The cheapest and fastest buses from Siena to Milan
Cheapest price on Sep 17
€11
Average ticket price on Sep 17
€18
Fastest journey on Sep 17
4 h 30 m
Average journey duration on Sep 17
4 h 55 m
Buses on Sep 17
18
Distance
293 km
The best way to find a cheap bus ticket from Siena to Milan is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Siena to Milan will cost around €18 if you buy it on the day, but the cheapest tickets can be found for only €11.
On Thu, Sep 17, we found 18 buses from Siena to Milan, including 17 direct services.
On Thu, Sep 17 the direct buses cover the 293 km distance in an average of 4 h 55 m but if you time it right, some buses will get you there in just 4 h 30 m .
On Thu, Sep 17 the slowest buses will take 5 h 10 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
24005:55 PM5h10Siena, Stazione FS (Piazzale Carlo Rosselli)11:05 PMMilano, San Donato - Settore B (Viale Giuseppe Impastato)€111One-way0 transfers
FlixBus4:05 PM4h50Siena, Stazione FS (Piazzale Carlo Rosselli)8:55 PMMilano, San Donato - Settore B (Viale Giuseppe Impastato)€131One-way0 transfers
24021:55 PM4h55Siena, Stazione FS (Piazzale Carlo Rosselli)6:50 PMMilano, San Donato - Settore B (Viale Giuseppe Impastato)€131One-way0 transfers
FlixBus12:15 PM5h40Siena, Stazione FS (Piazzale Carlo Rosselli)5:55 PMMilano, Autostazione Lampugnano€131One-way0 transfers
FlixBus6:40 PM5h19Siena, Stazione FS (Piazzale Carlo Rosselli)11:59 PMMilano, Autostazione Lampugnano€141One-way0 transfers
FlixBus12:45 AM4h30Siena, Stazione FS (Piazzale Carlo Rosselli)5:15 AMMilano, San Donato - Settore B (Viale Giuseppe Impastato)€241One-way0 transfers
FlixBus4:05 PM4h50Siena, Stazione FS (Piazzale Carlo Rosselli)8:55 PMMilano, San Donato - Settore B (Viale Giuseppe Impastato)€131One-way0 transfers
24021:55 PM4h55Siena, Stazione FS (Piazzale Carlo Rosselli)6:50 PMMilano, San Donato - Settore B (Viale Giuseppe Impastato)€131One-way0 transfers
FlixBus12:45 AM5h10Siena, Stazione FS (Piazzale Carlo Rosselli)5:55 AMMilano, Autostazione Lampugnano€241One-way0 transfers
24005:55 PM5h10Siena, Stazione FS (Piazzale Carlo Rosselli)11:05 PMMilano, San Donato - Settore B (Viale Giuseppe Impastato)€111One-way0 transfers
Travel Information
Compare bus and train for Siena to Milan
Omio recommends booking the bus as it is the most popular option from Siena to Milan among Omio's users. If you are prioritising price, take the bus, with an average ticket price of €12 For those with little time, consider booking a train, which has an average total journey time of 4h 31m. If you are seeking to minimise your carbon footprint, the train is your best option, with estimated CO2 emissions of 0.1 - 0.3kg. Average ticket prices depend on the travel mode: a bus costs an average of €12, while a train costs an average of €31.
Distance: 293 km
Compare bus with
Most popular Bus | Train |
|---|---|
€12 Average price Cheapest | €31 Average price |
6h 20m Average total duration 5h 50m Onboard + 30m Additional time* | 4h 31m Average total duration Fastest 4h 1m Onboard + 30m Additional time* |
0.3 - 0.7kg CO2 emissions | 0.1 - 0.3kg CO2 emissions Lowest |
![]() Most popular bus company | ![]() Most popular train company |
Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
This is compared to other travel options from Siena to Milan:
A bus is €19 less than a train for this route with tickets for a train from Siena to Milan costing on average €31.
Other travel options to Milan take longer:
Bus takes on average 5h 50m.
Live departures
Siena to Milan bus times
The table below shows live departures for Siena to Milan buses for tomorrow, Thursday, September 17. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
FlixBus | 12:45 AM Siena, Stazione FS (Piazzale Carlo Rosselli) | 5h10 | 5:55 AM Milano, Autostazione Lampugnano | 0 transfersDirect | |
FlixBus | 12:45 AM Siena, Stazione FS (Piazzale Carlo Rosselli) | 4h30 | 5:15 AM Milano, San Donato - Settore B (Viale Giuseppe Impastato) | 0 transfersDirect | |
2494 | 1:05 AM Siena, Stazione FS (Piazzale Carlo Rosselli) | 5h50 | 6:55 AM Milano, Autostazione Lampugnano | 0 transfersDirect | |
FlixBus | 6:10 AM Siena, Stazione FS (Piazzale Carlo Rosselli) | 6h50 | 1:00 PM Milano, Autostazione Lampugnano | 0 transfersDirect | |
FlixBus | 6:10 AM Siena, Stazione FS (Piazzale Carlo Rosselli) | 5h50 | 12:00 PM Milano, San Donato - Settore B (Viale Giuseppe Impastato) | 0 transfersDirect | |
FlixBus | 7:50 AM Siena, Stazione FS (Piazzale Carlo Rosselli) | 5h55 | 1:45 PM Milano, Autostazione Lampugnano | 0 transfersDirect | |
FlixBus | 9:20 AM Siena, Stazione FS (Piazzale Carlo Rosselli) | 5h15 | 2:35 PM Milano, San Donato - Settore B (Viale Giuseppe Impastato) | 0 transfersDirect | |
FlixBus | 9:20 AM Siena, Stazione FS (Piazzale Carlo Rosselli) | 6h00 | 3:20 PM Milano, Autostazione Lampugnano | 0 transfersDirect | |
FlixBus | 11:30 AM Siena, Stazione FS (Piazzale Carlo Rosselli) | 7h25 | 6:55 PM Milano, Autostazione Lampugnano | 0 transfersDirect | |
FlixBus | 12:15 PM Siena, Stazione FS (Piazzale Carlo Rosselli) | 5h40 | 5:55 PM Milano, Autostazione Lampugnano | 0 transfersDirect | |
2402 | 1:55 PM Siena, Stazione FS (Piazzale Carlo Rosselli) | 4h55 | 6:50 PM Milano, San Donato - Settore B (Viale Giuseppe Impastato) | 0 transfersDirect | |
FlixBus | 2:25 PM Siena, Stazione FS (Piazzale Carlo Rosselli) | 7h20 | 9:45 PM Milano, Autostazione Lampugnano | 0 transfersDirect | |
FlixBus | 2:51 PM Siena, Siena/Viale Pietro Toselli | 6h49 | 9:40 PM Milano, Autostazione Lampugnano | 0 transfersDirect | |
FlixBus · FlixBus | 2:51 PM Siena, Siena/Viale Pietro Toselli | 6h04 | 8:55 PM Milano, San Donato - Settore B (Viale Giuseppe Impastato) | 1 transfer | |
FlixBus | 3:05 PM Siena, Stazione FS (Piazzale Carlo Rosselli) | 6h35 | 9:40 PM Milano, Autostazione Lampugnano | 0 transfersDirect | |
FlixBus | 4:05 PM Siena, Stazione FS (Piazzale Carlo Rosselli) | 4h50 | 8:55 PM Milano, San Donato - Settore B (Viale Giuseppe Impastato) | 0 transfersDirect | |
2400 | 5:55 PM Siena, Stazione FS (Piazzale Carlo Rosselli) | 5h10 | 11:05 PM Milano, San Donato - Settore B (Viale Giuseppe Impastato) | 0 transfersDirect | |
FlixBus | 6:40 PM Siena, Stazione FS (Piazzale Carlo Rosselli) | 5h19 | 11:59 PM Milano, Autostazione Lampugnano | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Siena to Milan by bus or train
Compare bus and train prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Sep 17
Sep 18
Sep 19
Sep 20
Sep 21
Sep 22
Sep 23
Sep 24
Sep 25
Sep 26
Sep 27
Sep 28
Sep 29
Sep 30
Oct 01
Oct 02
Oct 03
Oct 04
Oct 05
Oct 06
Oct 07
Why should you book Siena to Milan buses with Omio?
Why book with Omio vs FlixBus?
- Compare with other providers: On Omio, you can not only buy tickets for FlixBus, but also compare tickets for the likes of Itabus to find the best option for your trip from Siena to Milan.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare FlixBus with all available travel options, which are bus and train to ensure you get the best deal for traveling from Siena to Milan.
Why book with Omio over Wanderu, Trainline or Checkmybus?
- Compare with other providers: On Omio, you can also compare tickets for the likes of Itabus to find the best option for your trip from Siena to Milan.
- Multiple modes of transport: Omio allows you to compare travel options including bus and train to find the ideal travel option from Siena to Milan.
Journey information
Overview: Bus from Siena to Milan
Buses from Siena to Milan run on average 23 times per day, taking around 5h 50m. Cheap bus tickets for this journey start at €7 if you book in advance.
There are 18 buses per day. The earliest bus runs at 00:10, the last at 23:55. The fastest bus covers the 293 km distance in 4h 50m.
Distance 293 km |
Average bus duration 5h 50m |
Cheapest ticket price €7 |
Buses per day 23 |
Direct buses 18 |
Fastest bus 4h 50m |
First bus 12:10 AM |
Last bus 11:55 PM |
Cheapest Month Dec |
Cheapest Day Sat |
High Season Oct - Dec |
Low Season Jan - Mar |
Busiest Day Thu |
Least Busy Day Sun |
Best time to book 6 days |
Bus providers: FlixBus, Itabus, BlaBlaCar from Siena to MilanYou can travel by bus between Siena to Milan with FlixBus, Itabus, BlaBlaCar for as low as €7. When you search for schedules and tickets, Omio will show you the best journey
FlixBus
Itabus
BlaBlaCar
FAQs: Bus from Siena to Milan
Find answers to the most common questions about traveling from Siena to Milan by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Milan, this guide helps you travel smarter and with confidence.

- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
- Itabus
- Assistance
- Dedicated seating areas
- Accessible restrooms.
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
- Itabus
- You can cancel your ticket up to 24 hours before departure for a partial refund. Changes allowed for a fee.
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
- Itabus
- One carry-on bag up to 10kg and one checked bag up to 20kg.
- FlixBus
- Additional luggage can be purchased for a fee.
- Itabus
- 5€ per additional bag.
- FlixBus
- Small pets in carriers allowed
- guide dogs travel for free.
- Itabus
- Small pets allowed in carriers
- larger pets must be leashed and muzzled.
popular bus stations
Popular bus stations from Siena to Milan
Most Siena to Milan buses use the Siena, Stazione FS (Piazzale Carlo Rosselli) to Milano, Autostazione Lampugnano station pair, with some services arriving at Milano, San Donato - Settore B (Viale Giuseppe Impastato). Use this guide to compare Siena and Milan bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Which Siena station do buses to Milan leave from?
Getting to Siena, Stazione FS (Piazzale Carlo Rosselli) from Siena city centre
Siena, Stazione FS (Piazzale Carlo Rosselli) is 1 km from Siena city centre. Public transport options include:
Siena, Stazione FS (Piazzale Carlo Rosselli) bus station facilities and services
Siena, Stazione FS (Piazzale Carlo Rosselli) has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food and drink
Food options include: Cafeteria and vending machines available.
Wi-Fi and ATMs
Wi-Fi is available at Siena, Stazione FS (Piazzale Carlo Rosselli). ATMs are available at Siena, Stazione FS (Piazzale Carlo Rosselli).
Tickets and information
Ticket office support is available at Siena, Stazione FS (Piazzale Carlo Rosselli).
Parking, taxis and toilets
Available at Siena, Stazione FS (Piazzale Carlo Rosselli): Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Siena, Stazione FS (Piazzale Carlo Rosselli): Wheelchair ramps are provided.
Getting to Siena, Siena/Viale Pietro Toselli from Siena city centre
Siena, Siena/Viale Pietro Toselli is 1 km from Siena city centre. Public transport options include:
Siena, Siena/Viale Pietro Toselli bus station facilities and services
Siena, Siena/Viale Pietro Toselli has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food and drink
Food options include: Nearby cafes and fast food available.
Wi-Fi and ATMs
Wi-Fi is available at Siena, Siena/Viale Pietro Toselli. ATMs are available at Siena, Siena/Viale Pietro Toselli.
Tickets and information
Ticket office support is available at Siena, Siena/Viale Pietro Toselli.
Parking, taxis and toilets
Available at Siena, Siena/Viale Pietro Toselli: Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Siena, Siena/Viale Pietro Toselli: Ramps and accessible paths available.
Getting to Siena, P.za Gramsc from Siena city centre
Siena, P.za Gramsc bus station facilities and services
Siena, P.za Gramsc has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi and ATMs
Wi-Fi is available at Siena, P.za Gramsc. ATMs are available at Siena, P.za Gramsc.
Tickets and information
Ticket office support is available at Siena, P.za Gramsc.
Parking, taxis and toilets
Available at Siena, P.za Gramsc: Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Siena, P.za Gramsc: The station is accessible with ramps and lowered curbs.
Which Milan station do buses from Siena arrive at?
Getting to Milano, Autostazione Lampugnano from Milan city centre
Milano, Autostazione Lampugnano is 5 km from Milan city centre. Public transport options include:
Milano, Autostazione Lampugnano bus station facilities and services
Milano, Autostazione Lampugnano has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, and Ticket Office.
Food and drink
Food options include: Cafeteria Lampugnano (in the station), Trattoria Milano (0.5 km), Pizza Express (0.7 km).
Wi-Fi and ATMs
Free Wi-Fi. ATMs are located near the main entrance.
Tickets and information
Ticket office support is available at Milano, Autostazione Lampugnano.
Parking, taxis and toilets
Available at Milano, Autostazione Lampugnano: Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Milano, Autostazione Lampugnano: Elevators, ramps.
Getting to Milano, San Donato - Settore B (Viale Giuseppe Impastato) from Milan city centre
Milano, San Donato - Settore B (Viale Giuseppe Impastato) is 6 km from Milan city centre. Public transport options include:
Milano, San Donato - Settore B (Viale Giuseppe Impastato) bus station facilities and services
Milano, San Donato - Settore B (Viale Giuseppe Impastato) has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, and Ticket Office.
Food and drink
Food options include: Cafeteria Italiana (in the station), Fast Food Express (in the station), Trattoria Milano (0.5 km).
Wi-Fi and ATMs
Free Wi-Fi. ATMs are located near the main entrance for cash withdrawals.
Tickets and information
Ticket office support is available at Milano, San Donato - Settore B (Viale Giuseppe Impastato).
Parking, taxis and toilets
Available at Milano, San Donato - Settore B (Viale Giuseppe Impastato): Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Milano, San Donato - Settore B (Viale Giuseppe Impastato): Elevators, ramps.
Getting to Milano, Aeroporto di Milano Linate from Milan city centre
Most popular bus connections from Siena
More options for your journey from Siena to Milan
Here are some other resources that might have the information you need

