Prague to Brussels bus with FlixBus

Thu, Nov 20
+ Add return
FlixBus
BlaBlaCar Bus
AirCoach
Navette Beauvais
Alsa
1,000+ travel companies
FlixBus
BlaBlaCar Bus
AirCoach
Navette Beauvais
Alsa
1,000+ travel companies
QR-Code
Scan to get our free app
Use our app to get live travel updates and book mobile tickets for trains, buses, flights, and ferries.
App Store
rate4.9
42K ratings
Google Play
rate4.6
136K reviews

The cheapest and fastest buses from Prague to Brussels

Showing times and prices for Nov 21

Cheapest price

€45

Average price

€72

Fastest journey

12 h

Average duration

15 h 32 m

Buses per day

14

Distance

717 km

Cheap tickets

The best way to find a cheap bus ticket from Prague to Brussels is to book your journey as far in advance as possible and to avoid traveling at rush hour.

The average ticket from Prague to Brussels will cost around €72 if you buy it on the day, but the cheapest tickets can be found for only €45.

Fast buses

Of the 14 buses that leave Prague for Brussels on Fri, Nov 21, 2 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.

On Fri, Nov 21 the direct buses cover the 717 km distance in an average of 15 h 32 m but if you time it right, some buses will get you there in just 12 h .

On Fri, Nov 21 the slowest buses will take 17 h 10 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.

Regiojet(Prague -> London)
06:00PM12h00
Praha, ÚAN Florenc
06:00AMBrussels, Brussels South (Gare du Midi)
451One-way
0 transfers
FlixBusFlixBus · FlixBus
08:40PM18h55
Praha, Na Knížecí
03:35PMBrussels, Brussels South (Gare du Midi)
581One-way
1 transfer
FlixBusFlixBus · FlixBus
08:15PM19h20
Praha, ÚAN Florenc
03:35PMBrussels, Brussels South (Gare du Midi)
581One-way
1 transfer
FlixBusFlixBus · FlixBus · FlixBus
04:45PM19h40
Prague, Central Train Station
12:25PMBrussels, Avenue des Magnolias (King Baudouin)
611One-way
2 transfers
FlixBusFlixBus · FlixBus
04:15PM17h45
Praha, ÚAN Florenc
10:00AMBrussels, Gare Du Midi
641One-way
1 transfer

Travel Information

Compare train, bus, and flight for Prague to Brussels

Omio recommends booking the flight as it is the most popular option from Prague to Brussels among Omio's users. If you are prioritising price take the bus with prices starting from €27. For those with little time consider booking a flight which can get you there in 2h 27m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.2 - 0.6kg. The ticket price range depends on the travel mode: a bus costs an average of €27, and a flight costs an average of €34.

Distance: 717 km

Compare bus with

Bus
Most popular
Flight
Train

€66

Average price

Cheapest

€192

Average price

€161

Average price

14h 9m

Average total duration

13h 39m

Onboard

+

30m

Additional time*

5h 27m

Average total duration

Fastest

2h 27m

Onboard

+

3h 0m

Additional time*

13h 42m

Average total duration

13h 12m

Onboard

+

30m

Additional time*

0.7 - 1.8kg

CO2 emissions

2.2 - 4.3kg

CO2 emissions

0.2 - 0.6kg

CO2 emissions

Lowest
FlixBus

Most popular bus company

Ryanair

Most popular airline

Deutsche Bahn

Most popular train company

Direct Options

Direct Options

Direct Options

Additional time: Average total travel duration to departure point, security checks and transfers.

Live departures

Prague to Brussels bus times

The table below shows live departures for Prague to Brussels buses for today, Thursday, November 20. You can also manually refresh the results below to see updated bus journeys.

Last updated at 12:08 AM
ProviderDepartsDurationArrivesTransfers
Tickets
meinfernbus_flixbusFlixBus · FlixBus · FlixBus4:50 AM Prague, Central Train Station
19h50
12:40 AM Brussels, Brussels South (Gare du Midi)2 transfers
meinfernbus_flixbusFlixBus · FlixBus7:30 AM Praha, ÚAN Florenc
17h10
12:40 AM Brussels, Brussels South (Gare du Midi)1 transfer
meinfernbus_flixbusFlixBus · FlixBus · FlixBus8:55 AM Praha, Zličín
17h40
2:35 AM Brussels, Brussels South (Gare du Midi)2 transfers
meinfernbus_flixbusFlixBus · FlixBus9:30 AM Praha, ÚAN Florenc
17h05
2:35 AM Brussels, Brussels South (Gare du Midi)1 transfer
meinfernbus_flixbusFlixBus · FlixBus9:55 AM Praha, Na Knížecí
16h40
2:35 AM Brussels, Brussels South (Gare du Midi)1 transfer
meinfernbus_flixbusFlixBus · FlixBus11:50 AM Praha, M. Horákové (Hradčanská)
18h30
6:20 AM Brussels, Brussels South (Gare du Midi)1 transfer
meinfernbus_flixbusFlixBus3:15 PM Praha, ÚAN Florenc
15h05
6:20 AM Brussels, Brussels South (Gare du Midi)0 transfersDirect
meinfernbus_flixbusFlixBus · FlixBus · FlixBus3:45 PM Prague, Central Train Station
19h40
11:25 AM Brussels, Avenue des Magnolias (King Baudouin)2 transfers
meinfernbus_flixbusFlixBus · FlixBus4:45 PM Praha, Na Knížecí
19h00
11:45 AM Brussels, Brussels South (Gare du Midi)1 transfer
meinfernbus_flixbusFlixBus · FlixBus5:00 PM Praha, ÚAN Florenc
18h25
11:25 AM Brussels, Avenue des Magnolias (King Baudouin)1 transfer
blablacarbus30513 · 14666:00 PM Praha, ÚAN Florenc
18h30
12:30 PM Brussels, Brussels South (Gare du Midi)1 transfer
meinfernbus_flixbusFlixBus · FlixBus7:15 PM Praha, ÚAN Florenc
19h20
2:35 PM Brussels, Brussels South (Gare du Midi)1 transfer
meinfernbus_flixbusFlixBus · FlixBus7:40 PM Praha, Na Knížecí
18h55
2:35 PM Brussels, Brussels South (Gare du Midi)1 transfer

This is the last bus of the day.

Find all the dates and times for this journey

Compare prices and tickets Prague to Brussels by train, bus, or flight

Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.

Thu
Nov 20
Fri
Nov 21
Sat
Nov 22
Sun
Nov 23
Mon
Nov 24
Tue
Nov 25
Wed
Nov 26
Thu
Nov 27
Fri
Nov 28
Sat
Nov 29
Sun
Nov 30
Mon
Dec 01
Tue
Dec 02
Wed
Dec 03
Thu
Dec 04
Fri
Dec 05
Sat
Dec 06
Sun
Dec 07
Mon
Dec 08
Tue
Dec 09
Wed
Dec 10

Journey information

Overview: Bus from Prague to Brussels

CzechiaCzechia
BelgiumBelgium
Icon of bus

Buses from Prague to Brussels run on average 25 times per day, taking around 13h 39m. Cheap bus tickets for this journey start at €27 if you book in advance.

There are 3 buses per day. The earliest bus runs at 00:10, the last at 23:50. The fastest bus covers the 717 km distance in 12h 0m.

Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Distance
717 km
Average bus duration
13h 39m
Cheapest ticket price
€27
Buses per day
25
Direct buses
3
Fastest bus
12h 0m
First bus
00:10
Last bus
23:50
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information

Bus providers: FlixBus, BlaBlaCar Bus from Prague to BrusselsYou can travel by bus between Prague to Brussels with FlixBus, BlaBlaCar Bus for as low as €27. When you search for schedules and tickets, Omio will show you the best journey

FlixBus

About
FlixBus is one of Europe’s leading low-cost bus companies, founded in Germany and now offering long-distance services across Europe and the United States. In addition to its extensive daytime network, FlixBus also operates overnight buses on select European routes. Standard amenities include free Wi-Fi, power outlets to charge devices, extra legroom, luggage space, and onboard toilets, with snacks and drinks available for purchase. FlixBus offers a single Standard ticket type for all routes, which includes one carry-on bag and one checked bag per passenger. Additional fees apply for extra luggage and for reserving specific seats, such as Extra Seats, Table Seats, or Panorama Seats. This combination of affordability, comfort, and wide coverage makes FlixBus a popular choice for budget-conscious travelers.
Luggage & cancellation policy
Average Duration
14h 50m
Cheapest Price
€25
FlixBus frequency
29 a day
Luggage included
One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Additional luggage
Additional luggage can be purchased for a fee.
Cancellation Policy
You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority boarding; Wheelchair-accessible buses.
Bikes
Bikes are allowed for a fee; must be booked.
Pets
Small pets in carriers allowed; guide dogs travel for free.

BlaBlaCar Bus

About
BlaBlaCar Bus (formerly known as Ouibus or iDBUS) is a long-distance coach company operating in 10 European countries and connecting over 300 destinations. A subsidiary of the French carpooling company BlaBlaCar, it offers comfortable travel with standard amenities such as air conditioning, toilets, USB and power outlets for charging devices, extra legroom, and adjustable seats. Free Wi-Fi is available on select routes. BlaBlaCar Bus offers only a Standard ticket type, which allows passengers to bring one carry-on bag and up to two checked bags per person.
Luggage & cancellation policy
Average Duration
15h 35m
Cheapest Price
€64
BlaBlaCar Bus frequency
1 a day
Luggage included
One carry-on bag up to 7kg and one checked bag up to 20kg.
Additional luggage
Additional luggage can be purchased for a fee.
Cancellation Policy
You can cancel your ticket up to 30 minutes before departure for a refund in the form of a voucher.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority boarding; Accessible seating options.
Bikes
Bikes are allowed; additional fees may apply.

FAQs: Bus from Prague to Brussels

Find answers to the most common questions about traveling from Prague to Brussels by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Brussels, this guide helps you travel smarter and with confidence.

FAQs
Cheap coach tickets from Prague to Brussels can start from as little as €40 when you book in advance. The average coach ticket price for Prague to Brussels is €66; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The coach time from Prague to Brussels is on average 12 h   for the 717 km long journey, but the time it takes to go from Prague to Brussels by coach can vary depending on specific dates or if traveling on weekends and holidays.
The first coach from Prague to Brussels leaves at 02: 50. Plan your trip with the Journey Planner   from Omio.
The last coach from Prague to Brussels leaves at 22: 50.
Yes, there are 4 direct coaches a day from Prague to Brussels with FlixBus. Schedules can vary on holidays or weekends with fewer direct coaches.
For the best Prague to Brussels coach to buy, you can travel safely and comfortably with FlixBus or BlaBlaCar Bus. However, it's always good to check all possible coach companies with services between Prague and Brussels to compare what amenities they may offer.

Passengers board the coach most frequently from Prague, Central Train Station, which is located around 1.8 miles (2.9 km) away from the city centre, and they get off the coach at Bruxelles, Gare du Nord, located 1.1 miles (1.7 km) away from the city centre.

The cheapest month to travel from Prague to Brussels by coach is December.
You have options as you can travel from Prague to Brussels 3 different ways: train, coach or flight.
No, the coach from Prague to Brussels has no accessibility options.
No, there are no bathrooms on board the coach from Prague to Brussels.
No, bikes are not allowed on board the coach from Prague to Brussels.

To find the cheapest bus tickets for your trip from Prague to Brussels, follow these tips:

  • Book in advance: Tickets are often cheaper when booked early.
  • Be flexible with dates and times: Traveling during off-peak hours or on weekdays can help you save money.
  • Use our search filters: Sort results by price to quickly identify the most affordable options.
  • Look for special deals or discounts: Check for promotions or discounts available on our website and app.
  • Start your search now and compare ticket prices to find the best deal!

    Yes, there is food available to purchase on board the coach from Prague to Brussels.
    No, luggage for the coach from Prague to Brussels needs to be booked in addition.
    No, there are no additional luggage options for the coach from Prague to Brussels.
    Unfortunately, pets are not allowed on the coach from Prague to Brussels.
    No, there are no USB plugs on board the coach from Prague to Brussels.
    No, there is no WiFi on board the coach from Prague to Brussels.

    popular bus stations

    Popular bus stations from Prague to Brussels

    Prague
    Brussels
    The major bus station for departures in Prague is Praha, Na Knížecí. Find all the information you need to know about services, amenities and connections at Praha, Na Knížecí for your trip from Prague to Brussels.
    Amenities at bus station
    WifiWifi
    ParkingParking
    DiningDining
    ATMATM
    TaxisTaxis
    AccessibilityAccessibility
    WCWC
    information
    ticketOfficeHours
    Distance to city center
    2 km
    carConnection
    Car connection
    Ostrovského
    Wifi
    Wifi
    • Free Wi-Fi
    Dining
    Dining
    • Café Na Knížecí (in the station)
    • Bistro Praha (0.2 km)
    • Restaurace U Knížete (0.5 km).
    Taxis
    Taxis
    • Available outside the main entrance.
    Accessibility
    Accessibility
    • Elevators, ramps
    WC
    WC
    • Available in the station.
    Public transit options for Praha, Na Knížecí
    • Bus: 137, 176, 191 Metro: B
    Amenities at bus station
    WifiWifi
    ParkingParking
    DiningDining
    ATMATM
    TaxisTaxis
    AccessibilityAccessibility
    WCWC
    Ticket OfficeTicket Office
    information
    ticketOfficeHours
    Ticket Office Hours
    • 00:00-23:59
    ticketOfficeHours
    Distance to city center
    1 km
    carConnection
    Car connection
    Wilsonova
    Wifi
    Wifi
    • Free Wi-Fi
    Dining
    Dining
    • Czech Bistro (in the station)
    • Fast Food Express (in the station)
    • Bohemian Café (0.2 km).
    Taxis
    Taxis
    • Available outside the main entrance.
    Accessibility
    Accessibility
    • Elevators, ramps
    WC
    WC
    • Available in the station.
    Public transit options for Praha, Hlavní Nádraží
    • Bus: 135, 175, 207 Metro: C Train: All major s
    Amenities at bus station
    WifiWifi
    ParkingParking
    DiningDining
    ATMATM
    TaxisTaxis
    AccessibilityAccessibility
    WCWC
    Ticket OfficeTicket Office
    information
    ticketOfficeHours
    Ticket Office Hours
    • 06:00-23:00
    ticketOfficeHours
    Distance to city center
    1 km
    carConnection
    Car connection
    Křižíkova
    Wifi
    Wifi
    • Free Wi-Fi
    Dining
    Dining
    • Cafeteria Florenc (in the station)
    • Bistro Florenc (0.2 km)
    • Restaurace U Rozvařilů (0.5 km).
    Taxis
    Taxis
    • Available outside the main entrance.
    Accessibility
    Accessibility
    • Elevators, ramps
    WC
    WC
    • Available in the station.
    Public transit options for Praha, ÚAN Florenc
    • Bus: 133, 135, 175, 207 Metro: B, C
    Praha, Nádraží Holešovice
    Amenities at bus station
    WifiWifi
    ParkingParking
    DiningDining
    ATMATM
    TaxisTaxis
    AccessibilityAccessibility
    WCWC
    Ticket OfficeTicket Office
    information
    ticketOfficeHours
    Ticket Office Hours
    • 00:00-23:59
    ticketOfficeHours
    Distance to city center
    11 km
    carConnection
    Car connection
    Bryanská
    Wifi
    Wifi
    • Free Wi-Fi
    Dining
    Dining
    • Cafeteria Černý Most (in the station)
    • Czech Bistro (in the station)
    • Fast Food Express (in the station).
    Taxis
    Taxis
    • Available outside the main entrance.
    Accessibility
    Accessibility
    • Elevators, ramps
    WC
    WC
    • Available in the station.
    Public transit options for Praha, Černý Most
    • Bus: 177, 195, 201 Metro: B
    Praha, M. Horákové (Hradčanská)Taxis
    Amenities at bus station
    TaxisTaxis
    information
    ticketOfficeHours
    Distance to city center
    1 km
    carConnection
    Car connection
    Milady Horákové
    Public transit options for Praha, M. Horákové (Hradčanská)
    • Bus: 131, 174, 180 Metro: A Train: S4, S5
    Praha, Zličín
    information
    Praha, Letiště Václava Havla
    information
    Praha, Roztyly
    information

    The Omio App Makes Travel Planning Easy

    We’ll get you where you want to go. From live train updates to mobile tickets, our innovative app is the ideal way to plan and keep track of your travel.

    ios-badge
    android-badge
    Hand With Phone