kg (55x35x25) and one checked bag up to 20kg (70x50x30).
- European Sleeper
- For medium-sized dogs, an additional ticket is required.
- Infobus
- 10€ per additional bag.
- Interbus S.p.A.
- 10€ per additional bag up to 20 kg.
- European Sleeper
- Small pets are allowed in carriers, and dogs must be muzzled and leashed
- guide dogs are allowed for free.
- Infobus
- Small pets allowed in carriers
- larger pets may require a separate ticket.
- Interbus S.p.A.
- Small pets allowed in carriers
- larger pets may require a ticket and must be leashed and muzzled.
Most popular bus connections from Syracuse
More options for your journey from Syracuse to Palermo
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