1,000+ travel companies
1,000+ travel companies
Scan to get our free app
Use our app to get live travel updates and book mobile tickets for trains, buses, flights, and ferries.
App Store
4.942K ratings
Google Play
4.6136K reviews
The cheapest and fastest buses from Prague to Brussels
Showing times and prices for Feb 20
Cheapest price
€77
Average price
€102
Fastest journey
14 h 50 m
Average duration
15 h 53 m
Buses per day
12
Distance
717 km
Cheap tickets
The best way to find a cheap bus ticket from Prague to Brussels is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Prague to Brussels will cost around €102 if you buy it on the day, but the cheapest tickets can be found for only €77.
Fast buses
Of the 12 buses that leave Prague for Brussels on Fri, Feb 20, 2 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Fri, Feb 20 the direct buses cover the 717 km distance in an average of 15 h 53 m but if you time it right, some buses will get you there in just 14 h 50 m .
On Fri, Feb 20 the slowest buses will take 16 h 55 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
FlixBus11:05PM14h50
Praha, ÚAN Florenc01:55PMBrussels, Brussels South (Gare du Midi)
€771One-way
0 transfers
FlixBus04:15PM15h05
Praha, ÚAN Florenc07:20AMBrussels, Brussels South (Gare du Midi)
€841One-way
0 transfers
FlixBus · FlixBus04:15PM17h45
Praha, ÚAN Florenc10:00AMBrussels, Gare Du Midi
€1001One-way
1 transfer
FlixBus · FlixBus06:00PM18h25
Praha, ÚAN Florenc12:25PMBrussels, Avenue des Magnolias (King Baudouin)
€1011One-way
1 transfer
FlixBus · FlixBus · FlixBus06:45PM19h10
Prague, Central Train Station01:55PMBrussels, Brussels South (Gare du Midi)
€1021One-way
2 transfers
FlixBus11:05PM14h50
Praha, ÚAN Florenc01:55PMBrussels, Brussels South (Gare du Midi)
€771One-way
0 transfers
FlixBus04:15PM15h05
Praha, ÚAN Florenc07:20AMBrussels, Brussels South (Gare du Midi)
€841One-way
0 transfers
FlixBus · FlixBus09:50PM16h05
Praha, Na Knížecí01:55PMBrussels, Brussels South (Gare du Midi)
€1021One-way
1 transfer
FlixBus · FlixBus10:55AM16h30
Praha, Na Knížecí03:25AMBrussels, Brussels South (Gare du Midi)
€1021One-way
1 transfer
FlixBus · FlixBus10:30AM16h55
Praha, ÚAN Florenc03:25AMBrussels, Brussels South (Gare du Midi)
€1021One-way
1 transfer
Travel Information
Compare train, bus, and flight for Prague to Brussels
Omio recommends booking the flight as it is the most popular option from Prague to Brussels among Omio's users. If you are prioritising price take the bus with prices starting from €40. For those with little time consider booking a flight which can get you there in 3h 21m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.2 - 0.6kg. The ticket price range depends on the travel mode: a bus costs an average of €40, and a train costs an average of €13.
Distance: 717 km
Compare bus with
| Bus | Most popular Flight | Train |
|---|---|---|
€66 Average price Cheapest | €100 Average price | €101 Average price |
15h 10m Average total duration 14h 40m Onboard + 30m Additional time* | 6h 21m Average total duration Fastest 3h 21m Onboard + 3h 0m Additional time* | 12h 11m Average total duration 11h 41m Onboard + 30m Additional time* |
0.7 - 1.8kg CO2 emissions | 2.2 - 4.3kg CO2 emissions | 0.2 - 0.6kg CO2 emissions Lowest |
Most popular bus company |  Most popular airline |  Most popular train company |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Live departures
Prague to Brussels bus times
The table below shows live departures for Prague to Brussels buses for tomorrow, Friday, February 20. You can also manually refresh the results below to see updated bus journeys.
Last updated at 10:07 PM
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
| FlixBus · FlixBus | 7:40 AM Praha, ÚAN Florenc | 17h05 | 12:45 AM Brussels, Brussels South (Gare du Midi) | 1 transfer | |
| FlixBus · FlixBus · FlixBus | 8:55 AM Praha, Zličín | 17h30 | 2:25 AM Brussels, Brussels South (Gare du Midi) | 2 transfers | |
| FlixBus · FlixBus | 9:30 AM Praha, ÚAN Florenc | 16h55 | 2:25 AM Brussels, Brussels South (Gare du Midi) | 1 transfer | |
| FlixBus · FlixBus | 9:55 AM Praha, Na Knížecí | 16h30 | 2:25 AM Brussels, Brussels South (Gare du Midi) | 1 transfer | |
| FlixBus · FlixBus | 11:50 AM Praha, M. Horákové (Hradčanská) | 18h30 | 6:20 AM Brussels, Brussels South (Gare du Midi) | 1 transfer | |
| FlixBus | 3:15 PM Praha, ÚAN Florenc | 15h05 | 6:20 AM Brussels, Brussels South (Gare du Midi) | 0 transfersDirect | |
| FlixBus · FlixBus | 3:15 PM Praha, ÚAN Florenc | 17h45 | 9:00 AM Brussels, Gare Du Midi | 1 transfer | |
| FlixBus · FlixBus | 4:45 PM Praha, Na Knížecí | 19h00 | 11:45 AM Brussels, Brussels South (Gare du Midi) | 1 transfer | |
| FlixBus · FlixBus | 5:00 PM Praha, ÚAN Florenc | 18h25 | 11:25 AM Brussels, Avenue des Magnolias (King Baudouin) | 1 transfer | |
| FlixBus · FlixBus · FlixBus | 5:45 PM Prague, Central Train Station | 19h10 | 12:55 PM Brussels, Brussels South (Gare du Midi) | 2 transfers | |
| FlixBus · FlixBus | 8:50 PM Praha, Na Knížecí | 16h05 | 12:55 PM Brussels, Brussels South (Gare du Midi) | 1 transfer | |
| FlixBus | 10:05 PM Praha, ÚAN Florenc | 14h50 | 12:55 PM Brussels, Brussels South (Gare du Midi) | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Prague to Brussels by train, bus, or flight
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Fri
Feb 20
Feb 20
Sat
Feb 21
Feb 21
Sun
Feb 22
Feb 22
Mon
Feb 23
Feb 23
Tue
Feb 24
Feb 24
Wed
Feb 25
Feb 25
Thu
Feb 26
Feb 26
Fri
Feb 27
Feb 27
Sat
Feb 28
Feb 28
Sun
Mar 01
Mar 01
Mon
Mar 02
Mar 02
Tue
Mar 03
Mar 03
Wed
Mar 04
Mar 04
Thu
Mar 05
Mar 05
Fri
Mar 06
Mar 06
Sat
Mar 07
Mar 07
Sun
Mar 08
Mar 08
Mon
Mar 09
Mar 09
Tue
Mar 10
Mar 10
Wed
Mar 11
Mar 11
Thu
Mar 12
Mar 12
Why should you book Prague to Brussels buses with Omio?
FlixBus as well as BlaBlaCar Bus or České dráhy offer buses services from Prague to Brussels.
Omio is an official ticket reseller for all your travel options from Prague to Brussels.
Why book with Omio vs FlixBus?
- Compare with other providers: On Omio, you can not only buy tickets for FlixBus, but also compare tickets for the likes of BlaBlaCar Bus or České dráhy to find the best option for your trip from Prague to Brussels.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare FlixBus with all available travel options, which are train, bus and flight to ensure you get the best deal for traveling from Prague to Brussels.
Why book with Omio over Wanderu, Trainline or Checkmybus?
- Compare with other providers: On Omio, you can also compare tickets for the likes of BlaBlaCar Bus or České dráhy to find the best option for your trip from Prague to Brussels.
- Multiple modes of transport: Omio allows you to compare travel options including train, bus and flight to find the ideal travel option from Prague to Brussels.
Journey information
Overview: Bus from Prague to Brussels
Czechia
Belgium
Buses from Prague to Brussels run on average 18 times per day, taking around 14h 40m. Cheap bus tickets for this journey start at €40 but you can travel from only €13 by train.
There are 2 buses per day. The earliest bus runs at 00:10, the last at 23:50. The fastest bus covers the 717 km distance in 12h 0m.
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Train from €13
Distance 717 km |
Average bus duration 14h 40m |
Cheapest ticket price €40 |
Buses per day 18 |
Direct buses 2 |
Fastest bus 12h 0m |
First bus 00:10 |
Last bus 23:50 |
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Train from €13
Bus providers: FlixBus, BlaBlaCar Bus, České dráhy from Prague to BrusselsYou can travel by bus between Prague to Brussels with FlixBus, BlaBlaCar Bus, České dráhy for as low as €13. When you search for schedules and tickets, Omio will show you the best journey
FlixBus
About
FlixBus is one of Europe’s leading low-cost bus companies, founded in Germany and now offering long-distance services across Europe and the United States. In addition to its extensive daytime network, FlixBus also operates overnight buses on select European routes. Standard amenities include free Wi-Fi, power outlets to charge devices, extra legroom, luggage space, and onboard toilets, with snacks and drinks available for purchase. FlixBus offers a single Standard ticket type for all routes, which includes one carry-on bag and one checked bag per passenger. Additional fees apply for extra luggage and for reserving specific seats, such as Extra Seats, Table Seats, or Panorama Seats. This combination of affordability, comfort, and wide coverage makes FlixBus a popular choice for budget-conscious travelers.
Luggage & cancellation policy
Average Duration
14h 50m
Cheapest Price
€44
FlixBus frequency
18 a day
Luggage included
One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Additional luggage
Additional luggage can be purchased for a fee.
Cancellation Policy
You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority boarding; Wheelchair-accessible buses.
Bikes
Bikes are allowed for a fee; must be booked.
Pets
Small pets in carriers allowed; guide dogs travel for free.
BlaBlaCar Bus
About
BlaBlaCar Bus (formerly known as Ouibus or iDBUS) is a long-distance coach company operating in 10 European countries and connecting over 300 destinations. A subsidiary of the French carpooling company BlaBlaCar, it offers comfortable travel with standard amenities such as air conditioning, toilets, USB and power outlets for charging devices, extra legroom, and adjustable seats. Free Wi-Fi is available on select routes. BlaBlaCar Bus offers only a Standard ticket type, which allows passengers to bring one carry-on bag and up to two checked bags per person.
Luggage & cancellation policy
Average Duration
18h 30m
Cheapest Price
€59
BlaBlaCar Bus frequency
1 a day
Luggage included
One carry-on bag up to 7kg and one checked bag up to 20kg.
Additional luggage
Additional luggage can be purchased for a fee.
Cancellation Policy
You can cancel your ticket up to 30 minutes before departure for a refund in the form of a voucher.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority boarding; Accessible seating options.
Bikes
Bikes are allowed; additional fees may apply.
České dráhy
About
Czech Railways (České dráhy, ČD) is the largest railway company in the Czech Republic, connecting major cities, small towns, and even international destinations across Europe. Its extensive fleet of modern trains ranges from comfortable regional services with A/C and onboard WiFi to high-speed trains offering dining cars, power outlets, and premium seating for long-distance journeys. Czech Railways combines affordability and convenience, making it a popular choice for travelers exploring the Czech Republic and beyond.
Luggage & cancellation policy
Average Duration
10h 55m
Cheapest Price
€13
Luggage included
You can transport briefcases, laptops, rucksacks, trolley bags and suitcases on board at no charge.
Additional luggage
Items of luggage must not be so big or heavy that they cannot be carried by a single person, with a generous maximum size of 90 x 60 x 40 cm and a maximum weight of 50kg.
Luggage storage
Luggage can be stored above or below the seat, on the passenger's lap, or in special luggage racks in certain carriages.
Cancellation Policy
Tickets purchased online can be returned free of charge up to 15 minutes before the train's departure.
Refund
If a train is completely canceled, booking fees are refundable, and compensation may be due directly from the rail operator.
Pregnant on board
Being pregnant on board is allowed.
Unaccompagned minor
Automatic compensation for online ČD domestic tickets applies if the system registers a delay of more than 60 minutes at the destination and the ticket was checked by the conductor.
Amenities on board the bus
Food sold onboard
A hearty breakfast is included in the ticket price for sleeper carriage services.
Seat reservation
Seat reservations are included with tickets and adjacent seats are booked wherever possible.
Accessibility
Czech Railways is continuously expanding its fleet of wheelchair-accessible carriages and offers assistance for passengers with limited mobility.
Bikes
Bicycles can be transported, with folding bikes or scooters allowed as hand luggage, while larger bicycles may incur a charge.
Pets
Small pets are allowed on board, but cannot be transported in 1st class, restaurant, or bistro cars.
FAQs: Bus from Prague to Brussels
Find answers to the most common questions about traveling from Prague to Brussels by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Brussels, this guide helps you travel smarter and with confidence.
Cheap coach tickets from Prague to Brussels can start from as little as €40 when you book in advance. The average coach ticket price for Prague to Brussels is €66; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by coach from Prague to Brussels is 12h 0m to travel the 717 km long trip. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest coach from Prague to Brussels leaves at 12:10 AM. Plan your trip with the Journey Planner from Omio.
The latest coach from Prague to Brussels leaves at 11:50 PM.
Yes, there are 2 direct coaches a day from Prague to Brussels with FlixBus. Schedules can vary on holidays or weekends with fewer direct coaches.
When taking a coach from Prague to Brussels, you can count on FlixBus, BlaBlaCar Bus, České dráhy for the best way to get you to Brussels. You can also check all possible coach companies who offer a service between Prague and Brussels and compare the amenities they offer before buying a coach ticket.
When departing from Prague , you have various coach station options to start your trip from including Praha, ÚAN Florenc, Prague, Central Train Station, Praha, Na Knížecí, Praha, Zličín, Praha, M. Horákové (Hradčanská), Praha, Černý Most, Praha, Roztyly, Praha, Letiště Václava Havla, Praha, Nádraží Holešovice . When arriving in Brussels , you can end your trip in coach stations like Brussels, Brussels South (Gare du Midi), Bruxelles, Gare du Nord, Brussels, Avenue des Magnolias (King Baudouin), Brussels, Gare Du Midi, Brussel-Zuid/Midi, Schaerbeek, Bd Roi Albert II (Bruxelles Gare Du Nord), Schaerbeek, Rue du Progrès (Gare du Nord) .Passengers board the coach most frequently from Praha, ÚAN Florenc, which is located around 1 away from the city centre, and they get off the coach at Brussels, Brussels South (Gare du Midi), located 2 away from the city centre.
A trip to Brussels from Prague is worth doing but not as a day trip with a journey time of 12h 0m each way. Check with Omio app the best way to travel.
The cheapest month for a coach from Prague to Brussels is April.
It's helpful to compare your options as there are 3 ways to travel between Prague and Brussels including taking a train, bus, and flight.
Yes, the following accessibility options are available when taking the coach from Prague to Brussels:
- BlaBlaCar Bus
- Assistance
- Priority boarding
- Accessible seating options.
- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
- České dráhy
- Czech Railways is continuously expanding its fleet of wheelchair-accessible carriages and offers assistance for passengers with limited mobility.
Yes, there are bathrooms on board the coach from Prague to Brussels for coach company FlixBus, BlaBlaCar Bus.
Whether you can cancel your coach ticket from Prague to Brussels depends on the coach companies:
- BlaBlaCar Bus
- You can cancel your ticket up to 30 minutes before departure for a refund in the form of a voucher.
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
- České dráhy
- Tickets purchased online can be returned free of charge up to 15 minutes before the train's departure.
Yes, bikes are allowed on board the coach with coach company FlixBus, BlaBlaCar Bus, České dráhy.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
No, there is no food available to purchase on board the coach from Prague to Brussels.
Yes, the following luggage options are included when booking a coach ticket from Prague to Brussels:
- BlaBlaCar Bus
- One carry-on bag up to 7kg and one checked bag up to 20kg.
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
- České dráhy
- You can transport briefcases, laptops, rucksacks, trolley bags and suitcases on board at no charge.
Yes, the following additional luggage options are available when booking a coach ticket from Prague to Brussels:
- BlaBlaCar Bus
- Additional luggage can be purchased for a fee.
- FlixBus
- Additional luggage can be purchased for a fee.
- České dráhy
- Items of luggage must not be so big or heavy that they cannot be carried by a single person, with a generous maximum size of 90 x 60 x 40 cm and a maximum weight of 50kg.
Yes, you can bring your pet on the coach from Prague to Brussels. The following conditions apply:
- FlixBus
- Small pets in carriers allowed
- guide dogs travel for free.
- České dráhy
- Small pets are allowed on board, but cannot be transported in 1st class, restaurant, or bistro cars.
You can reserve your seat on the coach from Prague to Brussels with the following coach company: FlixBus, BlaBlaCar Bus, České dráhy
Yes, there are USB plugs on board the coach from Prague to Brussels with the following coach company: FlixBus, BlaBlaCar Bus.
Yes, there is Wifi on board the coach from Prague to Brussels with the following coach company: FlixBus, BlaBlaCar Bus.
popular bus stations
Popular bus stations from Prague to Brussels
Prague
Brussels
The major bus station for departures in Prague is Praha, ÚAN Florenc. Find all the information you need to know about services, amenities and connections at Praha, ÚAN Florenc for your trip from Prague to Brussels.
Amenities at bus station
Wifi
Parking
Dining
ATM
Taxis
Accessibility
WC
Ticket Officeinformation
Ticket Office Hours
- 06:00-23:00
Distance to city center
1 km
Car connection
KřižíkovaWifi
- Free Wi-Fi
Dining
- Cafeteria Florenc (in the station)
- Bistro Florenc (0.2 km)
- Restaurace U Rozvařilů (0.5 km).
Taxis
- Available outside the main entrance.
Accessibility
- Elevators, ramps
WC
- Available in the station.
Public transit options for Praha, ÚAN Florenc
- Bus: 133, 135, 175, 207 Metro: B, C
Amenities at bus station
WifiParkingDiningATMTaxisAccessibilityWCTicket Officeinformation
Ticket Office Hours
- 00:00-23:59
Distance to city center
1 kmCar connection
WilsonovaWifi
- Free Wi-Fi
Dining
- Czech Bistro (in the station)
- Fast Food Express (in the station)
- Bohemian Café (0.2 km).
Taxis
- Available outside the main entrance.
Accessibility
- Elevators, ramps
WC
- Available in the station.
Public transit options for Praha, Hlavní Nádraží
- Bus: 135, 175, 207 Metro: C Train: All major s
Amenities at bus station
WifiParkingDiningATMTaxisAccessibilityWCinformation
Distance to city center
2 kmCar connection
OstrovskéhoWifi
- Free Wi-Fi
Dining
- Café Na Knížecí (in the station)
- Bistro Praha (0.2 km)
- Restaurace U Knížete (0.5 km).
Taxis
- Available outside the main entrance.
Accessibility
- Elevators, ramps
WC
- Available in the station.
Public transit options for Praha, Na Knížecí
- Bus: 137, 176, 191 Metro: B
The major bus station for arrivals in Brussels is Brussels, Brussels South (Gare du Midi). Find all the information you need to know about services, amenities and connections at Brussels, Brussels South (Gare du Midi) for your trip to Brussels from Prague.
Amenities at bus station
WifiParkingDiningATMTaxisAccessibilityWCTicket Officeinformation
Ticket Office Hours
- 06:00-23:00
Distance to city center
2 kmCar connection
Avenue FonsnyWifi
- Free Wi-Fi
Dining
- Cafeteria Midi (in the station)
- Belgian Bites (in the station)
- Fritland Express (0.5 km).
Taxis
- Available outside the main entrance.
Accessibility
- Elevators, ramps
WC
- Available in the station.
Public transit options for Brussels, Brussels South (Gare du Midi)
- Bus: 27, 49, 50, 78 Metro: 2, 6 Train: IC, S, Thalys, Eurostar
Amenities at bus station
WifiParkingDiningATMTaxisAccessibilityWCTicket Officeinformation
Ticket Office Hours
- 06:00-23:59
Distance to city center
1 kmCar connection
Rue du ProgrèsWifi
- Free Wi-Fi
Dining
- Cafeteria Noord (in the station)
- Quick Brussels Noord (in the station)
- Le Pain Quotidien (0.5 km).
Taxis
- Available outside the main entrance.
Accessibility
- Elevators, ramps
WC
- Available in the station.
Public transit options for Brussels-Noord
- Bus: 14, 57, 58 Metro: 2, 6 Train: IC, S1, S2
Brussel, Avenue des Magnolias (Koning Boudewijn)
information
Most popular bus connections from Prague
More options for your journey from Prague to Brussels
Here are some other resources that might have the information you need
Most popular buses to and from Brussels and Prague
Most popular bus connections to Brussels
The Omio App Makes Travel Planning Easy
We’ll get you where you want to go. From live train updates to mobile tickets, our innovative app is the ideal way to plan and keep track of your travel.
