The cheapest and fastest buses from Rome Termini to Siena
Cheapest price
€8
Average price
€12
Fastest journey
2 h 39 m
Average duration
2 h 40 m
Buses per day
22
Distance
185 km
The best way to find a cheap bus ticket from Rome Termini to Siena is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Rome Termini to Siena will cost around €12 if you buy it on the day, but the cheapest tickets can be found for only €8.
Of the 22 buses that leave Rome Termini for Siena on Fri, Feb 27, 22 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Fri, Feb 27 the direct buses cover the 185 km distance in an average of 2 h 40 m but if you time it right, some buses will get you there in just 2 h 39 m .
On Fri, Feb 27 the slowest buses will take 2 h 45 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
2494
FlixBus
2126
2704
FlixBus
FlixBus
FlixBus
FlixBus
FlixBus
FlixBusTravel Information
Compare train, bus, and flight for Rome Termini to Siena
Omio recommends booking the train as it is the most popular option from Rome Termini to Siena among Omio's users. If you are prioritising price take the bus with prices starting from €5. For those with little time consider booking a flight which can get you there in 55m. The ticket price range depends on the travel mode: a bus costs an average of €5, and a flight costs an average of €73.
Distance: 185 km
Compare bus with
| Bus | Most popular Train | Flight |
|---|---|---|
€9 Average price Cheapest | €21 Average price | €74 Average price |
3h 25m Average total duration 2h 55m Onboard + 30m Additional time* | 3h 50m Average total duration 3h 20m Onboard + 30m Additional time* | 3h 55m Average total duration Fastest 55m Onboard + 3h 0m Additional time* |
![]() Most popular bus company | ![]() Most popular train company | ![]() Most popular airline |
Direct Options | Direct Options | Direct Options |
Live departures
Rome Termini to Siena bus times
The table below shows live departures for Rome Termini to Siena buses for today, Thursday, February 26. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
FlixBus | 10:25 AM Roma, Autostazione Tiburtina | 2h55 | 1:20 PM Siena, Stazione FS (Piazzale Carlo Rosselli) | 0 transfersDirect | |
2704 | 11:00 AM Roma, Autostazione Tiburtina | 2h50 | 1:50 PM Siena, Stazione FS (Piazzale Carlo Rosselli) | 0 transfersDirect | |
FlixBus | 11:10 AM Roma, Autostazione Tiburtina | 2h40 | 1:50 PM Siena, Siena/Viale Pietro Toselli | 0 transfersDirect | |
FlixBus | 11:10 AM Roma, Autostazione Tiburtina | 2h50 | 2:00 PM Siena, Stazione FS (Piazzale Carlo Rosselli) | 0 transfersDirect | |
206 | 12:50 PM Roma, Autostazione Tiburtina | 3h00 | 3:50 PM Siena, Stazione FS (Piazzale Carlo Rosselli) | 0 transfersDirect | |
2726 | 1:00 PM Roma, Autostazione Tiburtina | 2h50 | 3:50 PM Siena, Stazione FS (Piazzale Carlo Rosselli) | 0 transfersDirect | |
FlixBus | 1:15 PM Roma, Autostazione Tiburtina | 2h39 | 3:54 PM Siena, Siena/Viale Pietro Toselli | 0 transfersDirect | |
FlixBus | 1:15 PM Roma, Autostazione Tiburtina | 2h45 | 4:00 PM Siena, Stazione FS (Piazzale Carlo Rosselli) | 0 transfersDirect | |
FlixBus | 1:15 PM Roma, Autostazione Tiburtina | 2h55 | 4:10 PM Siena, P.za Gramsc | 0 transfersDirect | |
2490 | 2:40 PM Roma, Autostazione Tiburtina | 2h50 | 5:30 PM Siena, Stazione FS (Piazzale Carlo Rosselli) | 0 transfersDirect | |
FlixBus | 2:45 PM Roma, Autostazione Tiburtina | 2h50 | 5:35 PM Siena, Stazione FS (Piazzale Carlo Rosselli) | 0 transfersDirect | |
FlixBus | 4:45 PM Roma, Autostazione Tiburtina | 2h39 | 7:24 PM Siena, Stazione FS (Piazzale Carlo Rosselli) | 0 transfersDirect | |
FlixBus | 6:10 PM Roma, Autostazione Tiburtina | 2h39 | 8:49 PM Siena, Siena/Viale Pietro Toselli | 0 transfersDirect | |
FlixBus | 6:10 PM Roma, Autostazione Tiburtina | 2h45 | 8:55 PM Siena, Stazione FS (Piazzale Carlo Rosselli) | 0 transfersDirect | |
FlixBus | 8:45 PM Roma, Autostazione Tiburtina | 2h55 | 11:40 PM Siena, Stazione FS (Piazzale Carlo Rosselli) | 0 transfersDirect | |
2494 | 9:15 PM Roma, Autostazione Tiburtina | 2h49 | 12:04 AM Siena, Stazione FS (Piazzale Carlo Rosselli) | 0 transfersDirect | |
| Friday, February 27 | |||||
107 | 4:35 AM Roma, Autostazione Tiburtina | 3h10 | 7:45 AM Siena, Stazione FS (Piazzale Carlo Rosselli) | 0 transfersDirect | |
FlixBus | 5:30 AM Roma, Autostazione Tiburtina | 2h45 | 8:15 AM Siena, Stazione FS (Piazzale Carlo Rosselli) | 0 transfersDirect | |
FlixBus | 6:45 AM Roma, Autostazione Tiburtina | 2h50 | 9:35 AM Siena, Stazione FS (Piazzale Carlo Rosselli) | 0 transfersDirect | |
2126 | 7:00 AM Roma, Autostazione Tiburtina | 2h50 | 9:50 AM Siena, Stazione FS (Piazzale Carlo Rosselli) | 0 transfersDirect | |
FlixBus | 7:30 AM Roma, Autostazione Tiburtina | 2h55 | 10:25 AM Siena, Stazione FS (Piazzale Carlo Rosselli) | 0 transfersDirect | |
FlixBus | 8:25 AM Roma, Autostazione Tiburtina | 2h45 | 11:10 AM Siena, Stazione FS (Piazzale Carlo Rosselli) | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Rome Termini to Siena by train, bus, or flight
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Why should you book Rome Termini to Siena buses with Omio?
Why book with Omio vs FlixBus?
- Compare with other providers: On Omio, you can not only buy tickets for FlixBus, but also compare tickets for the likes of Itabus, Marino Autolinee, Infobus or ATAC S.p.A. Azienda per la mobilità to find the best option for your trip from Rome Termini to Siena.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare FlixBus with all available travel options, which are train, bus and flight to ensure you get the best deal for traveling from Rome Termini to Siena.
Why book with Omio over Wanderu, Trainline or Checkmybus?
- Compare with other providers: On Omio, you can also compare tickets for the likes of Itabus, Marino Autolinee, Infobus or ATAC S.p.A. Azienda per la mobilità to find the best option for your trip from Rome Termini to Siena.
- Multiple modes of transport: Omio allows you to compare travel options including train, bus and flight to find the ideal travel option from Rome Termini to Siena.
Journey information
Overview: Bus from Rome Termini to Siena
Buses from Rome Termini to Siena run on average 24 times per day, taking around 2h 55m. Cheap bus tickets for this journey start at €5 if you book in advance.
There are 22 buses per day. The earliest bus runs at 05:30, the last at 21:15. The fastest bus covers the 185 km distance in 2h 39m.
Distance 185 km |
Average bus duration 2h 55m |
Cheapest ticket price €5 |
Buses per day 24 |
Direct buses 22 |
Fastest bus 2h 39m |
First bus 05:30 |
Last bus 21:15 |
Bus providers: FlixBus, Itabus, Marino Autolinee, BlaBlaCar, Infobus, ATAC S.p.A. Azienda per la mobilità from Rome Termini to SienaYou can travel by bus between Rome Termini to Siena with FlixBus, Itabus, Marino Autolinee, BlaBlaCar, Infobus, ATAC S.p.A. Azienda per la mobilità for as low as €5. When you search for schedules and tickets, Omio will show you the best journey
FlixBus
Itabus
Marino Autolinee
Infobus
BlaBlaCar
ATAC S.p.A. Azienda per la mobilità
FAQs: Bus from Rome Termini to Siena
Find answers to the most common questions about traveling from Rome Termini to Siena by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Siena, this guide helps you travel smarter and with confidence.

- Marino Autolinee
- Assistance
- Priority seating
- Accessible restrooms.
- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
- Itabus
- Assistance
- Dedicated seating areas
- Accessible restrooms.
- Marino Autolinee
- You can cancel your ticket up to 24 hours before departure for a full refund. Cancellations within 24 hours incur a 50% fee.
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
- Itabus
- You can cancel your ticket up to 24 hours before departure for a partial refund. Changes allowed for a fee.
- Marino Autolinee
- One carry-on bag up to 10kg (55x40x20 cm) and one checked bag up to 20kg (80x50x30 cm).
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
- Itabus
- One carry-on bag up to 10kg and one checked bag up to 20kg.
- Marino Autolinee
- 10€ per additional bag up to 20 kg.
- FlixBus
- Additional luggage can be purchased for a fee.
- Itabus
- 5€ per additional bag.
- Marino Autolinee
- Small pets allowed in carriers
- larger pets must be leashed and muzzled.
- FlixBus
- Small pets in carriers allowed
- guide dogs travel for free.
- Itabus
- Small pets allowed in carriers
- larger pets must be leashed and muzzled.
popular bus stations
Popular bus stations from Rome Termini to Siena
Most popular bus connections from Rome Termini
More options for your journey from Rome Termini to Siena
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