The cheapest and fastest trains from Prague to Frankfurt am Main
Cheapest price
€68
Average price
€122
Fastest journey
7 h 27 m
Average duration
7 h 27 m
Trains per day
16
Distance
409 km
The best way to find a cheap train ticket from Prague to Frankfurt am Main is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Prague to Frankfurt am Main will cost around €122 if you buy it on the day, but the cheapest tickets can be found for only €68.
It's difficult to get from Prague to Frankfurt am Main without transferring at least 2 times.
R 680 · Os 28013 · S1 · IC 224804:47PM10h03Prague hlavní nádraží02:50AMFrankfurt Airport long-distance station€681One-way5 transfers
RJ 172 · ICE 69904:31PM10h19Prague hlavní nádraží02:50AMFrankfurt Airport long-distance station€801One-way1 transfer
rj 382 · ICE 250610:31AM9h12Prague hlavní nádraží07:43PMFrankfurt (Main) Hbf€911One-way1 transfer
EX 354 · 3433 · ICE 52601:35PM7h27Prague hlavní nádraží09:02PMFrankfurt (Main) Hbf€911One-way2 transfers
EX 354 · 3433 · ICE 52601:35PM7h44Prague hlavní nádraží09:19PMFrankfurt Airport long-distance station€921One-way2 transfers
EX 354 · 3433 · ICE 52601:35PM7h27Prague hlavní nádraží09:02PMFrankfurt (Main) Hbf€911One-way2 transfers
EX 358 · 3568 · ICE 62409:35AM7h27Prague hlavní nádraží05:02PMFrankfurt (Main) Hbf€1141One-way2 transfers
EX 356 · 3572 · ICE 62011:35AM7h27Prague hlavní nádraží07:02PMFrankfurt (Main) Hbf€1141One-way2 transfers
EC 358 · R 3568 · ICE 62409:35AM7h27Prague hlavní nádraží05:02PMFrankfurt (Main) Hbf€1691One-way2 transfers
EC 356 · R 3572 · ICE 62011:35AM7h27Prague hlavní nádraží07:02PMFrankfurt (Main) Hbf€1691One-way2 transfers
Travel Information
Compare train, bus, and flight for Prague to Frankfurt am Main
Omio recommends booking the train as it is the most popular option from Prague to Frankfurt am Main among Omio's users. If you are prioritising price take the bus with prices starting from €23. For those with little time consider booking a flight which can get you there in 2h 33m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.1 - 0.4kg. The ticket price range depends on the travel mode: a bus costs an average of €23, and a flight costs an average of €109.
Distance: 409 km
Compare train with
Most popular Train | Bus | Flight |
|---|---|---|
€82 Average price | €38 Average price Cheapest | €157 Average price |
6h 46m Average total duration 6h 16m Onboard + 30m Additional time* | 7h 46m Average total duration 7h 16m Onboard + 30m Additional time* | 5h 33m Average total duration Fastest 2h 33m Onboard + 3h 0m Additional time* |
0.1 - 0.4kg CO2 emissions Lowest | 0.4 - 1.0kg CO2 emissions | 1.2 - 2.5kg CO2 emissions |
![]() Most popular train company | ![]() Most popular bus company | ![]() Most popular airline |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Live departures
Prague to Frankfurt am Main train times
The table below shows live departures for Prague to Frankfurt am Main trains for today, Monday, March 30. You can also manually refresh the results below to see updated train journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
EX 352 · 3580 · ICE 522 | On time 1:35 PM Prague hlavní nádraží | 7h30 | 9:05 PM Frankfurt (Main) Hbf | 2 transfers | |
EX 352 · 3580 · ICE 522 | On time 1:35 PM Prague hlavní nádraží | 7h47 | 9:22 PM Frankfurt Airport long-distance station | 2 transfers | |
EC 352 · R 3580 · ICE 522 | On time 1:35 PM Prague hlavní nádraží | 7h30 | 9:05 PM Frankfurt (Main) Hbf | 2 transfers | |
EC 458 · S 37588 · ICE 699 | On time 4:31 PM Prague hlavní nádraží | 8h52 | 1:23 AM Frankfurt (Main) Hbf | 2 transfers | |
EN 40458 · R 4650 | On time 4:31 PM Prague hlavní nádraží | 10h53 | 3:24 AM Frankfurt (Main) Hbf | 1 transfer | |
EC 458 · S5 · ICE 699 | On time 4:31 PM Prague hlavní nádraží | 8h52 | 1:23 AM Frankfurt (Main) Hbf | 2 transfers | |
EC 458 · S5 · ICE 699 | On time 4:31 PM Prague hlavní nádraží | 9h08 | 1:39 AM Frankfurt Airport long-distance station | 2 transfers | |
R 676 · Os 28015 · S1 · 16538 | On time 4:47 PM Prague hlavní nádraží | 13h32 | 6:19 AM Frankfurt Airport long-distance station | 5 transfers | |
R 676 · Os 28015 · S1 · 16538 | On time 4:47 PM Prague hlavní nádraží | 12h50 | 5:37 AM Frankfurt (Main) Hbf | 5 transfers | |
R 676 · Os 28015 · S1 · 16538 | On time 4:47 PM Prague hlavní nádraží | 13h57 | 6:44 AM Frankfurt (Main) Hbf | 4 transfers | |
R 676 · Os 28015 · S1 · 16538 | 4:47 PM Prague hlavní nádraží | 13h12 | 5:59 AM Frankfurt am Main Flughafen | 6 transfers | |
| Tuesday, March 31 | |||||
EX 358 · 3568 · ICE 624 | On time 7:35 AM Prague hlavní nádraží | 7h27 | 3:02 PM Frankfurt (Main) Hbf | 2 transfers | |
EX 358 · 3568 · ICE 624 | On time 7:35 AM Prague hlavní nádraží | 7h44 | 3:19 PM Frankfurt Airport long-distance station | 2 transfers | |
EX 358 · ICE 1224 | On time 7:35 AM Prague hlavní nádraží | 8h02 | 3:37 PM Frankfurt (Main) Hbf | 1 transfer | |
EC 358 · R 3568 · ICE 624 | 7:35 AM Prague hlavní nádraží | 7h27 | 3:02 PM Frankfurt (Main) Hbf | 2 transfers | |
RJ 382 · ICE 2506 | On time 8:31 AM Prague hlavní nádraží | 9h12 | 5:43 PM Frankfurt (Main) Hbf | 1 transfer | |
rj 382 · ICE 2506 | On time 8:31 AM Prague hlavní nádraží | 9h12 | 5:43 PM Frankfurt (Main) Hbf | 1 transfer | |
EX 356 · 3572 · ICE 620 | On time 9:35 AM Prague hlavní nádraží | 7h44 | 5:19 PM Frankfurt Airport long-distance station | 2 transfers | |
EX 356 · 3572 · ICE 620 | On time 9:35 AM Prague hlavní nádraží | 7h27 | 5:02 PM Frankfurt (Main) Hbf | 2 transfers | |
EC 356 · R 3572 · ICE 620 | 9:35 AM Prague hlavní nádraží | 7h27 | 5:02 PM Frankfurt (Main) Hbf | 2 transfers | |
RJ 176 · ICE 2504 | On time 10:31 AM Prague hlavní nádraží | 8h49 | 7:20 PM Frankfurt (Main) Hbf | 1 transfer | |
EX 354 · 3433 · ICE 526 | On time 11:35 AM Prague hlavní nádraží | 7h44 | 7:19 PM Frankfurt Airport long-distance station | 2 transfers | |
EX 354 · 3433 · ICE 526 | On time 11:35 AM Prague hlavní nádraží | 7h27 | 7:02 PM Frankfurt (Main) Hbf | 2 transfers | |
EX 354 · ICE 1220 | 11:35 AM Prague hlavní nádraží | 8h02 | 7:37 PM Frankfurt (Main) Hbf | 1 transfer | |
This is the last train of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Prague to Frankfurt am Main by train, bus, or flight
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Mar 30
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Why should you book Prague to Frankfurt am Main trains with Omio?
Why book with Omio vs Deutsche Bahn?
- Compare with other providers: On Omio, you can not only buy tickets for Deutsche Bahn, but also compare tickets for the likes of České dráhy or ÖBB | Euro City (EC) to find the best option for your trip from Prague to Frankfurt am Main.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Deutsche Bahn with all available travel options, which are train, bus and flight to ensure you get the best deal for traveling from Prague to Frankfurt am Main.
Why book with Omio over Trainline, Wanderu or Raileurope?
- Multiple modes of transport: Omio allows you to compare travel options including train, bus and flight to find the ideal travel option from Prague to Frankfurt am Main.
How far in advance should I book train tickets from Prague to Frankfurt am Main?
Journey information
Overview: Train from Prague to Frankfurt am Main
Trains from Prague to Frankfurt am Main run on average 15 times per day, taking around 6h 16m. Cheap train tickets for this journey start at €34 but you can travel from only €23 by bus.
The earliest train runs at 00:01, the last at 23:57. The fastest train covers the 409 km distance in 7h 3m.
Distance 409 km |
Average train duration 6h 16m |
Cheapest ticket price €34 |
Trains per day 15 |
Fastest train 7h 3m |
First train 00:01 |
Last train 23:57 |
Train companies: Deutsche Bahn, České dráhy, ÖBB | Euro City (EC) from Prague to Frankfurt am Main trainsDeutsche Bahn, České dráhy, ÖBB | Euro City (EC) trains will get you between Prague and Frankfurt am Main from €23. With over 1000 travel companies on Omio, you can find the best train times and tickets for your trip.
Deutsche Bahn
A Bordrestaurant (restaurant car) where you can sit and eat.
A Bordbistro (bistro bar) with snacks, hot meals, and drinks to-go.
At-seat service in 1st class: staff will take your order and serve food/drinks directly to your seat.
Regional trains (RE / RB / S-Bahn):
No onboard catering.
You’re welcome to bring your own food and drinks.
Not included by default.
You can add a seat reservation when booking (recommended for busy routes).
Costs around €4.90 per seat (or €5.90 if booked separately later).
First Class:
Yes, always included in the ticket price.
Allowed for free if they can fit in a transport box (max. size: hand luggage).
Must stay in the box for the entire journey.
Large dogs:
Require a separate (paid) ticket — typically half the price of a regular second-class ticket.
Must be leashed and wear a muzzle while on the train.
Cannot sit on seats.
Assistance dogs:
Travel free of charge.
Do not need a muzzle or leash if medically not required.
Allowed to accompany the passenger at all times.
ÖBB | Euro City (EC)
České dráhy
FAQs: Trains from Prague to Frankfurt am Main
Find answers to the most common questions about traveling from Prague to Frankfurt am Main by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Frankfurt am Main, this guide helps you travel smarter and with confidence.

popular train stations
Popular train stations from Prague to Frankfurt am Main
- 6:00 AM - 10:00 PM Monday - Sunday
- Free
- The car park is open 7 days a week, 24 hours a day. Access via Wilsonova Street.
- Restaurant Fantova Kavárna
- Sushi Time
- Outside the main entrance.
- Elevators, ramps.
- CZK 10
- Hotel Esplanade Prague
- Falkensteiner Hotel Maria Prag
- Hotel City Central
- Cost CZK 100
- Located in the main hall
- Located in the main hall
- Avis
- Europcar
- Hertz
- Located in the main hall
- Free
- Hall 1: main entrance, platform 1-7 for trains to Germany, Austria, Slovakia, and regional destinations
- Hall 2: Metro connections
- Metro: Line C
- Tram: Lines 5, 9, 26
- Bus: Several lines available
- 6:00 AM - 10:00 PM Monday - Sunday
- Free
- Parking is available nearby with several public parking options.
- Restaurant Kotleta
- Café Imperial
- Outside the main entrance.
- Ramps.
- CZK 10
- Hotel Kings Court
- Grand Hotel Bohemia
- Hotel Paris Prague
- Located in the main hall
- Avis
- Europcar
- Located in the main hall
- Free
- Hall 1: main entrance, platform 1-5 for regional and suburban trains
- Metro: Line B
- Tram: Lines 3, 5, 14, 24
- Bus: Several lines available
- 6:00 AM - 10:00 PM Monday - Sunday
- Free
- Parking is available 24/7 with access from Partyzánská street.
- Restaurant Na Kovárně
- Cross Club
- Outside the main entrance.
- Ramps, restrooms.
- CZK 10
- Mama Shelter Prague
- Plaza Alta Hotel
- Hotel Belvedere
- Located in the main hall
- Avis
- Budget
- Located in the main hall
- Free
- Hall 1: main entrance, platform 1-4 for trains to Germany, Austria, and regional destinations
- Hall 2: ticket office and waiting area
- Metro: Line C
- Tram: Lines 6, 12, 17
- Bus: Several lines available
- Mon - Fri: 07:00 - 21:00
- Sat - Sun: 09:00 - 21:00
- Free Wi-Fi in the station.
- Luggage lockers are located in the main hall.
- asiagourmet
- Burger King
- Ciao Bella
- Coffee Fellows
- Crepes de France Express
- dean&david
- Starbucks
- Uddin's Sky Sportsbar
- McDonald's
- Dunkin Donuts
- & many more
- Step-free access and step markings. Contact the Mobility Service Centre at +49 3065212888 or [email protected].
- Hotel Cristall
- Grand Hotel Empire
- Hotel Carlton
- Located opposite Platforms 12 and 13.
- 6:00 AM - 10:00 PM Monday - Sunday
- Free
- The car park is open 24/7, accessible via Terminal 1 and Terminal 2 parking areas.
- Restaurant Käfer's
- McDonald's
- Asia Snack Box
- Outside the main entrance.
- Elevators, ramps.
- €1
- Sheraton Frankfurt Airport Hotel
- Hilton Frankfurt Airport
- Hilton Garden Inn Frankfurt Airport
- Cost €6
- Located in the main hall
- Located in the main hall
- Avis
- Europcar
- Hertz
- Located in the main hall
- Free
- Hall 1: main entrance, platform 1-4 for long-distance and regional trains
- Hall 2: connection to Terminal 1 of the airport
- Hall 3: connection to Terminal 2 of the airport
- S-Bahn: Lines S8, S9
- Bus: Several lines available
- Long-distance buses: Available at the airport
- Merals Imbiss
- Bootshaus am Eisernen Steg
- Freigut
- Holbein's
- Hotel am Berg
- Leonardo Royal Hotel Frankfurt
- Hotel Ritter
- Lindner Main Plaza
Most popular train connections from Prague
More options for your journey from Prague to Frankfurt am Main
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