The cheapest and fastest trains from Pisa Centrale to Milan Centrale
Cheapest price
€28
Average price
€52
Fastest journey
3 h 12 m
Average duration
3 h 16 m
Trains per day
38
Distance
219 km
The best way to find a cheap train ticket from Pisa Centrale to Milan Centrale is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Pisa Centrale to Milan Centrale will cost around €52 if you buy it on the day, but the cheapest tickets can be found for only €28.
Of the 38 trains that leave Pisa Centrale for Milan Centrale on Tue, May 05, 6 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Tue, May 05 the direct trains cover the 219 km distance in an average of 3 h 16 m but if you time it right, some trains will get you there in just 3 h 12 m .
On Tue, May 05 the slowest trains will take 3 h 18 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
Regionale 19388 · Regionale Veloce 3261 · Regionale Veloce 30288:18 AM5h17Pisa Centrale1:35 PMMilan Centrale€281One-way2 transfers
Regionale 19382 · treno 12210 effettuato con bus GE032 · Regionale Veloce 30169:40 PM9h55Pisa Centrale7:35 AMMilan Centrale€281One-way2 transfers
Regionale 18371 · Regionale Veloce 3274 · Regionale Veloce 30402:06 PM5h29Pisa Centrale7:35 PMMilan Centrale€281One-way2 transfers
Regionale 18377 · Regionale Veloce 3278 · Regionale Veloce 30444:06 PM5h29Pisa Centrale9:35 PMMilan Centrale€281One-way2 transfers
Regionale 18489 · Autobus TTPER B0400 · Regionale Veloce TTPER 24748:50 AM7h55Pisa Centrale4:45 PMMilan Centrale€321One-way2 transfers
Regionale Veloce 4014+
FRECCIAROSSA 95127:38 AM3h12Pisa Centrale10:50 AMMilan Centrale€661One-way1 transfer
Regionale 4028+
FRECCIAROSSA 9416 · FRECCIAROSSA 881411:09 AM3h16Pisa Centrale2:25 PMMilan Centrale€881One-way2 transfers
Regionale Veloce 4060+
FRECCIAROSSA 95928:32 PM3h18Pisa Centrale11:50 PMMilan Centrale€661One-way1 transfer
Regionale Veloce 4026+
FRECCIAROSSA 952410:32 AM3h18Pisa Centrale1:50 PMMilan Centrale€661One-way1 transfer
Regionale Veloce 4052+
FRECCIAROSSA 95566:32 PM3h18Pisa Centrale9:50 PMMilan Centrale€661One-way1 transfer
Travel Information
Compare train and bus for Pisa Centrale to Milan Centrale
Omio recommends booking the train as it is the most popular option from Pisa Centrale to Milan Centrale among Omio's users. If you are prioritising price take the bus with prices starting from €12. For those with little time consider booking a train which can get you there in 3h 49m. The ticket price range depends on the travel mode: a bus costs an average of €12, and a train costs an average of €16.
Distance: 219 km
Compare train with
Most popular Train | Bus |
|---|---|
€25 Average price | €24 Average price Cheapest |
4h 19m Average total duration Fastest 3h 49m Onboard + 30m Additional time* | 4h 41m Average total duration 4h 11m Onboard + 30m Additional time* |
![]() Most popular train company | ![]() Most popular bus company |
Direct Options | Direct Options |
Live departures
Pisa Centrale to Milan Centrale train times
The table below shows live departures for Pisa Centrale to Milan Centrale trains for today, Monday, May 4. You can also manually refresh the results below to see updated train journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
Regionale Veloce 4042+ FRECCIAROSSA 9544 | 3:32 PM Pisa Centrale | 3h18 | 6:50 PM Milan Centrale | 1 transfer | |
Regionale 18377 · Regionale Veloce 3278 · Regionale Veloce 3044 | 4:06 PM Pisa Centrale | 5h29 | 9:35 PM Milan Centrale | 2 transfers | |
Regionale Veloce 4044+ FRECCIAROSSA 9588 | 4:32 PM Pisa Centrale | 3h18 | 7:50 PM Milan Centrale | 1 transfer | |
FRECCIABIANCA 8620 | 4:56 PM Pisa Centrale | 3h44 | 8:40 PM Milan Centrale | 0 transfersDirect | |
Regionale Veloce 4046+ FRECCIAROSSA 9428 · FRECCIAROSSA 9652 | 5:09 PM Pisa Centrale | 3h21 | 8:30 PM Milan Centrale | 2 transfers | |
Regionale Veloce 4048+ FRECCIAROSSA 9552 | 5:32 PM Pisa Centrale | 3h18 | 8:50 PM Milan Centrale | 1 transfer | |
Intercity 684 | 5:42 PM Pisa Centrale | 4h13 | 9:55 PM Milan Centrale | 0 transfersDirect | |
Regionale Veloce 4052+ FRECCIAROSSA 9556 | 6:32 PM Pisa Centrale | 3h18 | 9:50 PM Milan Centrale | 1 transfer | |
Regionale Veloce 4052+ Intercity 596 | 6:32 PM Pisa Centrale | 4h45 | 11:17 PM Milan Centrale | 1 transfer | |
Intercity 518+ Regionale Veloce 3047 | 7:03 PM Pisa Centrale | 4h32 | 11:35 PM Milan Centrale | 1 transfer | |
Regionale Veloce 4058+ FRECCIAROSSA 9560 | 7:32 PM Pisa Centrale | 3h18 | 10:50 PM Milan Centrale | 1 transfer | |
Regionale Veloce 4060+ FRECCIAROSSA 9592 | 8:32 PM Pisa Centrale | 3h18 | 11:50 PM Milan Centrale | 1 transfer | |
Regionale 19382 · Regionale 12210 · Regionale Veloce 3016 | 9:40 PM Pisa Centrale | 9h55 | 7:35 AM Milan Centrale | 2 transfers | |
Intercity 522+ Regionale 12210 · Regionale Veloce 3016 | 10:53 PM Pisa Centrale | 8h42 | 7:35 AM Milan Centrale | 2 transfers | |
| Tuesday, May 5 | |||||
InterCityNotte 37278+ Regionale Veloce 3019 | 4:37 AM Pisa Centrale | 4h58 | 9:35 AM Milan Centrale | 1 transfer | |
Intercity 658 | 5:42 AM Pisa Centrale | 4h18 | 10:00 AM Milan Centrale | 0 transfersDirect | |
Intercity 662 | 6:42 AM Pisa Centrale | 4h13 | 10:55 AM Milan Centrale | 0 transfersDirect | |
Regionale Veloce 4014+ FRECCIAROSSA 9512 | 7:38 AM Pisa Centrale | 3h12 | 10:50 AM Milan Centrale | 1 transfer | |
Regionale 19388 · Regionale Veloce 3261 · Regionale Veloce 3028 | 8:18 AM Pisa Centrale | 5h17 | 1:35 PM Milan Centrale | 2 transfers | |
Regionale Veloce 4016+ FRECCIAROSSA 9516 | 8:32 AM Pisa Centrale | 3h18 | 11:50 AM Milan Centrale | 1 transfer | |
Regionale 18489 · Autobus TTPER B0400 · Regionale Veloce TTPER 2474 | 8:50 AM Pisa Centrale | 7h55 | 4:45 PM Milan Centrale | 2 transfers | |
Intercity 666 | 8:55 AM Pisa Centrale | 5h00 | 1:55 PM Milan Centrale | 0 transfersDirect | |
Regionale Veloce 4018+ FRECCIAROSSA 9490 · FRECCIAROSSA 8810 | 9:09 AM Pisa Centrale | 3h21 | 12:30 PM Milan Centrale | 2 transfers | |
Regionale Veloce 4020+ FRECCIAROSSA 9520 | 9:32 AM Pisa Centrale | 3h18 | 12:50 PM Milan Centrale | 1 transfer | |
InterCityNotte 794+ Intercity 745 | 9:49 AM Pisa Centrale | 5h06 | 2:55 PM Milan Centrale | 1 transfer | |
Regionale Veloce 4026+ FRECCIAROSSA 9524 | 10:32 AM Pisa Centrale | 3h18 | 1:50 PM Milan Centrale | 1 transfer | |
Regionale 18361+ Intercity 670 | 11:06 AM Pisa Centrale | 4h49 | 3:55 PM Milan Centrale | 1 transfer | |
Regionale 4028+ FRECCIAROSSA 9416 · FRECCIAROSSA 8814 | 11:09 AM Pisa Centrale | 3h16 | 2:25 PM Milan Centrale | 2 transfers | |
Regionale Veloce 4030+ FRECCIAROSSA 9514 | 11:30 AM Pisa Centrale | 3h20 | 2:50 PM Milan Centrale | 1 transfer | |
Regionale 18290+ Intercity 588 · Intercity 608 | 12:01 PM Pisa Centrale | 5h44 | 5:45 PM Milan Centrale | 2 transfers | |
Regionale Veloce 4032+ FRECCIAROSSA 9532 | 12:32 PM Pisa Centrale | 3h18 | 3:50 PM Milan Centrale | 1 transfer | |
Regionale Veloce 4036+ FRECCIAROSSA 9584 | 1:32 PM Pisa Centrale | 3h18 | 4:50 PM Milan Centrale | 1 transfer | |
Intercity 674 | 1:39 PM Pisa Centrale | 4h16 | 5:55 PM Milan Centrale | 0 transfersDirect | |
Intercity 510 · Intercity 635 | 1:47 PM Pisa Centrale | 5h08 | 6:55 PM Milan Centrale | 1 transfer | |
Regionale 18304+ Intercity 590 | 2:01 PM Pisa Centrale | 5h24 | 7:25 PM Milan Centrale | 1 transfer | |
Regionale 18371 · Regionale Veloce 3274 · Regionale Veloce 3040 | 2:06 PM Pisa Centrale | 5h29 | 7:35 PM Milan Centrale | 2 transfers | |
Regionale Veloce 4038+ FRECCIAROSSA 9540 | 2:32 PM Pisa Centrale | 3h18 | 5:50 PM Milan Centrale | 1 transfer | |
Regionale 18373+ Intercity 680 | 3:06 PM Pisa Centrale | 4h54 | 8:00 PM Milan Centrale | 1 transfer | |
This is the last train of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Pisa Centrale to Milan Centrale by train or bus
Compare train and bus prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Why should you book Pisa Centrale to Milan Centrale trains with Omio?
Why book with Omio vs Italo?
- Compare with other providers: On Omio, you can not only buy tickets for Italo, but also compare tickets for the likes of Intercity, Regionale, Frecciarossa or Frecciabianca to find the best option for your trip from Pisa Centrale to Milan Centrale.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Italo with all available travel options, which are train and bus to ensure you get the best deal for traveling from Pisa Centrale to Milan Centrale.
Journey information
Overview: Train from Pisa Centrale to Milan Centrale
Trains from Pisa Centrale to Milan Centrale run on average 40 times per day, taking around 3h 49m. Cheap train tickets for this journey start at €16 but you can travel from only €12 by bus.
There are 7 trains per day. The earliest train runs at 04:42, the last at 19:32. The fastest train covers the 219 km distance in 3h 18m.
Distance 219 km |
Average train duration 3h 49m |
Cheapest ticket price €16 |
Trains per day 40 |
Direct trains 7 |
Fastest train 3h 18m |
First train 4:42 AM |
Last train 7:32 PM |
Cheapest Month Oct |
Cheapest Day Fri |
High Season Jul - Sep |
Low Season Jan - Mar |
Busiest Day Mon |
Least Busy Day Fri |
Train companies: Italo, Intercity, Regionale, Frecciarossa, Frecciabianca, Intercity Notte, Frecciargento from Pisa Centrale to Milan Centrale trainsItalo, Intercity, Regionale, Frecciarossa, Frecciabianca, Intercity Notte, Frecciargento trains will get you between Pisa Centrale and Milan Centrale from €12. With over 1000 travel companies on Omio, you can find the best train times and tickets for your trip.
Italo
Intercity
Regionale
Frecciarossa
Frecciabianca
Intercity Notte
Frecciargento
FAQs: Trains from Pisa Centrale to Milan Centrale
Find answers to the most common questions about traveling from Pisa Centrale to Milan Centrale by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Milan Centrale, this guide helps you travel smarter and with confidence.

popular train stations
Popular train stations from Pisa Centrale to Milan Centrale
- Mon - Sun: 06:00 - 20:30
- There is free Wi-Fi available at the McDonald's.
- There is a luggage storage office near the end of Platform 1.
- McDonald's
- Panetteria Binario 1
- Accessible facilities including barrier-free restrooms, elevators, ramps, and disabled parking. Sala Blu mobility assistance available from 07:45 to 22:30 with advanced one-hour notice.
- Hotel NH Pisa
- Hotel La Pace
- Hotel Maria
- Mon - Sun: 06:00 - 20:30
- Located just outside the station on Piazza Vittorio Emanuele II.
- Bus lines: 1
- Train lines: Pisamover (S2), FA, FB, IC, ICN, RV, R, EN
- Mon - Sun: 05:50 - 22:20
- Free WiFi in the station.
- Provided by KiPoint and located on the ground floor, on the side of Piazza Luigi di Savoia. It is open every day from 06:00 to 23:00.
- Venchi
- Panzera Coffee
- Burger King
- Bar Motta
- Caffè Napoli
- VyTA Boulangerie
- Spontini
- Starbucks
- Dispensa Emilia
- McDonald's
- & many more
- Station is wheelchair accessible, has elevators and the Sala Blu, Trenitalia's office of assistance for disabled travelers, is next to Platform 4.
- Glam Hotel Milano
- NYX MIlan
- iQ Hotel Milano
- Mon - Sun: 05:50 - 22:20
- Located next to the ticket office on the ground floor in the shopping gallery.
- Metro lines: M2 (green), M3 (yellow)
- Tram lines: 1
- Bus lines: 5, 9, 10, 42, 81, 87, 152, 728, N26, NM2, NM3, Air Bus, Orio Shuttle
- Train lines: FR, FB, EC, Thello, XP2, R28, IC, ICN, RV, R, Regio, Italo
Most popular train connections from Pisa Centrale
More options for your journey from Pisa Centrale to Milan Centrale
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