The cheapest and fastest buses from Frankfurt am Main to Prague
Cheapest price
€40
Average price
€52
Fastest journey
6 h 15 m
Average duration
6 h 36 m
Buses per day
38
Distance
409 km
The best way to find a cheap bus ticket from Frankfurt am Main to Prague is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Frankfurt am Main to Prague will cost around €52 if you buy it on the day, but the cheapest tickets can be found for only €40.
Of the 38 buses that leave Frankfurt am Main for Prague on Thu, May 28, 18 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Thu, May 28 the direct buses cover the 409 km distance in an average of 6 h 36 m but if you time it right, some buses will get you there in just 6 h 15 m .
On Thu, May 28 the slowest buses will take 6 h 56 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
(Amsterdam -> Prague)10:30 PM6h15Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof)4:45 AMPrague, Central Train Station€401One-way0 transfers
(Amsterdam -> Prague)10:00 PM6h48Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36)4:48 AMPraha, ÚAN Florenc€401One-way0 transfers
(Amsterdam -> Prague)10:00 PM6h45Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36)4:45 AMPrague, Central Train Station€401One-way0 transfers
(Amsterdam -> Prague)10:30 PM6h18Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof)4:48 AMPraha, ÚAN Florenc€401One-way0 transfers
FlixBus11:30 PM7h25Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36)6:55 AMPraha, ÚAN Florenc€421One-way0 transfers
(Amsterdam -> Prague)10:30 PM6h15Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof)4:45 AMPrague, Central Train Station€401One-way0 transfers
(Amsterdam -> Prague)10:30 PM6h18Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof)4:48 AMPraha, ÚAN Florenc€401One-way0 transfers
(Amsterdam -> Prague)10:00 PM6h45Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36)4:45 AMPrague, Central Train Station€401One-way0 transfers
(Amsterdam -> Prague)10:00 PM6h48Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36)4:48 AMPraha, ÚAN Florenc€401One-way0 transfers
FlixBus11:59 PM6h56Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof)6:55 AMPraha, ÚAN Florenc€481One-way0 transfers
Travel Information
Compare bus, train, and flight for Frankfurt am Main to Prague
Omio recommends booking the train as it is the most popular option from Frankfurt am Main to Prague among Omio's users. If you are prioritising price take the bus with prices starting from €13. For those with little time consider booking a flight which can get you there in 3h 19m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.1 - 0.4kg. The ticket price range depends on the travel mode: a bus costs an average of €13, and a flight costs an average of €144.
Distance: 409 km
Compare bus with
| Bus | Most popular Train | Flight |
|---|---|---|
€36 Average price Cheapest | €95 Average price | €228 Average price |
7h 36m Average total duration 7h 6m Onboard + 30m Additional time* | 6h 32m Average total duration 6h 2m Onboard + 30m Additional time* | 6h 19m Average total duration Fastest 3h 19m Onboard + 3h 0m Additional time* |
0.4 - 1.0kg CO2 emissions | 0.1 - 0.4kg CO2 emissions Lowest | 1.2 - 2.5kg CO2 emissions |
![]() Most popular bus company | ![]() Most popular train company | ![]() Most popular airline |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Live departures
Frankfurt am Main to Prague bus times
The table below shows live departures for Frankfurt am Main to Prague buses for today, Wednesday, May 27. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
FlixBus · FlixBus | 4:20 AM Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36) | 9h10 | 1:30 PM Praha, ÚAN Florenc | 1 transfer | |
FlixBus | 6:05 AM Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) | 7h25 | 1:30 PM Praha, ÚAN Florenc | 0 transfersDirect | |
FlixBus · FlixBus | 6:05 AM Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) | 9h55 | 4:00 PM Prague, Central Train Station | 1 transfer | |
FlixBus | 9:00 AM Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) | 8h55 | 5:55 PM Praha, ÚAN Florenc | 0 transfersDirect | |
FlixBus | 9:00 AM Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) | 8h35 | 5:35 PM Praha, M. Horákové (Hradčanská) | 0 transfersDirect | |
FlixTrain+ FlixBus | 9:58 AM Frankfurt South station | 10h02 | 8:00 PM Prague, Central Train Station | 1 transfer | |
FlixTrain+ FlixBus | 9:58 AM Frankfurt South station | 9h12 | 7:10 PM Praha, ÚAN Florenc | 1 transfer | |
FlixBus | 10:40 AM Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36) | 8h30 | 7:10 PM Praha, Na Knížecí | 0 transfersDirect | |
FlixBus | 10:40 AM Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36) | 8h55 | 7:35 PM Praha, ÚAN Florenc | 0 transfersDirect | |
FlixBus | 11:15 AM Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) | 7h55 | 7:10 PM Praha, Na Knížecí | 0 transfersDirect | |
FlixBus | 11:15 AM Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) | 8h20 | 7:35 PM Praha, ÚAN Florenc | 0 transfersDirect | |
FlixTrain+ FlixBus | 11:58 AM Frankfurt South station | 9h42 | 9:40 PM Praha, ÚAN Florenc | 1 transfer | |
FlixBus | 1:00 PM Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) | 8h10 | 9:10 PM Praha, Na Knížecí | 0 transfersDirect | |
FlixBus | 1:00 PM Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) | 8h30 | 9:30 PM Praha, ÚAN Florenc | 0 transfersDirect | |
FlixTrain+ FlixBus | 1:58 PM Frankfurt South station | 9h37 | 11:35 PM Praha, ÚAN Florenc | 1 transfer | |
FlixTrain+ FlixBus | 1:58 PM Frankfurt South station | 9h57 | 11:55 PM Prague, Central Train Station | 1 transfer | |
FlixBus | 3:20 PM Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) | 7h00 | 10:20 PM Praha, ÚAN Florenc | 0 transfersDirect | |
439п | 5:05 PM Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36) | 14h45 | 7:50 AM Praha, ÚAN Florenc | 0 transfersDirect | |
FlixBus | 5:05 PM Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) | 7h00 | 12:05 AM Praha, Na Knížecí | 0 transfersDirect | |
FlixBus | 5:05 PM Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) | 7h20 | 12:25 AM Prague, Central Train Station | 0 transfersDirect | |
439п | 5:30 PM Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) | 14h20 | 7:50 AM Praha, ÚAN Florenc | 0 transfersDirect | |
FlixBus · FlixBus | 10:00 PM Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) | 9h30 | 7:30 AM Praha, M. Horákové (Hradčanská) | 1 transfer | |
(Amsterdam -> Prague) | 10:00 PM Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36) | 6h45 | 4:45 AM Prague, Central Train Station | 0 transfersDirect | |
(Amsterdam -> Prague) | 10:00 PM Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36) | 6h48 | 4:48 AM Praha, ÚAN Florenc | 0 transfersDirect | |
(Amsterdam -> Prague) | 10:30 PM Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) | 6h15 | 4:45 AM Prague, Central Train Station | 0 transfersDirect | |
(Amsterdam -> Prague) | 10:30 PM Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) | 6h18 | 4:48 AM Praha, ÚAN Florenc | 0 transfersDirect | |
FlixBus | 11:30 PM Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36) | 7h25 | 6:55 AM Praha, ÚAN Florenc | 0 transfersDirect | |
FlixBus · FlixBus | 11:30 PM Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36) | 9h25 | 8:55 AM Praha, Na Knížecí | 1 transfer | |
FlixBus · FlixBus | 11:59 PM Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) | 8h56 | 8:55 AM Praha, Na Knížecí | 1 transfer | |
FlixBus | 11:59 PM Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) | 6h56 | 6:55 AM Praha, ÚAN Florenc | 0 transfersDirect | |
FlixBus · FlixBus | 1:15 AM Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36) | 8h50 | 10:05 AM Praha, Na Knížecí | 1 transfer | |
FlixBus · FlixBus | 1:15 AM Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36) | 10h15 | 11:30 AM Prague, Central Train Station | 1 transfer | |
FlixBus · FlixBus | 1:15 AM Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36) | 8h05 | 9:20 AM Praha, ÚAN Florenc | 1 transfer | |
FlixBus · FlixBus | 1:40 AM Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) | 9h50 | 11:30 AM Prague, Central Train Station | 1 transfer | |
FlixBus · FlixBus | 1:50 AM Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) | 8h15 | 10:05 AM Praha, Na Knížecí | 1 transfer | |
FlixBus · FlixBus | 1:50 AM Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) | 7h30 | 9:20 AM Praha, ÚAN Florenc | 1 transfer | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Frankfurt am Main to Prague by bus, train, or flight
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
May 27
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Jun 16
Why should you book Frankfurt am Main to Prague buses with Omio?
Why book with Omio vs FlixBus?
- Compare with other providers: On Omio, you can not only buy tickets for FlixBus, but also compare tickets for the likes of KLR, Infobus or BlaBlaCar Bus to find the best option for your trip from Frankfurt am Main to Prague.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare FlixBus with all available travel options, which are bus, train and flight to ensure you get the best deal for traveling from Frankfurt am Main to Prague.
Why book with Omio over Wanderu, Trainline or Checkmybus?
- Compare with other providers: On Omio, you can also compare tickets for the likes of KLR, Infobus or BlaBlaCar Bus to find the best option for your trip from Frankfurt am Main to Prague.
- Multiple modes of transport: Omio allows you to compare travel options including bus, train and flight to find the ideal travel option from Frankfurt am Main to Prague.
Journey information
Overview: Bus from Frankfurt am Main to Prague
Buses from Frankfurt am Main to Prague run on average 30 times per day, taking around 7h 6m. Cheap bus tickets for this journey start at €13 if you book in advance.
There are 14 buses per day. The earliest bus runs at 00:05, the last at 23:50. The fastest bus covers the 409 km distance in 6h 15m.
Distance 409 km |
Average bus duration 7h 6m |
Cheapest ticket price €13 |
Buses per day 30 |
Direct buses 14 |
Fastest bus 6h 15m |
First bus 12:05 AM |
Last bus 11:50 PM |
Cheapest Month Dec |
Cheapest Day Mon |
High Season Oct - Dec |
Low Season Jan - Mar |
Busiest Day Wed |
Least Busy Day Sat |
Best time to book 84 days |
Bus providers: FlixBus, KLR, Infobus, BlaBlaCar Bus, BlaBlaCar from Frankfurt am Main to PragueYou can travel by bus between Frankfurt am Main to Prague with FlixBus, KLR, Infobus, BlaBlaCar Bus, BlaBlaCar for as low as €13. When you search for schedules and tickets, Omio will show you the best journey
FlixBus
Infobus
BlaBlaCar Bus
KLR
BlaBlaCar
FAQs: Bus from Frankfurt am Main to Prague
Find answers to the most common questions about traveling from Frankfurt am Main to Prague by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Prague, this guide helps you travel smarter and with confidence.

- Infobus
- Assistance
- Priority seating
- Transport for wheelchairs and mobility aids.
- BlaBlaCar Bus
- Assistance
- Priority boarding
- Accessible seating options.
- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
- KLR
- No refunds are allowed
- changes can be made with a fee if done at least 96 hours before departure.
- Infobus
- You can cancel your ticket up to 24 hours before departure for a partial refund. Cancellations within 24 hours may incur a fee.
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
- KLR
- Each passenger is allowed one checked bag with a maximum weight of 20 kg and one personal bag free of charge.
- Infobus
- One carry-on bag up to 5kg (40x20x25) and one checked bag up to 20kg (50x30x80).
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
- KLR
- Additional luggage is subject to extra fees based on weight and size.
- Infobus
- 10€ per additional bag.
- FlixBus
- Additional luggage can be purchased for a fee.
- Infobus
- Small pets allowed in carriers
- larger pets may require a separate ticket.
- FlixBus
- Small pets in carriers allowed
- guide dogs travel for free.
popular bus stations
Popular bus stations from Frankfurt am Main to Prague
- 00:00-23:59
- Free Wi-Fi
- McDonald's (in the station)
- Hausmann's (in the station).
- Available outside the terminal at designated taxi stands.
- Elevators, ramps, assistance
- Available in the station.
- Bus: 61, 62, 77 Train: S8, S9
- 06:00-23:00
- Free Wi-Fi
- Cafeteria Florenc (in the station)
- Bistro Florenc (0.2 km)
- Restaurace U Rozvařilů (0.5 km).
- Available outside the main entrance.
- Elevators, ramps
- Available in the station.
- Bus: 133, 135, 175, 207 Metro: B, C
- 00:00-23:59
- Free Wi-Fi
- Czech Bistro (in the station)
- Fast Food Express (in the station)
- Bohemian Café (0.2 km).
- Available outside the main entrance.
- Elevators, ramps
- Available in the station.
- Bus: 135, 175, 207 Metro: C Train: All major s
- Free Wi-Fi
- Café Na Knížecí (in the station)
- Bistro Praha (0.2 km)
- Restaurace U Knížete (0.5 km).
- Available outside the main entrance.
- Elevators, ramps
- Available in the station.
- Bus: 137, 176, 191 Metro: B
Most popular bus connections from Frankfurt am Main
More options for your journey from Frankfurt am Main to Prague
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