Travel Information
Compare train, bus, and flight for Lyon to Brussels
Omio recommends booking the train as it is the most popular option from Lyon to Brussels among Omio's users. If you are prioritising price take the bus with prices starting from €22. For those with little time consider booking a flight which can get you there in 2h 25m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.2 - 0.5kg. The ticket price range depends on the travel mode: a bus costs an average of €22, and a flight costs an average of €92.
Distance: 569 km
Compare train with
Most popular Train | Bus | Flight |
|---|---|---|
€131 Average price | €48 Average price Cheapest | €251 Average price |
5h 17m Average total duration 4h 47m Onboard + 30m Additional time* | 8h 29m Average total duration 7h 59m Onboard + 30m Additional time* | 5h 25m Average total duration Fastest 2h 25m Onboard + 3h 0m Additional time* |
0.2 - 0.5kg CO2 emissions Lowest | 0.6 - 1.4kg CO2 emissions | 1.7 - 3.4kg CO2 emissions |
![]() Most popular train company | ![]() Most popular bus company | ![]() Most popular airline |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Travel optionsfrom Lyon to Brussels
How to get from Lyon to Brussels by train, bus or flight.
Our recommendation
The best way to travel from Lyon to Brussels is by taking a bus because it’s the best combination of price and speed.
50884 · 503215:00 AM10h15Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)3:15 PMBrussels, Brussels South (Gare du Midi)€501One-way1 transfer
Cheapest
50884 · 503215:00 AM10h15Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)3:15 PMBrussels, Brussels South (Gare du Midi)€501One-way1 transfer
Fastest
SN35881:10 PM1h25Lyon Saint Exupery Airport2:35 PMBrussels Airport€2281One-way0 transfers
Other options
98525:50 AM3h53Lyon Part Dieu9:43 AMBrussels-Midi€851One-way0 transfers
6690+
93597:04 AM10h13Lyon Part Dieu5:17 PMBrussels-Midi€1171One-way1 transfer
6618+
94891:04 PM9h13Lyon Part Dieu10:17 PMBrussels-Midi€1191One-way1 transfer
94742 · 16571:30 AM10h30Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)12:00 PMBrussels, Brussels South (Gare du Midi)€501One-way1 transfer
50756 · 14073:35 AM11h10Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)2:45 PMBrussels, Brussels South (Gare du Midi)€501One-way1 transfer
50756 · 16613:35 AM11h10Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)2:45 PMBrussels, Brussels South (Gare du Midi)€501One-way1 transfer
SN35947:05 AM1h25Lyon Saint Exupery Airport8:30 AMBrussels Airport€2281One-way0 transfers
VY1221 · VY89829:50 AM7h35Lyon Saint Exupery Airport5:25 PMBrussels Airport€2671One-way1 transfer
LH2247+
LH55809:30 AM3h40Lyon Saint Exupery Airport1:10 PMBrussels Airport€2871One-way1 transfer
Find all the dates and times for this journey by train, bus, flight, and ferry .
Compare prices and tickets Prices for trains, buses and flights
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FAQs: Travel from Lyon to Brussels
Travel to Brussels easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Lyon to Brussels.

This is compared to other travel options from Lyon to Brussels:
A bus is €84 less than a train for this route with tickets for a train from Lyon to Brussels costing on average €131.
A bus is €204 less than a flight for this route with tickets for a flight from Lyon to Brussels costing on average €251.
Other travel options to Brussels take longer:
Train takes on average 4h 47m.
Bus takes on average 7h 59m.
- Around 14 buses per day.
- Around 12 flights per day.
- Around 4 trains per day.
However, we recommend checking specific travel dates for your route between Lyon and Brussels as scheduled services by train, bus, and flight can vary by season or day of the week.
- Flights mostly depart from Lyon Saint Exupery Airport and arrive in Brussels Airport.
- Trains mostly depart from Lyon Part Dieu and arrive in Brussels-Midi.
- Buses mostly depart from Lyon, Perrache Bus Station and arrive in Brussels, Brussels South (Gare du Midi).
- Travel with Brussels Airlines, Air Baltic, Lufthansa, Vueling, Austrian Airlines, KLM, Swiss, easyJet to go to Brussels by flight.
- Travel with BlaBlaCar Bus, FlixBus, BlaBlaCar, Alsa to go to Brussels by bus.
- Travel with SNCF | TGV INOUI, TGV to go to Brussels by train.
- 2 direct flights per day with Brussels Airlines, Air Baltic, Swiss, easyJet.
- 3 direct buses per day with BlaBlaCar Bus, FlixBus, BlaBlaCar.
- 4 direct trains per day with SNCF | TGV INOUI, TGV.
Travelling from Lyon to Brussels: related information
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