The cheapest and fastest buses from Rome to Palermo
- Cheapest price on Nov 12
- €40
- Average ticket price on Nov 12
- €46
- Fastest journey on Nov 12
- 11 h 45 m
- Average journey duration on Nov 12
- 15 h 48 m
- Buses on Nov 12
- 2
- Distance
- 427 km
The best way to find a cheap bus ticket from Rome to Palermo is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Rome to Palermo will cost around €46 if you buy it on the day, but the cheapest tickets can be found for only €40.
On Thu, Nov 12, we found 2 buses from Rome to Palermo, including 1 direct services.
On Thu, Nov 12 the direct buses cover the 427 km distance in an average of 15 h 48 m but if you time it right, some buses will get you there in just 11 h 45 m .
On Thu, Nov 12 the slowest buses will take 19 h 50 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
FlixBus · FlixBus11:30 PM 19h50 Roma, Autostazione Tiburtina 7:20 PM Palermo, Via Tommaso Fazello (Terminal Bus) €40 1 One-way 1 transfer
S2018:00 PM 11h45 Roma, Autostazione Tiburtina 7:45 AM Palermo, Via Tommaso Fazello (Terminal Bus) €51 1 One-way 0 transfers
S2018:00 PM 11h45 Roma, Autostazione Tiburtina 7:45 AM Palermo, Via Tommaso Fazello (Terminal Bus) €51 1 One-way 0 transfers
FlixBus · FlixBus11:30 PM 19h50 Roma, Autostazione Tiburtina 7:20 PM Palermo, Via Tommaso Fazello (Terminal Bus) €40 1 One-way 1 transfer
Journey information
Overview: Bus from Rome to Palermo
Buses from Rome to Palermo run on average 4 times per day, taking around 13h 57m. Cheap bus tickets for this journey start at €17 if you book in advance.
There are 1 buses per day. The earliest bus runs at 00:45, the last at 23:45. The fastest bus covers the 427 km distance in 11h 45m.
Distance 427 km |
Average bus duration 13h 57m |
Cheapest ticket price €17 |
Buses per day 4 |
Direct buses 1 |
Fastest bus 11h 45m |
First bus 12:45 AM |
Last bus 11:45 PM |
Cheapest Month Sep |
Cheapest Day Sat |
High Season Jul - Sep |
Low Season Jan - Mar |
Busiest Day Wed |
Least Busy Day Mon |
Best time to book 91 days |
Frequently asked questions about your Rome to Palermo trip
Use these quick route answers to check fares, travel time, departure options, and direct services before booking from Rome to Palermo.
Live departures
Rome to Palermo bus times
The table below shows live departures for Rome to Palermo buses for today, Wednesday, November 11. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
S201 | 8:00 PM Roma, Autostazione Tiburtina | 11h45 | 7:45 AM Palermo, Via Tommaso Fazello (Terminal Bus) | 0 transfersDirect | |
FlixBus · FlixBus | 11:30 PM Roma, Autostazione Tiburtina | 19h50 | 7:20 PM Palermo, Via Tommaso Fazello (Terminal Bus) | 1 transfer | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Why should you book Rome to Palermo buses with Omio?
Why book with Omio vs Salemi?
- Compare with other providers: On Omio, you can not only buy tickets for Salemi, but also compare tickets for the likes of FlixBus or Itabus to find the best option for your trip from Rome to Palermo.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Salemi with all available travel options, which are train, bus, flight and ferry to ensure you get the best deal for traveling from Rome to Palermo.
Why book with Omio over Checkmybus, Wanderu or Trainline?
- Compare with other providers: On Omio, you can also compare tickets for the likes of FlixBus or Itabus to find the best option for your trip from Rome to Palermo.
- Multiple modes of transport: Omio allows you to compare travel options including train, bus, flight and ferry to find the ideal travel option from Rome to Palermo.
Bus providers: FlixBus, Salemi, Itabus from Rome to PalermoYou can travel by bus between Rome to Palermo with FlixBus, Salemi, Itabus for as low as €17. When you search for schedules and tickets, Omio will show you the best journey
FlixBus
Itabus
Salemi
Companies, tickets, and onboard amenities between Rome and Palermo
Review the details behind your booking, from operators and ticket rules to luggage, onboard amenities, accessibility, and route-specific travel policies.
- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
- Itabus
- Assistance
- Dedicated seating areas
- Accessible restrooms.
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
- Itabus
- You can cancel your ticket up to 24 hours before departure for a partial refund. Changes allowed for a fee.
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
- Itabus
- One carry-on bag up to 10kg and one checked bag up to 20kg.
- FlixBus
- Additional luggage can be purchased for a fee.
- Itabus
- 5€ per additional bag.
- FlixBus
- Small pets in carriers allowed
- guide dogs travel for free.
- Itabus
- Small pets allowed in carriers
- larger pets must be leashed and muzzled.
FAQs: Bus from Rome to Palermo
Find answers to the most common questions about traveling from Rome to Palermo by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Palermo, this guide helps you travel smarter and with confidence.

popular bus stations
Popular bus stations from Rome to Palermo
Most Rome to Palermo buses use the Roma, Autostazione Tiburtina to station pair. Use this guide to compare Rome and Palermo bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Which Rome station do buses to Palermo leave from?
Getting to Roma, Autostazione Tiburtina from Rome city centre
Roma, Autostazione Tiburtina is 4 km from Rome city centre. Public transport options include:
Roma, Autostazione Tiburtina bus station facilities and services
Roma, Autostazione Tiburtina has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food and drink
Food options include: Cafes and vending machines available.
Wi-Fi and ATMs
Wi-Fi is available at Roma, Autostazione Tiburtina. ATMs are aTM available near ticket office.
Tickets and information
Ticket office support is available at Roma, Autostazione Tiburtina.
Parking, taxis and toilets
Available at Roma, Autostazione Tiburtina: Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Roma, Autostazione Tiburtina: Wheelchair accessible entrances and facilities.
Getting to Fiumicino, Aeroporto Leonardo de Vinci (T3 Arrivi - Stazione degli autobus) from Rome city centre
Fiumicino, Aeroporto Leonardo de Vinci (T3 Arrivi - Stazione degli autobus) is 3 km from Rome city centre. Public transport options include:
Fiumicino, Aeroporto Leonardo de Vinci (T3 Arrivi - Stazione degli autobus) bus station facilities and services
Fiumicino, Aeroporto Leonardo de Vinci (T3 Arrivi - Stazione degli autobus) has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, and Ticket Office.
Food and drink
Food options include: Ristorante Italiano (in the station), Fast Food Express (in the station), Caffè del Terminal (in the station).
Wi-Fi and ATMs
Free Wi-Fi. ATMs are located near the arrivals area.
Tickets and information
Ticket office support is available at Fiumicino, Aeroporto Leonardo de Vinci (T3 Arrivi - Stazione degli autobus).
Parking, taxis and toilets
Available at Fiumicino, Aeroporto Leonardo de Vinci (T3 Arrivi - Stazione degli autobus): Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Fiumicino, Aeroporto Leonardo de Vinci (T3 Arrivi - Stazione degli autobus): Elevators, ramps.
Getting to Roma, Autostazione (Metro Anagnina) from Rome city centre
More options for your journey from Rome to Palermo
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