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Compare train, bus, and flight for Frankfurt am Main to Prague
Omio recommends booking the train as it is the most popular option from Frankfurt am Main to Prague among Omio's users. If you are prioritising price take the bus with prices starting from €12. For those with little time consider booking a flight which can get you there in 3h 19m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.1 - 0.4kg. The ticket price range depends on the travel mode: a bus costs an average of €12, and a flight costs an average of €131.
Distance: 409 km
Compare train with
Most popular Train | Bus | Flight |
|---|---|---|
€88 Average price | €35 Average price Cheapest | €209 Average price |
6h 2m Average total duration 5h 32m Onboard + 30m Additional time* | 7h 45m Average total duration 7h 15m Onboard + 30m Additional time* | 6h 19m Average total duration Fastest 3h 19m Onboard + 3h 0m Additional time* |
0.1 - 0.4kg CO2 emissions Lowest | 0.4 - 1.0kg CO2 emissions | 1.2 - 2.5kg CO2 emissions |
![]() Most popular train company | ![]() Most popular bus company | ![]() Most popular airline |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Travel optionsfrom Frankfurt am Main to Prague
How to get from Frankfurt am Main to Prague by train, bus or flight.
Our recommendation
The best way to travel from Frankfurt am Main to Prague is by taking a bus because it’s the best combination of price and speed.
FlixBus03:20PM7h00Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof)10:20PMPraha, ÚAN Florenc€541One-way0 transfers
Cheapest
FlixBus · FlixBus02:45AM10h00Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof)12:45PMPraha, Na Knížecí€531One-way1 transfer
Fastest
DE440708:25PM1h00Frankfurt am Main Airport09:25PMPrague Vaclav Havel Airport€1771One-way0 transfers
Other options
ICE 527 · 3565+
35708:57AM7h24Frankfurt (Main) Hbf04:21PMPrague hlavní nádraží€1441One-way2 transfers
ICE 527 · 3565+
35708:41AM7h40Frankfurt Airport long-distance station04:21PMPrague hlavní nádraží€1441One-way2 transfers
ICE 629 · 3577+
36302:41PM7h41Frankfurt Airport long-distance station10:22PMPrague hlavní nádraží€1441One-way2 transfers
FlixBus05:05PM7h00Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof)12:05AMPraha, Na Knížecí€541One-way0 transfers
FlixBus01:00PM8h10Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof)09:10PMPraha, Na Knížecí€611One-way0 transfers
FlixBus10:40AM8h30Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36)07:10PMPraha, Na Knížecí€681One-way0 transfers
DE440903:00PM1h00Frankfurt am Main Airport04:00PMPrague Vaclav Havel Airport€1891One-way0 transfers
DE441110:00AM1h00Frankfurt am Main Airport11:00AMPrague Vaclav Havel Airport€2021One-way0 transfers
LH139612:30PM1h00Frankfurt am Main Airport01:30PMPrague Vaclav Havel Airport€3081One-way0 transfers
Find all the dates and times for this journey by train, bus, flight, and ferry .
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FAQs: Travel from Frankfurt am Main to Prague
Travel to Prague easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Frankfurt am Main to Prague.

This is compared to other travel options from Frankfurt am Main to Prague:
A bus is €26 less than a train for this route with tickets for a train from Frankfurt am Main to Prague costing on average €37.
A bus is €119 less than a flight for this route with tickets for a flight from Frankfurt am Main to Prague costing on average €131.
Other travel options to Prague take longer:
Train takes on average 7h 0m.
Bus takes on average 6h 18m.
- Around 44 flights per day.
- Around 29 buses per day.
- Around 16 trains per day.
However, we recommend checking specific travel dates for your route between Frankfurt am Main and Prague as scheduled services by train, bus, and flight can vary by season or day of the week.
- Flights mostly depart from Frankfurt am Main Airport and arrive in Prague Vaclav Havel Airport.
- Trains mostly depart from Frankfurt (Main) Hbf and arrive in Prague hlavní nádraží.
- Buses mostly depart from Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36) and arrive in Praha, ÚAN Florenc.
- Travel with Deutsche Bahn, alex-Länderbahn und Vogtlandbahn-GmbH, České dráhy, FlixTrain, ÖBB to go to Prague by train.
- Travel with Lufthansa, Condor Flugdienst, Air Dolomiti, LOT Polish Airlines, KLM, Lufthansa Cityline, Brussels Airlines, KLM Cityhopper, Austrian Airlines to go to Prague by flight.
- Travel with FlixBus, KLR, Infobus, BlaBlaCar Bus, BlaBlaCar to go to Prague by bus.
- 0 direct trains per day with ÖBB.
- 7 direct flights per day with Lufthansa, Condor Flugdienst, Air Dolomiti.
- 14 direct buses per day with FlixBus, KLR, BlaBlaCar Bus, BlaBlaCar.
Travelling from Frankfurt am Main to Prague: related information
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