The cheapest and fastest buses from Prague to Frankfurt am Main
Cheapest price
€24
Average price
€46
Fastest journey
5 h
Average duration
5 h 19 m
Buses per day
31
Distance
409 km
The best way to find a cheap bus ticket from Prague to Frankfurt am Main is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Prague to Frankfurt am Main will cost around €46 if you buy it on the day, but the cheapest tickets can be found for only €24.
Of the 31 buses that leave Prague for Frankfurt am Main on Mon, Nov 10, 17 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Mon, Nov 10 the direct buses cover the 409 km distance in an average of 5 h 19 m but if you time it right, some buses will get you there in just 5 h .
On Mon, Nov 10 the slowest buses will take 6 h 25 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.




(Prague -> Amsterdam)



(Prague -> Amsterdam)Travel Information
Compare train, bus, and flight for Prague to Frankfurt am Main
Omio recommends booking the train as it is the most popular option from Prague to Frankfurt am Main among Omio's users. If you are prioritising price take the bus with prices starting from €16. For those with little time consider booking a flight which can get you there in 1h 59m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.1 - 0.4kg. The ticket price range depends on the travel mode: a bus costs an average of €16, and a flight costs an average of €128.
Distance: 409 km
Compare bus with
| Bus | Most popular Train | Flight |
|---|---|---|
€40 Average price Cheapest | €71 Average price | €187 Average price |
12h 1m Average total duration 11h 31m Onboard + 30m Additional time* | 7h 44m Average total duration 7h 14m Onboard + 30m Additional time* | 4h 59m Average total duration Fastest 1h 59m Onboard + 3h 0m Additional time* |
0.4 - 1.0kg CO2 emissions | 0.1 - 0.4kg CO2 emissions Lowest | 1.2 - 2.5kg CO2 emissions |
![]() Most popular bus company | ![]() Most popular train company | ![]() Most popular airline |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Live departures
Prague to Frankfurt am Main bus times
The table below shows live departures for Prague to Frankfurt am Main buses for today, Sunday, November 9. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
FlixBus+ FlixTrain | 6:35 AM Praha, ÚAN Florenc | 9h33 | 4:08 PM Frankfurt South station | 1 transfer | |
FlixBus · FlixBus | 6:35 AM Praha, ÚAN Florenc | 10h20 | 4:55 PM Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36) | 1 transfer | |
FlixBus+ FlixTrain | 6:55 AM Praha, Na Knížecí | 9h13 | 4:08 PM Frankfurt South station | 1 transfer | |
FlixBus | 7:50 AM Praha, ÚAN Florenc | 7h55 | 3:45 PM Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) | 0 transfersDirect | |
FlixBus | 8:10 AM Praha, Na Knížecí | 7h35 | 3:45 PM Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) | 0 transfersDirect | |
FlixBus+ FlixTrain | 8:30 AM Praha, ÚAN Florenc | 10h03 | 6:33 PM Frankfurt South station | 1 transfer | |
FlixBus · FlixBus | 8:55 AM Praha, Zličín | 9h00 | 5:55 PM Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) | 1 transfer | |
FlixBus · FlixBus | 8:55 AM Praha, Zličín | 9h30 | 6:25 PM Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36) | 1 transfer | |
FlixBus | 9:30 AM Praha, ÚAN Florenc | 8h55 | 6:25 PM Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36) | 0 transfersDirect | |
FlixBus | 9:30 AM Praha, ÚAN Florenc | 8h25 | 5:55 PM Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) | 0 transfersDirect | |
FlixBus | 9:55 AM Praha, Na Knížecí | 8h00 | 5:55 PM Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) | 0 transfersDirect | |
FlixBus | 9:55 AM Praha, Na Knížecí | 8h30 | 6:25 PM Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36) | 0 transfersDirect | |
FlixBus | 11:30 AM Praha, ÚAN Florenc | 9h00 | 8:30 PM Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) | 0 transfersDirect | |
FlixBus | 11:50 AM Praha, M. Horákové (Hradčanská) | 8h40 | 8:30 PM Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) | 0 transfersDirect | |
FlixBus · FlixBus | 1:30 PM Praha, Černý Most | 9h50 | 11:20 PM Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36) | 1 transfer | |
FlixBus · FlixBus | 1:30 PM Praha, Černý Most | 9h20 | 10:50 PM Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) | 1 transfer | |
FlixBus · FlixBus | 1:45 PM Prague, Central Train Station | 9h14 | 10:59 PM Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) | 1 transfer | |
FlixBus | 3:15 PM Praha, ÚAN Florenc | 7h35 | 10:50 PM Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) | 0 transfersDirect | |
FlixBus | 3:15 PM Praha, ÚAN Florenc | 8h05 | 11:20 PM Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36) | 0 transfersDirect | |
FlixBus · FlixBus | 4:45 PM Praha, Na Knížecí | 7h25 | 12:10 AM Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) | 1 transfer | |
FlixBus · FlixBus | 4:45 PM Praha, Na Knížecí | 7h50 | 12:35 AM Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36) | 1 transfer | |
FlixBus · FlixBus | 5:45 PM Prague, Central Train Station | 10h50 | 4:35 AM Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36) | 1 transfer | |
FlixBus · FlixBus | 7:15 PM Praha, ÚAN Florenc | 7h45 | 3:00 AM Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) | 1 transfer | |
FlixBus · FlixBus | 7:15 PM Praha, ÚAN Florenc | 9h15 | 4:30 AM Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36) | 1 transfer | |
FlixBus · FlixBus | 7:40 PM Praha, Na Knížecí | 7h20 | 3:00 AM Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) | 1 transfer | |
FlixBus · FlixBus | 7:40 PM Praha, Na Knížecí | 8h50 | 4:30 AM Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36) | 1 transfer | |
FlixBus · FlixBus | 8:55 PM Praha, ÚAN Florenc | 10h20 | 7:15 AM Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) | 1 transfer | |
FlixBus · FlixBus | 9:15 PM Praha, Na Knížecí | 10h00 | 7:15 AM Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) | 1 transfer | |
(Prague -> Amsterdam) | 10:00 PM Praha, ÚAN Florenc | 6h25 | 4:25 AM Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) | 0 transfersDirect | |
| Monday, November 10 | |||||
FlixBus · FlixBus | 2:30 AM Prague, Central Train Station | 11h25 | 1:55 PM Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36) | 1 transfer | |
FlixBus · FlixBus | 2:50 AM Prague, Central Train Station | 11h10 | 2:00 PM Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36) | 1 transfer | |
FlixBus | 2:50 AM Prague, Central Train Station | 7h30 | 10:20 AM Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) | 0 transfersDirect | |
FlixBus | 3:10 AM Praha, Na Knížecí | 7h10 | 10:20 AM Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) | 0 transfersDirect | |
FlixBus · FlixBus | 5:00 AM Praha, ÚAN Florenc | 11h35 | 4:35 PM Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36) | 1 transfer | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Prague to Frankfurt am Main by train, bus, or flight
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Nov 29
Journey information
Overview: Bus from Prague to Frankfurt am Main
Buses from Prague to Frankfurt am Main run on average 32 times per day, taking around 11h 31m. Cheap bus tickets for this journey start at €16 if you book in advance.
There are 13 buses per day. The earliest bus runs at 00:05, the last at 23:50. The fastest bus covers the 409 km distance in 6h 25m.
Distance 409 km |
Average bus duration 11h 31m |
Cheapest ticket price €16 |
Buses per day 32 |
Direct buses 13 |
Fastest bus 6h 25m |
First bus 00:05 |
Last bus 23:50 |
Bus providers: FlixBus, BlaBlaCar Bus, BlaBlaCar, Infobus from Prague to Frankfurt am MainYou can travel by bus between Prague to Frankfurt am Main with FlixBus, BlaBlaCar Bus, BlaBlaCar, Infobus for as low as €16. When you search for schedules and tickets, Omio will show you the best journey
FlixBus
Infobus
BlaBlaCar Bus
BlaBlaCar
FAQs: Bus from Prague to Frankfurt am Main
Find answers to the most common questions about traveling from Prague to Frankfurt am Main by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Frankfurt am Main, this guide helps you travel smarter and with confidence.

Passengers board the coach most frequently from Prague, Central Train Station, which is located around 1.8 miles (2.9 km) away from the city centre, and they get off the coach at Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36), located 8.4 miles (13.6 km) away from the city centre.
To find the cheapest bus tickets for your trip from Prague to Frankfurt am Main, follow these tips:
Start your search now and compare ticket prices to find the best deal!
popular bus stations
Popular bus stations from Prague to Frankfurt am Main
- Free Wi-Fi
- Café Na Knížecí (in the station)
- Bistro Praha (0.2 km)
- Restaurace U Knížete (0.5 km).
- Available outside the main entrance.
- Elevators, ramps
- Available in the station.
- Bus: 137, 176, 191 Metro: B
- 00:00-23:59
- Free Wi-Fi
- Czech Bistro (in the station)
- Fast Food Express (in the station)
- Bohemian Café (0.2 km).
- Available outside the main entrance.
- Elevators, ramps
- Available in the station.
- Bus: 135, 175, 207 Metro: C Train: All major s
- 06:00-23:00
- Free Wi-Fi
- Cafeteria Florenc (in the station)
- Bistro Florenc (0.2 km)
- Restaurace U Rozvařilů (0.5 km).
- Available outside the main entrance.
- Elevators, ramps
- Available in the station.
- Bus: 133, 135, 175, 207 Metro: B, C
- 00:00-23:59
- Free Wi-Fi
- Cafeteria Černý Most (in the station)
- Czech Bistro (in the station)
- Fast Food Express (in the station).
- Available outside the main entrance.
- Elevators, ramps
- Available in the station.
- Bus: 177, 195, 201 Metro: B
- Bus: 131, 174, 180 Metro: A Train: S4, S5
- 00:00-23:59
- Free Wi-Fi
- McDonald's (in the station)
- Hausmann's (in the station).
- Available outside the terminal at designated taxi stands.
- Elevators, ramps, assistance
- Available in the station.
- Bus: 61, 62, 77 Train: S8, S9
- 06:00-22:00
- Free Wi-Fi
- Bakery & Café (in the station)
- Fast Food Express (in the station)
- Available outside the main entrance.
- Elevators, ramps
- Available in the station.
- Bus: 61, 78 Train: S3, S4, S5, S6 Tram: 15, 16
Most popular bus connections from Prague
More options for your journey from Prague to Frankfurt am Main
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