The cheapest and fastest buses from Pisa to Prague
Cheapest price
€114
Average price
€137
Fastest journey
16 h 40 m
Average duration
19 h 5 m
Buses per day
12
Distance
771 km
The best way to find a cheap bus ticket from Pisa to Prague is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Pisa to Prague will cost around €137 if you buy it on the day, but the cheapest tickets can be found for only €114.
Of the 12 buses that leave Pisa for Prague on Sun, Dec 21, 1 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Sun, Dec 21 the direct buses cover the 771 km distance in an average of 19 h 5 m but if you time it right, some buses will get you there in just 16 h 40 m .
On Sun, Dec 21 the slowest buses will take 20 h 5 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
FlixBus
FlixBus · FlixBus · FlixBus
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FlixBus · FlixBus · FlixBusTravel Information
Compare bus, train, and flight for Pisa to Prague
Omio recommends booking the flight as it is the most popular option from Pisa to Prague among Omio's users. If you are prioritising price take the bus with prices starting from €51. For those with little time consider booking a flight which can get you there in 2h 26m. In case you are seeking to minimise your carbon footprint the bus is your best bet as it emits only 0.8 - 1.9kg. The ticket price range depends on the travel mode: a bus costs an average of €51, and a flight costs an average of €25.
Distance: 771 km
Compare bus with
| Bus | Most popular Flight | Train |
|---|---|---|
€95 Average price Cheapest | €273 Average price | €213 Average price |
17h 17m Average total duration 16h 47m Onboard + 30m Additional time* | 5h 26m Average total duration Fastest 2h 26m Onboard + 3h 0m Additional time* | 20h 44m Average total duration 20h 14m Onboard + 30m Additional time* |
0.8 - 1.9kg CO2 emissions Lowest | 2.3 - 4.6kg CO2 emissions | - CO2 emissions |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Live departures
Pisa to Prague bus times
The table below shows live departures for Pisa to Prague buses for today, Saturday, December 20. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
FlixBus · FlixBus · FlixBus | 6:10 AM Pisa, Via delle Fiamme Gialle (Park Pietrasantina) | 22h35 | 4:45 AM Praha, ÚAN Florenc | 2 transfers | |
FlixBus · FlixBus · FlixBus | 6:10 AM Pisa, Via delle Fiamme Gialle (Park Pietrasantina) | 20h05 | 2:15 AM Prague, Central Train Station | 2 transfers | |
FlixBus · FlixBus · FlixBus | 8:40 AM Pisa, Via delle Fiamme Gialle (Park Pietrasantina) | 20h35 | 5:15 AM Praha, ÚAN Florenc | 2 transfers | |
FlixBus · FlixBus · FlixBus | 8:40 AM Pisa, Via delle Fiamme Gialle (Park Pietrasantina) | 20h20 | 5:00 AM Prague, Central Train Station | 2 transfers | |
FlixBus · FlixBus · FlixBus | 10:30 AM Pisa, Via delle Fiamme Gialle (Park Pietrasantina) | 20h45 | 7:15 AM Praha, Roztyly | 2 transfers | |
FlixBus · FlixBus · FlixBus | 10:30 AM Pisa, Via delle Fiamme Gialle (Park Pietrasantina) | 21h15 | 7:45 AM Praha, ÚAN Florenc | 2 transfers | |
FlixBus · FlixBus | 3:45 PM Pisa, Via delle Fiamme Gialle (Park Pietrasantina) | 17h50 | 9:35 AM Prague, Central Train Station | 1 transfer | |
FlixBus · FlixBus · FlixBus | 3:45 PM Pisa, Via delle Fiamme Gialle (Park Pietrasantina) | 18h45 | 10:30 AM Praha, Zličín | 2 transfers | |
FlixBus · FlixBus · FlixBus | 3:45 PM Pisa, Via delle Fiamme Gialle (Park Pietrasantina) | 23h25 | 3:10 PM Praha, Černý Most | 2 transfers | |
FlixBus | 3:45 PM Pisa, Via delle Fiamme Gialle (Park Pietrasantina) | 16h40 | 8:25 AM Praha, ÚAN Florenc | 0 transfersDirect | |
FlixBus · FlixBus · FlixBus | 5:15 PM Pisa, Via delle Fiamme Gialle (Park Pietrasantina) | 21h05 | 2:20 PM Prague, Central Train Station | 2 transfers | |
FlixBus · FlixBus · FlixBus | 9:00 PM Pisa, Via delle Fiamme Gialle (Park Pietrasantina) | 19h45 | 4:45 PM Praha, ÚAN Florenc | 2 transfers | |
FlixBus · FlixBus · FlixBus | 9:00 PM Pisa, Via delle Fiamme Gialle (Park Pietrasantina) | 19h30 | 4:30 PM Prague, Central Train Station | 2 transfers | |
FlixBus · FlixBus · FlixBus | 9:00 PM Pisa, Via delle Fiamme Gialle (Park Pietrasantina) | 22h20 | 7:20 PM Praha, Na Knížecí | 2 transfers | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Pisa to Prague by bus, train, or flight
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Dec 21
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Journey information
Overview: Bus from Pisa to Prague
Buses from Pisa to Prague run on average 12 times per day, taking around 16h 47m. Cheap bus tickets for this journey start at €51 but you can travel from only €25 by flight.
There are 1 buses per day. The earliest bus runs at 01:00, the last at 23:50. The fastest bus covers the 771 km distance in 16h 40m.
Distance 771 km |
Average bus duration 16h 47m |
Cheapest ticket price €51 |
Buses per day 12 |
Direct buses 1 |
Fastest bus 16h 40m |
First bus 01:00 |
Last bus 23:50 |
Bus providers: FlixBus from Pisa to PragueYou can travel by bus between Pisa to Prague with FlixBus for as low as €25. When you search for schedules and tickets, Omio will show you the best journey
FlixBus
FAQs: Bus from Pisa to Prague
Find answers to the most common questions about traveling from Pisa to Prague by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Prague, this guide helps you travel smarter and with confidence.

To find the cheapest bus tickets for your trip from Pisa to Prague, follow these tips:
Start your search now and compare ticket prices to find the best deal!
popular bus stations
Popular bus stations from Pisa to Prague
- 00:00-23:59
- Free Wi-Fi
- Czech Bistro (in the station)
- Fast Food Express (in the station)
- Bohemian Café (0.2 km).
- Available outside the main entrance.
- Elevators, ramps
- Available in the station.
- Bus: 135, 175, 207 Metro: C Train: All major s
- 06:00-23:00
- Free Wi-Fi
- Cafeteria Florenc (in the station)
- Bistro Florenc (0.2 km)
- Restaurace U Rozvařilů (0.5 km).
- Available outside the main entrance.
- Elevators, ramps
- Available in the station.
- Bus: 133, 135, 175, 207 Metro: B, C
- Free Wi-Fi
- Café Na Knížecí (in the station)
- Bistro Praha (0.2 km)
- Restaurace U Knížete (0.5 km).
- Available outside the main entrance.
- Elevators, ramps
- Available in the station.
- Bus: 137, 176, 191 Metro: B
Most popular bus connections from Pisa
More options for your journey from Pisa to Prague
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