The cheapest and fastest buses from Pisa to Madrid
Cheapest price
€114
Average price
€141
Fastest journey
1 d 4 h 5 m
Average duration
1 d 11 h 57 m
Buses per day
3
Distance
1219 km
The best way to find a cheap bus ticket from Pisa to Madrid is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Pisa to Madrid will cost around €141 if you buy it on the day, but the cheapest tickets can be found for only €114.
Of the 3 buses that leave Pisa for Madrid on Sat, Dec 13, 3 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Sat, Dec 13 the direct buses cover the 1219 km distance in an average of 1 d 11 h 57 m but if you time it right, some buses will get you there in just 1 d 4 h 5 m .
On Sat, Dec 13 the slowest buses will take 1 d 16 h 20 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.






Travel Information
Compare train, bus, and flight for Pisa to Madrid
Omio recommends booking the flight as it is the most popular option from Pisa to Madrid among Omio's users. If you are prioritising price take the bus with prices starting from €76. For those with little time consider booking a flight which can get you there in 2h 58m. In case you are seeking to minimise your carbon footprint the bus is your best bet as it emits only 1.2 - 3.0kg. The ticket price range depends on the travel mode: a bus costs an average of €76, and a flight costs an average of €69.
Distance: 1219 km
Compare bus with
| Bus | Most popular Flight | Train |
|---|---|---|
€144 Average price Cheapest | €325 Average price | €278 Average price |
23h 19m Average total duration 22h 49m Onboard + 30m Additional time* | 5h 58m Average total duration Fastest 2h 58m Onboard + 3h 0m Additional time* | 29h 6m Average total duration 28h 36m Onboard + 30m Additional time* |
1.2 - 3.0kg CO2 emissions Lowest | 3.7 - 7.3kg CO2 emissions | - CO2 emissions |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Live departures
Pisa to Madrid bus times
The table below shows live departures for Pisa to Madrid buses for today, Friday, December 12. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
FlixBus · FlixBus · FlixBus | 3:45 PM Pisa, Via delle Fiamme Gialle (Park Pietrasantina) | 40h20 | 8:05 AM Madrid, Estación Sur de Autobuses | 2 transfers | |
FlixBus · FlixBus · FlixBus | 3:45 PM Pisa, Via delle Fiamme Gialle (Park Pietrasantina) | 39h35 | 7:20 AM Madrid, Terminal de autobuses T4 (Aeropuerto de Madrid) | 2 transfers | |
FlixBus · FlixBus · FlixBus | 9:00 PM Pisa, Via delle Fiamme Gialle (Park Pietrasantina) | 36h30 | 9:30 AM Madrid, Estación Sur de Autobuses | 2 transfers | |
| Saturday, December 13 | |||||
![]() | 4:25 AM Pisa | 28h05 | 8:30 AM Madrid | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Pisa to Madrid by train, bus, or flight
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Dec 12
Dec 13
Dec 14
Dec 15
Dec 16
Dec 17
Dec 18
Dec 19
Dec 20
Dec 21
Dec 22
Dec 23
Dec 24
Dec 25
Dec 26
Dec 27
Dec 28
Dec 29
Dec 30
Dec 31
Jan 01
Journey information
Overview: Bus from Pisa to Madrid
Buses from Pisa to Madrid run on average 5 times per day, taking around 22h 49m. Cheap bus tickets for this journey start at €76 but you can travel from only €69 by flight.
The earliest bus runs at 00:25, the last at 23:45. The fastest bus covers the 1219 km distance in 27h 15m.
Distance 1219 km |
Average bus duration 22h 49m |
Cheapest ticket price €76 |
Buses per day 5 |
Fastest bus 27h 15m |
First bus 00:25 |
Last bus 23:45 |
Bus providers: FlixBus, Lirosi Linee from Pisa to MadridYou can travel by bus between Pisa to Madrid with FlixBus, Lirosi Linee for as low as €69. When you search for schedules and tickets, Omio will show you the best journey
FlixBus
Lirosi Linee
FAQs: Bus from Pisa to Madrid
Find answers to the most common questions about traveling from Pisa to Madrid by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Madrid, this guide helps you travel smarter and with confidence.

To find the cheapest bus tickets for your trip from Pisa to Madrid, follow these tips:
Start your search now and compare ticket prices to find the best deal!
popular bus stations
Popular bus stations from Pisa to Madrid
- 06:00-23:00
- Free Wi-Fi
- Cafetería de la estación (in the station)
- Restaurante El Brillante (0.5 km)
- La Taberna de Domínguez (0.7 km).
- Available outside the main entrance.
- Elevators, ramps
- Available in the station.
- Bus: 8, 102, 148 Metro: L6 Train: C1, C5
Most popular bus connections from Pisa
More options for your journey from Pisa to Madrid
Here are some other resources that might have the information you need
