The cheapest and fastest buses from Pisa to Prague
Cheapest price
€90
Average price
€97
Fastest journey
16 h 15 m
Average duration
18 h 1 m
Buses per day
12
Distance
771 km
The best way to find a cheap bus ticket from Pisa to Prague is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Pisa to Prague will cost around €97 if you buy it on the day, but the cheapest tickets can be found for only €90.
Of the 12 buses that leave Pisa for Prague on Fri, Jun 19, 1 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Fri, Jun 19 the direct buses cover the 771 km distance in an average of 18 h 1 m but if you time it right, some buses will get you there in just 16 h 15 m .
On Fri, Jun 19 the slowest buses will take 19 h 30 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
FlixBus · FlixBus · FlixBus7:15 AM20h00Pisa, Via delle Fiamme Gialle (Park Pietrasantina)3:15 AMPrague, Central Train Station€901One-way2 transfers
FlixBus · FlixBus · FlixBus10:00 PM19h45Pisa, Via delle Fiamme Gialle (Park Pietrasantina)5:45 PMPraha, ÚAN Florenc€901One-way2 transfers
FlixBus · FlixBus · FlixBus5:10 PM18h35Pisa, Via delle Fiamme Gialle (Park Pietrasantina)11:45 AMPraha, Na Knížecí€901One-way2 transfers
FlixBus · FlixBus · FlixBus5:10 PM23h00Pisa, Via delle Fiamme Gialle (Park Pietrasantina)4:10 PMPraha, Černý Most€901One-way2 transfers
FlixBus · FlixBus · FlixBus6:10 PM20h25Pisa, Via delle Fiamme Gialle (Park Pietrasantina)2:35 PMPrague, Central Train Station€901One-way2 transfers
FlixBus5:10 PM16h15Pisa, Via delle Fiamme Gialle (Park Pietrasantina)9:25 AMPraha, ÚAN Florenc€971One-way0 transfers
FlixBus · FlixBus5:10 PM17h25Pisa, Via delle Fiamme Gialle (Park Pietrasantina)10:35 AMPrague, Central Train Station€1131One-way1 transfer
FlixBus · FlixBus · FlixBus5:10 PM18h20Pisa, Via delle Fiamme Gialle (Park Pietrasantina)11:30 AMPraha, Zličín€1051One-way2 transfers
FlixBus · FlixBus · FlixBus5:10 PM18h35Pisa, Via delle Fiamme Gialle (Park Pietrasantina)11:45 AMPraha, Na Knížecí€901One-way2 transfers
FlixBus · FlixBus · FlixBus10:00 PM19h30Pisa, Via delle Fiamme Gialle (Park Pietrasantina)5:30 PMPrague, Central Train Station€901One-way2 transfers
Travel Information
Compare train, bus, and flight for Pisa to Prague
Omio recommends booking the flight as it is the most popular option from Pisa to Prague among Omio's users. If you are prioritising price take the bus with prices starting from €51. For those with little time consider booking a flight which can get you there in 1h 52m. In case you are seeking to minimise your carbon footprint the bus is your best bet as it emits only 0.8 - 1.9kg. The ticket price range depends on the travel mode: a bus costs an average of €51, and a train costs an average of €196.
Distance: 771 km
Compare bus with
| Bus | Most popular Flight | Train |
|---|---|---|
€77 Average price Cheapest | €175 Average price | €212 Average price |
17h 16m Average total duration 16h 46m Onboard + 30m Additional time* | 4h 52m Average total duration Fastest 1h 52m Onboard + 3h 0m Additional time* | 20h 33m Average total duration 20h 3m Onboard + 30m Additional time* |
0.8 - 1.9kg CO2 emissions Lowest | 2.3 - 4.6kg CO2 emissions | - CO2 emissions |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Live departures
Pisa to Prague bus times
The table below shows live departures for Pisa to Prague buses for today, Thursday, June 18. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
FlixBus · FlixBus · FlixBus | 10:00 PM Pisa, Via delle Fiamme Gialle (Park Pietrasantina) | 19h45 | 5:45 PM Praha, ÚAN Florenc | 2 transfers | |
FlixBus · FlixBus · FlixBus | 10:00 PM Pisa, Via delle Fiamme Gialle (Park Pietrasantina) | 19h30 | 5:30 PM Prague, Central Train Station | 2 transfers | |
FlixBus · FlixBus · FlixBus | 10:00 PM Pisa, Via delle Fiamme Gialle (Park Pietrasantina) | 22h20 | 8:20 PM Praha, Na Knížecí | 2 transfers | |
| Friday, June 19 | |||||
FlixBus · FlixBus · FlixBus | 7:15 AM Pisa, Via delle Fiamme Gialle (Park Pietrasantina) | 20h00 | 3:15 AM Prague, Central Train Station | 2 transfers | |
FlixBus · FlixBus · FlixBus | 9:40 AM Pisa, Via delle Fiamme Gialle (Park Pietrasantina) | 21h20 | 7:00 AM Prague, Central Train Station | 2 transfers | |
FlixBus · FlixBus · FlixBus | 9:40 AM Pisa, Via delle Fiamme Gialle (Park Pietrasantina) | 20h05 | 5:45 AM Praha, ÚAN Florenc | 2 transfers | |
FlixBus · FlixBus | 5:10 PM Pisa, Via delle Fiamme Gialle (Park Pietrasantina) | 17h25 | 10:35 AM Prague, Central Train Station | 1 transfer | |
FlixBus · FlixBus · FlixBus | 5:10 PM Pisa, Via delle Fiamme Gialle (Park Pietrasantina) | 18h35 | 11:45 AM Praha, Na Knížecí | 2 transfers | |
FlixBus · FlixBus · FlixBus | 5:10 PM Pisa, Via delle Fiamme Gialle (Park Pietrasantina) | 23h00 | 4:10 PM Praha, Černý Most | 2 transfers | |
FlixBus | 5:10 PM Pisa, Via delle Fiamme Gialle (Park Pietrasantina) | 16h15 | 9:25 AM Praha, ÚAN Florenc | 0 transfersDirect | |
FlixBus · FlixBus · FlixBus | 5:10 PM Pisa, Via delle Fiamme Gialle (Park Pietrasantina) | 18h20 | 11:30 AM Praha, Zličín | 2 transfers | |
FlixBus · FlixBus · FlixBus | 6:10 PM Pisa, Via delle Fiamme Gialle (Park Pietrasantina) | 20h25 | 2:35 PM Prague, Central Train Station | 2 transfers | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Pisa to Prague by train, bus, or flight
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Jun 18
Jun 19
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Jun 21
Jun 22
Jun 23
Jun 24
Jun 25
Jun 26
Jun 27
Jun 28
Jun 29
Jun 30
Jul 01
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Jul 05
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Jul 08
Why should you book Pisa to Prague buses with Omio?
Why book with Omio vs FlixBus?
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare FlixBus with all available travel options, which are train, bus and flight to ensure you get the best deal for traveling from Pisa to Prague.
Why book with Omio over Wanderu or Trainline?
- Multiple modes of transport: Omio allows you to compare travel options including train, bus and flight to find the ideal travel option from Pisa to Prague.
Journey information
Overview: Bus from Pisa to Prague
Buses from Pisa to Prague run on average 12 times per day, taking around 16h 46m. Cheap bus tickets for this journey start at €51 but you can travel from only €23 by flight.
There are 1 buses per day. The earliest bus runs at 01:00, the last at 23:50. The fastest bus covers the 771 km distance in 16h 5m.
Distance 771 km |
Average bus duration 16h 46m |
Cheapest ticket price €51 |
Buses per day 12 |
Direct buses 1 |
Fastest bus 16h 5m |
First bus 1:00 AM |
Last bus 11:50 PM |
Cheapest Month Jul |
Cheapest Day Mon |
High Season Oct - Dec |
Low Season Apr - Jun |
Busiest Day Wed |
Least Busy Day Sat |
Best time to book 42 days |
Bus providers: FlixBus from Pisa to PragueYou can travel by bus between Pisa to Prague with FlixBus for as low as €23. When you search for schedules and tickets, Omio will show you the best journey
FlixBus
FAQs: Bus from Pisa to Prague
Find answers to the most common questions about traveling from Pisa to Prague by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Prague, this guide helps you travel smarter and with confidence.

- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
- FlixBus
- Additional luggage can be purchased for a fee.
- FlixBus
- Small pets in carriers allowed
- guide dogs travel for free.
popular bus stations
Popular bus stations from Pisa to Prague
- 00:00-23:59
- Free Wi-Fi
- Czech Bistro (in the station)
- Fast Food Express (in the station)
- Bohemian Café (0.2 km).
- Available outside the main entrance
- Elevators, ramps
- Available in the station
- Bus: 135, 175, 207 Metro: C Train: All major s
- 06:00-23:00
- Free Wi-Fi
- Cafeteria Florenc (in the station)
- Bistro Florenc (0.2 km)
- Restaurace U Rozvařilů (0.5 km).
- Available outside the main entrance
- Elevators, ramps
- Available in the station
- Bus: 133, 135, 175, 207 Metro: B, C
- Free Wi-Fi
- Café Na Knížecí (in the station)
- Bistro Praha (0.2 km)
- Restaurace U Knížete (0.5 km).
- Available outside the main entrance
- Elevators, ramps
- Available in the station
- Bus: 137, 176, 191 Metro: B
Most popular bus connections from Pisa
More options for your journey from Pisa to Prague
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