The cheapest and fastest buses from Prague to Brussels
Cheapest price
€66
Average price
€82
Fastest journey
14 h 40 m
Average duration
15 h 27 m
Buses per day
14
Distance
717 km
The best way to find a cheap bus ticket from Prague to Brussels is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Prague to Brussels will cost around €82 if you buy it on the day, but the cheapest tickets can be found for only €66.
Of the 14 buses that leave Prague for Brussels on Mon, Jul 06, 2 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Mon, Jul 06 the direct buses cover the 717 km distance in an average of 15 h 27 m but if you time it right, some buses will get you there in just 14 h 40 m .
On Mon, Jul 06 the slowest buses will take 16 h 35 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
FlixBus11:05 PM14h50Praha, ÚAN Florenc1:55 PMBrussels, Brussels South (Gare du Midi)€661One-way0 transfers
FlixBus4:15 PM15h05Praha, ÚAN Florenc7:20 AMBrussels, Brussels South (Gare du Midi)€661One-way0 transfers
FlixBus · FlixBus9:50 PM16h05Praha, Na Knížecí1:55 PMBrussels, Brussels South (Gare du Midi)€781One-way1 transfer
FlixBus · FlixBus · FlixBus6:45 PM19h10Prague, Central Train Station1:55 PMBrussels, Brussels South (Gare du Midi)€781One-way2 transfers
FlixBus · FlixBus2:30 PM16h50Praha, Černý Most7:20 AMBrussels, Brussels South (Gare du Midi)€841One-way1 transfer
FlixBus · FlixBus11:05 AM14h40Praha, ÚAN Florenc1:45 AMBrussels, Brussels South (Gare du Midi)€851One-way1 transfer
FlixBus11:05 PM14h50Praha, ÚAN Florenc1:55 PMBrussels, Brussels South (Gare du Midi)€661One-way0 transfers
FlixBus4:15 PM15h05Praha, ÚAN Florenc7:20 AMBrussels, Brussels South (Gare du Midi)€661One-way0 transfers
FlixBus · FlixBus9:50 PM16h05Praha, Na Knížecí1:55 PMBrussels, Brussels South (Gare du Midi)€781One-way1 transfer
FlixBus · FlixBus · FlixBus9:10 AM16h35Praha, Na Knížecí1:45 AMBrussels, Brussels South (Gare du Midi)€841One-way2 transfers
Travel Information
Compare train, bus, and flight for Prague to Brussels
Omio recommends booking the flight as it is the most popular option from Prague to Brussels among Omio's users. If you are prioritising price take the bus with prices starting from €40. For those with little time consider booking a flight which can get you there in 3h 21m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.2 - 0.6kg. The ticket price range depends on the travel mode: a bus costs an average of €40, and a flight costs an average of €22.
Distance: 717 km
Compare bus with
| Bus | Most popular Flight | Train |
|---|---|---|
€69 Average price Cheapest | €127 Average price | €101 Average price |
15h 24m Average total duration 14h 54m Onboard + 30m Additional time* | 6h 21m Average total duration Fastest 3h 21m Onboard + 3h 0m Additional time* | 12h 20m Average total duration 11h 50m Onboard + 30m Additional time* |
0.7 - 1.8kg CO2 emissions | 2.2 - 4.3kg CO2 emissions | 0.2 - 0.6kg CO2 emissions Lowest |
![]() Most popular bus company | ![]() Most popular airline | ![]() Most popular train company |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Live departures
Prague to Brussels bus times
The table below shows live departures for Prague to Brussels buses for today, Sunday, July 5. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
FlixBus · FlixBus · FlixBus | 6:45 PM Prague, Central Train Station | 19h10 | 1:55 PM Brussels, Brussels South (Gare du Midi) | 2 transfers | |
30513 · 1466 | 7:00 PM Praha, ÚAN Florenc | 18h30 | 1:30 PM Brussels, Brussels South (Gare du Midi) | 1 transfer | |
FlixBus · FlixBus | 9:50 PM Praha, Na Knížecí | 16h05 | 1:55 PM Brussels, Brussels South (Gare du Midi) | 1 transfer | |
FlixBus | 11:05 PM Praha, ÚAN Florenc | 14h50 | 1:55 PM Brussels, Brussels South (Gare du Midi) | 0 transfersDirect | |
| Monday, July 6 | |||||
FlixBus · FlixBus · FlixBus | 9:10 AM Praha, Na Knížecí | 16h35 | 1:45 AM Brussels, Brussels South (Gare du Midi) | 2 transfers | |
FlixBus · FlixBus · FlixBus | 9:55 AM Praha, Zličín | 17h40 | 3:35 AM Brussels, Brussels South (Gare du Midi) | 2 transfers | |
FlixBus · FlixBus | 10:55 AM Praha, Na Knížecí | 16h40 | 3:35 AM Brussels, Brussels South (Gare du Midi) | 1 transfer | |
FlixBus · FlixBus | 11:05 AM Praha, ÚAN Florenc | 14h40 | 1:45 AM Brussels, Brussels South (Gare du Midi) | 1 transfer | |
FlixBus · FlixBus | 12:50 PM Praha, M. Horákové (Hradčanská) | 18h30 | 7:20 AM Brussels, Brussels South (Gare du Midi) | 1 transfer | |
FlixBus · FlixBus · FlixBus | 12:55 PM Praha, Zličín | 18h25 | 7:20 AM Brussels, Brussels South (Gare du Midi) | 2 transfers | |
FlixBus · FlixBus | 2:30 PM Praha, Černý Most | 16h50 | 7:20 AM Brussels, Brussels South (Gare du Midi) | 1 transfer | |
FlixBus · FlixBus | 4:15 PM Praha, ÚAN Florenc | 17h45 | 10:00 AM Brussels, Gare Du Midi | 1 transfer | |
FlixBus | 4:15 PM Praha, ÚAN Florenc | 15h05 | 7:20 AM Brussels, Brussels South (Gare du Midi) | 0 transfersDirect | |
FlixBus · FlixBus | 5:45 PM Praha, Na Knížecí | 19h00 | 12:45 PM Brussels, Brussels South (Gare du Midi) | 1 transfer | |
FlixBus · FlixBus | 6:00 PM Praha, ÚAN Florenc | 18h25 | 12:25 PM Brussels, Avenue des Magnolias (King Baudouin) | 1 transfer | |
Find all the dates and times for this journey
Compare prices and tickets Prague to Brussels by train, bus, or flight
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Jul 05
Jul 06
Jul 07
Jul 08
Jul 09
Jul 10
Jul 11
Jul 12
Jul 13
Jul 14
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Jul 17
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Jul 23
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Jul 25
Why should you book Prague to Brussels buses with Omio?
Why book with Omio vs FlixBus?
- Compare with other providers: On Omio, you can not only buy tickets for FlixBus, but also compare tickets for the likes of BlaBlaCar Bus to find the best option for your trip from Prague to Brussels.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare FlixBus with all available travel options, which are train, bus and flight to ensure you get the best deal for traveling from Prague to Brussels.
Why book with Omio over Wanderu, Trainline or Checkmybus?
- Compare with other providers: On Omio, you can also compare tickets for the likes of BlaBlaCar Bus to find the best option for your trip from Prague to Brussels.
- Multiple modes of transport: Omio allows you to compare travel options including train, bus and flight to find the ideal travel option from Prague to Brussels.
Journey information
Overview: Bus from Prague to Brussels
Buses from Prague to Brussels run on average 15 times per day, taking around 14h 54m. Cheap bus tickets for this journey start at €40 but you can travel from only €13 by train.
There are 2 buses per day. The earliest bus runs at 00:10, the last at 23:50. The fastest bus covers the 717 km distance in 12h 0m.
Distance 717 km |
Average bus duration 14h 54m |
Cheapest ticket price €40 |
Buses per day 15 |
Direct buses 2 |
Fastest bus 12h 0m |
First bus 12:10 AM |
Last bus 11:50 PM |
Cheapest Month Sep |
Cheapest Day Tue |
High Season Oct - Dec |
Low Season Apr - Jun |
Busiest Day Sun |
Least Busy Day Sat |
Best time to book 84 days |
Bus providers: FlixBus, BlaBlaCar Bus from Prague to BrusselsYou can travel by bus between Prague to Brussels with FlixBus, BlaBlaCar Bus for as low as €13. When you search for schedules and tickets, Omio will show you the best journey
FlixBus
BlaBlaCar Bus
FAQs: Bus from Prague to Brussels
Find answers to the most common questions about traveling from Prague to Brussels by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Brussels, this guide helps you travel smarter and with confidence.

- BlaBlaCar Bus
- Assistance
- Priority boarding
- Accessible seating options.
- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
- BlaBlaCar Bus
- You can cancel your ticket up to 30 minutes before departure for a refund in the form of a voucher.
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
- BlaBlaCar Bus
- One carry-on bag up to 7kg and one checked bag up to 20kg.
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
- BlaBlaCar Bus
- Additional luggage can be purchased for a fee.
- FlixBus
- Additional luggage can be purchased for a fee.
- FlixBus
- Small pets in carriers allowed
- guide dogs travel for free.
popular bus stations
Popular bus stations from Prague to Brussels
Most Prague to Brussels buses use the Praha, ÚAN Florenc to Brussels, Brussels South (Gare du Midi) station pair, with some services arriving at Brussel, Avenue des Magnolias (Koning Boudewijn). Use this guide to compare Prague and Brussels bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Which Prague station do buses to Brussels leave from?
Getting to Praha, ÚAN Florenc from Prague city centre
Praha, ÚAN Florenc is 1 km from Prague city centre. Public transport options include:
Praha, ÚAN Florenc bus station facilities and services
Praha, ÚAN Florenc has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, and Ticket Office.
Food and drink
Food options include: Cafeteria Florenc (in the station), Bistro Florenc (0.2 km), Restaurace U Rozvařilů (0.5 km).
Wi-Fi and ATMs
Free Wi-Fi. ATMs are located inside the station, offering multiple currency options.
Tickets and information
Ticket office support is available at Praha, ÚAN Florenc.
Parking, taxis and toilets
Available at Praha, ÚAN Florenc: Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Praha, ÚAN Florenc: Elevators, ramps.
Getting to Praha, Na Knížecí from Prague city centre
Praha, Na Knížecí is 2 km from Prague city centre. Public transport options include:
Praha, Na Knížecí bus station facilities and services
Praha, Na Knížecí has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, and WC.
Food and drink
Food options include: Café Na Knížecí (in the station), Bistro Praha (0.2 km), Restaurace U Knížete (0.5 km).
Wi-Fi and ATMs
Free Wi-Fi. ATMs are located near the entrance.
Parking, taxis and toilets
Available at Praha, Na Knížecí: Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Praha, Na Knížecí: Elevators, ramps.
Getting to Praha, Hlavní Nádraží from Prague city centre
Praha, Hlavní Nádraží is 1 km from Prague city centre. Public transport options include:
Praha, Hlavní Nádraží bus station facilities and services
Praha, Hlavní Nádraží has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, and Ticket Office.
Food and drink
Food options include: Czech Bistro (in the station), Fast Food Express (in the station), Bohemian Café (0.2 km).
Wi-Fi and ATMs
Free Wi-Fi. ATMs are located near the main entrance and ticketing area.
Tickets and information
Ticket office support is available at Praha, Hlavní Nádraží.
Parking, taxis and toilets
Available at Praha, Hlavní Nádraží: Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Praha, Hlavní Nádraží: Elevators, ramps.
Which Brussels station do buses from Prague arrive at?
Getting to Brussels, Brussels South (Gare du Midi) from Brussels city centre
Brussels, Brussels South (Gare du Midi) is 2 km from Brussels city centre. Public transport options include:
Brussels, Brussels South (Gare du Midi) bus station facilities and services
Brussels, Brussels South (Gare du Midi) has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, and Ticket Office.
Food and drink
Food options include: Cafeteria Midi (in the station), Belgian Bites (in the station), Fritland Express (0.5 km).
Wi-Fi and ATMs
Free Wi-Fi. ATMs are located near the main entrance and throughout the station.
Tickets and information
Ticket office support is available at Brussels, Brussels South (Gare du Midi).
Parking, taxis and toilets
Available at Brussels, Brussels South (Gare du Midi): Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Brussels, Brussels South (Gare du Midi): Elevators, ramps.
Getting to Brussel, Avenue des Magnolias (Koning Boudewijn) from Brussels city centre
Getting to Brussels, Gare Du Midi from Brussels city centre
Most popular bus connections from Prague
More options for your journey from Prague to Brussels
Here are some other resources that might have the information you need



