The cheapest and fastest buses from Pisa to Madrid
Cheapest price
€91
Average price
€116
Fastest journey
1 d 4 h 45 m
Average duration
1 d 11 h 21 m
Buses per day
4
Distance
1219 km
The best way to find a cheap bus ticket from Pisa to Madrid is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Pisa to Madrid will cost around €116 if you buy it on the day, but the cheapest tickets can be found for only €91.
It's difficult to get from Pisa to Madrid without transferring at least once.
FlixBus · FlixBus5:45 AM28h45Pisa, Via delle Fiamme Gialle (Park Pietrasantina)10:30 AMMadrid, Estación Sur de Autobuses€911One-way1 transfer
FlixBus · FlixBus · FlixBus11:30 PM40h05Pisa, Aeroporto Parcheggio Aurelia3:35 PMMadrid, Estación Sur de Autobuses€971One-way2 transfers
FlixBus · FlixBus · FlixBus11:30 PM39h25Pisa, Aeroporto Parcheggio Aurelia2:55 PMMadrid, Terminal de autobuses T4 (Aeropuerto de Madrid)€1371One-way2 transfers
FlixBus · FlixBus · FlixBus5:45 AM33h10Pisa, Via delle Fiamme Gialle (Park Pietrasantina)2:55 PMMadrid, Terminal de autobuses T4 (Aeropuerto de Madrid)€1411One-way2 transfers
FlixBus · FlixBus5:45 AM28h45Pisa, Via delle Fiamme Gialle (Park Pietrasantina)10:30 AMMadrid, Estación Sur de Autobuses€911One-way1 transfer
FlixBus · FlixBus · FlixBus5:45 AM33h10Pisa, Via delle Fiamme Gialle (Park Pietrasantina)2:55 PMMadrid, Terminal de autobuses T4 (Aeropuerto de Madrid)€1411One-way2 transfers
FlixBus · FlixBus · FlixBus11:30 PM39h25Pisa, Aeroporto Parcheggio Aurelia2:55 PMMadrid, Terminal de autobuses T4 (Aeropuerto de Madrid)€1371One-way2 transfers
FlixBus · FlixBus · FlixBus11:30 PM40h05Pisa, Aeroporto Parcheggio Aurelia3:35 PMMadrid, Estación Sur de Autobuses€971One-way2 transfers
Travel Information
Compare train, bus, and flight for Pisa to Madrid
Omio recommends booking the flight as it is the most popular option from Pisa to Madrid among Omio's users. If you are prioritising price take the bus with prices starting from €42. For those with little time consider booking a flight which can get you there in 3h 38m. In case you are seeking to minimise your carbon footprint the bus is your best bet as it emits only 1.2 - 3.0kg. The ticket price range depends on the travel mode: a bus costs an average of €42, and a train costs an average of €274.
Distance: 1219 km
Compare bus with
| Bus | Most popular Flight | Train |
|---|---|---|
€138 Average price Cheapest | €146 Average price | €274 Average price |
23h 19m Average total duration 22h 49m Onboard + 30m Additional time* | 6h 38m Average total duration Fastest 3h 38m Onboard + 3h 0m Additional time* | 29h 6m Average total duration 28h 36m Onboard + 30m Additional time* |
1.2 - 3.0kg CO2 emissions Lowest | 3.7 - 7.3kg CO2 emissions | - CO2 emissions |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Live departures
Pisa to Madrid bus times
The table below shows live departures for Pisa to Madrid buses for tomorrow, Tuesday, April 28. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
FlixBus · FlixBus · FlixBus | 5:45 AM Pisa, Via delle Fiamme Gialle (Park Pietrasantina) | 33h10 | 2:55 PM Madrid, Terminal de autobuses T4 (Aeropuerto de Madrid) | 2 transfers | |
FlixBus · FlixBus | 5:45 AM Pisa, Via delle Fiamme Gialle (Park Pietrasantina) | 28h45 | 10:30 AM Madrid, Estación Sur de Autobuses | 1 transfer | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Pisa to Madrid by train, bus, or flight
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Apr 28
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Why should you book Pisa to Madrid buses with Omio?
Why book with Omio vs FlixBus?
- Compare with other providers: On Omio, you can not only buy tickets for FlixBus, but also compare tickets for the likes of Lirosi Linee to find the best option for your trip from Pisa to Madrid.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare FlixBus with all available travel options, which are train, bus and flight to ensure you get the best deal for traveling from Pisa to Madrid.
Why book with Omio over Wanderu or Trainline?
- Multiple modes of transport: Omio allows you to compare travel options including train, bus and flight to find the ideal travel option from Pisa to Madrid.
Journey information
Overview: Bus from Pisa to Madrid
Buses from Pisa to Madrid run on average 5 times per day, taking around 22h 49m. Cheap bus tickets for this journey start at €42 but you can travel from only €32 by flight.
The earliest bus runs at 00:25, the last at 23:50. The fastest bus covers the 1219 km distance in 27h 15m.
Distance 1219 km |
Average bus duration 22h 49m |
Cheapest ticket price €42 |
Buses per day 5 |
Fastest bus 27h 15m |
First bus 12:25 AM |
Last bus 11:50 PM |
Cheapest Month Feb |
Cheapest Day Wed |
High Season Oct - Dec |
Low Season Jan - Mar |
Busiest Day Sun |
Least Busy Day Fri |
Best time to book 63 days |
Bus providers: FlixBus, Lirosi Linee from Pisa to MadridYou can travel by bus between Pisa to Madrid with FlixBus, Lirosi Linee for as low as €32. When you search for schedules and tickets, Omio will show you the best journey
FlixBus
Lirosi Linee
FAQs: Bus from Pisa to Madrid
Find answers to the most common questions about traveling from Pisa to Madrid by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Madrid, this guide helps you travel smarter and with confidence.

- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
- FlixBus
- Additional luggage can be purchased for a fee.
- FlixBus
- Small pets in carriers allowed
- guide dogs travel for free.
popular bus stations
Popular bus stations from Pisa to Madrid
- 06:00-23:00
- Free Wi-Fi
- Cafetería de la estación (in the station)
- Restaurante El Brillante (0.5 km)
- La Taberna de Domínguez (0.7 km).
- Available outside the main entrance.
- Elevators, ramps
- Available in the station.
- Bus: 8, 102, 148 Metro: L6 Train: C1, C5
- 06:00-23:00
- Rodilla, Mahoudrid
- Step-free access, elevators, accessible toilets
- Located inside the terminal, well-signposted, accessible, and generally clean
- No public showers in the bus station area; showers available in airport lounges (approx. €15-€30 for lounge access)
- Metro Line 8, Aeropuerto T4, 12 km
Most popular bus connections from Pisa
More options for your journey from Pisa to Madrid
Here are some other resources that might have the information you need
