The cheapest and fastest buses from Brussels to Prague
Cheapest price
€56
Average price
€71
Fastest journey
11 h 50 m
Average duration
14 h 35 m
Buses per day
7
Distance
717 km
The best way to find a cheap bus ticket from Brussels to Prague is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Brussels to Prague will cost around €71 if you buy it on the day, but the cheapest tickets can be found for only €56.
Of the 7 buses that leave Brussels for Prague on Thu, Feb 26, 3 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Thu, Feb 26 the direct buses cover the 717 km distance in an average of 14 h 35 m but if you time it right, some buses will get you there in just 11 h 50 m .
On Thu, Feb 26 the slowest buses will take 17 h 50 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
(London -> Prague)
(London -> Prague)
FlixBus
FlixBus · FlixBus · FlixBus
FlixBus · FlixBus
(London -> Prague)
(London -> Prague)
FlixBus
FlixBus · FlixBus
FlixBus · FlixBusTravel Information
Compare train, bus, and flight for Brussels to Prague
Omio recommends booking the flight as it is the most popular option from Brussels to Prague among Omio's users. If you are prioritising price take the bus with prices starting from €40. For those with little time consider booking a flight which can get you there in 2h 6m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.2 - 0.6kg. The ticket price range depends on the travel mode: a bus costs an average of €40, and a flight costs an average of €20.
Distance: 717 km
Compare bus with
| Bus | Most popular Flight | Train |
|---|---|---|
€66 Average price Cheapest | €116 Average price | €116 Average price |
15h 58m Average total duration 15h 28m Onboard + 30m Additional time* | 5h 6m Average total duration Fastest 2h 6m Onboard + 3h 0m Additional time* | 13h 15m Average total duration 12h 45m Onboard + 30m Additional time* |
0.7 - 1.8kg CO2 emissions | 2.2 - 4.3kg CO2 emissions | 0.2 - 0.6kg CO2 emissions Lowest |
![]() Most popular bus company | ![]() Most popular airline | ![]() Most popular train company |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Live departures
Brussels to Prague bus times
The table below shows live departures for Brussels to Prague buses for today, Wednesday, February 25. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
FlixBus · FlixBus | 3:15 PM Brussels, Brussels South (Gare du Midi) | 17h50 | 9:05 AM Praha, Na Knížecí | 1 transfer | |
FlixBus | 3:15 PM Brussels, Brussels South (Gare du Midi) | 14h40 | 5:55 AM Praha, ÚAN Florenc | 0 transfersDirect | |
| Thursday, February 26 | |||||
FlixBus · FlixBus | 12:20 AM Brussels, Brussels South (Gare du Midi) | 17h50 | 6:10 PM Praha, Na Knížecí | 1 transfer | |
FlixBus · FlixBus | 12:20 AM Brussels, Brussels South (Gare du Midi) | 18h15 | 6:35 PM Praha, ÚAN Florenc | 1 transfer | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Brussels to Prague by train, bus, or flight
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Feb 25
Feb 26
Feb 27
Feb 28
Mar 01
Mar 02
Mar 03
Mar 04
Mar 05
Mar 06
Mar 07
Mar 08
Mar 09
Mar 10
Mar 11
Mar 12
Mar 13
Mar 14
Mar 15
Mar 16
Mar 17
Why should you book Brussels to Prague buses with Omio?
Why book with Omio vs FlixBus?
- Compare with other providers: On Omio, you can not only buy tickets for FlixBus, but also compare tickets for the likes of BlaBlaCar Bus or Infobus to find the best option for your trip from Brussels to Prague.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare FlixBus with all available travel options, which are train, bus and flight to ensure you get the best deal for traveling from Brussels to Prague.
Why book with Omio over Wanderu, Trainline or Checkmybus?
- Compare with other providers: On Omio, you can also compare tickets for the likes of BlaBlaCar Bus or Infobus to find the best option for your trip from Brussels to Prague.
- Multiple modes of transport: Omio allows you to compare travel options including train, bus and flight to find the ideal travel option from Brussels to Prague.
Journey information
Overview: Bus from Brussels to Prague
Buses from Brussels to Prague run on average 18 times per day, taking around 15h 28m. Cheap bus tickets for this journey start at €42 but you can travel from only €20 by flight.
There are 2 buses per day. The earliest bus runs at 00:10, the last at 23:50. The fastest bus covers the 717 km distance in 11h 50m.
Distance 717 km |
Average bus duration 15h 28m |
Cheapest ticket price €42 |
Buses per day 18 |
Direct buses 2 |
Fastest bus 11h 50m |
First bus 00:10 |
Last bus 23:50 |
Bus providers: FlixBus, BlaBlaCar Bus, Infobus from Brussels to PragueYou can travel by bus between Brussels to Prague with FlixBus, BlaBlaCar Bus, Infobus for as low as €15. When you search for schedules and tickets, Omio will show you the best journey
FlixBus
Infobus
BlaBlaCar Bus
FAQs: Bus from Brussels to Prague
Find answers to the most common questions about traveling from Brussels to Prague by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Prague, this guide helps you travel smarter and with confidence.

- Infobus
- Assistance
- Priority seating
- Transport for wheelchairs and mobility aids.
- BlaBlaCar Bus
- Assistance
- Priority boarding
- Accessible seating options.
- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
- Infobus
- You can cancel your ticket up to 24 hours before departure for a partial refund. Cancellations within 24 hours may incur a fee.
- BlaBlaCar Bus
- You can cancel your ticket up to 30 minutes before departure for a refund in the form of a voucher.
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
- Infobus
- One carry-on bag up to 5kg (40x20x25) and one checked bag up to 20kg (50x30x80).
- BlaBlaCar Bus
- One carry-on bag up to 7kg and one checked bag up to 20kg.
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
- Infobus
- 10€ per additional bag.
- BlaBlaCar Bus
- Additional luggage can be purchased for a fee.
- FlixBus
- Additional luggage can be purchased for a fee.
- Infobus
- Small pets allowed in carriers
- larger pets may require a separate ticket.
- FlixBus
- Small pets in carriers allowed
- guide dogs travel for free.
popular bus stations
Popular bus stations from Brussels to Prague
- 06:00-23:00
- Free Wi-Fi
- Cafeteria Midi (in the station)
- Belgian Bites (in the station)
- Fritland Express (0.5 km).
- Available outside the main entrance.
- Elevators, ramps
- Available in the station.
- Bus: 27, 49, 50, 78 Metro: 2, 6 Train: IC, S, Thalys, Eurostar
- 06:00-23:59
- Free Wi-Fi
- Cafeteria Noord (in the station)
- Quick Brussels Noord (in the station)
- Le Pain Quotidien (0.5 km).
- Available outside the main entrance.
- Elevators, ramps
- Available in the station.
- Bus: 14, 57, 58 Metro: 2, 6 Train: IC, S1, S2
- 06:00-23:00
- Free Wi-Fi
- Cafeteria Florenc (in the station)
- Bistro Florenc (0.2 km)
- Restaurace U Rozvařilů (0.5 km).
- Available outside the main entrance.
- Elevators, ramps
- Available in the station.
- Bus: 133, 135, 175, 207 Metro: B, C
- 00:00-23:59
- Free Wi-Fi
- Czech Bistro (in the station)
- Fast Food Express (in the station)
- Bohemian Café (0.2 km).
- Available outside the main entrance.
- Elevators, ramps
- Available in the station.
- Bus: 135, 175, 207 Metro: C Train: All major s
- Free Wi-Fi
- Café Na Knížecí (in the station)
- Bistro Praha (0.2 km)
- Restaurace U Knížete (0.5 km).
- Available outside the main entrance.
- Elevators, ramps
- Available in the station.
- Bus: 137, 176, 191 Metro: B
Most popular bus connections from Brussels
More options for your journey from Brussels to Prague
Here are some other resources that might have the information you need


