The cheapest and fastest trains from Florence Santa Maria Novella to Milan Centrale
Cheapest price
€26
Average price
€58
Fastest journey
1 h 55 m
Average duration
1 h 55 m
Trains per day
60
Distance
250 km
The best way to find a cheap train ticket from Florence Santa Maria Novella to Milan Centrale is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Florence Santa Maria Novella to Milan Centrale will cost around €58 if you buy it on the day, but the cheapest tickets can be found for only €26.
Of the 60 trains that leave Florence Santa Maria Novella for Milan Centrale on Tue, May 12, 30 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Tue, May 12 the direct trains cover the 250 km distance in an average of 1 h 55 m but if you time it right, some trains will get you there in just 1 h 55 m .
On Tue, May 12 the slowest trains will take 1 h 55 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
Regionale 18654 · Regionale 17804 · Regionale Veloce TTPER 24625:41 AM5h04Florence Santa Maria Novella10:45 AMMilan Centrale€261One-way2 transfers
Regionale 18466 · Regionale 17816 · Regionale Veloce TTPER 24708:37 AM6h08Florence Santa Maria Novella2:45 PMMilan Centrale€261One-way2 transfers
Regionale 17800 · Regionale Veloce TTPER 24604:32 AM5h13Florence Santa Maria Novella9:45 AMMilan Centrale€261One-way1 transfer
Regionale 18664 · Autobus TTPER B0400 · Regionale Veloce TTPER 247410:20 AM6h25Florence Santa Maria Novella4:45 PMMilan Centrale€261One-way2 transfers
Regionale 18494 · Regionale 17830 · Regionale Veloce TTPER 24781:37 PM5h08Florence Santa Maria Novella6:45 PMMilan Centrale€261One-way2 transfers
FRECCIAROSSA 95885:55 PM1h55Florence Santa Maria Novella7:50 PMMilan Centrale€671One-way0 transfers
99486:25 PM1h55Florence Santa Maria Novella8:20 PMMilan Centrale€571One-way0 transfers
FRECCIAROSSA 95842:55 PM1h55Florence Santa Maria Novella4:50 PMMilan Centrale€671One-way0 transfers
FRECCIAROSSA 95321:55 PM1h55Florence Santa Maria Novella3:50 PMMilan Centrale€611One-way0 transfers
FRECCIAROSSA 95444:55 PM1h55Florence Santa Maria Novella6:50 PMMilan Centrale€611One-way0 transfers
Travel Information
Compare bus, train, and flight for Florence Santa Maria Novella to Milan Centrale
Omio recommends booking the train as it is the most popular option from Florence Santa Maria Novella to Milan Centrale among Omio's users. If you are prioritising price take the bus with prices starting from €8. For those with little time consider booking a train which can get you there in 3h 40m. The ticket price range depends on the travel mode: a bus costs an average of €8, and a flight costs an average of €104.
Distance: 250 km
Compare train with
Most popular Train | Bus | Flight |
|---|---|---|
€35 Average price | €18 Average price Cheapest | €104 Average price |
4h 10m Average total duration Fastest 3h 40m Onboard + 30m Additional time* | 4h 39m Average total duration 4h 9m Onboard + 30m Additional time* | 9h 38m Average total duration 6h 38m Onboard + 3h 0m Additional time* |
Direct Options | Direct Options | Direct Options |
Live departures
Florence Santa Maria Novella to Milan Centrale train times
The table below shows live departures for Florence Santa Maria Novella to Milan Centrale trains for today, Monday, May 11. You can also manually refresh the results below to see updated train journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
9940 | Delayed 2:36 PM 4:25 PMFlorence Santa Maria Novella | 1h55 | 6:20 PM Milan Centrale | 0 transfersDirect | |
Regionale Veloce 4043+ Intercity 684 | 4:28 PM Florence Santa Maria Novella | 5h27 | 9:55 PM Milan Centrale | 1 transfer | |
FRECCIAROSSA 9544 | 4:55 PM Florence Santa Maria Novella | 1h55 | 6:50 PM Milan Centrale | 0 transfersDirect | |
Regionale 18524 · Regionale 17838 · Regionale Veloce TTPER 2486 | 5:09 PM Florence Santa Maria Novella | 5h36 | 10:45 PM Milan Centrale | 2 transfers | |
9946 | Delayed 3:29 PM 5:25 PMFlorence Santa Maria Novella | 1h55 | 5:24 PM 5:24 PMMilan Centrale | 0 transfersDirect | |
FRECCIAROSSA 9588 | 5:55 PM Florence Santa Maria Novella | 1h55 | 7:50 PM Milan Centrale | 0 transfersDirect | |
FRECCIAROSSA 9428 · FRECCIAROSSA 9652 | 6:20 PM Florence Santa Maria Novella | 2h10 | 8:30 PM Milan Centrale | 1 transfer | |
9948 | Delayed 4:37 PM 6:25 PMFlorence Santa Maria Novella | 1h55 | 8:20 PM Milan Centrale | 0 transfersDirect | |
FRECCIAROSSA 9552 | 6:55 PM Florence Santa Maria Novella | 1h55 | 8:50 PM Milan Centrale | 0 transfersDirect | |
Regionale 18227+ Intercity 596 | 7:10 PM Florence Santa Maria Novella | 4h07 | 11:17 PM Milan Centrale | 1 transfer | |
FRECCIAROSSA 9430 · FRECCIAROSSA 9660 | 7:20 PM Florence Santa Maria Novella | 2h10 | 9:30 PM Milan Centrale | 1 transfer | |
9958 | 7:25 PM Florence Santa Maria Novella | 1h55 | 9:20 PM Milan Centrale | 0 transfersDirect | |
FRECCIAROSSA 9556 | 7:55 PM Florence Santa Maria Novella | 1h55 | 9:50 PM Milan Centrale | 0 transfersDirect | |
9954 | On time 8:25 PM Florence Santa Maria Novella | 1h55 | 10:20 PM Milan Centrale | 0 transfersDirect | |
FRECCIAROSSA 9560 | 8:55 PM Florence Santa Maria Novella | 1h55 | 10:50 PM Milan Centrale | 0 transfersDirect | |
FRECCIAROSSA 9434 · FRECCIAROSSA 8830 | 9:20 PM Florence Santa Maria Novella | 2h05 | 11:25 PM Milan Centrale | 1 transfer | |
8158 | 9:25 PM Florence Santa Maria Novella | 1h55 | 11:20 PM Milan Centrale | 0 transfersDirect | |
FRECCIAROSSA 9330 | 9:36 PM Florence Santa Maria Novella | 2h49 | 12:25 AM Milan Centrale | 0 transfersDirect | |
FRECCIAROSSA 9592 | 9:55 PM Florence Santa Maria Novella | 1h55 | 11:50 PM Milan Centrale | 0 transfersDirect | |
9962 | 10:25 PM Florence Santa Maria Novella | 1h55 | 12:20 AM Milan Centrale | 0 transfersDirect | |
Regionale 18805+ InterCityNotte 774 · InterCityNotte 758 | 11:18 PM Florence Santa Maria Novella | 7h47 | 7:05 AM Milan Centrale | 2 transfers | |
| Tuesday, May 12 | |||||
Treno 18251 effettuato con bus FI653+ InterCityNotte 37278+ Regionale Veloce 3019 | 12:40 AM Florence Santa Maria Novella | 8h55 | 9:35 AM Milan Centrale | 2 transfers | |
Regionale 17800 · Regionale Veloce TTPER 2460 | 4:32 AM Florence Santa Maria Novella | 5h13 | 9:45 AM Milan Centrale | 1 transfer | |
Regionale 18654 · Regionale 17804 · Regionale Veloce TTPER 2462 | 5:41 AM Florence Santa Maria Novella | 5h04 | 10:45 AM Milan Centrale | 2 transfers | |
Regionale 18502 · Regionale 17808 · Regionale Veloce TTPER 2466 | 7:09 AM Florence Santa Maria Novella | 5h36 | 12:45 PM Milan Centrale | 2 transfers | |
FRECCIAROSSA 9400 · FRECCIAROSSA 9802 | 7:20 AM Florence Santa Maria Novella | 2h15 | 9:35 AM Milan Centrale | 1 transfer | |
FRECCIAROSSA 9404 · FRECCIAROSSA 9610 | 8:20 AM Florence Santa Maria Novella | 2h15 | 10:35 AM Milan Centrale | 1 transfer | |
Intercity 580 | 8:21 AM Florence Santa Maria Novella | 3h54 | 12:15 PM Milan Centrale | 0 transfersDirect | |
Regionale 18466 · Regionale 17816 · Regionale Veloce TTPER 2470 | 8:37 AM Florence Santa Maria Novella | 6h08 | 2:45 PM Milan Centrale | 2 transfers | |
Regionale 18466 · Regionale 17816+ Intercity 604 | 8:37 AM Florence Santa Maria Novella | 5h03 | 1:40 PM Milan Centrale | 2 transfers | |
FRECCIAROSSA 9512 | 8:55 AM Florence Santa Maria Novella | 1h55 | 10:50 AM Milan Centrale | 0 transfersDirect | |
Regionale 18508 · Autobus FI680+ Intercity 606 | 9:09 AM Florence Santa Maria Novella | 6h21 | 3:30 PM Milan Centrale | 2 transfers | |
FRECCIAROSSA 9406 · FRECCIAROSSA 9616 | 9:20 AM Florence Santa Maria Novella | 2h15 | 11:35 AM Milan Centrale | 1 transfer | |
9912 | On time 9:25 AM Florence Santa Maria Novella | 1h55 | 11:20 AM Milan Centrale | 0 transfersDirect | |
Regionale 18361+ Intercity 670 | 9:53 AM Florence Santa Maria Novella | 6h02 | 3:55 PM Milan Centrale | 1 transfer | |
FRECCIAROSSA 9516 | 9:55 AM Florence Santa Maria Novella | 1h55 | 11:50 AM Milan Centrale | 0 transfersDirect | |
Regionale 18664 · Autobus TTPER B0400 · Regionale Veloce TTPER 2474 | 10:20 AM Florence Santa Maria Novella | 6h25 | 4:45 PM Milan Centrale | 2 transfers | |
FRECCIAROSSA 9490 · FRECCIAROSSA 8810 | 10:20 AM Florence Santa Maria Novella | 2h10 | 12:30 PM Milan Centrale | 1 transfer | |
9916 | On time 10:25 AM Florence Santa Maria Novella | 1h55 | 12:20 PM Milan Centrale | 0 transfersDirect | |
FRECCIAROSSA 9520 | 10:55 AM Florence Santa Maria Novella | 1h55 | 12:50 PM Milan Centrale | 0 transfersDirect | |
FRECCIAROSSA 9414 · FRECCIAROSSA 9806 | 11:20 AM Florence Santa Maria Novella | 2h05 | 1:25 PM Milan Centrale | 1 transfer | |
9920 | On time 11:25 AM Florence Santa Maria Novella | 1h55 | 1:20 PM Milan Centrale | 0 transfersDirect | |
Regionale 94455+ Intercity 608 | 11:40 AM Florence Santa Maria Novella | 6h05 | 5:45 PM Milan Centrale | 1 transfer | |
FRECCIAROSSA 9524 | 11:55 AM Florence Santa Maria Novella | 1h55 | 1:50 PM Milan Centrale | 0 transfersDirect | |
FRECCIAROSSA 9416 · FRECCIAROSSA 8814 | 12:20 PM Florence Santa Maria Novella | 2h05 | 2:25 PM Milan Centrale | 1 transfer | |
9924 | On time 12:25 PM Florence Santa Maria Novella | 1h55 | 2:20 PM Milan Centrale | 0 transfersDirect | |
Regionale Veloce 4029+ Intercity 674 | 12:28 PM Florence Santa Maria Novella | 5h27 | 5:55 PM Milan Centrale | 1 transfer | |
FRECCIAROSSA 9514 | 12:55 PM Florence Santa Maria Novella | 1h55 | 2:50 PM Milan Centrale | 0 transfersDirect | |
Regionale 18293+ Intercity 588 · Intercity 608 | 1:16 PM Florence Santa Maria Novella | 4h29 | 5:45 PM Milan Centrale | 2 transfers | |
FRECCIAROSSA 8418 · FRECCIAROSSA 9632 | 1:20 PM Florence Santa Maria Novella | 2h15 | 3:35 PM Milan Centrale | 1 transfer | |
9928 | 1:25 PM Florence Santa Maria Novella | 1h55 | 3:20 PM Milan Centrale | 0 transfersDirect | |
Regionale 18494 · Regionale 17830 · Regionale Veloce TTPER 2478 | 1:37 PM Florence Santa Maria Novella | 5h08 | 6:45 PM Milan Centrale | 2 transfers | |
FRECCIAROSSA 9532 | 1:55 PM Florence Santa Maria Novella | 1h55 | 3:50 PM Milan Centrale | 0 transfersDirect | |
9932 | On time 2:25 PM Florence Santa Maria Novella | 1h55 | 4:20 PM Milan Centrale | 0 transfersDirect | |
FRECCIAROSSA 9584 | 2:55 PM Florence Santa Maria Novella | 1h55 | 4:50 PM Milan Centrale | 0 transfersDirect | |
Regionale 18520 · Regionale 17834 · Regionale Veloce TTPER 2482 | 3:09 PM Florence Santa Maria Novella | 5h36 | 8:45 PM Milan Centrale | 2 transfers | |
Regionale 18219+ Intercity 590 | 3:10 PM Florence Santa Maria Novella | 4h15 | 7:25 PM Milan Centrale | 1 transfer | |
8134 | On time 3:25 PM Florence Santa Maria Novella | 1h55 | 5:20 PM Milan Centrale | 0 transfersDirect | |
FRECCIAROSSA 9540 | 3:55 PM Florence Santa Maria Novella | 1h55 | 5:50 PM Milan Centrale | 0 transfersDirect | |
Regionale 18522 · Regionale 17836+ Intercity 612 | 4:09 PM Florence Santa Maria Novella | 5h31 | 9:40 PM Milan Centrale | 2 transfers | |
Find all the dates and times for this journey
Compare prices and tickets Florence Santa Maria Novella to Milan Centrale by bus, train, or flight
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Why should you book Florence Santa Maria Novella to Milan Centrale trains with Omio?
Why book with Omio vs Italo?
- Compare with other providers: On Omio, you can not only buy tickets for Italo, but also compare tickets for the likes of Frecciarossa, Intercity, Regionale or Intercity Notte to find the best option for your trip from Florence Santa Maria Novella to Milan Centrale.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Italo with all available travel options, which are bus, train and flight to ensure you get the best deal for traveling from Florence Santa Maria Novella to Milan Centrale.
Journey information
Overview: Train from Florence Santa Maria Novella to Milan Centrale
Trains from Florence Santa Maria Novella to Milan Centrale run on average 43 times per day, taking around 3h 40m. Cheap train tickets for this journey start at €18 but you can travel from only €8 by bus.
There are 24 trains per day. The earliest train runs at 02:32, the last at 22:18. The fastest train covers the 250 km distance in 1h 55m.
Distance 250 km |
Average train duration 3h 40m |
Cheapest ticket price €18 |
Trains per day 43 |
Direct trains 24 |
Fastest train 1h 55m |
First train 2:32 AM |
Last train 10:18 PM |
Cheapest Month Nov |
Cheapest Day Sat |
High Season Apr - Jun |
Low Season Jan - Mar |
Busiest Day Mon |
Least Busy Day Sat |
Train companies: Italo, Frecciarossa, Intercity, Regionale, Intercity Notte from Florence Santa Maria Novella to Milan Centrale trainsItalo, Frecciarossa, Intercity, Regionale, Intercity Notte trains will get you between Florence Santa Maria Novella and Milan Centrale from €8. With over 1000 travel companies on Omio, you can find the best train times and tickets for your trip.
Italo
Frecciarossa
Intercity
Regionale
Intercity Notte
FAQs: Trains from Florence Santa Maria Novella to Milan Centrale
Find answers to the most common questions about traveling from Florence Santa Maria Novella to Milan Centrale by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Milan Centrale, this guide helps you travel smarter and with confidence.

popular train stations
Popular train stations from Florence Santa Maria Novella to Milan Centrale
- Mon - Sun: 06:00 - 21:00
- Free WiFi (30 minutes limit).
- Provided by KiPoint and located on the ground floor, on the side of Piazza Adua. Open daily from 06:00 to 23:00.
- 12oz Coffee Joint
- Casa Maioli
- Don Nino
- Fratelli Cuore
- McDonald´s
- Panella
- Segafredo Zanetti
- Spizzico
- Venchi
- & many more
- Elevators, escalators, step-free access. Mobility assistance is available with the Sala Blu, located next to Platform 1.
- Hotel Luxor Florence
- Joy Hotel Florence
- Diplomat Hotel Florence
- Mon - Sun: 06:00 - 21:00
- Located inside and outside the station.
- Tram lines: T1, T2
- Bus lines: 6, 11, 12, 13, 17, 23, 36, 37, C4
- Train lines: FR, FA, Italo
- Mon - Sun: 05:50 - 22:20
- Free WiFi in the station.
- Provided by KiPoint and located on the ground floor, on the side of Piazza Luigi di Savoia. It is open every day from 06:00 to 23:00.
- Venchi
- Panzera Coffee
- Burger King
- Bar Motta
- Caffè Napoli
- VyTA Boulangerie
- Spontini
- Starbucks
- Dispensa Emilia
- McDonald's
- & many more
- Station is wheelchair accessible, has elevators and the Sala Blu, Trenitalia's office of assistance for disabled travelers, is next to Platform 4.
- Glam Hotel Milano
- NYX MIlan
- iQ Hotel Milano
- Mon - Sun: 05:50 - 22:20
- Located next to the ticket office on the ground floor in the shopping gallery.
- Metro lines: M2 (green), M3 (yellow)
- Tram lines: 1
- Bus lines: 5, 9, 10, 42, 81, 87, 152, 728, N26, NM2, NM3, Air Bus, Orio Shuttle
- Train lines: FR, FB, EC, Thello, XP2, R28, IC, ICN, RV, R, Regio, Italo
Most popular train connections from Florence Santa Maria Novella
More options for your journey from Florence Santa Maria Novella to Milan Centrale
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