The cheapest and fastest trains from Pisa to Milan Centrale
Cheapest price
€27
Average price
€59
Fastest journey
3 h 18 m
Average duration
3 h 20 m
Trains per day
39
Distance
218 km
The best way to find a cheap train ticket from Pisa to Milan Centrale is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Pisa to Milan Centrale will cost around €59 if you buy it on the day, but the cheapest tickets can be found for only €27.
Of the 39 trains that leave Pisa for Milan Centrale on Sat, Mar 07, 8 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Sat, Mar 07 the direct trains cover the 218 km distance in an average of 3 h 20 m but if you time it right, some trains will get you there in just 3 h 18 m .
On Sat, Mar 07 the slowest trains will take 3 h 23 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
Regionale TRENORD 10502 · Treno 2296 effettuato con bus FI998
Regionale 2296 · Treno 2296 effettuato con bus FI998
Regionale TRENORD 10502 · Regionale TRENORD 2186
Regionale 2294 · Regionale TTPER 11018 · Regionale TRENORD 2166
Regionale 19360 · Regionale Veloce 3278 · Regionale Veloce 3044
TUSCANY LINE 4020+
FRECCIAROSSA 9520
TUSCANY LINE 18300+
FRECCIAROSSA 9584
ETRUSCHI LINE 4014+
FRECCIAROSSA 9512
Tuscany Line 4052+
FRECCIAROSSA 1000 9556
Tuscany Line 4038+
FRECCIAROSSA 9540Travel Information
Compare train and bus for Pisa to Milan Centrale
Omio recommends booking the train as it is the most popular option from Pisa to Milan Centrale among Omio's users. If you are prioritising price take the bus with prices starting from €11. For those with little time consider booking a train which can get you there in 3h 49m. The ticket price range depends on the travel mode: a bus costs an average of €11, and a train costs an average of €16.
Distance: 218 km
Compare train with
Most popular Train | Bus |
|---|---|
€24 Average price | €23 Average price Cheapest |
4h 19m Average total duration Fastest 3h 49m Onboard + 30m Additional time* | 4h 26m Average total duration 3h 56m Onboard + 30m Additional time* |
![]() Most popular train company | ![]() Most popular bus company |
Direct Options | Direct Options |
Live departures
Pisa to Milan Centrale train times
The table below shows live departures for Pisa to Milan Centrale trains for today, Friday, March 6. You can also manually refresh the results below to see updated train journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
ETRUSCHI LINE 4048+ FRECCIAROSSA 9552 | 4:25 PM Pisa Centrale | 3h25 | 7:50 PM Milan Centrale | 1 transfer | |
Intercity 684 | 4:31 PM Pisa Centrale | 4h28 | 8:59 PM Milan Centrale | 0 transfersDirect | |
Tuscany Line 4052+ FRECCIAROSSA 1000 9556 | 5:29 PM Pisa Centrale | 3h21 | 8:50 PM Milan Centrale | 1 transfer | |
Regionale 2296 · Treno 2296 effettuato con bus FI998 | 5:45 PM Pisa Centrale | 5h30 | 11:15 PM Milan Centrale | 1 transfer | |
Intercity 518+ Regionale Veloce 3047 | 5:55 PM Pisa Centrale | 4h44 | 10:39 PM Milan Centrale | 1 transfer | |
TUSCANY LINE 4058+ FRECCIAROSSA 1000 9560 | 6:25 PM Pisa Centrale | 3h25 | 9:50 PM Milan Centrale | 1 transfer | |
Regionale 18320+ FRECCIAROSSA 9592 | 6:58 PM Pisa Centrale | 3h52 | 10:50 PM Milan Centrale | 1 transfer | |
| Saturday, March 7 | |||||
Regionale 18250+ FRECCIAROSSA 1000 9504 | 3:15 AM Pisa Centrale | 4h35 | 7:50 AM Milan Centrale | 1 transfer | |
Intercity 658 | 4:31 AM Pisa Centrale | 4h33 | 9:04 AM Milan Centrale | 0 transfersDirect | |
Regionale 2294 · Regionale TTPER 11018 · Regionale TRENORD 2166 | 4:48 AM Pisa Centrale | 6h52 | 11:40 AM Milan Centrale | 2 transfers | |
Tuscany Line 18260+ FRECCIAROSSA 1000 9508 | 5:24 AM Pisa Centrale | 3h26 | 8:50 AM Milan Centrale | 1 transfer | |
Intercity 662 | 5:33 AM Pisa Centrale | 4h26 | 9:59 AM Milan Centrale | 0 transfersDirect | |
ETRUSCHI LINE 4014+ FRECCIAROSSA 9512 | 6:30 AM Pisa Centrale | 3h20 | 9:50 AM Milan Centrale | 1 transfer | |
ETRUSCHI LINE 18268+ FRECCIAROSSA 1000 9406 · FRECCIAROSSA 1000 9616 | 6:47 AM Pisa Centrale | 3h48 | 10:35 AM Milan Centrale | 2 transfers | |
Regionale 18272+ FRECCIAROSSA 9516 | 7:06 AM Pisa Centrale | 3h44 | 10:50 AM Milan Centrale | 1 transfer | |
ETRUSCHI LINE 4016+ FRECCIAROSSA 9490 · FRECCIAROSSA 8810 | 7:32 AM Pisa Centrale | 3h58 | 11:30 AM Milan Centrale | 2 transfers | |
Intercity 666 | 7:37 AM Pisa Centrale | 5h22 | 12:59 PM Milan Centrale | 0 transfersDirect | |
TUSCANY LINE 4020+ FRECCIAROSSA 9520 | 8:32 AM Pisa Centrale | 3h18 | 11:50 AM Milan Centrale | 1 transfer | |
TUSCANY LINE 4026+ FRECCIAROSSA 9524 | 9:24 AM Pisa Centrale | 3h26 | 12:50 PM Milan Centrale | 1 transfer | |
TUSCANY LINE 4028+ FRECCIAROSSA 1000 9416 · FRECCIAROSSA 8814 | 10:02 AM Pisa Centrale | 3h23 | 1:25 PM Milan Centrale | 2 transfers | |
Regionale 19342 · Regionale 19248+ BUS LP606 | 10:20 AM Pisa Centrale | 7h19 | 5:39 PM Milan Centrale | 2 transfers | |
TUSCANY LINE 4030+ FRECCIAROSSA 1000 9514 | 10:25 AM Pisa Centrale | 3h25 | 1:50 PM Milan Centrale | 1 transfer | |
Intercity 670 | 10:33 AM Pisa Centrale | 4h26 | 2:59 PM Milan Centrale | 0 transfersDirect | |
TUSCANY LINE 4032+ FRECCIAROSSA 9532 | 11:25 AM Pisa Centrale | 3h25 | 2:50 PM Milan Centrale | 1 transfer | |
Intercity 510+ Regionale Veloce 3075 | 12:01 PM Pisa Centrale | 4h38 | 4:39 PM Milan Centrale | 1 transfer | |
Intercity 674 | 12:18 PM Pisa Centrale | 4h41 | 4:59 PM Milan Centrale | 0 transfersDirect | |
TUSCANY LINE 18300+ FRECCIAROSSA 9584 | 12:30 PM Pisa Centrale | 3h20 | 3:50 PM Milan Centrale | 1 transfer | |
Tuscany Line 4038+ FRECCIAROSSA 9540 | 1:27 PM Pisa Centrale | 3h23 | 4:50 PM Milan Centrale | 1 transfer | |
Regionale 19354+ Intercity 680 | 1:33 PM Pisa Centrale | 5h31 | 7:04 PM Milan Centrale | 1 transfer | |
Regionale Veloce 4042+ FRECCIAROSSA 9544 | 2:25 PM Pisa Centrale | 3h25 | 5:50 PM Milan Centrale | 1 transfer | |
Regionale 19360 · Regionale Veloce 3278 · Regionale Veloce 3044 | 2:50 PM Pisa Centrale | 5h49 | 8:39 PM Milan Centrale | 2 transfers | |
Intercity 590+ Regionale Veloce 3278 · Regionale Veloce 3044 | 3:11 PM Pisa Centrale | 5h28 | 8:39 PM Milan Centrale | 2 transfers | |
Intercity 590 | 3:11 PM Pisa Centrale | 5h49 | 9:00 PM Milan Centrale | 0 transfersDirect | |
Tuscany Line 4044+ FRECCIAROSSA 9588 | 3:25 PM Pisa Centrale | 3h25 | 6:50 PM Milan Centrale | 1 transfer | |
FRECCIABIANCA 8620 | 3:46 PM Pisa Centrale | 3h58 | 7:44 PM Milan Centrale | 0 transfersDirect | |
Find all the dates and times for this journey
Compare prices and tickets Pisa to Milan Centrale by train or bus
Compare train and bus prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Mar 07
Mar 08
Mar 09
Mar 10
Mar 11
Mar 12
Mar 13
Mar 14
Mar 15
Mar 16
Mar 17
Mar 18
Mar 19
Mar 20
Mar 21
Mar 22
Mar 23
Mar 24
Mar 25
Mar 26
Mar 27
Why should you book Pisa to Milan Centrale trains with Omio?
Why book with Omio vs Italo?
- Compare with other providers: On Omio, you can not only buy tickets for Italo, but also compare tickets for the likes of Intercity, Regionale, Frecciarossa or Frecciabianca to find the best option for your trip from Pisa to Milan Centrale.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Italo with all available travel options, which are train and bus to ensure you get the best deal for traveling from Pisa to Milan Centrale.
Journey information
Overview: Train from Pisa to Milan Centrale
Trains from Pisa to Milan Centrale run on average 39 times per day, taking around 3h 49m. Cheap train tickets for this journey start at €16 but you can travel from only €11 by bus.
There are 7 trains per day. The earliest train runs at 04:42, the last at 21:53. The fastest train covers the 218 km distance in 3h 18m.
Distance 218 km |
Average train duration 3h 49m |
Cheapest ticket price €16 |
Trains per day 39 |
Direct trains 7 |
Fastest train 3h 18m |
First train 04:42 |
Last train 21:53 |
Train companies: Italo, Intercity, Regionale, Frecciarossa, Frecciabianca, Intercity Notte, Frecciargento from Pisa to Milan Centrale trainsItalo, Intercity, Regionale, Frecciarossa, Frecciabianca, Intercity Notte, Frecciargento trains will get you between Pisa and Milan Centrale from €11. With over 1000 travel companies on Omio, you can find the best train times and tickets for your trip.
Italo
Intercity
Regionale
Frecciarossa
Frecciabianca
Intercity Notte
Frecciargento
FAQs: Trains from Pisa to Milan Centrale
Find answers to the most common questions about traveling from Pisa to Milan Centrale by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Milan Centrale, this guide helps you travel smarter and with confidence.

popular train stations
Popular train stations from Pisa to Milan Centrale
- Mon - Sun: 06:00 - 20:30
- There is free Wi-Fi available at the McDonald's.
- There is a luggage storage office near the end of Platform 1.
- McDonald's
- Panetteria Binario 1
- Accessible facilities including barrier-free restrooms, elevators, ramps, and disabled parking. Sala Blu mobility assistance available from 07:45 to 22:30 with advanced one-hour notice.
- Hotel NH Pisa
- Hotel La Pace
- Hotel Maria
- Mon - Sun: 06:00 - 20:30
- Located just outside the station on Piazza Vittorio Emanuele II.
- Bus lines: 1
- Train lines: Pisamover (S2), FA, FB, IC, ICN, RV, R, EN
- 24/7
- Ristorante pizzeria
- SushiKing
- Ristorante Cinese Oriente
- Elevators on every platform. Sala Blu services can be reached at +39 0647308579.
- Rosso di Sera Relais Tuscany
- Le Cascine
- Camping Village Torre Pendente
- 24/7
- Train lines: REG, RV
- Mon - Sun: 05:50 - 22:20
- Free WiFi in the station.
- Provided by KiPoint and located on the ground floor, on the side of Piazza Luigi di Savoia. It is open every day from 06:00 to 23:00.
- Venchi
- Panzera Coffee
- Burger King
- Bar Motta
- Caffè Napoli
- VyTA Boulangerie
- Spontini
- Starbucks
- Dispensa Emilia
- McDonald's
- & many more
- Station is wheelchair accessible, has elevators and the Sala Blu, Trenitalia's office of assistance for disabled travelers, is next to Platform 4.
- Glam Hotel Milano
- NYX MIlan
- iQ Hotel Milano
- Mon - Sun: 05:50 - 22:20
- Located next to the ticket office on the ground floor in the shopping gallery.
- Metro lines: M2 (green), M3 (yellow)
- Tram lines: 1
- Bus lines: 5, 9, 10, 42, 81, 87, 152, 728, N26, NM2, NM3, Air Bus, Orio Shuttle
- Train lines: FR, FB, EC, Thello, XP2, R28, IC, ICN, RV, R, Regio, Italo
Most popular train connections from Pisa
More options for your journey from Pisa to Milan Centrale
Here are some other resources that might have the information you need





