The cheapest and fastest buses from Brussels to Prague
Cheapest price
€61
Average price
€78
Fastest journey
13 h 35 m
Average duration
16 h 7 m
Buses per day
9
Distance
717 km
The best way to find a cheap bus ticket from Brussels to Prague is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Brussels to Prague will cost around €78 if you buy it on the day, but the cheapest tickets can be found for only €61.
Of the 9 buses that leave Brussels for Prague on Fri, Nov 28, 1 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Fri, Nov 28 the direct buses cover the 717 km distance in an average of 16 h 7 m but if you time it right, some buses will get you there in just 13 h 35 m .
On Fri, Nov 28 the slowest buses will take 17 h 50 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
FlixBus · FlixBus
4740 · 30512
FlixBus · FlixBus · FlixBus
FlixBus · FlixBus
FlixBus · FlixBus
4740 · 30512
FlixBus
FlixBus · FlixBus
FlixBus · FlixBus
FlixBus · FlixBusTravel Information
Compare train, bus, and flight for Brussels to Prague
Omio recommends booking the flight as it is the most popular option from Brussels to Prague among Omio's users. If you are prioritising price take the bus with prices starting from €22. For those with little time consider booking a flight which can get you there in 2h 25m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.2 - 0.6kg. The ticket price range depends on the travel mode: a bus costs an average of €22, and a flight costs an average of €30.
Distance: 717 km
Compare bus with
| Bus | Most popular Flight | Train |
|---|---|---|
€57 Average price Cheapest | €189 Average price | €166 Average price |
15h 41m Average total duration 15h 11m Onboard + 30m Additional time* | 5h 25m Average total duration Fastest 2h 25m Onboard + 3h 0m Additional time* | 12h 54m Average total duration 12h 24m Onboard + 30m Additional time* |
0.7 - 1.8kg CO2 emissions | 2.2 - 4.3kg CO2 emissions | 0.2 - 0.6kg CO2 emissions Lowest |
![]() Most popular bus company | ![]() Most popular airline | ![]() Most popular train company |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Live departures
Brussels to Prague bus times
The table below shows live departures for Brussels to Prague buses for today, Thursday, November 27. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
FlixBus · FlixBus | 2:45 PM Brussels, Avenue des Magnolias (King Baudouin) | 18h55 | 9:40 AM Praha, ÚAN Florenc | 1 transfer | |
FlixBus · FlixBus | 3:15 PM Brussels, Brussels South (Gare du Midi) | 16h40 | 7:55 AM Praha, Na Knížecí | 1 transfer | |
FlixBus · FlixBus · FlixBus | 3:15 PM Brussels, Brussels South (Gare du Midi) | 19h15 | 10:30 AM Prague, Central Train Station | 2 transfers | |
FlixBus | 3:15 PM Brussels, Brussels South (Gare du Midi) | 14h40 | 5:55 AM Praha, ÚAN Florenc | 0 transfersDirect | |
FlixBus · FlixBus | 3:40 PM Brussels, Brussels South (Gare du Midi) | 17h25 | 9:05 AM Praha, Na Knížecí | 1 transfer | |
(London -> Prague) | 5:30 PM Brussels, Brussels South (Gare du Midi) | 11h55 | 5:25 AM Praha, ÚAN Florenc | 0 transfersDirect | |
FlixBus · FlixBus · FlixBus | 7:15 PM Brussels, Brussels South (Gare du Midi) | 20h30 | 3:45 PM Prague, Central Train Station | 2 transfers | |
FlixBus · FlixBus | 11:45 PM Brussels, Brussels South (Gare du Midi) | 19h15 | 7:00 PM Prague, Central Train Station | 1 transfer | |
| Friday, November 28 | |||||
FlixBus · FlixBus | 12:20 AM Brussels, Brussels South (Gare du Midi) | 17h50 | 6:10 PM Praha, ÚAN Florenc | 1 transfer | |
FlixBus · FlixBus | 12:20 AM Brussels, Brussels South (Gare du Midi) | 17h50 | 6:10 PM Praha, Na Knížecí | 1 transfer | |
Find all the dates and times for this journey
Compare prices and tickets Brussels to Prague by train, bus, or flight
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Nov 28
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Journey information
Overview: Bus from Brussels to Prague
Buses from Brussels to Prague run on average 24 times per day, taking around 15h 11m. Cheap bus tickets for this journey start at €22 if you book in advance.
There are 3 buses per day. The earliest bus runs at 00:10, the last at 23:50. The fastest bus covers the 717 km distance in 11h 55m.
Distance 717 km |
Average bus duration 15h 11m |
Cheapest ticket price €22 |
Buses per day 24 |
Direct buses 3 |
Fastest bus 11h 55m |
First bus 00:10 |
Last bus 23:50 |
Bus providers: FlixBus, BlaBlaCar Bus, Infobus from Brussels to PragueYou can travel by bus between Brussels to Prague with FlixBus, BlaBlaCar Bus, Infobus for as low as €22. When you search for schedules and tickets, Omio will show you the best journey
FlixBus
Infobus
BlaBlaCar Bus
FAQs: Bus from Brussels to Prague
Find answers to the most common questions about traveling from Brussels to Prague by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Prague, this guide helps you travel smarter and with confidence.

Passengers board the coach most frequently from Bruxelles, Gare du Nord, which is located around 1.1 miles (1.7 km) away from the city centre, and they get off the coach at Prague, Central Train Station, located 1.8 miles (2.9 km) away from the city centre.
To find the cheapest bus tickets for your trip from Brussels to Prague, follow these tips:
Start your search now and compare ticket prices to find the best deal!
popular bus stations
Popular bus stations from Brussels to Prague
- 06:00-23:59
- Free Wi-Fi
- Cafeteria Noord (in the station)
- Quick Brussels Noord (in the station)
- Le Pain Quotidien (0.5 km).
- Available outside the main entrance.
- Elevators, ramps
- Available in the station.
- Bus: 14, 57, 58 Metro: 2, 6 Train: IC, S1, S2
- 06:00-23:00
- Free Wi-Fi
- Cafeteria Midi (in the station)
- Belgian Bites (in the station)
- Fritland Express (0.5 km).
- Available outside the main entrance.
- Elevators, ramps
- Available in the station.
- Bus: 27, 49, 50, 78 Metro: 2, 6 Train: IC, S, Thalys, Eurostar
- The place has an entrance that is wheelchair-accessible
- Free Wi-Fi
- Café Na Knížecí (in the station)
- Bistro Praha (0.2 km)
- Restaurace U Knížete (0.5 km).
- Available outside the main entrance.
- Elevators, ramps
- Available in the station.
- Bus: 137, 176, 191 Metro: B
- 00:00-23:59
- Free Wi-Fi
- Czech Bistro (in the station)
- Fast Food Express (in the station)
- Bohemian Café (0.2 km).
- Available outside the main entrance.
- Elevators, ramps
- Available in the station.
- Bus: 135, 175, 207 Metro: C Train: All major s
- 06:00-23:00
- Free Wi-Fi
- Cafeteria Florenc (in the station)
- Bistro Florenc (0.2 km)
- Restaurace U Rozvařilů (0.5 km).
- Available outside the main entrance.
- Elevators, ramps
- Available in the station.
- Bus: 133, 135, 175, 207 Metro: B, C
- 00:00-23:59
- Free Wi-Fi
- Cafeteria Černý Most (in the station)
- Czech Bistro (in the station)
- Fast Food Express (in the station).
- Available outside the main entrance.
- Elevators, ramps
- Available in the station.
- Bus: 177, 195, 201 Metro: B
- Bus: 131, 174, 180 Metro: A Train: S4, S5
Most popular bus connections from Brussels
More options for your journey from Brussels to Prague
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