The cheapest and fastest buses from Milan to Palermo
- Cheapest price on Nov 12
- €79
- Average ticket price on Nov 12
- €91
- Fastest journey on Nov 12
- 21 h 55 m
- Average journey duration on Nov 12
- 23 h 43 m
- Buses on Nov 12
- 4
- Distance
- 887 km
The best way to find a cheap bus ticket from Milan to Palermo is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Milan to Palermo will cost around €91 if you buy it on the day, but the cheapest tickets can be found for only €79.
On Thu, Nov 12, we found 4 buses from Milan to Palermo, including 1 direct services.
On Thu, Nov 12 the direct buses cover the 887 km distance in an average of 23 h 43 m but if you time it right, some buses will get you there in just 21 h 55 m .
On Thu, Nov 12 the slowest buses will take 1 d 1 h 35 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
FlixBus · FlixBus6:30 PM 24h50 Milano, San Donato - Settore B (Viale Giuseppe Impastato) 7:20 PM Palermo, Via Tommaso Fazello (Terminal Bus) €79 1 One-way 1 transfer
FlixBus1:05 PM 21h55 Milano, Autostazione Lampugnano 11:00 AM Palermo, Via Tommaso Fazello (Terminal Bus) €92 1 One-way 0 transfers
FlixBus · FlixBus12:30 PM 22h30 Milano, San Donato - Settore B (Viale Giuseppe Impastato) 11:00 AM Palermo, Via Tommaso Fazello (Terminal Bus) €93 1 One-way 1 transfer
FlixBus · FlixBus5:45 PM 25h35 Milano, Autostazione Lampugnano 7:20 PM Palermo, Via Tommaso Fazello (Terminal Bus) €98 1 One-way 1 transfer
FlixBus1:05 PM 21h55 Milano, Autostazione Lampugnano 11:00 AM Palermo, Via Tommaso Fazello (Terminal Bus) €92 1 One-way 0 transfers
FlixBus · FlixBus12:30 PM 22h30 Milano, San Donato - Settore B (Viale Giuseppe Impastato) 11:00 AM Palermo, Via Tommaso Fazello (Terminal Bus) €93 1 One-way 1 transfer
FlixBus · FlixBus6:30 PM 24h50 Milano, San Donato - Settore B (Viale Giuseppe Impastato) 7:20 PM Palermo, Via Tommaso Fazello (Terminal Bus) €79 1 One-way 1 transfer
FlixBus · FlixBus5:45 PM 25h35 Milano, Autostazione Lampugnano 7:20 PM Palermo, Via Tommaso Fazello (Terminal Bus) €98 1 One-way 1 transfer
Journey information
Overview: Bus from Milan to Palermo
Buses from Milan to Palermo run on average 7 times per day, taking around 22h 7m. Cheap bus tickets for this journey start at €28 but you can travel from only €17 by flight.
There are 1 buses per day. The earliest bus runs at 00:52, the last at 22:45. The fastest bus covers the 887 km distance in 20h 30m.
Distance 887 km |
Average bus duration 22h 7m |
Cheapest ticket price €28 |
Buses per day 7 |
Direct buses 1 |
Fastest bus 20h 30m |
First bus 12:52 AM |
Last bus 10:45 PM |
Cheapest Month Sep |
Cheapest Day Mon |
High Season Jul - Sep |
Low Season Jan - Mar |
Busiest Day Fri |
Least Busy Day Sat |
Best time to book 91 days |
Frequently asked questions about your Milan to Palermo trip
Use these quick route answers to check fares, travel time, departure options, and direct services before booking from Milan to Palermo.
Live departures
Milan to Palermo bus times
The table below shows live departures for Milan to Palermo buses for today, Wednesday, November 11. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
FlixBus · FlixBus · FlixBus | 11:05 PM Sesto San Giovanni, Piazza Primo Maggio (Stazione ferroviaria) | 35h55 | 11:00 AM Palermo, Via Tommaso Fazello (Terminal Bus) | 2 transfers | |
| Thursday, November 12 | |||||
FlixBus · FlixBus | 12:30 PM Milano, San Donato - Settore B (Viale Giuseppe Impastato) | 22h30 | 11:00 AM Palermo, Via Tommaso Fazello (Terminal Bus) | 1 transfer | |
FlixBus | 1:05 PM Milano, Autostazione Lampugnano | 21h55 | 11:00 AM Palermo, Via Tommaso Fazello (Terminal Bus) | 0 transfersDirect | |
FlixBus · FlixBus | 5:45 PM Milano, Autostazione Lampugnano | 25h35 | 7:20 PM Palermo, Via Tommaso Fazello (Terminal Bus) | 1 transfer | |
FlixBus · FlixBus | 6:30 PM Milano, San Donato - Settore B (Viale Giuseppe Impastato) | 24h50 | 7:20 PM Palermo, Via Tommaso Fazello (Terminal Bus) | 1 transfer | |
Find all the dates and times for this journey
Why should you book Milan to Palermo buses with Omio?
Why book with Omio vs FlixBus?
- Compare with other providers: On Omio, you can not only buy tickets for FlixBus, but also compare tickets for the likes of Itabus or Salemi to find the best option for your trip from Milan to Palermo.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare FlixBus with all available travel options, which are train, bus, flight and ferry to ensure you get the best deal for traveling from Milan to Palermo.
Why book with Omio over Wanderu, Trainline or Checkmybus?
- Compare with other providers: On Omio, you can also compare tickets for the likes of Itabus or Salemi to find the best option for your trip from Milan to Palermo.
- Multiple modes of transport: Omio allows you to compare travel options including train, bus, flight and ferry to find the ideal travel option from Milan to Palermo.
Bus providers: FlixBus, Salemi, Itabus from Milan to PalermoYou can travel by bus between Milan to Palermo with FlixBus, Salemi, Itabus for as low as €17. When you search for schedules and tickets, Omio will show you the best journey
FlixBus
Itabus
Salemi
Companies, tickets, and onboard amenities between Milan and Palermo
Review the details behind your booking, from operators and ticket rules to luggage, onboard amenities, accessibility, and route-specific travel policies.
- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
- Itabus
- Assistance
- Dedicated seating areas
- Accessible restrooms.
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
- Itabus
- You can cancel your ticket up to 24 hours before departure for a partial refund. Changes allowed for a fee.
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
- Itabus
- One carry-on bag up to 10kg and one checked bag up to 20kg.
- FlixBus
- Additional luggage can be purchased for a fee.
- Itabus
- 5€ per additional bag.
- FlixBus
- Small pets in carriers allowed
- guide dogs travel for free.
- Itabus
- Small pets allowed in carriers
- larger pets must be leashed and muzzled.
FAQs: Bus from Milan to Palermo
Find answers to the most common questions about traveling from Milan to Palermo by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Palermo, this guide helps you travel smarter and with confidence.

popular bus stations
Popular bus stations from Milan to Palermo
Most Milan to Palermo buses use the Milano, Autostazione Lampugnano to station pair. Use this guide to compare Milan and Palermo bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Which Milan station do buses to Palermo leave from?
Getting to Milano, Autostazione Lampugnano from Milan city centre
Milano, Autostazione Lampugnano is 5 km from Milan city centre. Public transport options include:
Milano, Autostazione Lampugnano bus station facilities and services
Milano, Autostazione Lampugnano has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, and Ticket Office.
Food and drink
Food options include: Cafeteria Lampugnano (in the station), Trattoria Milano (0.5 km), Pizza Express (0.7 km).
Wi-Fi and ATMs
Free Wi-Fi. ATMs are located near the main entrance.
Tickets and information
Ticket office support is available at Milano, Autostazione Lampugnano.
Parking, taxis and toilets
Available at Milano, Autostazione Lampugnano: Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Milano, Autostazione Lampugnano: Elevators, ramps.
Getting to Milano, San Donato - Settore B (Viale Giuseppe Impastato) from Milan city centre
Milano, San Donato - Settore B (Viale Giuseppe Impastato) is 6 km from Milan city centre. Public transport options include:
Milano, San Donato - Settore B (Viale Giuseppe Impastato) bus station facilities and services
Milano, San Donato - Settore B (Viale Giuseppe Impastato) has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, and Ticket Office.
Food and drink
Food options include: Cafeteria Italiana (in the station), Fast Food Express (in the station), Trattoria Milano (0.5 km).
Wi-Fi and ATMs
Free Wi-Fi. ATMs are located near the main entrance for cash withdrawals.
Tickets and information
Ticket office support is available at Milano, San Donato - Settore B (Viale Giuseppe Impastato).
Parking, taxis and toilets
Available at Milano, San Donato - Settore B (Viale Giuseppe Impastato): Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Milano, San Donato - Settore B (Viale Giuseppe Impastato): Elevators, ramps.
Getting to Milano, Aeroporto di Milano Linate from Milan city centre
More options for your journey from Milan to Palermo
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