Travel Information
Compare train, bus, and flight for Prague to Brussels
Omio recommends booking the flight as it is the most popular option from Prague to Brussels among Omio's users. If you are prioritising price take the bus with prices starting from €44. For those with little time consider booking a flight which can get you there in 3h 28m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.2 - 0.6kg. The ticket price range depends on the travel mode: a bus costs an average of €44, and a flight costs an average of €21.
Distance: 717 km
Compare flight with
Most popular Flight | Train | Bus |
|---|---|---|
€128 Average price | €84 Average price | €69 Average price Cheapest |
6h 28m Average total duration Fastest 3h 28m Onboard + 3h 0m Additional time* | 12h 16m Average total duration 11h 46m Onboard + 30m Additional time* | 15h 26m Average total duration 14h 56m Onboard + 30m Additional time* |
2.2 - 4.3kg CO2 emissions | 0.2 - 0.6kg CO2 emissions Lowest | 0.7 - 1.8kg CO2 emissions |
![]() Most popular airline | ![]() Most popular train company | ![]() Most popular bus company |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Travel optionsfrom Prague to Brussels
How to get from Prague to Brussels by train, bus or flight.
Our recommendation
The best way to travel from Prague to Brussels is by taking a train because it’s the best combination of price and speed.
RJ 478 · ICE 956 · ICE 1612:33 AM13h02Prague hlavní nádraží1:35 PMBrussels-Midi€801One-way2 transfers
Cheapest
RJ 478 · ICE 956 · ICE 1612:33 AM13h02Prague hlavní nádraží1:35 PMBrussels-Midi€801One-way2 transfers
Fastest
SN281011:50 AM1h30Prague Vaclav Havel Airport1:20 PMBrussels Airport€3251One-way0 transfers
Other options
rj 382 · IC 2442 · ICE 2591 · ICE 1010:31 AM11h04Prague hlavní nádraží9:35 PMBrussels-Midi€951One-way3 transfers
rj 178 · IC 2440 · ICE 2589 · ICE 128:31 AM11h04Prague hlavní nádraží7:35 PMBrussels-Midi€951One-way3 transfers
rj 384 · IC 2048 · ICE 2587 · ICE 146:31 AM11h04Prague hlavní nádraží5:35 PMBrussels-Midi€951One-way3 transfers
FlixBus · FlixBus10:35 AM15h10Praha, ÚAN Florenc1:45 AMBrussels, Brussels South (Gare du Midi)€831One-way1 transfer
FlixBus · FlixBus · FlixBus9:10 AM16h35Praha, Na Knížecí1:45 AMBrussels, Brussels South (Gare du Midi)€831One-way2 transfers
FlixBus4:15 PM15h05Praha, ÚAN Florenc7:20 AMBrussels, Brussels South (Gare du Midi)€901One-way0 transfers
SK1768 · SK158910:40 AM7h35Prague Vaclav Havel Airport6:15 PMBrussels Airport€2431One-way1 transfer
SK2736 · SK5973:20 PM4h30Prague Vaclav Havel Airport7:50 PMBrussels Airport€2571One-way1 transfer
U27930+
93984:20 PM6h46Prague Vaclav Havel Airport11:06 PMBrussels-Midi€2621One-way1 transfer
Find all the dates and times for this journey by train, bus, flight, and ferry .
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FAQs: Travel from Prague to Brussels
Travel to Brussels easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Prague to Brussels.

This is compared to other travel options from Prague to Brussels:
A bus is €15 less than a train for this route with tickets for a train from Prague to Brussels costing on average €84.
A bus is €58 less than a flight for this route with tickets for a flight from Prague to Brussels costing on average €128.
Other travel options to Brussels take longer:
Train takes on average 11h 46m.
Bus takes on average 14h 56m.
- Around 41 flights per day.
- Around 14 buses per day.
- Around 8 trains per day.
However, we recommend checking specific travel dates for your route between Prague and Brussels as scheduled services by train, bus, and flight can vary by season or day of the week.
- Flights mostly depart from Prague Vaclav Havel Airport and arrive in Brussels Airport.
- Trains mostly depart from Prague hlavní nádraží and arrive in Brussels-Midi.
- Buses mostly depart from Praha, ÚAN Florenc and arrive in Brussels, Brussels South (Gare du Midi).
- Travel with České dráhy, Deutsche Bahn, Alibus, ÖBB | Euro City (EC), České dráhy (ČD), ÖBB | Railjet to go to Brussels by train.
- Travel with FlixBus, BlaBlaCar Bus to go to Brussels by bus.
- Travel with Ryanair, Buzz, Brussels Airlines, Smartwings, KLM, Lot Polish Airlines, KLM Cityhopper, Sas Airways, Lufthansa, Helvetic Airways, Swiss, Air Baltic, Lufthansa Cityline, TAP Portugal to go to Brussels by flight.
- 0 direct trains per day with Alibus.
- 2 direct buses per day with FlixBus.
- 4 direct flights per day with Ryanair, Buzz, Brussels Airlines, Smartwings.
Travelling from Prague to Brussels: related information
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