Prague to Brussels train with Deutsche Bahn (ICE,EC,IC,RE,RB)

Wed, Nov 19
+ Add return
Deutsche Bahn
European Sleeper
European Sleeper
Regionale
SNCF TER
1,000+ travel companies
Deutsche Bahn
European Sleeper
European Sleeper
Regionale
SNCF TER
1,000+ travel companies
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The cheapest and fastest trains from Prague to Brussels

Showing times and prices for Nov 19

Cheapest price

€104

Average price

€252

Fastest journey

10 h 58 m

Average duration

11 h 3 m

Trains per day

17

Distance

717 km

Cheap tickets

The best way to find a cheap train ticket from Prague to Brussels is to book your journey as far in advance as possible and to avoid traveling at rush hour.

The average ticket from Prague to Brussels will cost around €252 if you buy it on the day, but the cheapest tickets can be found for only €104.

Fast trains

It's difficult to get from Prague to Brussels without transferring at least 3 times.

České dráhyEC 176 · IC 2440 · ICE 795 · ICE 12
08:28AM10h58
Prague hlavní nádraží
07:26PMBrussels-North
1041One-way
3 transfers
České dráhyEC 176 · IC 2440 · ICE 795 · ICE 12
08:28AM11h06
Prague hlavní nádraží
07:34PMBrussels-Central
1361One-way
4 transfers
České dráhyEC 176 · IC 2440 · ICE 795 · ICE 12
08:28AM11h21
Prague hlavní nádraží
07:49PMBrussels Congress
1361One-way
4 transfers
Deutsche BahnEC 174 · IC 2442 · ICE 797 · ICE 10
10:28AM11h07
Prague hlavní nádraží
09:35PMBrussels-Midi
1911One-way
3 transfers
Deutsche BahnEC 176 · IC 2440 · ICE 795 · ICE 12
08:28AM11h07
Prague hlavní nádraží
07:35PMBrussels-Midi
1911One-way
3 transfers

Travel Information

Compare train, bus, and flight for Prague to Brussels

Omio recommends booking the flight as it is the most popular option from Prague to Brussels among Omio's users. If you are prioritising price take the bus with prices starting from €27. For those with little time consider booking a flight which can get you there in 2h 27m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.2 - 0.6kg. The ticket price range depends on the travel mode: a bus costs an average of €27, and a flight costs an average of €34.

Distance: 717 km

Compare train with

Train
Most popular
Flight
Bus

€161

Average price

€192

Average price

€66

Average price

Cheapest

13h 42m

Average total duration

13h 12m

Onboard

+

30m

Additional time*

5h 27m

Average total duration

Fastest

2h 27m

Onboard

+

3h 0m

Additional time*

14h 9m

Average total duration

13h 39m

Onboard

+

30m

Additional time*

0.2 - 0.6kg

CO2 emissions

Lowest

2.2 - 4.3kg

CO2 emissions

0.7 - 1.8kg

CO2 emissions

Deutsche Bahn

Most popular train company

Ryanair

Most popular airline

FlixBus

Most popular bus company

Direct Options

Direct Options

Direct Options

Additional time: Average total travel duration to departure point, security checks and transfers.

Live departures

Prague to Brussels train times

The table below shows live departures for Prague to Brussels trains for tomorrow, Wednesday, November 19. You can also manually refresh the results below to see updated train journeys.

Last updated at 8:51 PM
ProviderDepartsDurationArrivesTransfers
Tickets
czechrailwayEC 176 · IC 2440 · ICE 795 · ICE 12
On time
7:28 AM Prague hlavní nádraží
11h06
6:34 PM Brussels-Central
4 transfers
czechrailwayEC 176 · IC 2440 · ICE 795 · ICE 12
On time
7:28 AM Prague hlavní nádraží
11h21
6:49 PM Brussels Congress
4 transfers
czechrailwayEC 176 · IC 2440 · ICE 795 · ICE 12
On time
7:28 AM Prague hlavní nádraží
10h58
6:26 PM Brussels-North
3 transfers
deutsche_bahnEC 176 · IC 2440 · ICE 795 · ICE 12
On time
7:28 AM Prague hlavní nádraží
11h07
6:35 PM Brussels-Midi
3 transfers
czechrailwayEC 358 · ICE 26 · ICE 10 · R 39928:35 AM Prague hlavní nádraží
12h09
8:44 PM Brussels Congress4 transfers
czechrailwayEC 358 · ICE 26 · ICE 10 · R 19938:35 AM Prague hlavní nádraží
12h40
9:15 PM Brussels Congress3 transfers
czechrailwayEC 358 · ICE 26 · ICE 10 · R 39928:35 AM Prague hlavní nádraží
11h59
8:34 PM Brussels-Central3 transfers
deutsche_bahnEX 358 · ICE 26 · ICE 10
On time
8:35 AM Prague hlavní nádraží
12h00
8:35 PM Brussels-Midi
2 transfers
czechrailwayEC 358 · ICE 26 · ICE 10
On time
8:35 AM Prague hlavní nádraží
11h51
8:26 PM Brussels-North
2 transfers
deutsche_bahnEC 174 · IC 2442 · ICE 797 · ICE 10
On time
9:28 AM Prague hlavní nádraží
11h07
8:35 PM Brussels-Midi
3 transfers
czechrailwayEC 174 · IC 2442 · ICE 797 · ICE 10
On time
9:28 AM Prague hlavní nádraží
10h58
8:26 PM Brussels-North
3 transfers
czechrailwayEC 174 · IC 2442 · ICE 797 · ICE 10
On time
9:28 AM Prague hlavní nádraží
11h47
9:15 PM Brussels Congress
4 transfers
czechrailwayEC 174 · IC 2442 · ICE 797 · ICE 10
On time
9:28 AM Prague hlavní nádraží
11h06
8:34 PM Brussels-Central
4 transfers
deutsche_bahnEC 378 · ICE 844 · RE 26436 · RE 18978
On time
11:33 AM Prague hlavní nádraží
17h14
4:47 AM Brussels-Midi
4 transfers
deutsche_bahnEX 354 · RE 3576 · ICE 526 · RE 26438
On time
12:35 PM Prague hlavní nádraží
18h30
7:05 AM Brussels-Midi
7 transfers
czechrailwayEC 458 · ICE 699 · ICE 18 · R 39805:28 PM Prague hlavní nádraží
15h06
8:34 AM Brussels-Central3 transfers
czechrailwayEC 458 · ICE 699 · ICE 185:28 PM Prague hlavní nádraží
14h58
8:26 AM Brussels-North2 transfers

This is the last train of the day.

Find all the dates and times for this journey

Compare prices and tickets Prague to Brussels by train, bus, or flight

Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.

Wed
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Dec 09

How far in advance should I book train tickets from Prague to Brussels?

The best time to book your train from Prague to Brussels is 77 days before departure. See how prices for trains change on the Prague to Brussels route.
Prices are for one-way tickets for one passenger from Prague to Brussels per month. Insights are sourced from fares found by Omio users in the last 12 months. Current prices may differ as prices vary depending on the time of day, class or how far in advance you book your train from Prague to Brussels.

Journey information

Overview: Train from Prague to Brussels

CzechiaCzechia
BelgiumBelgium
Icon of train

Trains from Prague to Brussels run on average 5 times per day, taking around 13h 12m. Cheap train tickets for this journey start at €88 but you can travel from only €27 by bus.

The earliest train runs at 00:10, the last at 23:50. The fastest train covers the 717 km distance in 10h 55m.

Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Bus from €27
Distance
717 km
Average train duration
13h 12m
Cheapest ticket price
€88
Trains per day
5
Fastest train
10h 55m
First train
00:10
Last train
23:50
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Bus from €27

Train companies: Deutsche Bahn, European Sleeper from Prague to Brussels trainsDeutsche Bahn, European Sleeper trains will get you between Prague and Brussels from €27. With over 1000 travel companies on Omio, you can find the best train times and tickets for your trip.

Deutsche Bahn

About
Deutsche Bahn (DB) is Germany’s main train operator, running around 40,000 domestic and international services each day. Its fleet includes a variety of train types: high-speed ICE (Intercity Express) trains, reaching up to 300 km/h; IC (Intercity) and EC (EuroCity) trains for long-distance travel; and IRE (Interregio-Express), RE (Regional Express), and RB (Regionalbahn) services for regional and local connections. While bathrooms are standard on all trains, amenities such as onboard restaurants and free Wi-Fi are available only on certain train types and routes. DB offers a wide range of fares, including Super Saver, Saver, and Flexible tickets, along with discount cards like the BahnCard 25, 50, and 100. Additional options include single tickets, day tickets, and group tickets. Popular routes include Berlin–Munich, Hamburg–Frankfurt, Cologne–Stuttgart, Berlin–Dresden, and Hamburg–Cologne, as well as numerous regional services across Germany.
Luggage & cancellation policy
Average Duration
10h 55m
Cheapest Price
€100
Deutsche Bahn frequency
4 a day
Luggage included
Passengers are allowed to bring hand luggage and one additional larger item free of charge, provided they can carry it themselves
Luggage storage
Luggage can be stored in overhead racks, under the seat, or in designated luggage areas near the doors or in the middle of the carriage.
Cancellation Policy
Tickets can be canceled based on their fare conditions as mentioned in what type of train tickets are refundable?
Refund
If DB cancels a train, passengers are entitled to a full refund of the ticket price.
Amenities on board the train
Wifi
Food sold onboard
Most ICE and many IC/EC trains have:
A Bordrestaurant (restaurant car) where you can sit and eat.
A Bordbistro (bistro bar) with snacks, hot meals, and drinks to-go.
At-seat service in 1st class: staff will take your order and serve food/drinks directly to your seat.
Regional trains (RE / RB / S-Bahn):
No onboard catering.
You’re welcome to bring your own food and drinks.
Seat reservation
Second Class:
Not included by default.
You can add a seat reservation when booking (recommended for busy routes).
Costs around €4.90 per seat (or €5.90 if booked separately later).
First Class:
Yes, always included in the ticket price.
Toilets
USB plugs
Accessibility
DB trains are equipped with facilities for passengers with reduced mobility, including wheelchair spaces, accessible restrooms, and assistance services.
Pets
Small pets (e.g. cats, small dogs, etc.):
Allowed for free if they can fit in a transport box (max. size: hand luggage).
Must stay in the box for the entire journey.
Large dogs:
Require a separate (paid) ticket — typically half the price of a regular second-class ticket.
Must be leashed and wear a muzzle while on the train.
Cannot sit on seats.
Assistance dogs:
Travel free of charge.
Do not need a muzzle or leash if medically not required.
Allowed to accompany the passenger at all times.
Quiet zone

European Sleeper

About
European Sleeper is a Belgian-Dutch train company launched in 2021, operating night train services between Germany and Belgium three times a week, with plans to expand to daily service and extend routes to cities such as Dresden and Prague. Passengers can choose from standard seats, couchettes, or sleeper cabins. Couchettes include free drinks and power outlets, while sleeper cabins offer power outlets and complimentary meals. All tickets are sold as Flex Night fares, which are non-exchangeable but can be canceled up to 48 hours before departure.
Luggage & cancellation policy
Average Duration
15h 25m
Cheapest Price
€50
European Sleeper frequency
1 a day
Luggage included
1 piece of hand luggage and 2 pieces of hold luggage included in ticket price
Luggage storage
Luggage racks above seats and at end of carriages
Cancellation Policy
Cancellation possible according to fare conditions
Refund
Full refund provided for canceled trains
Amenities on board the train
Wifi
Food sold onboard
Restaurant car serving breakfast, drinks and snacks available for purchase
Seat reservation
Seat or berth reservation mandatory and included in ticket price
Toilets
USB plugs
Accessibility
Wheelchair spaces available, accessible toilets, staff assistance
Pets
Small pets in carriers allowed for free, larger dogs require paid ticket
Quiet zone

FAQs: Trains from Prague to Brussels

Find answers to the most common questions about traveling from Prague to Brussels by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Brussels, this guide helps you travel smarter and with confidence.

FAQs
Cheap train tickets from Prague to Brussels can start from as little as €49 when you book in advance. The average train ticket price for Prague to Brussels is €117; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The train time to Brussels from Prague is on average 11 h 7 min   for the 717 km long journey, but the time it takes to go to Brussels from Prague by train can vary depending on specific dates or if traveling on weekends and holidays.
The first train from Prague to Brussels leaves at 00: 20. Plan your trip with the Journey Planner   from Omio.
The last train from Prague to Brussels leaves at 23: 25.
There are 7 trains a day from Prague to Brussels which require at least one change with Deutsche Bahn or European Sleeper. Schedules can vary on holidays or weekends with fewer trains.
For the best Prague to Brussels train to book, you can travel safely and comfortably with Deutsche Bahn or European Sleeper. However, it's always good to check all possible train companies with services between Prague and Brussels to compare what amenities they may offer.
Yes, you can take a night train from Prague to Brussels with European Sleeper. Find all the info regarding night trains in Europe.  
The cheapest month for a train from Prague to Brussels is April.
You have options as you can travel from Prague to Brussels 3 different ways: coach, train or flight.

popular train stations

Popular train stations from Prague to Brussels

Prague
Brussels
The major train station for departures in Prague is Praha-Holesovice. Find all the information you need to know about services, amenities and connections at Praha-Holesovice for your trip from Prague to Brussels.
Praha-HolesoviceWifiLockersParkingDiningATMTaxisAccessibilityWCHotelLost and Found OfficeTicket OfficeBike ParkingBike RentalCar RentalInformation DeskLuggage Carts
Amenities at train station
WifiWifi
LockersLockers
ParkingParking
DiningDining
ATMATM
TaxisTaxis
AccessibilityAccessibility
WCWC
HotelHotel
Lost and Found OfficeLost and Found Office
Ticket OfficeTicket Office
Bike ParkingBike Parking
Bike RentalBike Rental
Car RentalCar Rental
Information DeskInformation Desk
Luggage CartsLuggage Carts
information
phone
Phone Number
ticketOfficeHours
Ticket Office Hours
  • 6:00 AM - 10:00 PM Monday - Sunday
ticketOfficeHours
Distance to city center
2 km
platformCount
Number of platforms
4
Wifi
Wifi
  • Free
Parking
Parking
  • Parking is available 24/7 with access from Partyzánská street.
Dining
Dining
  • Restaurant Na Kovárně
  • Cross Club
Taxis
Taxis
  • Outside the main entrance.
Accessibility
Accessibility
  • Ramps, restrooms.
WC
WC
  • CZK 10
Hotel
Hotel
  • Mama Shelter Prague
  • Plaza Alta Hotel
  • Hotel Belvedere
Lost and Found Office
Lost and Found Office
  • Located in the main hall
Car Rental
Car Rental
  • Avis
  • Budget
Information Desk
Information Desk
  • Located in the main hall
Luggage Carts
Luggage Carts
  • Free
Station Plan
  • Hall 1: main entrance, platform 1-4 for trains to Germany, Austria, and regional destinations
  • Hall 2: ticket office and waiting area
Public transit options for Praha-Holesovice
  • Metro: Line C
  • Tram: Lines 6, 12, 17
  • Bus: Several lines available
Praha Masarykovo NádražíWifiLockersParkingDiningATMTaxisAccessibilityWCHotelLost and Found OfficeTicket OfficeBike ParkingBike RentalCar RentalInformation DeskLuggage Carts
Amenities at train station
WifiWifi
LockersLockers
ParkingParking
DiningDining
ATMATM
TaxisTaxis
AccessibilityAccessibility
WCWC
HotelHotel
Lost and Found OfficeLost and Found Office
Ticket OfficeTicket Office
Bike ParkingBike Parking
Bike RentalBike Rental
Car RentalCar Rental
Information DeskInformation Desk
Luggage CartsLuggage Carts
information
phone
Phone Number
ticketOfficeHours
Ticket Office Hours
  • 6:00 AM - 10:00 PM Monday - Sunday
platformCount
Number of platforms
5
Wifi
Wifi
  • Free
Parking
Parking
  • Parking is available nearby with several public parking options.
Dining
Dining
  • Restaurant Kotleta
  • Café Imperial
Taxis
Taxis
  • Outside the main entrance.
Accessibility
Accessibility
  • Ramps.
WC
WC
  • CZK 10
Hotel
Hotel
  • Hotel Kings Court
  • Grand Hotel Bohemia
  • Hotel Paris Prague
Lost and Found Office
Lost and Found Office
  • Located in the main hall
Car Rental
Car Rental
  • Avis
  • Europcar
Information Desk
Information Desk
  • Located in the main hall
Luggage Carts
Luggage Carts
  • Free
Station Plan
  • Hall 1: main entrance, platform 1-5 for regional and suburban trains
Public transit options for Praha Masarykovo Nádraží
  • Metro: Line B
  • Tram: Lines 3, 5, 14, 24
  • Bus: Several lines available
Praha-VršoviceWifiLockersParkingDiningTaxisAccessibilityWCHotelLost and Found OfficeTicket OfficeBike ParkingInformation DeskLuggage Carts
Amenities at train station
WifiWifi
LockersLockers
ParkingParking
DiningDining
TaxisTaxis
AccessibilityAccessibility
WCWC
HotelHotel
Lost and Found OfficeLost and Found Office
Ticket OfficeTicket Office
Bike ParkingBike Parking
Information DeskInformation Desk
Luggage CartsLuggage Carts
information
phone
Phone Number
ticketOfficeHours
Ticket Office Hours
  • 6:00 AM - 10:00 PM Monday - Sunday
ticketOfficeHours
Distance to city center
3 km
platformCount
Number of platforms
4
Wifi
Wifi
  • Free
Parking
Parking
  • Parking is available near the station, with access from Boženy Němcové street.
Dining
Dining
  • Ansámbl
  • Bad Flash Bar
  • Café Sladkovský
Taxis
Taxis
  • Outside the main entrance.
Accessibility
Accessibility
  • Ramps, restrooms.
WC
WC
  • CZK 10
Hotel
Hotel
  • Hotel Mars
  • Hotel Slavia
  • Hotel Nabucco
Lost and Found Office
Lost and Found Office
  • Located in the main hall
Information Desk
Information Desk
  • Located in the main hall
Luggage Carts
Luggage Carts
  • Free
Station Plan
  • Hall 1: main entrance, platforms 1-4 for regional and suburban trains
Public transit options for Praha-Vršovice
  • Tram: Line 6, Line 7, Line 24
  • Bus: Several lines available
  • Train: Connections to Praha hlavní nádraží
Praha-Ruzyně nádražíParkingDiningATMWCHotelBike Parking
Amenities at train station
ParkingParking
DiningDining
ATMATM
WCWC
HotelHotel
Bike ParkingBike Parking
information
ticketOfficeHours
Distance to city center
7 km
Prague - KačerovWifiParkingDiningTaxisAccessibilityWCHotelTicket OfficeBike ParkingInformation DeskLuggage Carts
Amenities at train station
WifiWifi
ParkingParking
DiningDining
TaxisTaxis
AccessibilityAccessibility
WCWC
HotelHotel
Ticket OfficeTicket Office
Bike ParkingBike Parking
Information DeskInformation Desk
Luggage CartsLuggage Carts
information
phone
Phone Number
ticketOfficeHours
Ticket Office Hours
  • 5:00 AM - 12:00 AM Monday - Sunday
ticketOfficeHours
Distance to city center
5 km
platformCount
Number of platforms
2
Wifi
Wifi
  • Free
Parking
Parking
  • Parking is available near the station, with access from the main road.
Dining
Dining
  • Restaurant U Kačerova
  • Pizza Coloseum Budějovická
Taxis
Taxis
  • Outside the main entrance.
Accessibility
Accessibility
  • Elevators, ramps.
WC
WC
  • CZK 10
Hotel
Hotel
  • Hotel ILF
  • Hotel Oya
  • Hotel Pankrác
Information Desk
Information Desk
  • Located in the main hall
Luggage Carts
Luggage Carts
  • Free
Station Plan
  • Hall 1: main entrance, platform access for Metro Line C
  • Hall 2: bus connections
Public transit options for Prague - Kačerov
  • Metro: Line C
  • Bus: Several lines available
Praha-SmichovParkingDiningATMAccessibilityWCHotelBike ParkingBike Rental
Amenities at train station
ParkingParking
DiningDining
ATMATM
AccessibilityAccessibility
WCWC
HotelHotel
Bike ParkingBike Parking
Bike RentalBike Rental
information
ticketOfficeHours
Distance to city center
3 km
Amenities at train station
WifiWifi
LockersLockers
ParkingParking
DiningDining
ATMATM
TaxisTaxis
AccessibilityAccessibility
WCWC
HotelHotel
ShowerShower
LoungeLounge
Lost and Found OfficeLost and Found Office
Ticket OfficeTicket Office
Bike ParkingBike Parking
Bike RentalBike Rental
Car RentalCar Rental
Information DeskInformation Desk
Luggage CartsLuggage Carts
information
phone
Phone Number
ticketOfficeHours
Ticket Office Hours
  • 6:00 AM - 10:00 PM Monday - Sunday
ticketOfficeHours
Distance to city center
1 km
platformCount
Number of platforms
7
Wifi
Wifi
  • Free
Parking
Parking
  • The car park is open 7 days a week, 24 hours a day. Access via Wilsonova Street.
Dining
Dining
  • Restaurant Fantova Kavárna
  • Sushi Time
Taxis
Taxis
  • Outside the main entrance.
Accessibility
Accessibility
  • Elevators, ramps.
WC
WC
  • CZK 10
Hotel
Hotel
  • Hotel Esplanade Prague
  • Falkensteiner Hotel Maria Prag
  • Hotel City Central
Shower
Shower
  • Cost CZK 100
Lounge
Lounge
  • Located in the main hall
Lost and Found Office
Lost and Found Office
  • Located in the main hall
Car Rental
Car Rental
  • Avis
  • Europcar
  • Hertz
Information Desk
Information Desk
  • Located in the main hall
Luggage Carts
Luggage Carts
  • Free
Station Plan
  • Hall 1: main entrance, platform 1-7 for trains to Germany, Austria, Slovakia, and regional destinations
  • Hall 2: Metro connections
Public transit options for Praha hlavní nádraží
  • Metro: Line C
  • Tram: Lines 5, 9, 26
  • Bus: Several lines available
HomeTrainsTrain Times to BrusselsPrague to Brussels train

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