The cheapest and fastest buses from Milan to Palermo
Cheapest price
€88
Average price
€114
Fastest journey
21 h
Average duration
21 h 45 m
Buses per day
9
Distance
887 km
The best way to find a cheap bus ticket from Milan to Palermo is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Milan to Palermo will cost around €114 if you buy it on the day, but the cheapest tickets can be found for only €88.
Of the 9 buses that leave Milan for Palermo on Fri, May 15, 1 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Fri, May 15 the direct buses cover the 887 km distance in an average of 21 h 45 m but if you time it right, some buses will get you there in just 21 h .
On Fri, May 15 the slowest buses will take 22 h 15 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
700 · S20110:45 AM21h00Milano, San Donato M37:45 AMPalermo, Via Tommaso Fazello (Terminal Bus)€881One-way1 transfer
700 · S20110:00 AM21h45Milano, Autostazione Lampugnano7:45 AMPalermo, Via Tommaso Fazello (Terminal Bus)€881One-way1 transfer
FlixBus · FlixBus · FlixBus10:20 AM28h55Milano, Milan Linate Airport3:15 PMPalermo, Via Tommaso Fazello (Terminal Bus)€981One-way2 transfers
FlixBus · FlixBus5:25 PM21h50Milano, San Donato - Settore B (Viale Giuseppe Impastato)3:15 PMPalermo, Via Tommaso Fazello (Terminal Bus)€1191One-way1 transfer
FlixBus · FlixBus4:40 PM22h35Milano, Autostazione Lampugnano3:15 PMPalermo, Via Tommaso Fazello (Terminal Bus)€1191One-way1 transfer
700 · S20110:45 AM21h00Milano, San Donato M37:45 AMPalermo, Via Tommaso Fazello (Terminal Bus)€881One-way1 transfer
700 · S20110:00 AM21h45Milano, Autostazione Lampugnano7:45 AMPalermo, Via Tommaso Fazello (Terminal Bus)€881One-way1 transfer
FlixBus · FlixBus5:25 PM21h50Milano, San Donato - Settore B (Viale Giuseppe Impastato)3:15 PMPalermo, Via Tommaso Fazello (Terminal Bus)€1191One-way1 transfer
FlixBus1:05 PM21h55Milano, Autostazione Lampugnano11:00 AMPalermo, Via Tommaso Fazello (Terminal Bus)€1211One-way0 transfers
FlixBus · FlixBus12:45 PM22h15Milano, San Donato - Settore B (Viale Giuseppe Impastato)11:00 AMPalermo, Via Tommaso Fazello (Terminal Bus)€1261One-way1 transfer
Travel Information
Compare train, bus, flight, and ferry for Milan to Palermo
Omio recommends booking the flight as it is the most popular option from Milan to Palermo among Omio's users. If you are prioritising price take the ferry with prices starting from €66. For those with little time consider booking a flight which can get you there in 1h 51m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.3 - 0.8kg. The ticket price range depends on the travel mode: a ferry costs an average of €66, and a flight costs an average of €17.
Distance: 887 km
Compare bus with
| Bus | Most popular Flight | Train | Ferry |
|---|---|---|---|
€90 Average price | €123 Average price | €123 Average price | €72 Average price Cheapest |
20h 50m Average total duration 20h 20m Onboard + 30m Additional time* | 4h 51m Average total duration Fastest 1h 51m Onboard + 3h 0m Additional time* | 16h 38m Average total duration 16h 8m Onboard + 30m Additional time* | 21h 3m Average total duration 20h 3m Onboard + 1h 0m Additional time* |
0.9 - 2.2kg CO2 emissions | 2.7 - 5.3kg CO2 emissions | 0.3 - 0.8kg CO2 emissions Lowest | - CO2 emissions |
![]() Most popular bus company | ![]() Most popular airline | ![]() Most popular train company | ![]() Most popular ferry company |
Direct Options | Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Live departures
Milan to Palermo bus times
The table below shows live departures for Milan to Palermo buses for today, Thursday, May 14. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 9:05 PM Milan | 35h55 | 9:00 AM Palermo | 0 transfersDirect | |
![]() | 10:05 PM Milan | 35h55 | 10:00 AM Palermo | 0 transfersDirect | |
| Friday, May 15 | |||||
700 · S201 | 10:00 AM Milano, Autostazione Lampugnano | 21h45 | 7:45 AM Palermo, Via Tommaso Fazello (Terminal Bus) | 1 transfer | |
FlixBus · FlixBus · FlixBus | 10:20 AM Milano, Milan Linate Airport | 28h55 | 3:15 PM Palermo, Via Tommaso Fazello (Terminal Bus) | 2 transfers | |
700 · S201 | 10:45 AM Milano, San Donato M3 | 21h00 | 7:45 AM Palermo, Via Tommaso Fazello (Terminal Bus) | 1 transfer | |
FlixBus · FlixBus | 12:45 PM Milano, San Donato - Settore B (Viale Giuseppe Impastato) | 22h15 | 11:00 AM Palermo, Via Tommaso Fazello (Terminal Bus) | 1 transfer | |
FlixBus | 1:05 PM Milano, Autostazione Lampugnano | 21h55 | 11:00 AM Palermo, Via Tommaso Fazello (Terminal Bus) | 0 transfersDirect | |
FlixBus · FlixBus | 4:40 PM Milano, Autostazione Lampugnano | 22h35 | 3:15 PM Palermo, Via Tommaso Fazello (Terminal Bus) | 1 transfer | |
FlixBus · FlixBus | 5:25 PM Milano, San Donato - Settore B (Viale Giuseppe Impastato) | 21h50 | 3:15 PM Palermo, Via Tommaso Fazello (Terminal Bus) | 1 transfer | |
FlixBus · FlixBus | 5:45 PM Milano, Autostazione Lampugnano | 25h35 | 7:20 PM Palermo, Via Tommaso Fazello (Terminal Bus) | 1 transfer | |
FlixBus · FlixBus | 6:30 PM Milano, San Donato - Settore B (Viale Giuseppe Impastato) | 24h50 | 7:20 PM Palermo, Via Tommaso Fazello (Terminal Bus) | 1 transfer | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Milan to Palermo by train, bus, flight, or ferry
Compare train, bus, flight, and ferry prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
May 14
May 15
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May 19
May 20
May 21
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May 29
May 30
May 31
Jun 01
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Jun 03
Why should you book Milan to Palermo buses with Omio?
Why book with Omio vs FlixBus?
- Compare with other providers: On Omio, you can not only buy tickets for FlixBus, but also compare tickets for the likes of Autoservizi Salemi, Itabus, Salemi or Infobus to find the best option for your trip from Milan to Palermo.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare FlixBus with all available travel options, which are train, bus, flight and ferry to ensure you get the best deal for traveling from Milan to Palermo.
Why book with Omio over Wanderu, Trainline or Checkmybus?
- Compare with other providers: On Omio, you can also compare tickets for the likes of Autoservizi Salemi, Itabus, Salemi or Infobus to find the best option for your trip from Milan to Palermo.
- Multiple modes of transport: Omio allows you to compare travel options including train, bus, flight and ferry to find the ideal travel option from Milan to Palermo.
Journey information
Overview: Bus from Milan to Palermo
Buses from Milan to Palermo run on average 6 times per day, taking around 20h 20m. Cheap bus tickets for this journey start at €54 but you can travel from only €17 by flight.
There are 1 buses per day. The earliest bus runs at 00:52, the last at 22:45. The fastest bus covers the 887 km distance in 21h 45m.
Distance 887 km |
Average bus duration 20h 20m |
Cheapest ticket price €54 |
Buses per day 6 |
Direct buses 1 |
Fastest bus 21h 45m |
First bus 12:52 AM |
Last bus 10:45 PM |
Cheapest Month Mar |
Cheapest Day Sat |
High Season Jul - Sep |
Low Season Jan - Mar |
Busiest Day Tue |
Least Busy Day Sat |
Best time to book 35 days |
Bus providers: FlixBus, Autoservizi Salemi, Itabus, Salemi, BlaBlaCar, Infobus from Milan to PalermoYou can travel by bus between Milan to Palermo with FlixBus, Autoservizi Salemi, Itabus, Salemi, BlaBlaCar, Infobus for as low as €17. When you search for schedules and tickets, Omio will show you the best journey
FlixBus
Itabus
Infobus
Autoservizi Salemi
Salemi
BlaBlaCar
FAQs: Bus from Milan to Palermo
Find answers to the most common questions about traveling from Milan to Palermo by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Palermo, this guide helps you travel smarter and with confidence.

- Infobus
- Assistance
- Priority seating
- Transport for wheelchairs and mobility aids.
- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
- Itabus
- Assistance
- Dedicated seating areas
- Accessible restrooms.
- Autoservizi Salemi
- The cancellation policy can vary by ticket class, individual trips, or promotions, so it's best to check the terms during booking.
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
- Itabus
- You can cancel your ticket up to 24 hours before departure for a partial refund. Changes allowed for a fee.
- Autoservizi Salemi
- Two pieces of luggage: one large suitcase for the hold and one smaller backpack for on-board.
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
- Itabus
- One carry-on bag up to 10kg and one checked bag up to 20kg.
- Infobus
- 10€ per additional bag.
- FlixBus
- Additional luggage can be purchased for a fee.
- Itabus
- 5€ per additional bag.
- Infobus
- Small pets allowed in carriers
- larger pets may require a separate ticket.
- FlixBus
- Small pets in carriers allowed
- guide dogs travel for free.
- Itabus
- Small pets allowed in carriers
- larger pets must be leashed and muzzled.
popular bus stations
Popular bus stations from Milan to Palermo
- 06:00-23:00
- Free Wi-Fi
- Cafeteria Lampugnano (in the station)
- Trattoria Milano (0.5 km)
- Pizza Express (0.7 km).
- Available outside the station.
- Elevators, ramps
- Available in the station.
- Metro: M1 Bus: 68, 78, 80
- 06:00-22:00
- Free Wi-Fi
- Cafeteria Italiana (in the station)
- Fast Food Express (in the station)
- Trattoria Milano (0.5 km).
- Available outside the station.
- Elevators, ramps
- Available in the station.
- Bus: 121, 132 Metro: M3
Most popular bus connections from Milan
More options for your journey from Milan to Palermo
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