The cheapest and fastest trains from Pisa to Milan Centrale
Cheapest price
€16
Average price
€21
Fastest journey
4 h 13 m
Average duration
4 h 56 m
Trains per day
4
Distance
218 km
The best way to find a cheap train ticket from Pisa to Milan Centrale is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Pisa to Milan Centrale will cost around €21 if you buy it on the day, but the cheapest tickets can be found for only €16.
Of the 4 trains that leave Pisa for Milan Centrale on Wed, Apr 22, 4 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Wed, Apr 22 the direct trains cover the 218 km distance in an average of 4 h 56 m but if you time it right, some trains will get you there in just 4 h 13 m .
On Wed, Apr 22 the slowest trains will take 6 h 43 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
4:42 PM4h13Pisa8:55 PMMilan Centrale€161One-way0 transfers
4:42 AM4h21Pisa9:03 AMMilan Centrale€221One-way0 transfers
5:00 AM6h43Pisa11:43 AMMilan Centrale€241One-way0 transfers
5:57 PM4h28Pisa10:25 PMMilan Centrale€241One-way0 transfers
4:42 PM4h13Pisa8:55 PMMilan Centrale€161One-way0 transfers
4:42 AM4h21Pisa9:03 AMMilan Centrale€221One-way0 transfers
5:57 PM4h28Pisa10:25 PMMilan Centrale€241One-way0 transfers
5:00 AM6h43Pisa11:43 AMMilan Centrale€241One-way0 transfers
Travel Information
Compare bus and train for Pisa to Milan Centrale
Omio recommends booking the train as it is the most popular option from Pisa to Milan Centrale among Omio's users. If you are prioritising price take the bus with prices starting from €11. For those with little time consider booking a train which can get you there in 3h 49m. The ticket price range depends on the travel mode: a bus costs an average of €11, and a train costs an average of €16.
Distance: 218 km
Compare train with
Most popular Train | Bus |
|---|---|
€24 Average price | €23 Average price Cheapest |
4h 19m Average total duration Fastest 3h 49m Onboard + 30m Additional time* | 4h 26m Average total duration 3h 56m Onboard + 30m Additional time* |
![]() Most popular train company | ![]() Most popular bus company |
Direct Options | Direct Options |
Live departures
Pisa to Milan Centrale train times
The table below shows live departures for Pisa to Milan Centrale trains for today, Tuesday, April 21. You can also manually refresh the results below to see updated train journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
Intercity 684 | 5:31 PM Pisa Centrale | 4h24 | 9:55 PM Milan Centrale | 0 transfersDirect | |
Regionale Veloce 4052+ Intercity 596 | 6:29 PM Pisa Centrale | 4h48 | 11:17 PM Milan Centrale | 1 transfer | |
Regionale Veloce 4052+ FRECCIAROSSA 1000 9556 | 6:29 PM Pisa Centrale | 3h21 | 9:50 PM Milan Centrale | 1 transfer | |
Intercity 518+ Regionale Veloce 3047 | 6:55 PM Pisa Centrale | 4h40 | 11:35 PM Milan Centrale | 1 transfer | |
Regionale Veloce 4058+ FRECCIAROSSA 1000 9560 | 7:25 PM Pisa Centrale | 3h25 | 10:50 PM Milan Centrale | 1 transfer | |
Regionale 18320+ FRECCIAROSSA 9592 | 7:58 PM Pisa Centrale | 3h52 | 11:50 PM Milan Centrale | 1 transfer | |
Regionale 19382 · treno 12210 effettuato con bus GE032 · Regionale Veloce 3016 | 9:40 PM Pisa Centrale | 9h55 | 7:35 AM Milan Centrale | 2 transfers | |
Intercity 822+ treno 12210 effettuato con bus GE032 · Regionale Veloce 3016 | 10:11 PM Pisa Centrale | 9h24 | 7:35 AM Milan Centrale | 2 transfers | |
FRECCIARGENTO 8598+ treno 12210 effettuato con bus GE032 · Regionale Veloce 3016 | 10:50 PM Pisa Centrale | 8h45 | 7:35 AM Milan Centrale | 2 transfers | |
| Wednesday, April 22 | |||||
![]() | 4:42 AM Pisa | 4h21 | 9:03 AM Milan Centrale | 0 transfersDirect | |
![]() | 5:00 AM Pisa | 6h43 | 11:43 AM Milan Centrale | 0 transfersDirect | |
This is the last train of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Pisa to Milan Centrale by bus or train
Compare bus and train prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Apr 22
Apr 23
Apr 24
Apr 25
Apr 26
Apr 27
Apr 28
Apr 29
Apr 30
May 01
May 02
May 03
May 04
May 05
May 06
May 07
May 08
May 09
May 10
May 11
May 12
Why should you book Pisa to Milan Centrale trains with Omio?
Why book with Omio vs Italo?
- Compare with other providers: On Omio, you can not only buy tickets for Italo, but also compare tickets for the likes of Intercity, Regionale, Frecciarossa or Frecciabianca to find the best option for your trip from Pisa to Milan Centrale.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Italo with all available travel options, which are bus and train to ensure you get the best deal for traveling from Pisa to Milan Centrale.
Journey information
Overview: Train from Pisa to Milan Centrale
Trains from Pisa to Milan Centrale run on average 39 times per day, taking around 3h 49m. Cheap train tickets for this journey start at €16 but you can travel from only €11 by bus.
There are 7 trains per day. The earliest train runs at 04:42, the last at 21:53. The fastest train covers the 218 km distance in 3h 18m.
Distance 218 km |
Average train duration 3h 49m |
Cheapest ticket price €16 |
Trains per day 39 |
Direct trains 7 |
Fastest train 3h 18m |
First train 4:42 AM |
Last train 9:53 PM |
Cheapest Month Dec |
Cheapest Day Sat |
High Season Apr - Jun |
Low Season Jan - Mar |
Busiest Day Fri |
Least Busy Day Mon |
Train companies: Italo, Intercity, Regionale, Frecciarossa, Frecciabianca, Intercity Notte, Frecciargento from Pisa to Milan Centrale trainsItalo, Intercity, Regionale, Frecciarossa, Frecciabianca, Intercity Notte, Frecciargento trains will get you between Pisa and Milan Centrale from €11. With over 1000 travel companies on Omio, you can find the best train times and tickets for your trip.
Italo
Intercity
Regionale
Frecciarossa
Frecciabianca
Intercity Notte
Frecciargento
FAQs: Trains from Pisa to Milan Centrale
Find answers to the most common questions about traveling from Pisa to Milan Centrale by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Milan Centrale, this guide helps you travel smarter and with confidence.

popular train stations
Popular train stations from Pisa to Milan Centrale
- Mon - Sun: 06:00 - 20:30
- There is free Wi-Fi available at the McDonald's.
- There is a luggage storage office near the end of Platform 1.
- McDonald's
- Panetteria Binario 1
- Accessible facilities including barrier-free restrooms, elevators, ramps, and disabled parking. Sala Blu mobility assistance available from 07:45 to 22:30 with advanced one-hour notice.
- Hotel NH Pisa
- Hotel La Pace
- Hotel Maria
- Mon - Sun: 06:00 - 20:30
- Located just outside the station on Piazza Vittorio Emanuele II.
- Bus lines: 1
- Train lines: Pisamover (S2), FA, FB, IC, ICN, RV, R, EN
- 24/7
- Ristorante pizzeria
- SushiKing
- Ristorante Cinese Oriente
- Elevators on every platform. Sala Blu services can be reached at +39 0647308579.
- Rosso di Sera Relais Tuscany
- Le Cascine
- Camping Village Torre Pendente
- 24/7
- Train lines: REG, RV
- Mon - Sun: 05:50 - 22:20
- Free WiFi in the station.
- Provided by KiPoint and located on the ground floor, on the side of Piazza Luigi di Savoia. It is open every day from 06:00 to 23:00.
- Venchi
- Panzera Coffee
- Burger King
- Bar Motta
- Caffè Napoli
- VyTA Boulangerie
- Spontini
- Starbucks
- Dispensa Emilia
- McDonald's
- & many more
- Station is wheelchair accessible, has elevators and the Sala Blu, Trenitalia's office of assistance for disabled travelers, is next to Platform 4.
- Glam Hotel Milano
- NYX MIlan
- iQ Hotel Milano
- Mon - Sun: 05:50 - 22:20
- Located next to the ticket office on the ground floor in the shopping gallery.
- Metro lines: M2 (green), M3 (yellow)
- Tram lines: 1
- Bus lines: 5, 9, 10, 42, 81, 87, 152, 728, N26, NM2, NM3, Air Bus, Orio Shuttle
- Train lines: FR, FB, EC, Thello, XP2, R28, IC, ICN, RV, R, Regio, Italo
Most popular train connections from Pisa
More options for your journey from Pisa to Milan Centrale
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