The cheapest and fastest trains from Florence Santa Maria Novella to Milan Centrale
Cheapest price
€26
Average price
€51
Fastest journey
1 h 55 m
Average duration
1 h 55 m
Trains per day
63
Distance
250 km
The best way to find a cheap train ticket from Florence Santa Maria Novella to Milan Centrale is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Florence Santa Maria Novella to Milan Centrale will cost around €51 if you buy it on the day, but the cheapest tickets can be found for only €26.
Of the 63 trains that leave Florence Santa Maria Novella for Milan Centrale on Wed, Nov 12, 29 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Wed, Nov 12 the direct trains cover the 250 km distance in an average of 1 h 55 m but if you time it right, some trains will get you there in just 1 h 55 m .
On Wed, Nov 12 the slowest trains will take 1 h 55 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
Tuscany Line 18478 · Autobus TTPER B0444 · Regionale Veloce TTPER 2486
TUSCANY LINE 18492 · Autobus TTPER B0440 · Regionale Veloce TTPER 2478
Regionale 18466 · Autobus TTPER B0434 · Regionale Veloce TTPER 2470
Tuscany Line 18472 · Autobus TTPER B0442 · Regionale Veloce TTPER 2482
Regionale 18460 · Autobus TTPER B0430 · Regionale Veloce TTPER 2466
9912
9924
9962
9916
9940Travel Information
Compare bus, train, and flight for Florence Santa Maria Novella to Milan Centrale
Omio recommends booking the train as it is the most popular option from Florence Santa Maria Novella to Milan Centrale among Omio's users. If you are prioritising price take the bus with prices starting from €9. For those with little time consider booking a train which can get you there in 3h 40m. The ticket price range depends on the travel mode: a bus costs an average of €9, and a flight costs an average of €103.
Distance: 250 km
Compare train with
Most popular Train | Bus | Flight |
|---|---|---|
€43 Average price | €20 Average price Cheapest | €185 Average price |
4h 10m Average total duration Fastest 3h 40m Onboard + 30m Additional time* | 5h 3m Average total duration 4h 33m Onboard + 30m Additional time* | 12h 32m Average total duration 9h 32m Onboard + 3h 0m Additional time* |
Direct Options | Direct Options | Direct Options |
Live departures
Florence Santa Maria Novella to Milan Centrale train times
The table below shows live departures for Florence Santa Maria Novella to Milan Centrale trains for today, Tuesday, November 11. You can also manually refresh the results below to see updated train journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
Regionale 18500 · Autobus FI668 · Regionale Veloce TTPER 2462 | 4:04 AM Florence Santa Maria Novella | 5h41 | 9:45 AM Milan Centrale | 2 transfers | |
Regionale 18460 · Autobus TTPER B0430 · Regionale Veloce TTPER 2466 | 5:38 AM Florence Santa Maria Novella | 6h07 | 11:45 AM Milan Centrale | 2 transfers | |
Tuscany Line 4013+ Intercity 666 | On time 6:28 AM Florence Santa Maria Novella | 6h27 | 12:55 PM Milan Centrale | 1 transfer | |
FRECCIAROSSA 1000 9404 · FRECCIAROSSA 1000 9610 | 7:20 AM Florence Santa Maria Novella | 2h15 | 9:35 AM Milan Centrale | 1 transfer | |
Intercity 580+ BUS L580A+ Intercity 1528 | 7:21 AM Florence Santa Maria Novella | 4h49 | 12:10 PM Milan Centrale | 2 transfers | |
Regionale 18466 · Autobus TTPER B0434 · Regionale Veloce TTPER 2470 | 7:37 AM Florence Santa Maria Novella | 6h08 | 1:45 PM Milan Centrale | 2 transfers | |
Regionale 18466 · Autobus TTPER B0434+ Intercity 604 | 7:37 AM Florence Santa Maria Novella | 5h03 | 12:40 PM Milan Centrale | 2 transfers | |
FRECCIAROSSA 9512 | 7:55 AM Florence Santa Maria Novella | 1h55 | 9:50 AM Milan Centrale | 0 transfersDirect | |
TUSCANY LINE 18508 · Autobus FI680+ Intercity 606 | 8:09 AM Florence Santa Maria Novella | 6h21 | 2:30 PM Milan Centrale | 2 transfers | |
FRECCIAROSSA 1000 9406 · FRECCIAROSSA 1000 9616 | 8:20 AM Florence Santa Maria Novella | 2h15 | 10:35 AM Milan Centrale | 1 transfer | |
9912 | 8:25 AM Florence Santa Maria Novella | 1h55 | 10:20 AM Milan Centrale | 0 transfersDirect | |
FRECCIAROSSA 9516 | 8:55 AM Florence Santa Maria Novella | 1h55 | 10:50 AM Milan Centrale | 0 transfersDirect | |
FRECCIAROSSA 9490 · FRECCIAROSSA 8810 | On time 9:20 AM Florence Santa Maria Novella | 2h10 | 11:30 AM Milan Centrale | 1 transfer | |
Regionale 18664 · Autobus TTPER B0436 · Regionale Veloce TTPER 2474 | 9:20 AM Florence Santa Maria Novella | 6h25 | 3:45 PM Milan Centrale | 2 transfers | |
9916 | 9:25 AM Florence Santa Maria Novella | 1h55 | 11:20 AM Milan Centrale | 0 transfersDirect | |
TUSCANY LINE 4021+ Intercity 670 | 9:28 AM Florence Santa Maria Novella | 5h27 | 2:55 PM Milan Centrale | 1 transfer | |
FRECCIAROSSA 9520 | 9:55 AM Florence Santa Maria Novella | 1h55 | 11:50 AM Milan Centrale | 0 transfersDirect | |
FRECCIAROSSA 9414 · FRECCIAROSSA 9806 | 10:20 AM Florence Santa Maria Novella | 2h05 | 12:25 PM Milan Centrale | 1 transfer | |
9920 | 10:25 AM Florence Santa Maria Novella | 1h55 | 12:20 PM Milan Centrale | 0 transfersDirect | |
Tuscany Line 18289+ Intercity 510+ Regionale Veloce 3035 | 10:38 AM Florence Santa Maria Novella | 5h57 | 4:35 PM Milan Centrale | 2 transfers | |
FRECCIAROSSA 9524 | 10:55 AM Florence Santa Maria Novella | 1h55 | 12:50 PM Milan Centrale | 0 transfersDirect | |
FRECCIAROSSA 1000 9416 · FRECCIAROSSA 8814 | 11:20 AM Florence Santa Maria Novella | 2h05 | 1:25 PM Milan Centrale | 1 transfer | |
9924 | 11:25 AM Florence Santa Maria Novella | 1h55 | 1:20 PM Milan Centrale | 0 transfersDirect | |
TUSCANY LINE 4029+ Intercity 674 | 11:28 AM Florence Santa Maria Novella | 5h27 | 4:55 PM Milan Centrale | 1 transfer | |
TUSCANY LINE 18492 · Autobus TTPER B0440 · Regionale Veloce TTPER 2478 | 11:37 AM Florence Santa Maria Novella | 6h08 | 5:45 PM Milan Centrale | 2 transfers | |
Regionale 18371 · Regionale Veloce 3274 · Regionale Veloce 3040 | 11:53 AM Florence Santa Maria Novella | 6h42 | 6:35 PM Milan Centrale | 2 transfers | |
FRECCIAROSSA 1000 9514 | 11:55 AM Florence Santa Maria Novella | 1h55 | 1:50 PM Milan Centrale | 0 transfersDirect | |
FRECCIAROSSA 8418 · FRECCIAROSSA 1000 9632 | On time 12:20 PM Florence Santa Maria Novella | 2h15 | 2:35 PM Milan Centrale | 1 transfer | |
9928 | On time 12:25 PM Florence Santa Maria Novella | 1h55 | 2:20 PM Milan Centrale | 0 transfersDirect | |
Regionale 18373+ Intercity 680 | 12:53 PM Florence Santa Maria Novella | 6h07 | 7:00 PM Milan Centrale | 1 transfer | |
FRECCIAROSSA 9532 | 12:55 PM Florence Santa Maria Novella | 1h55 | 2:50 PM Milan Centrale | 0 transfersDirect | |
9932 | 1:25 PM Florence Santa Maria Novella | 1h55 | 3:20 PM Milan Centrale | 0 transfersDirect | |
Tuscany Line 18472 · Autobus TTPER B0442 · Regionale Veloce TTPER 2482 | 1:38 PM Florence Santa Maria Novella | 6h07 | 7:45 PM Milan Centrale | 2 transfers | |
Regionale 18377 · Regionale Veloce 3278 · Regionale Veloce 3044 | 1:53 PM Florence Santa Maria Novella | 6h42 | 8:35 PM Milan Centrale | 2 transfers | |
FRECCIAROSSA 9584 | 1:55 PM Florence Santa Maria Novella | 1h55 | 3:50 PM Milan Centrale | 0 transfersDirect | |
8134 | On time 2:25 PM Florence Santa Maria Novella | 1h55 | 4:20 PM Milan Centrale | 0 transfersDirect | |
FRECCIAROSSA 9540 | 2:55 PM Florence Santa Maria Novella | 1h55 | 4:50 PM Milan Centrale | 0 transfersDirect | |
9940 | 3:25 PM Florence Santa Maria Novella | 1h55 | 5:20 PM Milan Centrale | 0 transfersDirect | |
Regionale Veloce 4043+ Intercity 684 | 3:28 PM Florence Santa Maria Novella | 5h27 | 8:55 PM Milan Centrale | 1 transfer | |
Tuscany Line 18478 · Autobus TTPER B0444 · Regionale Veloce TTPER 2486 | 3:37 PM Florence Santa Maria Novella | 6h08 | 9:45 PM Milan Centrale | 2 transfers | |
Tuscany Line 18478 · Autobus TTPER B0444+ Intercity 612 | 3:37 PM Florence Santa Maria Novella | 5h03 | 8:40 PM Milan Centrale | 2 transfers | |
FRECCIAROSSA 9544 | On time 3:55 PM Florence Santa Maria Novella | 1h55 | 5:50 PM Milan Centrale | 0 transfersDirect | |
9946 | On time 4:25 PM Florence Santa Maria Novella | 1h55 | 6:20 PM Milan Centrale | 0 transfersDirect | |
ETRUSCHI LINE 18307 · Regionale 2596 | 4:28 PM Florence Santa Maria Novella | 5h54 | 10:22 PM Milan Centrale | 1 transfer | |
Tuscany Line 18480 · Autobus FI64V+ Intercity 614 | 4:37 PM Florence Santa Maria Novella | 6h08 | 10:45 PM Milan Centrale | 2 transfers | |
FRECCIAROSSA 9588 | 4:55 PM Florence Santa Maria Novella | 1h55 | 6:50 PM Milan Centrale | 0 transfersDirect | |
FRECCIAROSSA 9428 · FRECCIAROSSA 1000 9652 | 5:20 PM Florence Santa Maria Novella | 2h10 | 7:30 PM Milan Centrale | 1 transfer | |
9948 | 5:25 PM Florence Santa Maria Novella | 1h55 | 7:20 PM Milan Centrale | 0 transfersDirect | |
FRECCIAROSSA 9552 | 5:55 PM Florence Santa Maria Novella | 1h55 | 7:50 PM Milan Centrale | 0 transfersDirect | |
FRECCIAROSSA 1000 9430 · FRECCIAROSSA 1000 9660 | 6:20 PM Florence Santa Maria Novella | 2h10 | 8:30 PM Milan Centrale | 1 transfer | |
9958 | On time 6:25 PM Florence Santa Maria Novella | 1h55 | 8:20 PM Milan Centrale | 0 transfersDirect | |
TUSCANY LINE 18484 · Autobus FI66V+ Intercity 1526 | 6:37 PM Florence Santa Maria Novella | 4h53 | 11:30 PM Milan Centrale | 2 transfers | |
FRECCIAROSSA 1000 9556 | 6:55 PM Florence Santa Maria Novella | 1h55 | 8:50 PM Milan Centrale | 0 transfersDirect | |
9954 | 7:25 PM Florence Santa Maria Novella | 1h55 | 9:20 PM Milan Centrale | 0 transfersDirect | |
FRECCIAROSSA 1000 9560 | 7:55 PM Florence Santa Maria Novella | 1h55 | 9:50 PM Milan Centrale | 0 transfersDirect | |
FRECCIAROSSA 1000 9434 · FRECCIAROSSA 8830 | 8:20 PM Florence Santa Maria Novella | 2h10 | 10:30 PM Milan Centrale | 1 transfer | |
8158 | 8:25 PM Florence Santa Maria Novella | 1h55 | 10:20 PM Milan Centrale | 0 transfersDirect | |
FRECCIAROSSA 1000 9330 | 8:36 PM Florence Santa Maria Novella | 2h49 | 11:25 PM Milan Centrale | 0 transfersDirect | |
FRECCIAROSSA 9592 | 8:55 PM Florence Santa Maria Novella | 1h55 | 10:50 PM Milan Centrale | 0 transfersDirect | |
9962 | 9:25 PM Florence Santa Maria Novella | 1h55 | 11:20 PM Milan Centrale | 0 transfersDirect | |
Regionale 18253+ Intercity 662 | 3:30 AM Florence Santa Maria Novella | 6h25 | 9:55 AM Milan Centrale | 1 transfer | |
Regionale 17800 · Autobus FI76V · Regionale Veloce TTPER 2460 | 3:32 AM Florence Santa Maria Novella | 5h13 | 8:45 AM Milan Centrale | 2 transfers | |
This is the last train of the day. | |||||
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Compare prices and tickets Florence Santa Maria Novella to Milan Centrale by bus, train, or flight
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Journey information
Overview: Train from Florence Santa Maria Novella to Milan Centrale
Trains from Florence Santa Maria Novella to Milan Centrale run on average 37 times per day, taking around 3h 40m. Cheap train tickets for this journey start at €26 but you can travel from only €9 by bus.
There are 21 trains per day. The earliest train runs at 04:38, the last at 20:25. The fastest train covers the 250 km distance in 1h 55m.
Distance 250 km |
Average train duration 3h 40m |
Cheapest ticket price €26 |
Trains per day 37 |
Direct trains 21 |
Fastest train 1h 55m |
First train 04:38 |
Last train 20:25 |
Train companies: Italo, Frecciarossa, Intercity, Regionale, Intercity Notte from Florence Santa Maria Novella to Milan Centrale trainsItalo, Frecciarossa, Intercity, Regionale, Intercity Notte trains will get you between Florence Santa Maria Novella and Milan Centrale from €9. With over 1000 travel companies on Omio, you can find the best train times and tickets for your trip.
Italo
Frecciarossa
Intercity
Regionale
Intercity Notte
FAQs: Trains from Florence Santa Maria Novella to Milan Centrale
Find answers to the most common questions about traveling from Florence Santa Maria Novella to Milan Centrale by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Milan Centrale, this guide helps you travel smarter and with confidence.

popular train stations
Popular train stations from Florence Santa Maria Novella to Milan Centrale
- Mon - Sun: 06:00 - 21:00
- Free WiFi (30 minutes limit).
- Provided by KiPoint and located on the ground floor, on the side of Piazza Adua. Open daily from 06:00 to 23:00.
- 12oz Coffee Joint
- Casa Maioli
- Don Nino
- Fratelli Cuore
- McDonald´s
- Panella
- Segafredo Zanetti
- Spizzico
- Venchi
- & many more
- Elevators, escalators, step-free access. Mobility assistance is available with the Sala Blu, located next to Platform 1.
- Hotel Luxor Florence
- Joy Hotel Florence
- Diplomat Hotel Florence
- Mon - Sun: 06:00 - 21:00
- Located inside and outside the station.
- Tram lines: T1, T2
- Bus lines: 6, 11, 12, 13, 17, 23, 36, 37, C4
- Train lines: FR, FA, Italo
- Mon - Sun: 05:50 - 22:20
- Free WiFi in the station.
- Provided by KiPoint and located on the ground floor, on the side of Piazza Luigi di Savoia. It is open every day from 06:00 to 23:00.
- Venchi
- Panzera Coffee
- Burger King
- Bar Motta
- Caffè Napoli
- VyTA Boulangerie
- Spontini
- Starbucks
- Dispensa Emilia
- McDonald's
- & many more
- Station is wheelchair accessible, has elevators and the Sala Blu, Trenitalia's office of assistance for disabled travelers, is next to Platform 4.
- Glam Hotel Milano
- NYX MIlan
- iQ Hotel Milano
- Mon - Sun: 05:50 - 22:20
- Located next to the ticket office on the ground floor in the shopping gallery.
- Metro lines: M2 (green), M3 (yellow)
- Tram lines: 1
- Bus lines: 5, 9, 10, 42, 81, 87, 152, 728, N26, NM2, NM3, Air Bus, Orio Shuttle
- Train lines: FR, FB, EC, Thello, XP2, R28, IC, ICN, RV, R, Regio, Italo
Most popular train connections from Florence Santa Maria Novella
More options for your journey from Florence Santa Maria Novella to Milan Centrale
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