Pisa to Madrid bus with FlixBus

Sat, Mar 14
+ Add return
FlixBus
Lirosi Linee
Regiojet
Alsa
National Express
1,000+ travel companies
FlixBus
Lirosi Linee
Regiojet
Alsa
National Express
1,000+ travel companies
QR-Code
Scan to get our free app
Use our app to get live travel updates and book mobile tickets for trains, buses, flights, and ferries.
App Store
rate4.9
42K ratings
Google Play
rate4.6
136K reviews

The cheapest and fastest buses from Pisa to Madrid

Showing times and prices for Mar 14

Cheapest price

€85

Average price

€118

Fastest journey

1 d 4 h 5 m

Average duration

1 d 12 h 3 m

Buses per day

4

Distance

1219 km

Cheap tickets

The best way to find a cheap bus ticket from Pisa to Madrid is to book your journey as far in advance as possible and to avoid traveling at rush hour.

The average ticket from Pisa to Madrid will cost around €118 if you buy it on the day, but the cheapest tickets can be found for only €85.

Fast buses

It's difficult to get from Pisa to Madrid without transferring at least once.

FlixBusFlixBus · FlixBus · FlixBus
10:00PM36h30
Pisa, Via delle Fiamme Gialle (Park Pietrasantina)
10:30AMMadrid, Estación Sur de Autobuses
851One-way
2 transfers
FlixBusFlixBus · FlixBus
06:25AM28h05
Pisa, Via delle Fiamme Gialle (Park Pietrasantina)
10:30AMMadrid, Estación Sur de Autobuses
941One-way
1 transfer
FlixBusFlixBus · FlixBus · FlixBus
04:45PM40h10
Pisa, Via delle Fiamme Gialle (Park Pietrasantina)
08:55AMMadrid, Estación Sur de Autobuses
1161One-way
2 transfers
FlixBusFlixBus · FlixBus · FlixBus
04:45PM39h25
Pisa, Via delle Fiamme Gialle (Park Pietrasantina)
08:10AMMadrid, Terminal de autobuses T4 (Aeropuerto de Madrid)
1781One-way
2 transfers

Travel Information

Compare train, bus, and flight for Pisa to Madrid

Omio recommends booking the flight as it is the most popular option from Pisa to Madrid among Omio's users. If you are prioritising price take the bus with prices starting from €42. For those with little time consider booking a flight which can get you there in 3h 38m. In case you are seeking to minimise your carbon footprint the bus is your best bet as it emits only 1.2 - 3.0kg. The ticket price range depends on the travel mode: a bus costs an average of €42, and a train costs an average of €274.

Distance: 1219 km

Compare bus with

Bus
Most popular
Flight
Train

€138

Average price

Cheapest

€146

Average price

€274

Average price

23h 19m

Average total duration

22h 49m

Onboard

+

30m

Additional time*

6h 38m

Average total duration

Fastest

3h 38m

Onboard

+

3h 0m

Additional time*

29h 6m

Average total duration

28h 36m

Onboard

+

30m

Additional time*

1.2 - 3.0kg

CO2 emissions

Lowest

3.7 - 7.3kg

CO2 emissions

-

CO2 emissions

Direct Options

Direct Options

Direct Options

Additional time: Average total travel duration to departure point, security checks and transfers.

Live departures

Pisa to Madrid bus times

The table below shows live departures for Pisa to Madrid buses for today, Friday, March 13. You can also manually refresh the results below to see updated bus journeys.

Last updated at 1:29 PM
ProviderDepartsDurationArrivesTransfers
Tickets
meinfernbus_flixbusFlixBus · FlixBus · FlixBus9:00 PM Pisa, Via delle Fiamme Gialle (Park Pietrasantina)
36h30
9:30 AM Madrid, Estación Sur de Autobuses2 transfers
Saturday, March 14
meinfernbus_flixbusFlixBus · FlixBus5:25 AM Pisa, Via delle Fiamme Gialle (Park Pietrasantina)
28h05
9:30 AM Madrid, Estación Sur de Autobuses1 transfer

This is the last bus of the day.

Find all the dates and times for this journey

Compare prices and tickets Pisa to Madrid by train, bus, or flight

Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.

Fri
Mar 13
Sat
Mar 14
Sun
Mar 15
Mon
Mar 16
Tue
Mar 17
Wed
Mar 18
Thu
Mar 19
Fri
Mar 20
Sat
Mar 21
Sun
Mar 22
Mon
Mar 23
Tue
Mar 24
Wed
Mar 25
Thu
Mar 26
Fri
Mar 27
Sat
Mar 28
Sun
Mar 29
Mon
Mar 30
Tue
Mar 31
Wed
Apr 01
Thu
Apr 02

Why should you book Pisa to Madrid buses with Omio?

FlixBus as well as Lirosi Linee offer buses services from Pisa to Madrid.
Omio is an official ticket reseller for all your travel options from Pisa to Madrid.

Why book with Omio vs FlixBus?

  • Compare with other providers: On Omio, you can not only buy tickets for FlixBus, but also compare tickets for the likes of Lirosi Linee to find the best option for your trip from Pisa to Madrid.
  • Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
  • Compare all your options: Omio allows you to compare FlixBus with all available travel options, which are train, bus and flight to ensure you get the best deal for traveling from Pisa to Madrid.

Why book with Omio over Wanderu or Trainline?

  • Multiple modes of transport: Omio allows you to compare travel options including train, bus and flight to find the ideal travel option from Pisa to Madrid.

Journey information

Overview: Bus from Pisa to Madrid

ItalyItaly
SpainSpain
Icon of bus

Buses from Pisa to Madrid run on average 5 times per day, taking around 22h 49m. Cheap bus tickets for this journey start at €42 but you can travel from only €32 by flight.

The earliest bus runs at 00:25, the last at 23:50. The fastest bus covers the 1219 km distance in 27h 15m.

Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Flight from €32
Distance
1219 km
Average bus duration
22h 49m
Cheapest ticket price
€42
Buses per day
5
Fastest bus
27h 15m
First bus
00:25
Last bus
23:50
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Flight from €32

Bus providers: FlixBus, Lirosi Linee from Pisa to MadridYou can travel by bus between Pisa to Madrid with FlixBus, Lirosi Linee for as low as €32. When you search for schedules and tickets, Omio will show you the best journey

FlixBus

About
FlixBus is one of Europe’s leading low-cost bus companies, founded in Germany and now offering long-distance services across Europe and the United States. In addition to its extensive daytime network, FlixBus also operates overnight buses on select European routes. Standard amenities include free Wi-Fi, power outlets to charge devices, extra legroom, luggage space, and onboard toilets, with snacks and drinks available for purchase. FlixBus offers a single Standard ticket type for all routes, which includes one carry-on bag and one checked bag per passenger. Additional fees apply for extra luggage and for reserving specific seats, such as Extra Seats, Table Seats, or Panorama Seats. This combination of affordability, comfort, and wide coverage makes FlixBus a popular choice for budget-conscious travelers.
Luggage & cancellation policy
Average Duration
27h 15m
Cheapest Price
€42
Luggage included
One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Additional luggage
Additional luggage can be purchased for a fee.
Cancellation Policy
You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority boarding; Wheelchair-accessible buses.
Bikes
Bikes are allowed for a fee; must be booked.
Pets
Small pets in carriers allowed; guide dogs travel for free.

Lirosi Linee

Luggage & cancellation policy
Average Duration
27h 50m
Cheapest Price
€122
Lirosi Linee frequency
1 a day

FAQs: Bus from Pisa to Madrid

Find answers to the most common questions about traveling from Pisa to Madrid by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Madrid, this guide helps you travel smarter and with confidence.

FAQs
Cheap coach tickets from Pisa to Madrid can start from as little as €42 when you book in advance. The average coach ticket price for Pisa to Madrid is €138; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by coach from Pisa to Madrid is 27h 15m to travel the 1219 km long trip. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest coach from Pisa to Madrid leaves at 12:25 AM. Plan your trip with the Journey Planner from Omio.
The latest coach from Pisa to Madrid leaves at 11:50 PM.
There are 5 coaches a day from Pisa to Madrid which require at least one change with FlixBus, Lirosi Linee. Schedules can vary on holidays or weekends with fewer coaches.
When taking a coach from Pisa to Madrid, you can count on FlixBus, Lirosi Linee for the best way to get you to Madrid. You can also check all possible coach companies who offer a service between Pisa and Madrid and compare the amenities they offer before buying a coach ticket.
When departing from Pisa , you have various coach station options to start your trip from including Pisa, Via delle Fiamme Gialle (Park Pietrasantina), Pisa, Aeroporto Parcheggio Aurelia, Lucca, Viale Regina Margherita / Via Montanara . When arriving in Madrid , you can end your trip in coach stations like Madrid, Estación Sur de Autobuses, Madrid, Terminal de autobuses T4 (Aeropuerto de Madrid) .Passengers board the coach most frequently from Pisa, Via delle Fiamme Gialle (Park Pietrasantina), which is located around 0 away from the city centre, and they get off the coach at Madrid, Estación Sur de Autobuses, located 3 away from the city centre.
A trip to Madrid from Pisa is worth doing but not as a day trip with a journey time of 27h 15m each way. Check with Omio app the best way to travel.
The cheapest month for a coach from Pisa to Madrid is February.
It's helpful to compare your options as there are 3 ways to travel between Pisa and Madrid including taking a train, bus, and flight.
Yes, the following accessibility options are available when taking the coach from Pisa to Madrid:
  • FlixBus
    • Assistance
    • Priority boarding
    • Wheelchair-accessible buses.
Yes, there are bathrooms on board the coach from Pisa to Madrid for coach company FlixBus.
Whether you can cancel your coach ticket from Pisa to Madrid depends on the coach companies:
  • FlixBus
    • You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Yes, bikes are allowed on board the coach with coach company FlixBus.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
No, there is no food available to purchase on board the coach from Pisa to Madrid.
Yes, the following luggage options are included when booking a coach ticket from Pisa to Madrid:
  • FlixBus
    • One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Yes, the following additional luggage options are available when booking a coach ticket from Pisa to Madrid:
  • FlixBus
    • Additional luggage can be purchased for a fee.
Yes, you can bring your pet on the coach from Pisa to Madrid. The following conditions apply:
  • FlixBus
    • Small pets in carriers allowed
    • guide dogs travel for free.
You can reserve your seat on the coach from Pisa to Madrid with the following coach company: FlixBus
Yes, there are USB plugs on board the coach from Pisa to Madrid with the following coach company: FlixBus.
Yes, there is Wifi on board the coach from Pisa to Madrid with the following coach company: FlixBus.

popular bus stations

Popular bus stations from Pisa to Madrid

Pisa
Madrid
The major bus station for departures in Pisa is Pisa, Via delle Fiamme Gialle (Park Pietrasantina). Find all the information you need to know about services, amenities and connections at Pisa, Via delle Fiamme Gialle (Park Pietrasantina) for your trip from Pisa to Madrid.
Pisa, Via delle Fiamme Gialle (Park Pietrasantina)
Pisa, Aeroporto Parcheggio Aurelia
information

More options for your journey from Pisa to Madrid

Here are some other resources that might have the information you need

The Omio App Makes Travel Planning Easy

We’ll get you where you want to go. From live train updates to mobile tickets, our innovative app is the ideal way to plan and keep track of your travel.

ios-badge
android-badge
Hand With Phone