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Compare bus, train, and flight for Frankfurt am Main to Prague
Omio recommends booking the train as it is the most popular option from Frankfurt am Main to Prague among Omio's users. If you are prioritising price take the bus with prices starting from €13. For those with little time consider booking a flight which can get you there in 3h 19m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.1 - 0.4kg. The ticket price range depends on the travel mode: a bus costs an average of €13, and a flight costs an average of €144.
Distance: 409 km
Compare train with
Most popular Train | Bus | Flight |
|---|---|---|
€95 Average price | €36 Average price Cheapest | €228 Average price |
6h 32m Average total duration 6h 2m Onboard + 30m Additional time* | 7h 36m Average total duration 7h 6m Onboard + 30m Additional time* | 6h 19m Average total duration Fastest 3h 19m Onboard + 3h 0m Additional time* |
0.1 - 0.4kg CO2 emissions Lowest | 0.4 - 1.0kg CO2 emissions | 1.2 - 2.5kg CO2 emissions |
![]() Most popular train company | ![]() Most popular bus company | ![]() Most popular airline |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Travel optionsfrom Frankfurt am Main to Prague
How to get from Frankfurt am Main to Prague by train, bus or flight.
Our recommendation
The best way to travel from Frankfurt am Main to Prague is by taking a bus because it’s the best combination of price and speed.
439п5:30 PM14h20Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof)7:50 AMPraha, ÚAN Florenc€351One-way0 transfers
Cheapest
439п5:30 PM14h20Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof)7:50 AMPraha, ÚAN Florenc€351One-way0 transfers
Fastest
DE44118:25 PM1h00Frankfurt am Main Airport9:25 PMPrague Vaclav Havel Airport€1441One-way0 transfers
Other options
EC 45912:28 AM8h57Frankfurt South station9:25 AMPrague hlavní nádraží€511One-way0 transfers
ICE 1559 · rj 17711:19 AM7h56Frankfurt (Main) Hbf7:15 PMPrague-Holešovice€531One-way1 transfer
ICE 523 · 3461+
3556:57 AM7h24Frankfurt (Main) Hbf2:21 PMPrague hlavní nádraží€591One-way2 transfers
439п5:05 PM14h45Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36)7:50 AMPraha, ÚAN Florenc€351One-way0 transfers
(Amsterdam -> Prague)10:30 PM6h15Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof)4:45 AMPrague, Central Train Station€401One-way0 transfers
(Amsterdam -> Prague)10:30 PM6h18Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof)4:48 AMPraha, ÚAN Florenc€401One-way0 transfers
DE44073:00 PM1h00Frankfurt am Main Airport4:00 PMPrague Vaclav Havel Airport€1441One-way0 transfers
DE44099:20 AM1h00Frankfurt am Main Airport10:20 AMPrague Vaclav Havel Airport€1441One-way0 transfers
LO380 · LO5277:50 PM16h15Frankfurt am Main Airport12:05 PMPrague Vaclav Havel Airport€2691One-way1 transfer
Find all the dates and times for this journey by train, bus, flight, and ferry .
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FAQs: Travel from Frankfurt am Main to Prague
Travel to Prague easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Frankfurt am Main to Prague.

This is compared to other travel options from Frankfurt am Main to Prague:
A bus is €60 less than a train for this route with tickets for a train from Frankfurt am Main to Prague costing on average €95.
A bus is €193 less than a flight for this route with tickets for a flight from Frankfurt am Main to Prague costing on average €228.
Other travel options to Prague take longer:
Train takes on average 6h 2m.
Bus takes on average 7h 6m.
- Around 47 flights per day.
- Around 30 buses per day.
- Around 16 trains per day.
However, we recommend checking specific travel dates for your route between Frankfurt am Main and Prague as scheduled services by bus, train, and flight can vary by season or day of the week.
- Flights mostly depart from Frankfurt am Main Airport and arrive in Prague Vaclav Havel Airport.
- Trains mostly depart from Frankfurt (Main) Hbf and arrive in Prague hlavní nádraží.
- Buses mostly depart from Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) and arrive in Praha, ÚAN Florenc.
- Travel with Deutsche Bahn, alex-Länderbahn und Vogtlandbahn-GmbH, České dráhy, Leo Express, FlixTrain to go to Prague by train.
- Travel with Lufthansa, Condor Flugdienst, Air Dolomiti, Lot Polish Airlines, KLM, Lufthansa Cityline, Brussels Airlines, KLM Cityhopper, Austrian Airlines to go to Prague by flight.
- Travel with FlixBus, KLR, Infobus, BlaBlaCar Bus, BlaBlaCar to go to Prague by bus.
- 7 direct flights per day with Lufthansa, Condor Flugdienst, Air Dolomiti.
- 14 direct buses per day with FlixBus, KLR, Infobus, BlaBlaCar Bus, BlaBlaCar.
Travelling from Frankfurt am Main to Prague: related information
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