The cheapest and fastest buses from Siena to Milan
Cheapest price
€20
Average price
€46
Fastest journey
3 h 10 m
Average duration
3 h 54 m
Buses per day
20
Distance
293 km
The best way to find a cheap bus ticket from Siena to Milan is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Siena to Milan will cost around €46 if you buy it on the day, but the cheapest tickets can be found for only €20.
Of the 20 buses that leave Siena for Milan on Wed, Nov 05, 14 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Wed, Nov 05 the direct buses cover the 293 km distance in an average of 3 h 54 m but if you time it right, some buses will get you there in just 3 h 10 m .
On Wed, Nov 05 the slowest buses will take 4 h 30 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
2490
2490







Travel Information
Compare train, bus, and flight for Siena to Milan
Omio recommends booking the bus as it is the most popular option from Siena to Milan among Omio's users. If you are prioritising price take the bus with prices starting from €8. For those with little time consider booking a train which can get you there in 4h 2m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.1 - 0.3kg. The ticket price range depends on the travel mode: a bus costs an average of €8, and a flight costs an average of €103.
Distance: 293 km
Compare bus with
Most popular Bus | Train | Flight |
|---|---|---|
€21 Average price Cheapest | €42 Average price | €174 Average price |
6h 24m Average total duration 5h 54m Onboard + 30m Additional time* | 4h 32m Average total duration Fastest 4h 2m Onboard + 30m Additional time* | 11h 49m Average total duration 8h 49m Onboard + 3h 0m Additional time* |
0.3 - 0.7kg CO2 emissions | 0.1 - 0.3kg CO2 emissions Lowest | - CO2 emissions |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Live departures
Siena to Milan bus times
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
FlixBus | 11:45 PM Siena, Stazione FS (Piazzale Carlo Rosselli) | 4h30 | 4:15 AM Milano, San Donato - Settore B (Viale Giuseppe Impastato) | 0 transfersDirect | |
FlixBus | 11:45 PM Siena, Stazione FS (Piazzale Carlo Rosselli) | 5h10 | 4:55 AM Milano, Autostazione Lampugnano | 0 transfersDirect | |
| Wednesday, November 5 | |||||
3825 · 2402 | 5:05 AM Siena, Stazione FS (Piazzale Carlo Rosselli) | 13h10 | 6:15 PM Milano, San Donato - Settore B (Viale Giuseppe Impastato) | 1 transfer | |
FlixBus | 5:10 AM Siena, Stazione FS (Piazzale Carlo Rosselli) | 5h45 | 10:55 AM Milano, Autostazione Lampugnano | 0 transfersDirect | |
FlixBus | 6:50 AM Siena, Stazione FS (Piazzale Carlo Rosselli) | 5h50 | 12:40 PM Milano, Autostazione Lampugnano | 0 transfersDirect | |
FlixBus | 11:15 AM Siena, Stazione FS (Piazzale Carlo Rosselli) | 5h40 | 4:55 PM Milano, Autostazione Lampugnano | 0 transfersDirect | |
FlixBus | 1:51 PM Siena, Siena/Viale Pietro Toselli | 6h49 | 8:40 PM Milano, Autostazione Lampugnano | 0 transfersDirect | |
FlixBus | 2:05 PM Siena, Stazione FS (Piazzale Carlo Rosselli) | 6h35 | 8:40 PM Milano, Autostazione Lampugnano | 0 transfersDirect | |
2490 | 5:35 PM Siena, Stazione FS (Piazzale Carlo Rosselli) | 6h00 | 11:35 PM Milano, Autostazione Lampugnano | 0 transfersDirect | |
2490 | 5:35 PM Siena, Stazione FS (Piazzale Carlo Rosselli) | 5h14 | 10:49 PM Milano, San Donato - Settore B (Viale Giuseppe Impastato) | 0 transfersDirect | |
2401 · 3826 | 5:50 PM Siena, Stazione FS (Piazzale Carlo Rosselli) | 12h45 | 6:35 AM Milano, Autostazione Lampugnano | 1 transfer | |
2401 · 3826 | 5:50 PM Siena, Stazione FS (Piazzale Carlo Rosselli) | 12h00 | 5:50 AM Milano, San Donato - Settore B (Viale Giuseppe Impastato) | 1 transfer | |
2401 · 2422 | 5:50 PM Siena, Stazione FS (Piazzale Carlo Rosselli) | 12h45 | 6:35 AM Milano, San Donato - Settore B (Viale Giuseppe Impastato) | 1 transfer | |
FlixBus · FlixBus | 8:45 PM Siena, Siena/Viale Pietro Toselli | 6h15 | 3:00 AM Milano, Autostazione Lampugnano | 1 transfer | |
FlixBus · FlixBus | 8:55 PM Siena, Stazione FS (Piazzale Carlo Rosselli) | 6h05 | 3:00 AM Milano, Autostazione Lampugnano | 1 transfer | |
Find all the dates and times for this journey
Compare prices and tickets Siena to Milan by train, bus, or flight
Nov 05
Nov 06
Nov 07
Nov 08
Nov 09
Nov 10
Nov 11
Nov 12
Nov 13
Nov 14
Nov 15
Nov 16
Nov 17
Nov 18
Nov 19
Nov 20
Nov 21
Nov 22
Nov 23
Nov 24
Nov 25
Journey information
Overview: Bus from Siena to Milan
Distance 293 km |
Average bus duration 5h 54m |
Cheapest ticket price €8 |
Buses per day 25 |
Direct buses 17 |
Fastest bus 4h 50m |
First bus 00:10 |
Last bus 23:55 |
Bus providers: FlixBus, Itabus, BlaBlaCar, Curcio Viaggi from Siena to MilanYou can travel by bus between Siena to Milan with FlixBus, Itabus, BlaBlaCar, Curcio Viaggi for as low as €8. When you search for schedules and tickets, Omio will show you the best journey
FlixBus
Itabus
BlaBlaCar
Curcio Viaggi
FAQs: Bus from Siena to Milan

When departing from Siena, you have various coach station options to start your journey from including Siena, Stazione FS (Piazzale Carlo Rosselli), Siena, Siena/Viale Pietro Toselli and Siena, Via Fiorentina 135/Stellino. When arriving in Milan, you can end your trip in coach stations like Orio al Serio, Milan Bergamo Airport (Bus station), Milano, Milan Linate Airport and Milano, Autostazione Lampugnano.
Passengers board the coach most frequently from Siena, Stazione FS (Piazzale Carlo Rosselli), which is located around 1.5 miles (2.4 km) away from the city centre, and they get off the coach at Orio al Serio, Milan Bergamo Airport (Bus station), located 28.2 miles (45.5 km) away from the city centre.
To find the cheapest bus tickets for your trip from Siena to Milan, follow these tips:
Start your search now and compare ticket prices to find the best deal!
popular bus stations
Popular bus stations from Siena to Milan
- 06:00-23:00
- Free Wi-Fi
- Cafeteria Milano (in the station)
- Trattoria San Donato (0.5 km)
- Burger House (0.7 km).
- Available outside the station.
- Elevators, ramps
- Available in the station.
- Metro: M3 Bus: 121, 132, 133
- 06:00-23:00
- Free Wi-Fi
- Cafeteria Lampugnano (in the station)
- Trattoria Milano (0.5 km)
- Pizza Express (0.7 km).
- Available outside the station.
- Elevators, ramps
- Available in the station.
- Metro: M1 Bus: 68, 78, 80
- 06:00-22:00
- Free Wi-Fi
- Cafeteria Italiana (in the station)
- Fast Food Express (in the station)
- Trattoria Milano (0.5 km).
- Available outside the station.
- Elevators, ramps
- Available in the station.
- Bus: 121, 132 Metro: M3
Most popular bus connections from Siena
More options for your journey from Siena to Milan
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