The cheapest and fastest buses from Brindisi to Palermo
Cheapest price
€109
Average price
€122
Fastest journey
11 h 50 m
Average duration
11 h 58 m
Buses per day
2
Distance
482 km
The best way to find a cheap bus ticket from Brindisi to Palermo is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Brindisi to Palermo will cost around €122 if you buy it on the day, but the cheapest tickets can be found for only €109.
Of the 2 buses that leave Brindisi for Palermo on Thu, Aug 13, 1 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Thu, Aug 13 the direct buses cover the 482 km distance in an average of 11 h 58 m but if you time it right, some buses will get you there in just 11 h 50 m .
On Thu, Aug 13 the slowest buses will take 12 h 5 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
FlixBus11:10 PM12h05Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale)11:15 AMPalermo, Via Tommaso Fazello (Terminal Bus)€1091One-way0 transfers
FlixBus · FlixBus11:10 PM11h50Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale)11:00 AMPalermo, Via Tommaso Fazello (Terminal Bus)€1361One-way1 transfer
FlixBus · FlixBus11:10 PM11h50Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale)11:00 AMPalermo, Via Tommaso Fazello (Terminal Bus)€1361One-way1 transfer
FlixBus11:10 PM12h05Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale)11:15 AMPalermo, Via Tommaso Fazello (Terminal Bus)€1091One-way0 transfers
Travel Information
Compare bus, train, and flight for Brindisi to Palermo
Omio recommends booking the flight as it is the most popular option from Brindisi to Palermo among Omio's users. If you are prioritising price take the train with prices starting from €26. For those with little time consider booking a flight which can get you there in 1h 33m. The ticket price range depends on the travel mode: a train costs an average of €26, and a flight costs an average of €106.
Distance: 482 km
Compare bus with
| Bus | Most popular Flight | Train |
|---|---|---|
€84 Average price | €140 Average price | €59 Average price Cheapest |
11h 50m Average total duration 11h 20m Onboard + 30m Additional time* | 4h 33m Average total duration Fastest 1h 33m Onboard + 3h 0m Additional time* | 15h 32m Average total duration 15h 2m Onboard + 30m Additional time* |
![]() Most popular bus company | ![]() Most popular airline | ![]() Most popular train company |
Direct Options | Direct Options | Direct Options |
Live departures
Brindisi to Palermo bus times
The table below shows live departures for Brindisi to Palermo buses for tomorrow, Thursday, August 13. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
FlixBus | 11:10 PM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) | 12h05 | 11:15 AM Palermo, Via Tommaso Fazello (Terminal Bus) | 0 transfersDirect | |
FlixBus · FlixBus | 11:10 PM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) | 11h50 | 11:00 AM Palermo, Via Tommaso Fazello (Terminal Bus) | 1 transfer | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Brindisi to Palermo by bus, train, or flight
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Why should you book Brindisi to Palermo buses with Omio?
Why book with Omio vs FlixBus?
- Compare with other providers: On Omio, you can not only buy tickets for FlixBus, but also compare tickets for the likes of Sais Autolinee to find the best option for your trip from Brindisi to Palermo.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare FlixBus with all available travel options, which are bus, train and flight to ensure you get the best deal for traveling from Brindisi to Palermo.
Why book with Omio over Wanderu, Trainline or Checkmybus?
- Compare with other providers: On Omio, you can also compare tickets for the likes of Sais Autolinee to find the best option for your trip from Brindisi to Palermo.
- Multiple modes of transport: Omio allows you to compare travel options including bus, train and flight to find the ideal travel option from Brindisi to Palermo.
Journey information
Overview: Bus from Brindisi to Palermo
Buses from Brindisi to Palermo run on average 1 times per day, taking around 11h 20m. Cheap bus tickets for this journey start at €40 but you can travel from only €26 by train.
The earliest bus runs at 04:21, the last at 23:50. The fastest bus covers the 482 km distance in 25h 15m.
Distance 482 km |
Average bus duration 11h 20m |
Cheapest ticket price €40 |
Buses per day 1 |
Fastest bus 25h 15m |
First bus 4:21 AM |
Last bus 11:50 PM |
Cheapest Month Jul |
Cheapest Day Tue |
High Season Jul - Sep |
Low Season Jan - Mar |
Busiest Day Sun |
Least Busy Day Tue |
Best time to book 5 days |
Bus providers: FlixBus, Sais Autolinee, BlaBlaCar from Brindisi to PalermoYou can travel by bus between Brindisi to Palermo with FlixBus, Sais Autolinee, BlaBlaCar for as low as €26. When you search for schedules and tickets, Omio will show you the best journey
FlixBus
Sais Autolinee
BlaBlaCar
FAQs: Bus from Brindisi to Palermo
Find answers to the most common questions about traveling from Brindisi to Palermo by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Palermo, this guide helps you travel smarter and with confidence.

- Sais Autolinee
- Assistance
- Priority boarding
- Accessible seating.
- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
- Sais Autolinee
- You can cancel your ticket up to 24 hours before departure for a partial refund. No refunds for cancellations within 24 hours.
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
- Sais Autolinee
- One carry-on bag up to 10kg and one checked bag up to 20kg.
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
- Sais Autolinee
- Additional luggage can be purchased for a fee.
- FlixBus
- Additional luggage can be purchased for a fee.
- Sais Autolinee
- Small pets allowed in carriers
- larger pets must be leashed and muzzled.
- FlixBus
- Small pets in carriers allowed
- guide dogs travel for free.
popular bus stations
Popular bus stations from Brindisi to Palermo
Most Brindisi to Palermo buses use the Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) to Palermo, Via Tommaso Fazello (Terminal Bus) station pair. Use this guide to compare Brindisi and Palermo bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Most popular bus connections from Brindisi
More options for your journey from Brindisi to Palermo
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